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covid-19

Study Suggests Substantial Delays in Diagnosis and Treatment for Cancer During the COVID-19 Pandemic

A new study has found evidence of the adverse effects the COVID-19 pandemic had on cancer detection and surgical treatments. The study, published by Robin Yabroff, PhD, MBA, and colleagues in JNCI: The Journal of the National Cancer Institute, found a 10.2% decline in real-time electronic pathology ...

issues in oncology
gynecologic cancers

Association Between Increased BMI and Endometrial Cancer Risk in Asian Women With Postmenopausal Bleeding

The link between obesity and the risk of endometrial cancer has been well documented. A recent study, however, showed that an even lower body mass index (BMI) than previously thought may be associated with an increased risk in Asian women with postmenopausal bleeding. The findings by Liu et al were ...

Watch Now: Discussion on Eligibility Criteria and the Impact on Access to Clinical Trials

On Friday, April 9, 2021, ASCO and Friends of Cancer Research (Friends) co-hosted a live virtual event, which brought together experts from across the health-care sector to discuss the recent release of the new ASCO-Friends recommendations for modernizing eligibility criteria to improve patient...

John D. Carpten, PhD, FAACR, to Join the AACR Board of Directors

The American Association for Cancer Research (AACR) recently announced that John D. Carpten, PhD, FAACR, has been elected by the association to serve on its Board of Directors. Dr. Carpten has accepted the position previously held by Karen E. Knudsen, MBA, PhD, who is stepping down to fulfill her...

Young Urologist of the Year Award Winners

Established by Michael C. Ost, MD, MBA, the 2012–2013 American Urological Association Young Urologists Committee Chair, the Young Urologist of the Year Award is presented annually to select early-career association members in recognition of their efforts and commitment to advancing the development...

cns cancers

Reduced-Dose and Reduced-Volume Radiotherapy Plus Chemotherapy in Newly Diagnosed Patients With Average-Risk Medulloblastoma

As reported in the Journal of Clinical Oncology by Jeff M. Michalski, MBA, MD, and colleagues, the Children’s Oncology Group noninferiority phase III ACNS0331 trial has shown no decrease in event-free survival with reduced radiation boost volume in patients with newly diagnosed, average-risk...

gynecologic cancers
cost of care

Nearly Half of Surveyed Patients With Gynecologic Cancer Report Experiencing Financial Toxicity

In a new study designed to provide a more comprehensive picture of how a diverse cohort of patients with gynecologic cancer are affected by financial distress, nearly half reported financial toxicity, which was associated with economic cost-coping strategies. These findings were reported by Esselen ...

gastroesophageal cancer

Adjuvant Nivolumab Improves Disease-Free Survival vs Placebo in Resected Esophageal or Gastroesophageal Junction Cancer After Neoadjuvant Chemoradiotherapy

As reported in The New England Journal of Medicine by Ronan J. Kelly, MB BCh, MBA, of The Charles A. -Sammons Cancer Center at Baylor University Medical Center, and colleagues, an interim analysis of the phase III CheckMate 577 trial has shown a significant improvement in disease-free survival...

AUA Names 2021 Award Recipients

Each year, the American Urological Association (AUA) honors the contributions of physician researchers and educators in the field of medicine, the specialty of urology, and the organization. The following individuals are the 2021 honorees: Ian M. Thompson Jr, MD, Ramon Guiteras Award, for...

ASCO Honors 2021 Special Awards Recipients

Researchers, patient advocates, and global oncology leaders who have worked to reshape cancer care around the world are among the recipients of ASCO’s Special Awards—the Society’s highest honors—and the Women Who Conquer Cancer Mentorship Awards from Conquer Cancer, the ASCO Foundation. “The...

Fostering a Global Community of Early-Career Oncologists, Virtually

In a typical year, the new participants in ASCO and Conquer Cancer’s International Development and Education Awards (IDEA) and International Development and Education Awards–Palliative Care (IDEA-PC) program would arrive at the McCormick Place Convention Center just ahead of the ASCO Annual...

Randall F. Holcombe, MD, MBA, Named Director of UVM Cancer Center and Chief of Hematology and Oncology

The Robert Larner, MD, College of Medicine at The University of Vermont (UVM), in collaboration with the UVM Health Network and the UVM Medical Center, has announced that Randall F. Holcombe, MD, MBA, has been appointed Director of the UVM Cancer Center and Chief of the Division of Hematology and...

Karen E. Knudsen, MBA, PhD: The American Cancer Society’s First Female CEO Speaks Out

Karen E. Knudsen, MBA, PhD, of Sidney Kimmel Cancer Center at Jefferson Health, was recently appointed Chief Executive Officer of the American Cancer Society—the first female to head the organization in its 107-year history. Dr. Knudsen talks about the opportunities she sees ahead for the Society...

Kathy Giusti, MBA; Nancy Pelosi; and Charles L. Sawyers, MD, FAACR, to Receive AACR Distinguished Public Service Awards

The American Association for Cancer Research (AACR) will present Distinguished Public Service Awards to three individuals whose extraordinary work has exemplified the AACR’s mission to prevent and cure all cancers through research, education, communication, collaboration, science policy, advocacy,...

global cancer care

Incidence and Cancer-Related Mortality in Belize

Located on the northeast coast of Central America, Belize is a small, upper middle–income country bordered by Mexico, Guatemala, and the Caribbean Sea. Belize has a population of about 405,000 people (Table 1), of which about 15% are immigrants. Belize is considered to be one of the most...

health-care policy

NCCN 2021 Virtual Annual Conference

New recommendations to advance racial equity, ways to mitigate the impacts of the COVID-19 pandemic on cancer care, and ongoing strategies for preventing and controlling human papillomavirus (HPV)-associated cancers led the conversation at the National Comprehensive Cancer Network® (NCCN®) 2021...

breast cancer

Linda T. Vahdat, MD, MBA, on Triple-Negative Breast Cancer: Targeting the Tumor Microenvironment

Linda T. Vahdat, MD, MBA, of Memorial Sloan Kettering Cancer Center, discusses results of a phase II trial designed to test the concept that targeting the tumor microenvironment by depleting copper may prevent metastases, essentially disrupting the infrastructure that contributes to tumor spread.

gastroesophageal cancer
gastrointestinal cancer
immunotherapy

Adjuvant Nivolumab for Resected Esophageal or Gastroesophageal Junction Cancer After Neoadjuvant Chemoradiotherapy: CheckMate 577

As reported in The New England Journal of Medicine by Ronan J. Kelly, MBBCh, MBA, and colleagues, an interim analysis of the phase III CheckMate 577 trial has shown a significant improvement in disease-free survival with adjuvant nivolumab vs placebo in patients with resected esophageal or...

pancreatic cancer
hepatobiliary cancer
colorectal cancer
breast cancer
skin cancer
lung cancer
prostate cancer
issues in oncology

Estimated Shifts in Cancer Incidence and Death Over Next 2 Decades

In the next 2 decades, rankings of incidence and death across cancer types in the United States will undergo important changes, according to new research published by Lola Rahib, PhD, and colleagues in JAMA Network Open. The study estimates that pancreatic cancer is on course to become the...

American Cancer Society Names Karen E. Knudsen, MBA, PhD, as Its Next Chief Executive Officer

Karen E. Knudsen, MBA, PhD, will be the next Chief Executive Officer of the American Cancer Society and its advocacy affiliate, the American Cancer Society Cancer Action Network (ACS CAN), starting June 1, 2021. She will take the reins from the retiring Gary Reedy, who has served as both...

Jeff Walker, MBA, Returns to Roswell Park in Newly Created Executive Role

An experienced executive has rejoined the Roswell Park Comprehensive Cancer Center team, announced Roswell Park President and Chief Executive Officer Candace S. Johnson, PhD. Jeff Walker, MBA, has been recruited back to Western New York to fill the new role of Executive Vice President of Operations ...

William Tseng, MD, Joins Sarcoma Alliance Board of Directors

The Sarcoma Alliance recently announced the appointment of William Tseng, MD, to the organization’s Board of Directors. A surgical oncologist at Keck Medicine of the University of Southern California (USC), Dr. Tseng specializes in soft-tissue sarcoma. “Our Board of Directors comprises a...

hepatobiliary cancer
genomics/genetics

In Cholangiocarcinoma, Does Chemotherapy Response Vary According to FGFR2 Status?

With inhibitors of fibroblast growth factor receptor 2 (FGFR2) fusion and other genetic alterations now in clinical trials for cholangiocarcinoma, there is interest in better understanding what FGFR2 genetic alterations mean for patients. In particular, little is known about the effects of FGFR2...

lymphoma
immunotherapy

Challenges in Managing Hodgkin Lymphoma: Focus on Use of Brentuximab Vedotin

“I was taught that the way of progress was neither swift nor easy.” —Marie Curie To complement The ASCO Post’s continued comprehensive coverage of the 2020 American Society of Hematology (ASH) Annual Meeting & Exposition, here are two abstracts selected from the meeting proceedings focusing on...

gastrointestinal cancer

Sara Schottenstein Foundation, Dedicated to Gastric Cancer, Announces Launch

A science-focused organization dedicated to ending gastric cancer, the Sara Schottenstein Foundation recently announced its launch and its new website, http://www.saraschottensteinfoundation.org. Founded by Jeff Schottenstein, MBA, a wealth management professional in San Francisco, the Sara...

Sachin Apte, MD, MS, MBA, Joins Huntsman Cancer Institute as Chief Clinical Officer

Huntsman Cancer Institute (HCI) and University of Utah (U of U) Health announced the appointment of Sachin Apte, MD, MS, MBA, as Chief Clinical Officer of HCI and Physician-in-Chief of the cancer hospital. “Dr. Apte will lead HCI’s clinical efforts at a time when we are poised to dramatically...

Physician-Patient Relationship: Sacred and Sacrosanct

There are many relationships we build at work in our entire lifetime. Some are good, a few are not, and many are somewhere in between. But of all the relationships we are fortunate enough to build, there is no relationship more valuable and gratifying than the one between a physician and a ...

issues in oncology

Shivan J. Mehta, MD, MBA, on Preventing and Controlling HPV-Associated Cancers

Shivan J. Mehta, MD, MBA, of Abramson Cancer Center at the University of Pennsylvania, discusses how insights from behavioral economics could be harnessed to improve HPV vaccination rates, thus lowering the rate of cervical, genital, and head/neck cancers, all of which are linked to HPV.

hepatobiliary cancer

FDA Approves TheraSphere Y-90 Glass Microspheres for Unresectable Hepatocellular Carcinoma

Today, the U.S. Food and Drug Administration (FDA) approved TheraSphere Y-90 Glass Microspheres, developed for the treatment of patients with hepatocellular carcinoma. The approval expands access to this therapy, which, to date, has been utilized under a humanitarian device exemption—an FDA...

covid-19

Repurposing Available Drugs for COVID-19: An Ongoing Initiative

As of this writing, no drugs have been approved by the U.S. Food and Drug Administration (FDA) for the treatment of COVID-19, although several have received emergency use authorization and many others are being used off-label during the pandemic. In addition to searching for novel therapies, David...

prostate cancer

ASCO Guideline Update Offers Four Standards of Care for Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer

A recent ASCO guideline update, prompted by data from several phase III randomized controlled trials, summarizes the evidence supporting the best initial treatment options for the management of noncastrate advanced, recurrent, or metastatic prostate cancer. The hope is that the guideline will help...

Yale School of Medicine Announces New Section Chief of Breast Surgery

Rachel Adams Greenup, MD, MPH, FACS, has been appointed Associate Professor of Surgery (Oncology) and Section Chief of Breast Surgery for the Department of Surgery at Yale School of Medicine. In her new role, Dr. Greenup will provide breast surgical oncology leadership across the Smilow Cancer...

hepatobiliary cancer
genomics/genetics

In Cholangiocarcinoma, Does Chemotherapy Response Vary According to FGFR2 Status?

With inhibitors of fibroblast growth factor receptor 2 (FGFR2) fusion and other genetic alterations now in clinical trials for cholangiocarcinoma, there is interest in better understanding what FGFR2 genetic alterations mean for patients. In particular, little is known about the effects of FGFR2...

covid-19

David Fajgenbaum, MD, MBA, on Repurposing Cancer Drugs to Treat COVID-19

David Fajgenbaum, MD, MBA, of the University of Pennsylvania, talks about his research efforts to find an already-approved drug that could treat his orphan disease—multicentric Castleman disease—and how that methodology may be applied to the coronavirus and the cytokine storm it can cause...

global cancer care

Cancer on the Global Stage: Incidence and Cancer-Related Mortality in Kenya

The ASCO Post is pleased to continue this occasional special focus on the worldwide cancer burden. In this issue, we feature a close look at the cancer incidence and mortality rates in Kenya. The aim of this special feature is to highlight the global cancer burden for various countries of the...

lymphoma
immunotherapy

B-Cell and T-Cell Non-Hodgkin Lymphomas

To complement The ASCO Post’s continued comprehensive coverage of the 2020 American Society of Hematology (ASH) Annual Meeting & Exposition, here are several abstracts selected from the meeting proceedings focusing on the assessment and treatment of patients with B-cell and T-cell non-Hodgkin...

skin cancer

High-Risk Cutaneous Squamous Cell Carcinomas: The Present and Future

Cutaneous squamous cell carcinoma is the second most common type of skin cancer, with more than 1 million cases diagnosed in the United States annually.1 Historically, cutaneous squamous cell carcinoma is grouped together with basal cell carcinoma and collectively referred to as nonmelanoma skin...

Miami Cancer Institute Appoints New Deputy Director, Chief Scientific Officer, and Chief of Solid Tumor Medical Oncology

Neuro-oncologist and medical oncologist Manmeet Ahluwalia, MD, FACP, MBA, has joined Miami Cancer Institute as Deputy Director, Chief Scientific Officer and Chief of Solid Tumor Medical Oncology. Board-certified in internal medicine, medical oncology, neuro-oncology and hematology, Dr. Ahluwalia...

lung cancer
covid-19

WCLC Press Briefing Focuses on the Connection Between Lung Cancer and COVID-19

On February 27, 2020, the Journal of Thoracic Oncology published a case study that described two patients from Wuhan, China, who had recently underwent lung lobectomies for adenocarcinoma and were retrospectively found to have had COVID-19 at the time of surgery. Eleven months later, the lung...

global cancer care
covid-19

World Cancer Day 2021 to Focus on Adaptations and Innovations in Cancer Care Through COVID-19 and Beyond

To mark World Cancer Day on February 4, the Union for International Cancer Control (UICC) will give voice to and say thank you to the nurses, doctors, researchers, volunteers, advocates, and other caregivers in oncology from around the world, as well as government agencies, who have worked through...

Winners of 40 Under 40 in Cancer Awards Announced

40 Under 40 in cancer is an awards initiative to identify and recognize contributions from across the field of oncology by approximately rising stars and emerging leaders younger than 40. Awardees were nominated by colleagues and selected by a panel of reviewers from a range of areas in oncology....

global cancer care

Indian Surgical Oncologist Offers Insights Into Delivering Equitable Cancer Care in a Resource-Challenged Country

The ASCO Post is pleased to introduce this department on Global Health-Care Equity. On an occasional basis, we will publish interviews between Guest Editor, Chandrakanth Are, MBBS, MBA, FRCS, FACS, and another oncologist or cancer care specialist spanning regions around the world. Our goal is to...

City of Hope Announces Its First Chief Diversity, Equity, and Inclusion Officer

City of Hope, an independent cancer and diabetes research and treatment center, has welcomed Angela L. Talton, MBA, to its executive leadership team as Senior Vice President and Chief Diversity, Equity, and Inclusion Officer. Ms. Talton will provide leadership for City of Hope’s efforts to build a...

global cancer care

Cancer on the Global Stage: Incidence and Cancer-Related Mortality in Burkina Faso

The ASCO Post is pleased to continue this occasional special focus on the worldwide cancer burden. In this issue, we feature a close look at the cancer incidence and mortality rates in Burkina Faso. The aim of this special feature is to highlight the global cancer burden for various countries of...

Community Oncology Alliance Elects New President, Officers, and Board Members

The Community Oncology Alliance (COA), a nonprofit advocacy group dedicated solely to independent oncology practices and the patients they serve, recently announced the election of Kashyap Patel, MD, as President. A longtime COA Board of Directors member and community oncology champion, Dr. Patel...

covid-19

COA Submits Letter to Governors, Public Health Officials to Request Independent Oncology Practices Be Given Priority Approval to Administer COVID-19 Vaccines

Today, leadership from the Community Oncology Alliance (COA) sent a letter urging the nation's governors and public health officials to prioritize supplying cancer treatment practices with COVID-19 vaccines and allowing the practices to administer the vaccines. The letter, signed by Kashyap Patel,...

issues in oncology
global cancer care

Addressing Inequality in Cancer Care on a Global Scale

It has become a familiar theme of late: Inequities exist in all aspects of cancer care. Although study after study documents problems with access to care and poorer cancer outcomes among underrepresented groups, less is heard about organized efforts to address these issues. This critical topic was...

issues in oncology

Postoperative Cancer Surgery Mortality Rates Have Improved, but Gap Still Exists Between Black and White Patients

Mortality rates after cancer surgery declined for Black as well as White patients during a recent 10-year period, although the mortality gap between the two groups did not narrow, according to new research published by Miranda Lam, MD, MBA, and colleagues in JAMA Network Open. The findings present...

City of Hope Orange County Names Edward S. Kim, MD, MBA, Its Physician-in-Chief

CITY OF HOPE ORANGE COUNTY recently announced the appointment of cancer researcher and clinician Edward S. Kim, MD, MBA, as Senior Vice President and Vice Physician-in-Chief at City of Hope and Orange County Physician-in-Chief. “Dr. Kim has a depth and breadth of cancer expertise that is well...

Abraham Chachoua, MD, Announced as New Director of Perlmutter Cancer Center’s Lung Cancer Center

New York University (NYU) Langone Health’s Perlmutter Cancer Center recently appointed Abraham Chachoua, MD, as the new Director of Perlmutter Cancer Center’s Lung Cancer Center. Dr. Chachoua currently serves as the Jay and Isabel Fine Professor of Oncology and Professor of Urology at NYU...

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