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Breast Cancer
Genomics/Genetics

New Genetic Test May Predict Response to Immunotherapy in Triple-Negative Breast Cancer

The search for biomarkers of response to immunotherapy is high on the list of cancer-related research efforts. A new classifier in triple-negative...

Neha Vapiwala, MD, FACR, FASTRO, FASCO, Voted President-Elect of ASTRO

The members of the American Society for Radiation Oncology (ASTRO) recently elected five new officers to ASTRO’s Board of Directors...

Gynecologic Cancers

How Does Endometriosis Typology Influence Ovarian Cancer Risk?

In a Utah population–based cohort study reported in JAMA Network Open, Barnard et al found that women with ovarian endometriomas...


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Hematologic Malignancies

Donor Socioeconomic Status May Influence Outcomes in Hematopoietic Cell Transplantation

Investigators have demonstrated that the socioeconomic status of cell donors may impact the health outcomes of patients with hematologic malignancies...

Breast Cancer

Electronic Health Record–Based Prompt May Help Reduce Breast Cancer Overtreatment

Researchers have developed a novel prompt, embedded in electronic health records, to flag older patients with early-stage breast cancer...

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Hematologic Malignancies

Rami S. Komrokji, MD, on Myelodysplastic Neoplasms: Classifying Risks Among Subsets of Disease

Breast Cancer

Capivasertib With Fulvestrant for Previously Treated Advanced Hormone Receptor–Positive, HER2-Negative Breast Cancer

On November 16, 2023, capivasertib (Truqap) was approved for use with fulvestrant for patients with hormone receptor–positive, HER2-negative locally advanced or metastatic breast cancer with one or more PIK3CA/AKT1/PTEN alterations, following disease progression on at least one endocrine-based...

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Can Living in a Disadvantaged Area Increase the Risk of Aggressive Prostate Cancer?

Those living in disadvantaged neighborhoods have significantly higher activity of stress-related genes, new research suggests, which in turn may contribute to higher rates of aggressive prostate cancer in African American men. These findings were published by Boyle et al in JAMA Network Open....

Paolo Corradini, MD, on PMBCL and DLBCL: Comparing Outcomes With Axicabtagene Ciloleucel

Supportive Care
Issues in Oncology

Breaking the Silence: Addressing Sexual and Reproductive Health in Cancer Care

For patients with cancer and cancer survivors, sexual dysfunction and reproductive health concerns are often the elephant in the exam room—a significant quality-of-life issue that both patients and clinicians struggle to discuss openly and effectively. At the recent NCCN Policy Summit on Sexual and ...

Leukemia

Having Acute Lymphoblastic Leukemia Took Away My Fear of Death

On May 30, 2017, 9 days before I turned 19 and soon after I had completed my sophomore year at college, I was diagnosed with aggressive acute lymphoblastic leukemia. But getting to the diagnosis was a tortuous process. I had been feeling fatigued and losing weight for several weeks prior to the...

Are Eligible Breast Cancer Survivors Receiving Genetic Testing?

Researchers have found that many eligible breast cancer survivors may not be receiving genetic counseling and testing, according to a recent study published by Katz et al in the Journal of Clinical Oncology. Background A growing proportion of cancer treatment and survivorship care relies on...

Hematologic Malignancies
Leukemia

Nigel Russell, MD, on Acute Myeloid Leukemia: New Findings on FLAG-Ida and Gemtuzumab Ozogamicin

Hematologic Malignancies
Supportive Care

Chronic Graft-vs-Host Disease: Clinical Trial Updates

Chronic graft-vs-host disease, an immune-mediated disorder that follows allogeneic hematopoietic cell transplantation (allo-HCT), is characterized by debilitating tissue injury with inflammatory and fibrotic pathology leading to significant morbidity and mortality. Historically, the treatment of...

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Uncovering the Genetic Risk of Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome

Some patients with a genetic predisposition for cancer may not qualify for genetic screenings under the current guidelines, according to a recent study published by Samadder et al in JCO Precision Oncology. Researchers are investigating how to advance personalized medicine and tailor prevention and ...

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