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Pamela M. McInnes Named Deputy Director of National Center for Advancing Translational Sciences 

Pamela M. McInnes, DDS, has been named deputy director of the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health. McInnes currently serves as director of the Division of Extramural Research at the National Institute of Dental and Craniofacial...

Bernard J. Tyson Assumes Role of Chairman of Kaiser Permanente

Kaiser Permanente has announced that Bernard J. Tyson officially assumed the role of Chairman of the Boards of Directors of Kaiser Foundation Hospitals and Kaiser Foundation Health Plan, Inc. Mr. Tyson was originally named by the boards in November 2012 to be the organization’s next chairman and...

Scientist/Entrepreneur Selected to Lead Tri-Institutional Therapeutics Discovery Institute

Michael A. Foley, PhD, has been selected to lead the Tri-Institutional Therapeutics Discovery Institute, Inc. (Tri-I TDI), a collaboration of Weill Cornell Medical College, The Rockefeller University, and Memorial Sloan-Kettering Cancer Center that is designed to expedite early-stage drug discovery ...

Oncology Meetings

January 2014 2014 Gastrointestinal Cancers SymposiumJanuary 16-18 • San Francisco, CaliforniaFor more information: www.gicasym.org 10th Annual Clinical Breakthroughs and Challenges in Hematologic MalignanciesJanuary 18 • Orlando, FloridaFor more information:...

Ludwig Cancer Research Contributes One-Half Billion in New Funding to Six U.S. Research Institutions 

On behalf of its founder, Daniel K. Ludwig, Ludwig Cancer Research has awarded $540 million across six Ludwig Centers, including those at Johns Hopkins University, Harvard University, the Massachusetts Institute of Technology, Memorial Sloan-Kettering Cancer Center, Stanford University, and the...

With the Goal of Curing Cancer, Ezra M. Greenspan, MD, Helped Usher in the Modern Era of Chemotherapy

Two events in Ezra M. Greenspan’s early adult life convinced him to pursue a career in medicine: the death of a college friend from pneumonia when the two were students at Cornell University College of Arts and Sciences and his own bout with the disease soon after. Saved by a local physician who...

NewYork-Presbyterian/Columbia University Medical Center Names Gary Schwartz, MD, New Chief of Hematology/Oncology 

NewYork-Presbyterian/Columbia University Medical Center has named Gary Schwartz, MD, Chief of the Division of Hematology/Oncology in the Department of Medicine and Associate Director for Research of its Herbert Irving Comprehensive Cancer Center. Dr. Schwartz assumed his new role on January 1,...

survivorship

Making Progress in Survivorship Care Planning

The recommendation that a survivorship care plan be provided to patients and their primary care providers was first presented in the 2006 Institute of Medicine (IOM) report, From Cancer Patient to Cancer Survivor: Lost in Transition. The IOM committee proposed that this document include two parts—a ...

palliative care

Assessing Patients for Palliative Care

In 2012, ASCO issued a provisional clinical opinion addressing the integration of palliative care services into standard oncology practice at the time a patient is diagnosed with metastatic or advanced cancer and for patients with uncontrolled symptoms.1 However, despite ASCO’s provisional clinical ...

Bill & Melinda Gates Foundation Names Susan Desmond-Hellman New CEO

The Bill & Melinda Gates Foundation has selected Susan Desmond-­Hellmann, MD, MPH, as its next Chief Executive Officer. Currently the Chancellor of the University of California, San Francisco (UCSF), Dr. Desmond-Hellmann will assume her role on May 1, 2014. “We chose Sue because of her...

breast cancer
gynecologic cancers
issues in oncology

Cancer Is in My Soul

The threat of getting cancer began for me before I was born. In 1950, when my mother was pregnant with me, she was diagnosed with breast cancer and refused treatment until after she gave birth, so I have always felt that cancer was woven into my soul. For the first year of my life, I was raised by...

issues in oncology

Friends of Cancer Research Launches New Online Forum: Engaging Innovation

Friends of Cancer Research recently announced the launch of the online forum Engaging Innovation (www.focr.org/EngagingInnovation). With this site, the group will host leaders from regulation, research, drug development, treatment, and advocacy, encouraging them to share insights and innovations in ...

lung cancer

Activation of Innovative Lung Cancer Master Protocol Officially Announced, Enrollment to Begin in March

At a recent meeting in Washington, DC, Friends of Cancer Research and the Engelberg Center for Health Care Reform at the Brookings Institution officially announced activation of the Lung Cancer Master Protocol, a new research strategy that has the potential to hurdle or bypass known clinical trial...

ASCO Announces Election Results for Terms Beginning June 2014

In addition to the election of Julie M. Vose, MD, MBA, FASCO, as President of the American Society of Clinical Oncology (ASCO) for a 1-year term beginning in June 2015 (see page 85), ASCO has announced four new members who were recently elected to the ASCO Board of Directors and two new members...

lung cancer

Adjuvant Gefitinib in Patients With NSCLC: Bad Idea or Wrong Patient Selection?

Despite optimal surgical resection and adjuvant chemotherapy with cisplatin-based doublets, the 5-year overall survival for patients with early-stage non–small cell lung cancer (NSCLC) remains suboptimal. In the International Association for the Study of Lung Cancer (IASLC) staging project, the...

health-care policy

Statement by ASCO President Clifford A. Hudis, MD, FACP,  on ACS Report

“The American Cancer Society [recently] issued a report showing a 20% decline in cancer death rates between 1991 and 2010, and estimating that 1.3 million deaths have been averted as a result of the decline.  “This is tremendous progress and a direct result of our nation’s commitment to cancer...

health-care policy

ASCO Statement on Annual Report to the Nation on the Status of Cancer 

Clifford A. Hudis, MD, FACP, President of ASCO, commented recently on the Annual Report to the Nation on the Status of Cancer, co-authored by the National Cancer Institute, the American Cancer Society, the Centers for Disease Control and Prevention, and the North American Association of Central...

issues in oncology

Overcoming Drug Development Challenges in the New Era of Cancer Care

While the last 15 years have brought unprecedented advances in oncology drug development, the next 10 years promise to usher in even greater opportunities to realize the goal of precision medicine in the treatment of cancer, providing patients with more effective care and better outcomes. Reaching...

Julie M. Vose, MD, MBA, FASCO, Elected ASCO President for 2015–2016 Term

Julie M. Vose, MD, MBA, FASCO, has been elected President of ASCO for a 1-year term beginning in June 2015. She will take office as President-Elect during the ASCO Annual Meeting in Chicago in June 2014. “ASCO is a very diverse and multifaceted organization with so much to offer its membership. The ...

prostate cancer

Inhibition of LAT Transporters and Leucine Uptake: A Step Forward for Therapeutic Strategies in Prostate Cancer  

The seminal study by Wang and colleagues reported in the Journal of the National Cancer Institute1 and reviewed in this issue of The ASCO Post suggests a potential new therapeutic option in the treatment of advanced prostate cancer. The authors draw attention to the reliance of cancer cells on...

ASCO Resources for Transitioning to ICD-10

ASCO has developed resources to educate and assist oncology practices in transitioning to the 10th Edition of the Center for Medicare and Medicaid Services International Classification of Diseases (ICD-10) coding system. Practices are encouraged to prepare for the transition before the October 1,...

The Conquer Cancer Foundation Celebrates 15 Years of Funding ASCO and Cancer Progress

While ASCO celebrates its 50th anniversary in 2014, the Conquer Cancer Foundation is also marking a milestone: its 15th anniversary and longtime dedication to improving the lives of people who have been touched by cancer. To accelerate progress against cancer, ASCO established the Foundation in...

The Latest Gastrointestinal Cancer News for Patients

The 2014 Gastrointestinal Cancers Symposium is taking place now. Direct your patients to www.cancer.net/gisymposium for summaries of the research being highlighted, including what the latest research means for their care. Your patients can also download or listen to a podcast with an ASCO expert...

Cancer.Net Launches New Brand of Printed Materials With Four Guides to Cancer

During the second half of 2013, four new guides to cancer, known collectively as the ASCO Answers Guides to Cancer, were released on Cancer.Net, ASCO’s patient information website. The guides to breast, prostate, lung, and colorectal cancer were completely redesigned and reimagined to help newly...

ASCO Honors New Group of Members With FASCO Distinction

Formerly called the ASCO Statesman Award, the Fellow of the American Society of Clinical Oncology (FASCO) distinction recognizes ASCO members for their extraordinary volunteer service, dedication, and commitment to ASCO. Their efforts benefit ASCO, the specialty of oncology, and, most importantly,...

issues in oncology

ASCO, AACR, and Campaign for Tobacco-Free Kids Urge FDA Prohibition of Menthol Cigarettes

ASCO has sent joint letters with both the American Association for Cancer Research (AACR) and the Campaign for Tobacco-Free Kids (CTFK) to the Food and Drug Administration (FDA) urging that the agency establish regulations to eliminate menthol in cigarettes. The agency is currently considering...

ASCO Celebrates 50 Years of Advancing Progress Against Cancer

Fifty years ago, cancer was viewed as a monolithic and largely untreatable disease, with only a handful of hard-to-tolerate and mostly ineffective therapies available. Stigma and silence left many patients with cancer with little support or information. Determined to change this, a group of seven...

breast cancer
colorectal cancer
lung cancer
prostate cancer

Ongoing NCI-Funded Clinical Trials Actively Recruiting Patients With Advanced Cancer

This issue of The ASCO Post launches a Clinical Trials Resource Guide to increase awareness of NCI-funded phase I, II, and III clinical studies for your patients with advanced cancer. All of the studies are listed on the National Institutes of Health website at ClinicalTrials.gov. The clinical...

issues in oncology

ESMO Releases Position Paper on Med-Oncs' Role in Cancer Care

A new position statement from the European Society for Medical Oncology (ESMO) reports that medical oncologists have a vital role to play in cancer care.1 According to the position statement, medical oncologists are specialist cancer physicians trained to provide treatment with drugs, spanning from ...

breast cancer

Cautious Comments on the TARGIT-A Trial

Numerous randomized trials have demonstrated that whole-breast irradiation plays an important role after breast-conserving surgery for invasive breast cancer. A recent meta-analysis of these trials indicated that whole-breast irradiation decreased the risk of total breast cancer relapse events and...

lung cancer

American Lung Association Applauds U.S. Preventive Services Task Force Recommendation of Screening for Those at High Risk of Lung Cancer

The American Lung Association issued the following statement on December 31, 2013, in response to the recommendation of the U.S. Preventive Services Task Force (USPSTF) to screen individuals at high risk of lung cancer. “The [USPSTF] made a recommendation that will save lives. The Task Force...

lung cancer

Molecularly Targeted Therapy for Lung Cancer

INSIDE THE BLACK BOX is an occasional column offering insight into the FDA and its policies and procedures. This installment addresses a changing paradigm in the treatment of lung cancer, exemplified by concurrent approval of a companion diagnostic with each of several new targeted agents or new...

multiple myeloma

IFM 2005-02 Update Differs From CALGB 100104: Why? 

The updated analysis of the Intergroupe Francophone du Myelome (IFM) 2005-02 trial in newly diagnosed multiple myeloma patients showed that lenalidomide (Revlimid) maintenance prolongs progression-free survival after stem cell transplantation, but does not improve overall survival, according to...

kidney cancer

Tivozanib Improves Progression-Free but Not Overall Survival vs Sorafenib in Metastatic Renal Cell Carcinoma

The investigational agent tivozanib is a selective tyrosine kinase inhibitor of vascular endothelial growth factor receptor (VEGFR)-1, -2, and -3. In a phase III trial reported in the Journal of Clinical Oncology by Robert J. Motzer, MD, of Memorial Sloan-Kettering Cancer Center (MSKCC), and...

gynecologic cancers

Genetic Flaw That Drives Some Ovarian Cancers Identified

Researchers at Dana-Farber Cancer Institute, Boston, have identified an overactive gene that drives about one-third of high-grade serous ovarian tumors—the most common and malignant type of ovarian cancer. The gene, GAB2, isn’t mutated or abnormal, but triggers cancerous cell growth because the...

Expert Point of View: Debu Tripathy, MD

Debu Tripathy, MD, Professor of Medicine, Co-Leader of the Women’s Cancer Program, and the Priscilla and Art Ulene Chair in Women’s Cancer at the University of Southern California Norris Cancer Center, Los Angeles, commented on the APT study for The ASCO Post. “In treating early-stage...

breast cancer

HER2-Positive Breast Cancer Patients With Small Tumors Benefit From Low-Toxicity Regimen 

There may be a benefit for treating small HER2-positive tumors—a breast cancer subset for whom treatment recommendations have not been established but for whom there is still risk of recurrence—and this can be done with little toxicity, according to a multicenter study presented at the 2013 San...

breast cancer

Seven Studies at SABCS Make Dr. Jame Abraham's List of 'Practice-Changing' Talks

From December 10 to 14, the American Association for Cancer Research, the Cancer Therapy & Research Center at The University of Texas Health Sciences Center at San Antonio, and Baylor College of Medicine once again hosted the San Antonio Breast Cancer Symposium (SABCS), presenting...

breast cancer

Philips Receives FDA Clearance for Spectral Breast Density Measurement Application

Royal Philips has announced that that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for the Spectral Breast Density Management Application for its MicroDose SI full-field digital mammography system. The application is the first spectral breast density measurement ...

geriatric oncology

International Society of Geriatric Oncology Meeting Explores Multidisciplinary, Tailored Treatment of Older Patients With Cancer

The annual meeting of the International Society of Geriatric Oncology (SIOG, www.siog.org) was held in Copenhagen from October 24 to 26. The theme of the meeting was the “Multidisciplinary Approach Towards Personalized Treatments.” The Society, which was founded in 2000, is a multidisciplinary...

ASCO's 50th Anniversary and the Road Ahead

As the American Society of Clinical Oncology celebrates its 50th anniversary, ASCO’s Chief Executive Officer Allen S. Lichter, MD, FASCO, recently talked with The ASCO Post about the Society’s past, present, and future. Important Milestone What are your thoughts about ASCO’s origins and its 50th...

breast cancer

Artemis Project® for a Preventive Breast Cancer Vaccine

I read with interest the article, “Breast Cancer Vaccines for Primary Prevention Move Toward Clinical Use,” which appeared in the December 15th issue of The ASCO Post (page 28). However, information presented regarding the National Breast Cancer Coalition’s (NBCC’s) Artemis Project for a breast...

Oncology Meetings

FEBRUARY 25th International Congress on Anti-Cancer TreatmentFebruary 4-6 • Paris, FranceFor more information: www.icact.fr APOS 11th Annual ConferenceFebruary 13-15 • Tampa, FloridaFor more information:www.apos-society.org/apos2014/ European Society for Medical Oncology Sarcoma and GIST...

Champions Oncology Names Chief Medical Officer

Champions Oncology, a company engaged in the development of advanced technology solutions and services to personalize the development and use of oncology drugs, has announced the appointment of Angela Davies, MD, as Chief Medical Officer. Dr. Davies has demonstrated experience in both academic...

Texas Children’s Hospital Announces New Chief of Interventional Radiology

The Department of Pediatric Radiology at Texas Children’s Hospital recently announced that Kamlesh U. Kukreja, MD, has been named the new Chief of Interventional Radiology. Dr. Kukreja has also been appointed as Assistant Professor of Radiology at Baylor College of Medicine. “For more than a...

Expect Questions, and Some Reluctance, About Getting a Flu Shot

People with weakened immune systems due to diseases like cancer are at increased risk of severe complications from the flu virus and should get flu shots annually. The Centers for Disease Control and Prevention (CDC) strongly encourages this practice, and most oncologists would recommend that for...

supportive care

Cancer Patients Are at Increased Risk of Complications From the Flu and Should Receive Flu Shots, but Not the Nasal Spray

Widespread influenza activity continues to be reported by the Centers for Disease Control and Prevention (CDC), with a recent increase in flu-related hospitalizations.1,2 Patients with cancer are at increased risk from flu complications and should receive the flu shot, but not the flu nasal spray...

Grant to Develop Website and Mobile App to Track Radiation Therapy Toxicity Awarded to Radiation Oncology Resident

The Radiation Oncology Institute has selected Malolan S. Rajagopalan, MD, a radiation oncology resident at the University of Pittsburgh Cancer Institute, to receive a $20,000 grant for a project to compile best practices regarding the management of radiation therapy toxicity. Dr. Rajagopalan’s...

cns cancers

An Overview of the REGAL Trial and Anti-VEGF Therapies in Recurrent Glioblastoma

As published in the Journal of Clinical Oncology by Batchelor and colleagues1 and reviewed in a recent issue of The ASCO Post (November 15, 2013, page 106), the REGAL trial was a randomized, phase III, placebo-controlled, partially blinded trial evaluating the efficacy of cediranib, an...

Major Cancer Milestones in History, From ASCO’s CancerProgress.Net

To help tell the story of progress against cancer, ASCO launched CancerProgress.Net in 2011. The site is intended as a resource for media, policymakers, oncologists, advocates, and the public. One central feature of the site is an interactive timeline of major milestones in cancer treatment,...

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