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Breast Cancer
COVID-19

Trends in Breast Cancer Diagnoses During the COVID-19 Pandemic

Investigators may have identified a decrease in newly diagnosed breast cancer cases during the first year of the COVID-19 pandemic, according to a recent study published by Fefferman et al in Cancer Medicine. The findings highlight that breast cancer was not immune to pandemic-related stressors and ...

Issues in Oncology
COVID-19

HPV Vaccination Among Young Adults Prior to and During the COVID-19 Pandemic

In a study reported in JAMA Network Open, Sonawane et al found that no increase in human papillomavirus (HPV) vaccination rates among young adults was observed during the COVID-19 pandemic in the United States, contrary to the increased rates observed prior to the pandemic. Study Details The study...

Leukemia
Lymphoma
COVID-19

COVID-19 Risk in Pediatric Patients Receiving Treatment for Acute Lymphoblastic Leukemia or Lymphoma

In a retrospective case series reported in JAMA Network Open, Hashmi et al found that more than one-third of pediatric patients receiving treatment for newly diagnosed acute lymphoblastic leukemia/lymphoblastic lymphoma (ALL/LL) developed COVID-19 infection during a recent 2-year period. Study...

COVID-19

Annual Report to the Nation, Part 2: New Cancer Diagnoses Fell Abruptly Early in the COVID-19 Pandemic

New diagnoses of six major cancer types in the United States fell abruptly in early 2020, coinciding with the start of the COVID-19 pandemic, according to findings from part 2 of the latest Annual Report to the Nation on the Status of Cancer.1 The volume of pathology reports also declined sharply...

COVID-19

Annual Report to the Nation on COVID-19’s Impact on Cancer Diagnosis Finds Sharp Declines in New Diagnoses of Six Major Cancers

Findings from the Annual Report to theNation on the Status of Cancer, Part 2: Early Assessment of the COVID-19 Pandemic’s Impact on Cancer Diagnosis show new diagnoses of six major cancer types in the United States fell sharply between March and May 2020, coinciding with the beginning of the...

Issues in Oncology
COVID-19

Annual Report to the Nation on the Status of Cancer, Part 2, Focuses on COVID-19’s Impact on Cancer Diagnoses

The Annual Report to the Nation on the Status of Cancer, Part 2—published by Negoita et al in the journal Cancer—showed that new diagnoses of six major cancer types in the United States fell sharply between March and May of 2020, coinciding with the beginning of the COVID-19 pandemic. The six...

Breast Cancer
Gastrointestinal Cancer
Supportive Care
COVID-19

Updates on Cancer Therapies Under Study From 2023 ASCO Breakthrough

Presented here are some brief summaries of novel therapies under study from the 2023 ASCO Breakthrough meeting in Yokohama, Japan. The subjects range from new observations about a HER2-directed bispecific antibody and systemic treatment of gastric cancer to an option for treating hand-foot syndrome ...

Solid Tumors
COVID-19

Early-Stage Cancer Diagnoses in the United States May Have Decreased During the First Year of the COVID-19 Pandemic

Investigators have found that monthly U.S. adult cancer diagnoses decreased by 50% early in April 2020 and that the largest decreases were observed for stage I tumors, resulting in a higher proportion of late-stage cancer diagnoses, according to a recent study published by Han et al in The Lancet...

Solid Tumors
COVID-19

Vaccine Rollout May Reduce COVID-19–Related Mortality by 84% Among Patients With Cancer, Study Predicts

The rollout of COVID-19 vaccines may be an effective strategy for reducing COVID-19–related hospitalizations and mortality in patients with cancer, according to a recent study published by Starkey et al in Scientific Reports. Study Methods and Results In this study, investigators analyzed the...

Lymphoma
COVID-19

COVID-19 Booster Doses May Strengthen Immunity in Patients With Lymphoma

Researchers have found that repeated COVID-19 vaccination may increase the vaccine’s effectiveness at preventing the infections in patients with lymphoma, particularly after four doses, according to a new study published by Wijaya et al in The Lancet. Background Patients with lymphoma often have...

COVID-19

Certain Cancers Will Likely Rise Exponentially Because of COVID-19 Screening Delays, Study Predicts

Delays in cancer screening during the COVID-19 pandemic will likely cause a significant increase in cancer cases that could have been caught earlier with screening. These cases may now be diagnosed at later stages, placing an increased burden on an already-strained health-care system, according to...

leukemia
covid-19

Jennifer A. Woyach, MD, on New Findings on CLL, COVID-19, and Treatment With Obinutuzumab Plus Venetoclax

Jennifer A. Woyach, MD, of The Ohio State University Comprehensive Cancer Center, discusses results of a phase III study showing that progression-free survival with ibrutinib plus obinutuzumab plus venetoclax is not superior to ibrutinib plus obinutuzumab for treatment-naive older patients with chronic lymphocytic leukemia (CLL) in the setting of the COVID-19 pandemic. Long-term follow-up will determine whether there are advantages to obinutuzumab plus venetoclax, with special attention to measurable residual disease and therapy discontinuation (Abstract 7500).

Colorectal Cancer
Lung Cancer
Breast Cancer
COVID-19

Incidence of Colorectal, Lung, and Breast Cancers May Be Rising Due to COVID-19–Related Screening Delays

Delays in cancer screenings during the COVID-19 pandemic may have resulted in lower reported incidences of colorectal, lung, and breast cancers, reflecting potentially high rates of undiagnosed cancer and later-stage diagnoses, according to a new study published by Romatoski et al in the Journal of ...

COVID-19

American College of Surgeons Evaluates the Impact of COVID-19 Pandemic on National Cancer Database Reporting

New research from the American College of Surgeons (ACS) outlines significant ways that the COVID-19 pandemic destabilized usual patterns of cancer care, as reported in the National Cancer Database (NCDB). The NCDB is one of the largest cancer registries in the world and is used by thousands of...

COVID-19

Multisystem Inflammatory Syndrome in Children With Cancer and COVID-19

In a U.S. cohort study reported in JAMA Oncology, Martin et al described the clinical course and potential factors associated with post–COVID-19 multisystem inflammatory syndrome in children with cancer also infected with COVID-19. Post–COVID-19 multisystem inflammatory syndrome is a...

Solid Tumors
Supportive Care
COVID-19

Patients With Cancer May Prefer Telemedicine Appointments Over In-Person Visits When Both Are Available

Investigators have found that telemedicine may consistently outperform in-person visits for cancer care when assessed for access to care, provider response, and patient experience, according to a new study published by Patel et al in JNCCN–Journal of the National Comprehensive Cancer Network....

COVID-19
Breast Cancer
Colorectal Cancer

Lifestyle Habits, Risk Factors, and Cancer Screening During COVID-19 Pandemic

Investigators discovered both favorable and unfavorable changes in major cancer risk factors, preventive behaviors and services, and screenings in the United States during the COVID-19 pandemic, according to a new study published by Star et al in Cancer Epidemiology, Biomarkers & Prevention....

Issues in Oncology
COVID-19

E-Cigarette Use Increased Significantly Among Younger U.S. Adults Between 2019 and 2021

Almost 750,000 more adults in the United States, aged 18 to 29 years, may have used e-cigarettes during the period that spanned the e-cigarette or vaping-product use–associated lung injury outbreak and COVID-19 pandemic from 2019 to 2021, according to a new study published by Bandi et al in the...

COVID-19
Issues in Oncology

COVID-19 Pandemic May Have Disrupted Cancer Reporting in 2020 and Beyond

Investigators have uncovered factors contributing to the COVID-19 pandemic’s destabilization of the usual patterns of cancer care, described specific ways that National Cancer Database data models were impacted by the pandemic, and offered guidance to cancer centers across the United States on how...

COVID-19
Issues in Oncology

New Study Examines Cancer-Related Mortality Rates During First Year of COVID-19 Pandemic

U.S. mortality rates with cancer as the underlying or primary cause decreased during the first year of the COVID-19 pandemic, whereas mortality rates with cancer as a contributing cause increased, according to a new study published by Zhao et al in JCO Oncology Practice. The findings demonstrated...

Issues in Oncology
COVID-19

Trust in Cancer Information May Have Declined Among Black Individuals During COVID-19 Pandemic

Investigators have found that Black individuals’ trust in information provided by the government on cancer fell by almost 50% during the COVID-19 pandemic, according to a new study published by Bispo et al in the Journal of Health Communication. The investigators stressed the need to assess whether ...

COVID-19
Issues in Oncology

COVID-19 Vaccination Rates May Be Lower in Patients With Cancer Who Have Comorbidities, Certain Types of Cancer, and Specific Sociodemographic Factors

Investigators have found that patients undergoing treatment for cancer who have comorbidities, metastatic solid or non–B-cell hematologic malignancies, and those living in areas with lower levels of education and higher levels of unemployment may have lower rates of COVID-19 vaccination, according...

COVID-19

European OnCovid Registry Analysis of COVID-19 Sequelae During Omicron Phase vs Earlier Phases in Patients With Cancer

In an analysis from the European OnCovid registry reported in The Lancet Oncology, Alessio Cortellini, PhD, and colleagues found that rates of COVID-19 sequelae among patients with cancer were lower during the omicron phase of the pandemic vs the alpha-delta and prevaccination phases, consistent...

Issues in Oncology
COVID-19

Study Finds Cancer Screening in the United States Lagged During the Second Year of the COVID-19 Pandemic

In a study reported in the Journal of Clinical Oncology, Star et al found that cancer screening remained below prepandemic levels in the United States during the second year of the COVID-19 pandemic. Study Details Data on past-year receipt of age-eligible screening for breast cancer (women aged 50...

COVID-19

Millions of U.S. Individuals May Have Missed Cancer Screenings During Second Year of COVID-19 Pandemic

Investigators have found that millions of individuals in the United States continued to miss critical cancer screening tests during the second year of the COVID-19 pandemic, according to a new study published by Star et al in the Journal of Clinical Oncology. Compared with 2019 levels, individuals...

COVID-19

New Study Highlights Impact of COVID-19 Pandemic on Cancer Screening Delays

Investigators have found further evidence to quantify the vast, lingering impact of the global COVID-19 pandemic on timely cancer screening—highlighting the urgent need for health-care providers to address significant delays to cancer screenings in populations most likely to delay testing,...

COVID-19

Half of Patients With Cancer May Develop Long COVID, With Risk Higher in Female Patients

More than one in two patients with cancer may experience symptoms of long COVID for more than 6 months after initial COVID-19 infection, according to a new study published by Dagher et al in eLife. The findings were comparable to the reported incidence of long COVID in the general population, but...

Breast Cancer
COVID-19

COVID-19 Outcomes Across Pandemic Phases in European Patients With Breast Cancer

In a study using data from the European OnCovid registry reported in the Journal of Clinical Oncology, Tagliamento et al found that the severity of COVID-19 infection in patients with breast cancer decreased during the Omicron variant phase of the pandemic. In addition, a full vaccine course...

COVID-19
Issues in Oncology

How Telemedicine Can Transform Clinical Research and Practice

The COVID-19 pandemic transformed the world, and nowhere more so than in the health-care arena. Significant changes happened almost overnight in the delivery of medical care to focus on the safety and convenience of patients, staff, and providers. Although pilot efforts to integrate telemedicine...

Hematologic Malignancies
Cost of Care
Survivorship
COVID-19

Financial Burden for Blood or Marrow Transplantation Survivors During the COVID-19 Pandemic

In an analysis from the BMT Survivor Study (BMTSS) reported in the Journal of Clinical Oncology, Smita Bhatia, MD, MPH, and colleagues found that survivors of blood or marrow transplantation (BMT) were more likely to have high out-of-pocket medical costs vs comparator siblings during the COVID-19...

COVID-19
Palliative Care

Potential Impact of the COVID-19 Pandemic on Place of Death Among Medicaid-Insured and Commercially Insured Patients With Cancer in Washington State

In a study reported in the Journal of Clinical Oncology, Panattoni et al found that patients dying from cancer located in Washington State who were insured by Medicaid were more likely to die at home without hospice services during the COVID-19 pandemic than those with commercial insurance. Study...

Breast Cancer
Gynecologic Cancers
Colorectal Cancer
COVID-19

Breast, Cervical, and Colorectal Cancer Screening Rates Before vs After the COVID-19 Pandemic

In a U.S. cross-sectional study reported in JAMA Oncology, Oakes et al found that as of December 2021, breast, cervical, and colorectal cancer screening rates remained below pre–COVID-19 pandemic levels, despite initial rebounds in some rates. Reduced screening rates were accompanied by reduced...

COVID-19
Immunotherapy

Effect of Baseline Immunosuppression on COVID-19 Severity and Risk of Cytokine Storm in Patients Receiving Immunotherapy for Cancer

In a registry-based retrospective cohort study reported in JAMA Oncology, Ziad Bakouny, MD, and colleagues in the COVID-19 and Cancer Consortium (CCC19 registry) found that patients receiving cancer immunotherapy who had baseline immunosuppression, but not those without baseline immunosuppression,...

Immunotherapy
COVID-19

Can Patients With Cancer Treated With Immunotherapy Safely Receive mRNA COVID-19 Vaccines?

New research confirmed the safety of mRNA COVID-19 vaccines in individuals with cancer who are undergoing immunotherapy, according to a novel study published by Widman et al in JNCCN–Journal of the National Comprehensive Cancer Network. The researchers analyzed the frequency of immune-related...

Issues in Oncology
COVID-19

Effect of Goals-of-Care Program for Inpatients at a Comprehensive Cancer Center During the COVID-19 Pandemic

As reported in the Journal of Clinical Oncology by David Hui, MD, MSc, and colleagues, an interdisciplinary goals-of-care program instituted at The University of Texas MD Anderson Cancer Center in response to anticipated COVID-19–related increases in need for intensive care unit (ICU) use resulted ...

COVID-19

Deaths Attributed to Both Cancer and COVID-19 in the United States: March to December 2020

In a research letter published in JAMA Oncology, Xuesong Han, PhD, and colleagues identified the number of deaths attributable to both cancer and COVID-19, with either as an underlying or contributing cause, in the United States from March 1 to December 31, 2020, and analyzed risk factors for these ...

COVID-19

Study Examines Potential Benefits of a Fourth COVID-19 Vaccination for Patients With Cancer

A research team led by Matthias Preusser, MD, PhD, Professor of Medical Oncology and Head of the Clinical Division of Oncology at the Medical University of Vienna, had already demonstrated that patients with cancer may benefit from a third vaccination to protect them against COVID-19. A recent...

COVID-19

Antibody Response to Three-Dose COVID-19 mRNA-1273 Vaccination Schedule in Immunocompromised Patients With Hematologic Cancers

In a Dutch prospective observational cohort study reported in JAMA Oncology, Haggenburg et al found that a third dose of the COVID-19 mRNA-1273 vaccine increased antibody levels in immunocompromised patients with hematologic cancers overall to levels comparable to those observed in healthy controls ...

COVID-19
Survivorship

How Did the First Year of the COVID-19 Pandemic Affect Cancer Survivors?

Recent research published by Xuesong Han, PhD, and colleagues in the journal Cancer indicated that during the first year of the COVID-19 pandemic, the proportion of working-aged U.S. adults without health insurance did not change despite increases in unemployment. The prevalence of unhealthy...

COVID-19
Issues in Oncology

Fewer People Tried to Quit Smoking During COVID-19 Pandemic, Study Shows

A new study led by researchers at the American Cancer Society (ACS), shows serious smoking cessation activity declined among adults in the United States immediately after the onset of the COVID-19 pandemic and persisted for more than a year. Declines in attempts to quit smoking were largest among...

Supportive Care
COVID-19

Clinical Practice Guidelines for Treatment and Prophylaxis of VTE in Patients With Cancer, Including Those Infected With COVID-19

In an article published in The Lancet Oncology, Farge et al outlined the International Initiative on Thrombosis and Cancer (ITAC) 2022 clinical practice guidelines for the treatment and prophylaxis of venous thromboembolism (VTE) in patients with cancer, including those infected with COVID-19. The...

COVID-19

FDA Authorizes Emergency Use of Novavax COVID-19 Vaccine, Adjuvanted

On July 13, the U.S. Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for the Novavax COVID-19 vaccine, adjuvanted, for the prevention of COVID-19 caused by SARS–CoV-2 in individuals aged 18 years and older.  “Authorizing an additional COVID-19 vaccine expands the...

Global Cancer Care
COVID-19

Study Reveals Cancer Screening Decreased Worldwide During Height of COVID-19 Pandemic

A study that surveyed cancer screening data included in medical journals worldwide from January 2020 into December 2021 showed significant decreases in the number of screenings for breast, colorectal, and cervical cancers during the early phase of the COVID-19 pandemic. The findings of the study,...

Lung Cancer
COVID-19

Antibody Response to SARS–CoV-2 Wild-Type Virus and Variants After mRNA Vaccination in Patients With NSCLC

In a single-institution study reported in the Journal of Clinical Oncology, Valanparambil et al found that one-quarter of patients with non–small cell lung cancer (NSCLC) had poor antibody responses to the SARS–CoV-2 wild-type (WT) strain after mRNA vaccination, and that neutralizing antibody...

COVID-19

Outcomes of the SARS–CoV-2 Omicron Variant Outbreak Among European Patients With Cancer

In an analysis from the retrospective OnCovid registry study reported in The Lancet Oncology, David J. Pinato, PhD, and colleagues detailed outcomes of the SARS­–CoV-2 omicron variant outbreak among European patients with cancer. Study Details The analysis included 3,473 patients with cancer from...

Lung Cancer
Immunotherapy
COVID-19

Study Finds COVID-19 Vaccines Are Safe for Patients Treated With Immune Checkpoint Inhibitors for Lung Cancer

Patients with cancer have received priority status to receive COVID-19 vaccinations, but limited data are available regarding the safety and efficacy of the vaccines for patients treated with immune checkpoint inhibitors for lung cancer. Now, a new study published by Hibino et al in the Journal of...

COVID-19
Colorectal Cancer
Survivorship
Genomics/Genetics

American Cancer Society Investigators Present Studies on COVID-19 Pandemic, Racial/Ethnic Disparities, and Coverage for Genomic Testing

Investigators at the American Cancer Society presented results of several studies during poster sessions at the 2022 ASCO Annual Meeting. Summaries of a few of these studies are provided here. COVID-19 and Cancer Mortality According to a new study led by researchers at the American Cancer Society,...

COVID-19

Looking Back at Telemedicine During the COVID-19 Era: Lessons Learned and Disparities Identified

Telemedicine stepped up to the plate when the COVID-19 pandemic swept the globe. Oncology providers—and practitioners in all specialties—had to rapidly adapt to a telemedicine format when face-to-face visits were severely limited. This scenario had its benefits for both patients and providers (and...

COVID-19

FDA Authorizes Moderna and Pfizer-BioNTech COVID-19 Vaccines for Children as Young as 6 Months of Age

On June 17, the U.S. Food and Drug Administration (FDA) authorized emergency use of the Moderna COVID-19 vaccine and the Pfizer-BioNTech COVID-19 vaccine for the prevention of COVID-19 to include use in children as young as 6 months of age.  For the Moderna vaccine, the FDA amended the emergency...

covid-19

Jenny S. Guadamuz, PhD, on Racial and Socioeconomic Disparities in Telemedicine Use Among U.S. Patients With Cancer During the COVID-19 Pandemic

Jenny S. Guadamuz, PhD, of Flatiron Health, discusses the use of telemedicine services in community oncology clinics for patients initiating treatments for 21 common cancers during the COVID-19 pandemic. Black, uninsured, non-urban, and less affluent patients were less likely to use telemedicine services. Although telemedicine may expand access to specialty care, the proliferation of these services may widen cancer care disparities if equitable access to these services is not ensured, according to Dr. Guadamuz (Abstract 6511).

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