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Survivorship

Risk of Subsequent Neoplasms in Survivors of Childhood Neuroblastoma

In a Dutch study reported in the Journal of Clinical Oncology, Westerveld et al identified long-term risks of subsequent neoplasms in 5-year survivors of childhood neuroblastoma. Study Details The study included data from 563 survivors in the Dutch Childhood Cancer Survivor Study–LATER cohort...

Survivorship
Issues in Oncology
Solid Tumors

Large Proportion of Childhood Cancer Survivors May Experience Significant Fear of Cancer Recurrence

Investigators have found that one-third of adult survivors of childhood cancers may experience a severe fear of cancer recurrence that impacts their daily lives, according to a recent study published by Pizzo et al in JAMA Network Open. Background Although the number of survivors of childhood...

Survivorship

Association of Excess Body Weight and Risk of Second Primary Cancers Among Survivors of First Primary Cancers

In a study reported in JAMA Network Open, Bodelon et al found that survivors of first primary cancers with overweight or obesity were at increased risk for second primary cancers, particularly obesity-related cancers. Study Details The study focused on data from the Cancer Prevention Study II...

Breast Cancer
Survivorship
Genomics/Genetics
Issues in Oncology

Common Breast Cancer Treatments May Speed Aging Process

Researchers have found that common breast cancer treatments—including chemotherapy, radiation, and surgery—may accelerate the biological aging process among breast cancer survivors, according to a new study published by Carroll et al in the Journal of the National Cancer Institute. The findings...

Solid Tumors
Issues in Oncology
Health-Care Policy
Survivorship

ACA’s Dependent Coverage Expansion May Have Benefited Young Adult Patients Diagnosed With Cancer

Investigators have uncovered that during the Patient Protection and Affordable Care Act’s (ACA) first decade, the survival rates of Dependent Coverage Expansion–eligible young adult patients with cancer may have improved, according to a recent study published by Roth et al in Cancer. The federal...

Survivorship
Cardio-oncology

Cancer and Cancer-Related Therapy May Increase Cardiovascular Disease Risk in Older Cancer Survivors

Investigators have uncovered a higher risk for strokes, heart attacks, and hospital admissions for heart failure in older cancer survivors, according to a recent study published by Muhandiramge et al in Cancer. Background Although advances in cancer treatment have led to decreased mortality rates...

Breast Cancer
Survivorship
Issues in Oncology

Sexual Health Symptoms May Be Linked to Poor Adherence to Adjuvant Endocrine Therapy in Black Women With Breast Cancer

Symptoms related to sexual health may be associated with decreased adherence to adjuvant endocrine therapy among Black women with early-stage breast cancer, according to new findings presented by Anderson et al at the 2024 American Association for Cancer Research (AACR) Conference on the Science of ...

Breast Cancer
Survivorship
Genomics/Genetics
Issues in Oncology

Two Recent Studies Provide Evidence That Breastfeeding After Breast Cancer May Be Safe

Women who breastfeed after treatment for breast cancer—including those with germline BRCA-mutated disease—may not be at increased risk of cancer recurrence or new breast cancers, according to two recent international studies presented by Blondeaux et al (Abstract 1815O) and Peccatori et al...

CNS Cancers
Survivorship
Issues in Oncology

Early Interventions May Improve Long-Term Academic Achievement in Pediatric Brain Tumor Survivors

Investigators have found that providing early developmental resources may help reduce the adverse effects of brain tumors and cancer therapy on the academic achievement of young pediatric cancer survivors, according to a recent study published by Somekh et al in the Journal of the National Cancer...

Gynecologic Cancers
Leukemia
Survivorship

Births and Adverse Obstetric Outcomes Among Female Survivors of Adolescent and Young Adult Cancers

In a population-based retrospective cohort study (Teenage and Young Adult Cancer Survivor Study; TYACSS) reported in The Lancet Oncology, Sunguc et al identified risks of adverse obstetric outcomes among female survivors of adolescent and young adult cancers in England and Wales. Study Details The...

Issues in Oncology
Survivorship

Preserving Reproductive Health for Patients With Cancer: Insights From an Oncofertility Patient Navigator

Advancements in cancer therapies have led to increased survival rates, but this progress has come with a cost: many life-saving treatments may impair fertility, leaving patients and cancer survivors grappling with the potential loss of their reproductive abilities. Oncofertility, a field that...

Breast Cancer
Survivorship
Genomics/Genetics

Are Eligible Breast Cancer Survivors Receiving Genetic Testing?

Researchers have found that many eligible breast cancer survivors may not be receiving genetic counseling and testing, according to a recent study published by Katz et al in the Journal of Clinical Oncology. Background A growing proportion of cancer treatment and survivorship care relies on...

Survivorship
Issues in Oncology

Survivorship Standards at Commission on Cancer–Accredited Cancer Care Facilities

Only a minority of adult cancer survivors may have access to specialized survivorship services such as those addressing fertility and sexual health issues, and having survivorship standards in place may help cancer centers better provide services that meet the distinct needs of these patients,...

Survivorship
Supportive Care
Cardio-oncology

Can Adhering to a Mediterranean Diet Reduce Mortality in Cancer Survivors?

Cancer survivors who adhere to a Mediterranean diet may survive longer and have a reduced risk of cardiovascular-related mortality compared with those who had lower adherence to the diet, according to a recent study published by Bonaccio et al in JACC: CardioOncology. Background The Mediterranean...

Gynecologic Cancers
Leukemia
Survivorship

Risk of Adverse Obstetric Outcomes in Adolescent and Young Adult Cancer Survivors

In an English and Welsh study (The Teenage and Young Adult Cancer Survivor Study) reported in The Lancet Oncology, Sunguc et al found that cervical cancer and leukemia survivors have a heightened risk of experiencing several serious obstetric complications. “Therefore, any pregnancy [in these...

Survivorship
Issues in Oncology

Impact of Cisplatin-Based Chemotherapy on Hearing in Cancer Survivors

Researchers have uncovered the long-term effects of cisplatin-based chemotherapy on the hearing of cancer survivors, according to a recent study published by Sanchez et al in JAMA Oncology. Background Cisplatin is commonly used in chemotherapy to treat a variety of cancer types, including...

Breast Cancer
Survivorship

Long-Term Study Finds Most Breast Cancer Survivors Were Able to Preserve Fertility and Achieve Pregnancy After Diagnosis

Research examining fertility and attempts at pregnancy among young women after a breast cancer diagnosis has been hampered by short-term follow-up and a lack of prospective assessment of pregnancy attempts. However, a long-term study investigating fertility outcomes among young women who reported...

Issues in Oncology
Survivorship

LGBTQ+ Cancer Survivors Have a Higher Burden of Chronic Health Conditions, Disabilities Than Non-LGBTQ+ Cancer Survivors

Although improvements in the early detection and treatment of cancer have reduced cancer-related mortality rates and increased the number of cancer survivors in the United States to over 18 million, not all patients with the disease are benefiting from these advances. A recent study investigated...

Breast Cancer
Cardio-oncology
Survivorship

Cardiac Dysfunction Among Breast Cancer Survivors

In a study reported in the Journal of Clinical Oncology, Bostany et al found that the cumulative incidence of cardiac dysfunction reached 15.3% at 15 years from the start of cardiotoxic treatments in breast cancer survivors. Study Details The study involved patients at the Next Steps Breast Cancer...

Cardio-oncology
Survivorship

Childhood Cancer Survivors: Burden of Cardiovascular Disease and Risk of Major Cardiovascular Events

In an analysis from the St. Jude Lifetime Cohort Study (SJLIFE) reported in The Lancet Oncology, Hammoud et al found that survivors of childhood cancer had a greater risk of major adverse cardiovascular events vs matched community controls, and that an increasing burden of nonmajor events increased ...

Survivorship

Apply Through July 31, 2024, for Survivorship Champion’s Prize

Children’s Cancer Cause, a national advocacy group in pioneering research and innovation for pediatric cancer, announced it is accepting applications for the Survivorship Champion’s Prize. This award is presented to a group, program, or institution that has demonstrated significant advancements in...

Survivorship

Study Explores How Partner Relationships Impact the Well-Being of Breast Cancer Survivors

Diagnosis and treatment of breast cancer place significant stress on survivors, their partners, and their relationships. A recent study from researchers at the Regenstrief Institute and Indiana University (IU)’s Schools of Nursing, Science, and Medicine is one of the first to examine the impact of...

Breast Cancer
Survivorship

Most Breast Cancer Survivors Able to Achieve Pregnancy After Diagnosis, Study Finds

Research examining fertility preservation and pregnancy attempts among young women following a breast cancer diagnosis has been hampered by short-term follow-up and a lack of prospective assessment of pregnancy attempts. A new long-term study investigating fertility outcomes among young women who...

Breast Cancer
Supportive Care
Survivorship

Donepezil for the Treatment of Cognitive Impairment in Breast Cancer Survivors After Adjuvant Chemotherapy

In the phase III WF-97116 trial reported in the Journal of Clinical Oncology, Rapp et al found that treatment with the cognitive enhancer donepezil did not improve memory or other cognitive functions vs placebo in breast cancer survivors with cancer-related cognitive impairment 1 to 5 years after...

Genomics/Genetics
Survivorship

Childhood Cancer Survivors: Genetic Risk Factors for Treatment-Related Type 2 Diabetes Mellitus

In a study reported in the Journal of Clinical Oncology, Im et al found that genetic variants associated with a risk of treatment-related type 2 diabetes mellitus among childhood cancer survivors of African or European ancestry posed a higher risk of diabetes among those of African ancestry. As...

Prostate Cancer
Survivorship

Effect of Radiation Therapy Timing on Lifespan of Artificial Urinary Sphincters in Prostate Cancer Survivors

Researchers have shown that adjuvant radiation therapy rather than salvage radiation therapy may improve the function of artificial urinary sphincters for stress urinary incontinence in patients who have undergone surgery for prostate cancer, according to new findings presented by Gaines et al at...

Breast Cancer
Survivorship
Supportive Care

Aspirin Use Among Breast Cancer Survivors: Navigating Negative Results, Age, and Health Equity

Investigators uncovered critical issues related to health equity and aging that may have broad implications for cancer trials among breast cancer survivors receiving aspirin, according to a recent study published by Mandelblatt et al in JAMA. Study Methods and Results In the recent study, the...

Leukemia
Survivorship

Impact of Propofol Exposure on Neurocognitive Outcomes in Children With High-Risk ALL

In an analysis from the Children’s Oncology Group phase III AALL1131 study reported in the Journal of Clinical Oncology, Alexander et al found that exposure to propofol was associated with an increased risk of impairment in reaction time/processing speed at 1 year after treatment in children with...

Cost of Care
Survivorship

Financial Hardships Caused by Cancer Are Long-Lasting for Many Working-Age Adults

Research shows that the average cost of medical care and drugs can top $42,000 in the first year following a cancer diagnosis, with the cost of some treatments, including chimeric antigen receptor T-cell therapies, exceeding $1 million. For many cancer survivors, these costs can have a lingering...

Breast Cancer
Survivorship
Issues in Oncology

Breast Cancer Survivors: Relationship Satisfaction and Emotional and Physical Well-Being

Investigators have uncovered that the emotional and physical health of breast cancer survivors may be influenced by their relationship with their partners, according to a recent study published by Vachon et al in Healthcare. Background The diagnosis and treatment of breast cancer often place...

Breast Cancer
Survivorship
Cardio-oncology

Observing a Healthy Diet May Reduce Risk of Cardiovascular Disease in Breast Cancer Survivors

Following a healthy diet may reduce the risk of cardiovascular disease in female breast cancer survivors, according to a recent study published by Ergas et al in JNCI Cancer Spectrum. Background Cardiovascular disease is one of the leading causes of non–breast cancer–related mortality among...

Survivorship

Functional Disability Among U.S. Cancer Survivors, 2017–2022

In a study reported in the Journal of Clinical Oncology, Cao et al found that U.S. adult cancer survivors had higher levels of mobility disability and self-care disability than adults without a cancer diagnosis. Study Details The study focused on data from 47,768 adult cancer survivors (aged ≥ 18...

Supportive Care
Survivorship

Effect of Virtually Delivered CBT for Insomnia on Cancer-Related Cognitive Impairment

In a Canadian study reported in the Journal of Clinical Oncology, Sheila N. Garland, PhD, and colleagues found that virtually delivered cognitive behavioral therapy for insomnia (CBT-I) improved perceived cancer-related cognitive impairment (CRCI) vs waiting list controls in cancer survivors. Study ...

Global Cancer Care
Survivorship

Cancer Prevalence in Europe as of 2020

In a study reported in The Lancet Oncology, De Angelis et al estimated the numbers of patients alive after a cancer diagnosis in Europe as of 2020.   Study Details The study used data from the EUROCARE-6 study to estimate the prevalence of cancer in 29 European countries and the 27 countries in the ...

Head and Neck Cancer
Survivorship

Risk of Stroke in Survivors of Head and Neck Cancer

In a Singaporean study reported in JAMA Network Open, Yip et al found that survivors of head and neck cancer were at an increased risk of stroke compared with the general population. Study Details The registry-based cross-sectional study involved 9,803 survivors—excluding those with a history of...

Breast Cancer
Lymphoma
Survivorship

Doxorubicin Exposure and Risk of Breast Cancer in Survivors of Hodgkin Lymphoma

In a Dutch study reported in the Journal of Clinical Oncology, Neppelenbroek et al found that doxorubicin treatment was associated with an increased risk of breast cancer among adolescent and adult Hodgkin lymphoma survivors. Study Details The study involved a cohort of 1,964 female 5-year Hodgkin...

Survivorship
Pain Management

Can Physical Activity Lessen Pain Intensity in Cancer Survivors?

Physical activity may help lessen the intensity of pain in cancer survivors, according to a recent study published by Swain et al in Cancer. Background Current U.S. guidelines regarding physical activity recommend that individuals receive 150 to 300 minutes of moderate-intensity exercise per week,...

Solid Tumors
Survivorship
Cardio-oncology

Novel Biomarker in Cancer Survivors May Be Linked to Higher Risk of Mortality

Elevated N-terminal pro–brain natriuretic peptide (NT-proBNP) levels may be associated with a higher risk of mortality among cancer survivors, according to a recent study published by Cao et al in the Journal of the National Cancer Institute. NT-proBNP—produced in response to the stretching of...

Survivorship
Cardio-oncology

Survivors of Childhood Cancer With High Anthracycline Exposure: Can a Beta-Blocker Improve Cardiac Function?

In a U.S./Canadian phase IIb trial (PREVENT-HF) reported in The Lancet Oncology, Armenian et al found that the beta-blocker carvedilol did not significantly improve cardiac function—measured as standardized left ventricular wall thickness–dimension ratio Z score (LVWT/Dz)—vs placebo in survivors of ...

Supportive Care
Survivorship

Study Finds Plant-Rich Foods, Nuts/Seeds May Benefit Childhood Cancer Survivors

A recent study, published by Wang et al in the Journal of Clinical Oncology, conducted as part of the St. Jude Lifetime Cohort (SJLIFE), may provide new insights into how diet may affect aging in adult survivors of childhood cancer. This study, involving 3,322 participants aged 18 to 65, found that ...

Issues in Oncology
Survivorship

Prevalence of Substance Use Disorders Among U.S. Adult Cancer Survivors

In a study reported in JAMA Oncology, Jones et al found a prevalence of active substance use disorders of 3.8% among U.S. adult survivors of solid tumor cancers, with higher rates among those with head/neck, esophageal/gastric, and cervical cancers as well as melanoma. Study Details The study used...

Survivorship
Cardio-oncology

Use of Carvedilol to Help Prevent Heart Failure in Childhood Cancer Survivors

Researchers discovered that the blood vessel–relaxing agent carvedilol may be safe and effective at reducing the risk of heart failure in childhood cancer survivors, according to a recent study published by Armenian et al in The Lancet Oncology. These findings indicate carvedilol may improve...

Survivorship

Incidence of Second Primary Cancers in Adult Cancer Survivors

In a Danish population-based retrospective cohort study reported in The Lancet Oncology, Kjaer et al identified the cumulative incidence of second primary cancers among cancer survivors aged ≥ 40 years who were alive 1 year after diagnosis.   Study Details The study involved data from 457,334...

Survivorship
Cardio-oncology

Is Prediabetes Linked to Cardiovascular and Kidney Diseases in Adult Survivors of Childhood Cancer?

In a study reported in the Journal of Clinical Oncology, Dixon et al found that adult survivors of childhood cancers with prediabetes were at an increased risk of developing cardiovascular events and chronic kidney disease. The study involved data from 3,529 ≥ 5-year survivors of childhood cancer...

Breast Cancer
Survivorship

Some Breast Cancer Survivors May Safely De-escalate Mammography 3 Years After Surgery

Women aged 50 or older who had less-frequent mammography 3 years after curative surgery for early-stage breast cancer had similar outcomes as women who had annual mammography, according to results from the Mammo-50 trial presented at the 2023 San Antonio Breast Cancer Symposium (Abstract GS03-02)....

Survivorship

Predicting Primary Ovarian Insufficiency in Childhood Cancer Survivors

As reported in The Lancet Oncology, Im et al have developed risk-prediction models for primary ovarian insufficiency in long-term survivors of childhood cancer. Study Details In the study, models to predict age-specific risk of primary ovarian insufficiency were evaluated among 5-year survivors...

Colorectal Cancer
Survivorship
Supportive Care

Consuming Navy Beans May Improve Gut Health, Regulate Immune and Inflammatory Processes in Colorectal Cancer Survivors

Researchers have uncovered that the regular consumption of navy beans may help modulate markers linked to obesity and disease and improve the gut microbiome in colorectal cancer survivors, according to a novel study published by Zhang et al in eBioMedicine. Background Obesity, poor diet, and...

Colorectal Cancer
Survivorship

Risk of Subsequent Colorectal Cancer After Abdominopelvic Radiotherapy Among Childhood Cancer Survivors

In a European study reported in the Journal of Clinical Oncology, Heymer et al found that the risk of subsequent colorectal cancer was elevated among childhood cancer survivors who had undergone abdominopelvic radiotherapy. Study Details The study used data from the PanCareSurFup Study—a...

Survivorship

Survivors of Childhood Cancer: Study Shows Heart-Related Ailments Linked to Radiotherapy Dose

Research on the advances in radiation modeling presented by Rebecca M. Howell, PhD, at the 2023 American Society for Radiation Oncology (ASTRO) Annual Meeting may provide insights into the late cardiac effects of survivors of childhood cancer in the Childhood Cancer Survivor Study (CCSS).1 Dr....

Cost of Care
Survivorship

Role of Crowdfunding Campaigns in Covering Medical Expenses for Cancer Survivors

Investigators have discovered that cancer survivors in the United States may be increasingly utilizing crowdfunding campaigns like GoFundMe to help cover the costs of medical and other basic household expenses, according to new findings presented by Zheng et al and Yu et al at the 2023 ASCO Quality ...

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