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issues in oncology
cost of care
lung cancer
gynecologic cancers

Two Studies Show Health-Care Costs May Impact Follow-up Care After Cancer Screening

Eleven years ago this month, the scans and exams that hold the most power to spot the early signs of cancer became available for free to many American adults through the passing of the Affordable Care Act. Now, two new studies show that when those screening tests reveal potentially troubling signs, ...

gynecologic cancers

Biomarker May Help to Predict Response to Gemcitabine for Patients With High-Grade Serous Ovarian Cancer

For more than 2 decades, the chemotherapy agent gemcitabine has been a mainstay treatment for several types of cancer. Now, scientists have uncovered genetic evidence of which patients with high-grade serous ovarian cancer are likely to benefit from the drug. In a study published by Panagiotis...

breast cancer
survivorship

Active Living After Cancer Program May Improve Physical Functioning for Breast Cancer Survivors

Breast cancer survivors who participated in Active Living After Cancer, an evidence-based 12-week group program, markedly increased their physical activity and ability to accomplish the basic pursuits of daily life, reported Tami-Maury et al in the journal Cancer. The results show the program could ...

The Wistar Institute Recruits Vaccine Researcher Amelia Escolano, PhD, and Immunologist Nan Zhang, PhD, as Assistant Professors

The Wistar Institute, an international biomedical research leader in cancer, immunology, and infectious diseases, has appointed Amelia Escolano, PhD, and Nan Zhang, PhD, as Assistant Professors. Dr. Escolano’s research focuses on the development of novel vaccine approaches against highly mutating ...

hematologic malignancies
global cancer care

Paradox Between Cost and Hematopoietic Cell Transplant Rate in Latin America

In this installment of The ASCO Post’s Global Oncology series, Guest Editor Chandrakanth Are, MBBS, MBA, FRCS, FACS, spoke with Gregorio Jaimovich, MD, Director of the Bone Marrow Transplant Program at Favaloro University Hospital in Buenos Aires. Distinguished expert on radiation therapy and bone...

gastrointestinal cancer
global cancer care

Gastrointestinal Oncologist Katherine Van Loon, MD, MPH: A Pioneer in Global Oncology

Katherine Van Loon, MD, MPH, was raised in Miami, until the age of 12, and then her family relocated to Atlanta, where she spent her junior and high school years. “If you ask my parents about my decision to become a doctor, they will say I first declared it at age 5. Nobody knew how that idea came...

breast cancer

Minnesota Senator Amy Klobuchar Announces Breast Cancer Diagnosis

On September 10, 2021, Senator Amy Klobuchar (D-MN) released the following statement: “I wanted to share an update about my health. In February of this year, doctors at Mayo Clinic found small white spots called calcifications during a routine mammogram. After this was discovered, I had a biopsy...

solid tumors
hematologic malignancies

ASCO 2021: Roundup of Studies You May Have Missed

As ASCO Annual Meeting attendees know by now, clinicians don’t have to be at McCormick Place to hear practice-changing findings and forward-looking advances in the field of oncology. Interesting content was no exception at the 2021 conference, so in addition to covering the biggest news from the...

immunotherapy
lymphoma

Lymphoid Malignancies: What’s Next for Antibody-Drug Conjugates?

Antibody-drug conjugates are improving outcomes of patients with lymphoma, often those who have exhausted treatment options after chimeric antigen receptor (CAR) T-cell therapy. Four available antibody-drug conjugates are in the clinic, with brentuximab vedotin moving into the front-line...

Expert Point of View: Elena Élez, MD, PhD

Invited discussant of the two studies, Elena Élez, MD, PhD, of the Colon Cancer Program, Vall d’Hebron Institute of Oncology, Barcelona, Spain, discussed the challenge of treating BRAF-mutant colorectal cancer and what the new data bring to that effort. Dr. Élez noted: “BRAF V600E–mutant metastatic ...

covid-19

FDA Authorizes Booster Dose of Pfizer-BioNTech COVID-19 Vaccine for Certain Populations

The U.S. Food and Drug Administration (FDA) has amended the emergency use authorization (EUA) for the Pfizer-BioNTech COVID-19 vaccine to allow for the use of a single booster dose to be administered at least 6 months after completion of the primary series in individuals aged 65 years and older;...

issues in oncology

Integrating Community-Based Interventions Into Cancer Care for Low-Income and Minority Patients May Improve Quality of Life, Reduce Care Disparities

It has been well documented that a confluence of many factors, including low-socioeconomic status, contribute to health disparities and worse outcomes in minority patients with cancer. Strategies that partnered community-based health workers with low-income and minority patients with cancer...

issues in oncology
supportive care
global cancer care

Study Examines How Children Cope With a Parent’s Cancer Diagnosis

A cancer diagnosis can abruptly and durably alter the course of daily life—not just for the person diagnosed but also for family members. New research presented by Sinen Korbi, MD, and colleagues at the European Society for Medical Oncology (ESMO) Congress 2021 examined the coping mechanisms of...

Strict Adherence to Algorithm Required

According to the investigators, the SENTOR trial suggests that sentinel lymph node biopsy should be considered for the surgical staging of apparent clinical stage I endometrial cancer with no evidence of extrauterine disease on imaging or intraoperative survey.1 “If [sentinel lymph node biopsy] is...

issues in oncology
palliative care

Improving End-of-Life Discussions With Patients Who Have Advanced Cancer

Although studies have shown that patients with advanced cancer want their oncologists to discuss their advance care plans with them, fewer than half of those patients have that conversation. The reasons are many, including the difficulty many oncologists have in initiating conversations about...

Cellular Therapy Pioneer Renier Brentjens, MD, PhD, Joins Roswell Park as Deputy Director and Chair of Medicine

A leader in the field of cancer immunotherapy has returned to his Western New York roots to take on leadership roles in both research and clinical care at Roswell Park Comprehensive Cancer Center. Renier Brentjens, MD, PhD, has joined Roswell Park as Deputy Director, The Katherine Anne Gioia...

gastroesophageal cancer

Reduced-Intensity Chemotherapy for Older, Frail Patients With Advanced Gastroesophageal Cancer

Patients who had advanced gastroesophageal cancer but were considered unsuitable for full-dose chemotherapy because of their advanced age and/or frailty “had an improved patient experience with no significant detriment in cancer control” when treated with reduced-intensity chemotherapy in the phase ...

An Oncologist’s Prescription: Humanity and Love

Cancer care is one of the most technical and scientific of all medical disciplines. Oncologists must keep abreast of a dizzying array of novel treatment options coming out of the laboratory while delivering empathetic care for the physical and emotional needs of their patients with cancer....

Dana-Farber Cancer Institute Establishes the David Liposarcoma Research Initiative

Dana-Farber Cancer Institute announced that The Rossy Foundation has committed $10 million to establish the David Liposarcoma Research Initiative. The 5-year initiative will conduct groundbreaking research into liposarcoma at Dana-Farber and external collaborating partner institutions, with the aim ...

covid-19

Teleoncology for Veterans With Cancer During the COVID-19 Pandemic

In a single-center study reported in JCO Oncology Practice, Jiang et al found an overall high level of satisfaction with teleoncology care during the COVID-19 pandemic among veterans with cancer in the United States, although a preference for in-person visits was commonly expressed. Teleoncology...

Gastrointestinal Oncologist Focuses on Both the Art and Science of Treating Patients With Cancer

Chloe Atreya, MD, PhD, was born and reared in Ann Arbor, Michigan. Her mother is a poet, and her father is a planetary physicist and a professor at the University of Michigan. “Some of my early memories that influenced my decision to go into medicine stem from conversations I had with my father...

prostate cancer

Prostate Cancer Diagnostics: Novel Approaches Are Leaving Conventional Imaging Behind

Advances in molecular imaging are having a big impact on prostate cancer management and outcomes, according to Ashesh B. Jani, MD, the James C. Kennedy Professor in Prostate Cancer, Department of Radiation Oncology at the Winship Cancer Institute of Emory University, Atlanta. Dr. Jani described his ...

issues in oncology
survivorship

Two Studies Explore the Role of Primary Care Providers in Effective Cancer Care

Communication between patients and their primary care providers is key to ensuring effective cancer care, both before diagnosis and after treatment, according to two recent papers authored by University of Michigan Rogel Cancer Center researchers. Although each study analyzed different stages of...

pain management

Study Finds Evidence-Based Interventions Added to Screening Did Not Improve Cancer Pain

When added to regular screening and guidelines, evidence-based interventions implemented at the patient, health professional, and service levels did not significantly improve cancer pain, according to research led by Melanie Lovell, MBBS, PhD, Medical Head of Palliative Care at HammondCare and...

covid-19

FDA Grants Approval to the Pfizer-BioNTech COVID-19 Vaccine

On August 23, the U.S. Food and Drug Administration (FDA) approved the first COVID-19 vaccine. The vaccine has been known as the Pfizer-BioNTech COVID-19 vaccine, and will now be marketed as Comirnaty, for the prevention of COVID-19 disease in individuals aged 16 years and older. The vaccine also...

integrative oncology

Gut Microbiome and Cancer

In recent years, the gut microbiome has garnered considerable attention as a scientific field, with far-reaching potential for clinical good. The trillions of microorganisms that inhabit the digestive tract form an incredibly complex community, which participates in countless interactions with its...

issues in oncology

The Patient We See and the Person We May Not

A middle-aged patient was referred to our clinic with a mass in his liver. It had been detected the preceding year, and the patient underwent a battery of investigations with scans and biopsies to reach a diagnosis of metastatic lesion of the liver. After appropriate consultations with oncologists, ...

AMA, Satcher Health Leadership Institute Announce Inaugural Recipients of Health Equity Advocacy Fellowship

The American Medical Association (AMA) and the Satcher Health Leadership Institute at the Morehouse School of Medicine recently announced the selection of 12 physicians as the inaugural group of fellows for the Medical Justice in Advocacy Fellowship. This new collaborative initiative is intended to ...

global cancer care

An Egyptian Surgical Oncologist Urges Global Cooperation to Achieve Equitable Cancer Care

In this installment of The ASCO Post’s Global Oncology series, Guest Editor Chandrakanth Are, MBBS, MBA, FRCS, FACS, spoke with Ashraf Zaghloul, MD, DrPH, Professor at the National Cancer Institute of Egypt and President of the Egyptian Society of Surgical Oncology. Dr. Zaghloul was born in 1956 in ...

breast cancer

Study Explores Rates of Reconstruction for Women With Inflammatory Breast Cancer Undergoing Mastectomy

The percentage of patients with inflammatory breast cancer who select reconstructive surgery after mastectomy—whether immediate or delayed—remains low in spite of improvements in treatment and long-term survival, but the numbers are increasing, according to recent research published by Karadsheh et ...

Oncology Community Mourns the Loss of Investigator Angelo Di Leo, MD, PhD

Oncologist Angelo Di Leo, MD, PhD, recently died after a long struggle with neurodegenerative disease. He was 58 years old. Dr. Di Leo was devoted to breast cancer research for more than 25 years. He first trained with Gianni Bonadonna, MD, in Milan, followed by postdoctoral research at Jules...

issues in oncology

Bridging the Gender Gap in Oncology

Women account for a growing proportion of the oncology workforce. Multiple studies, however, show that women oncologists are underrepresented in leadership positions, may have significantly lower salaries than men, and may be subjected to discriminatory practices stimulated by a medical culture...

leukemia

Being Both a Cancer Provider and a Cancer Survivor Is a Rare Privilege

Perhaps my 35-year career as a surgical oncologist and researcher specializing in soft-tissue sarcomas should have prepared me to recognize the signs of chronic lymphocytic leukemia (CLL) when they first appeared a few days before Christmas in 2016, but it did not. In fact, my symptoms were so...

global cancer care

Predicting Global Cancer Trends in 2021

Although we are just halfway through 2021, the outlook for improvements in global cancer trends looks grim. According to new estimates by the International Agency for Research on Cancer’s Global Cancer Observatory, the global cancer burden rose to 19.3 million cases and 10 million deaths in 2020...

gynecologic cancers
global cancer care

New Recommendations From WHO and HRP for the Screening and Treatment of Cervical Cancer

The World Health Organization (WHO) and the Human Reproduction Programme (HRP)—the main instrument within the United Nations system for research in human reproduction—have launched a new guideline to help countries make faster progress, more equitably, in the screening and treatment of cervical...

supportive care

How to Talk With Teens and Young Adults About Their End-of-Life Goals

Although death rates for adolescent and young adults (AYAs) with cancer have been dropping 0.8% a year from 2009 to 2018, cancer remains a leading disease-related cause of death among this patient population. This year, the National Cancer Institute (NCI) estimates that 88,260 AYAs, defined by the...

issues in oncology
survivorship

Addressing Sexuality Challenges Throughout the Cancer Care Continuum

Multiple studies have shown that sexuality and intimacy problems are common among patients with cancer, often beginning at the time of diagnosis and persisting through the continuum of care into the survivorship setting. Although these problems have been well documented, many patients and survivors ...

geriatric oncology

Do Community Oncologists Have Access to Geriatric Specialty Care for Older Patients?

As our population rapidly ages, the burden of cancer incidence increases accordingly, creating an urgent need for greater and more incisive research on the diagnosis, treatment, and survivorship issues for older adults with cancer. Given the numerous challenges faced by today’s busy oncologists, a...

Whispers Over My Shoulder

When I interviewed for my current post as a first-time consultant in medical oncology in the United Kingdom, I was asked about my 5-year career plan. I remember some detail of my reply, but I don’t think it even remotely encompassed the depth of insight I would gain from the patients I’ve treated...

Mary Daly, MD, PhD, FACP, Receives NCCN’s 2021 Rodger Winn Award

The National Comprehensive Cancer Network (NCCN) recently presented Mary B. Daly, MD, PhD, FACP, Professor in the Department of Clinical Genetics and Director of the Risk Assessment Program at Fox Chase Cancer Center, with the Rodger Winn Award. The Rodger Winn Award is given annually to one NCCN...

covid-19

Navigating the Post-Vaccine Pandemic

By now, most health-care workers have been vaccinated against COVID-19.* Physical immunity would appear to last for at least 6 months and probably longer. The physical pandemic for most oncologists is declining, with an end in sight. We are protected from the serious physical consequences of...

The Ohio State Recruits Marcos J. de Lima, MD, to Lead Blood and Marrow Transplant and Cellular Therapy Programs

The Ohio State University Comprehensive Cancer Center–Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) has recruited Marcos J. de Lima, MD, to lead its Blood and Marrow Transplant and Cellular Therapy programs, two key leadership positions within central...

health-care policy

How the Biden Administration Is Changing Oncology Care

A change in presidential administrations has implications across the health sector, including for oncology. In this column, we review some recent actions by Congress and the Biden administration and their implications for the oncology community. We focus on three areas: funding for patients and...

gynecologic cancers
pancreatic cancer

Electronic Olfaction System Under Study as Screening Tool for Pancreatic and Ovarian Cancers

An odor-based test that detects vapors emanating from blood samples was able to distinguish between benign and pancreatic and ovarian cancer cells with up to 95% accuracy, according to a new study presented by Johnson et al during the 2021 ASCO Annual Meeting (Abstract 5544). The findings suggest...

palliative care

The Daughter of a Fighter Pilot Becomes a Leader in Compassionate Cancer Care

Jamie H. Von Roenn, MD, FASCO, grew up in the suburbs of Chicago as the middle child of three girls. She was, by her own account, extremely shy by nature. Her mother was a graduate of the University of Chicago, but her father’s college education was preempted by his service as a fighter pilot in...

Working on the Night Shift, a Connection to a Patient With Cancer Inspires a Career

Jaap Verweij, MD, PhD, FASCO, was born in 1953 in Velsen, a municipality situated on both sides of the massive North Sea Canal in the Netherlands. His father was a sea captain, and other close family members also plied the oceans for a living in the fishing or transport industries. Dr. Verweij...

head and neck cancer

A Pioneer in Head and Neck Cancer Surgery Whose Career Was Founded on Passion and Dedication

The term “head and neck surgery” had little meaning until the 1940s, when it was used by groundbreaking surgeon Hayes Martin, MD, in one of his publications. Dr. Martin was then Chief of Head and Neck Services at Memorial Hospital, later renamed Memorial Sloan Kettering Cancer Center (MSK), where...

cardio-oncology

A Career in Cardio-oncology Founded on Simple Principles Taught by Her Immigrant Parents

Cardio-oncology focuses on the detection, monitoring, and treatment of cardiovascular disease occurring secondary to cancer treatment, and the mechanistic and epidemiologic intersection between cardiovascular disease and cancer. With the advent of targeted agents and immunotherapies,...

lung cancer

Serendipity Plays a Role in a Journey to a Noted Career in Surgical Oncology

Over the past 2 decades, the oncologic mantra “early detection leads to cure” has taken on special meaning in lung cancer, persistently a leading cause of cancer death in the United States. “Over a 25-year period, we’ve seen a revolution in early detection, understanding of tumor biology, and...

A Brooklyn Girl Bucks Her Old-Fashioned Upbringing to Become a Leader in Bone Marrow Transplantation

In the face of old school mores, self-motivation and perseverance were needed to build a career as a nationally regarded blood and bone marrow transplant expert. “I was born and reared in Brooklyn, New York, the oldest of seven children of Irish-Italian parents who did not espouse professional...

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