Special Reports

Solid Tumors
Prostate Cancer

When Can Patients With Gleason 6 Prostate Cancer Safely Undergo Active Surveillance?

Jo Cavallo  /  July 25, 2018

Prior to ASCO’s 2016 endorsement of the Cancer Care Ontario (CCO) guideline on active surveillance in the management of localized prostate cancer,1 most men—over 90%—diagnosed with low-risk localized disease were treated with active therapy.2 Today, about 50% of American men with low-risk disease ...

Breast Cancer

Improving Care for Women With Late-Stage Breast Cancer

Jo Cavallo  /  June 25, 2020

The global toll of breast cancer on women is staggering. In 2018, nearly two million new breast cancer cases were diagnosed, an increase of more than 20% since 2008,1 and mortality rates have increased by 14%, bringing the annual number of deaths worldwide from the cancer to more than 611,625.2 Alth...

Issues in Oncology
Cost of Care

Weighing the Cost and Value of CAR T-Cell Therapy

Jo Cavallo  /  May 25, 2018

This past year’s approval by the U.S. Food and Drug Administration (FDA) of two chimeric antigen receptor (CAR) T-cell therapies heralded a new era in both effective cancer treatments and the most expensive cancer drugs ever. Tisagenlecleucel (Kymriah) was initially approved for the treatment of r...

Breast Cancer

When Is Active Surveillance Appropriate in the Treatment of DCIS?

Jo Cavallo  /  March 25, 2018

In 2017, more than 63,000 women in the United States were diagnosed with in situ breast cancer. The overwhelming majority of those women, about 83%, were diagnosed with ductal carcinoma in situ (DCIS), a condition characterized by the presence of abnormal cells confined to the breast milk ducts; a...

Issues in Oncology
Supportive Care

Findings From ASCO’s Second National Cancer Opinion Survey

Jo Cavallo  /  January 25, 2019

Despite a recent study showing that patients with cancer who chose alternative therapies over conventional cancer treatment have a higher risk of death, nearly 4 in 10 Americans believe cancer can be cured by alternative remedies alone, according to the results of ASCO’s 2018 National Cancer Opinion...

Supportive Care
Lung Cancer

Providing a Safe Haven for Patients With Advanced Lung Cancer

Jo Cavallo  /  December 25, 2017

In 1996, Jimmie C. Holland, MD, the Wayne E. Chapman Chair in Psychiatric Oncology at Memorial Sloan Kettering Cancer Center (MSK) in New York, decided to launch the cancer center’s Lung Cancer Survivorship Program after she had a startling encounter with a patient. “The woman said to me, ‘Would y...

Stemming the Growing Cancer Crisis in Rural Appalachia

Jo Cavallo  /  September 25, 2017

A pair of recent studies show a troubling trend: Despite a 20% decrease in cancer mortality rates nationwide over the past 2 decades,1 Americans living in rural regions of the United States are more likely to die of cancer than persons living in metropolitan areas of the country. An analysis of canc...

Has the Promise of Precision Medicine Been Oversold?

Jo Cavallo  /  October 25, 2018

Recently, the term “personalized medicine” in oncology care has been overtaken by the more contemporary concept of “precision medicine.” According to the National Research Council of the National Academies of Science, Engineering, and Medicine, the newer terminology shifts the focus to improving p...

Supportive Care

Chronicling a Family’s History of Cancer

Jo Cavallo  /  October 25, 2017

Cancer has been an intimate part of Nancy Borowick’s life since her mother, Laurel, was diagnosed with breast cancer in 1997, when Nancy was 12. She began photographing her mother’s journey with the disease after the cancer recurred in 2009 for her final project for the Documentary Photography and...

WebMD Recognizes Seven Cancer Innovators With Its Health Heroes Award

Jo Cavallo  /  March 25, 2019

On January 15, 2019, WebMD, an online and print health-care resource for consumers, presented its 2018 Health Heroes Award in New York City to 7 people who are making a difference in oncology care. The honorees include Karen M. Winkfield, MD, PhD, Associate Professor of Radiation Oncology at Wake ...

Diary of a Storm

Jo Cavallo  /  January 25, 2018

FOR DAYS BEFORE HURRICANE HARVEY was expected to move toward Houston, Texas, on Sunday, August 27, 2017, after pummeling other cities in Texas and Louisiana, the leadership team at The University of Texas MD Anderson Cancer Center (MD Anderson) in Houston strategized on how to ensure the continuit...

Issues in Oncology

How Watson for Oncology Is Advancing Personalized Patient Care

Jo Cavallo  /  June 25, 2017

After undergoing nearly 5 years of intensive medical training, IBM’s Watson for Oncology cognitive computing system is starting to make good on its promise to accelerate personalized care for patients with cancer. The system has been trained by oncologists at Memorial Sloan Kettering Cancer Center...


Illustrating Genius

Jo Cavallo  /  December 25, 2018

FOUR AND A HALF YEARS AGO, author Neil Canavan attended a scientific conference to learn what he could about the then-emerging field of immunotherapy for cancer. After a presentation by Zelig Eshhar, PhD, principal investigator in the Department of Immunology at the Weizmann Institute of Science i...

Issues in Oncology
Cost of Care

Tackling the High Cost of Cancer Care

Jo Cavallo  /  November 25, 2017

AT THE 2017 ASCO ANNUAL MEETING, the leaders of the newly formed Value in Cancer Care Consortium (vi3c; met to discuss the group’s plan to study how to improve the affordability of cancer drugs and make them more accessible to patients. The goal of the Value in Cancer Care Consortium is ...

Issues in Oncology

Tackling the Obesity and Cancer Epidemic

Jo Cavallo  /  May 25, 2017

Research is still lacking to support a link between obesity and an increased risk of developing all types of cancer. Nevertheless, a review1 of more than 1,000 epidemiologic studies by the International Agency for Research on Cancer (IARC), a division of the World Health Organization, examining ...