SBRT May Provide Superior Pain Relief From Spinal Metastases vs Conventional Radiotherapy
Stereotactic body radiation therapy was superior to conventional radiation therapy in reducing pain from spinal metastases in a phase II/III study...
SBRT for Multiple Lung Metastases: How Many Treatment Sessions Are Optimal?
Delivering stereotactic body radiation therapy in either one or four treatment sessions led to similar outcomes in patients with up to three lung metastases in the randomized SAFRON II trial...
Radiotherapy With Cisplatin vs Cetuximab in Previously Untreated Patients With Locoregionally Advanced Head and Neck Cancer
The ARTSCAN III trial found that radiotherapy with concomitant cetuximab did not improve outcomes in previously untreated, locoregionally advanced head and neck squamous cell carcinoma...
USPSTF Issues Draft Recommendation on Screening for Colorectal Cancer
On October 27, the U.S. Preventive Services Task Force (USPSTF) posted a draft recommendation statement on screening for colorectal cancer...
ASCO Coronavirus Resources
As the coronavirus (COVID-19) continues to spread, ASCO is committed to providing the most current information and resources to its members and the larger oncology...
Kristen Whitaker: Should Body Mass Index Guide the Choice of Chemotherapy in Patients With Breast Cancer?
Erika Ramsdale and colleagues: COVID-19, Cancer, and the Older Adult
Govind Persad: How Telemedicine Is Impacting Oncology Care During the COVID-19 Pandemic
Nathalie McKenzie: The Gut, Our Choices, and Gynecologic Cancers
Princess Dina Mired: Mobilizing for Greater Equity in Health Care Despite the Challenges of COVID-19
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Treatment and Sequencing in Metastatic Castration-Resistant Prostate Cancer
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Recent Advances in the Treatment of FGFR-Altered Advanced Cholangiocarcinoma
Sexual Health Often Overlooked in Cancer Survivorship Care
A new study points to a need for oncologists to ask their patients about sexual health after chemotherapy, radiation, and other cancer treatments. In a survey of nearly 400 cancer survivors, 87% said they experienced sexual side effects, but most also said their oncologist had not formally asked...
Impact of Genes on Total Number and Type of Nevi
A study by Duffy et al in the Journal of Investigative Dermatology reported on specific gene variations affecting the number and types of moles on the body and their role in causing skin cancer. “The goal was to investigate the genetic underpinnings of different mole classes, or...
Addition of Oxaliplatin to Preoperative Capecitabine-Based Chemoradiation and Adjuvant Capecitabine in Locally Advanced Rectal Cancer
As reported in the Journal of Clinical Oncology by Schmoll et al, the phase III PETACC 6 trial has shown no benefit of the addition of preoperative and adjuvant oxaliplatin to preoperative capecitabine-based chemoradiation and adjuvant capecitabine in patients undergoing total mesorectal excision...
Neoadjuvant Dual Checkpoint Blockade in Certain Patients With Localized Bladder Cancer
Neoadjuvant combination therapy with the anti–CTLA-4 therapy tremelimumab and the anti–PD-1 therapy durvalumab was well tolerated and showed early signs of activity in patients ineligible to receive cisplatin-based chemotherapy, all of whom had tumors with high-risk features that are associated...
Gemcitabine/Eribulin in Cisplatin-Ineligible Metastatic Urothelial Carcinoma
In the final analysis from a phase II California Cancer Consortium trial (NCI-9653) reported in the Journal of Clinical Oncology, Sadeghi et al found the combination of gemcitabine and eribulin showed activity in cisplatin-ineligible patients with metastatic urothelial carcinoma. Study Details...
Swedish Study of HPV Vaccination and Risk of Invasive Cervical Cancer
In a study reported in The New England Journal of Medicine, Lei et al found that receipt of the quadrivalent human papillomavirus (HPV) vaccine among girls and young women was associated with a substantial reduction in the risk of invasive cervical cancer. As stated by the investigators, “The...
Deintensified Chemoradiotherapy for HPV-Associated Oropharyngeal Squamous Cell Carcinoma
In a phase II trial reported in the Journal of Clinical Oncology, Chera et al found that deintensified chemoradiotherapy produced favorable outcomes in human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma. Study Details In the multicenter trial, 114 patients were recruited...
