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legislation

Medicaid Expansion Is Associated With Increased Survival in Newly Diagnosed Patients With Cancer

A large study led by researchers at the American Cancer Society showed that Medicaid expansion under the Affordable Care Act (ACA) was associated with an increase in 2-year overall survival rates among patients newly diagnosed with cancer, especially among non-Hispanic Black people and people...

issues in oncology

The Future of Community Oncology Practice

Although community oncology practice may have been changing before the COVID-19 pandemic, it amplified industry trends. At the 2022 Community Oncology Alliance’s Community Oncology Conference, a panel of experts discussed issues related to the future of community cancer care, including...

bladder cancer
genomics/genetics

Report Finds Uptake of Erdafitinib for Urothelial Cancer May Be Limited, Despite Positive Real-World Survival Data

The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a report published as a research letter by Nimgaonkar et al in JAMA Oncology. Researchers analyzed a large, nationwide database of cancer...

ASCO Honors 2022 Special Awards Recipients

ASCO and Conquer Cancer, the ASCO Foundation, will recognize researchers, patient advocates, philanthropists, teachers, and global oncology leaders who have reshaped cancer care around the world with the Society’s highest honors at the 2022 ASCO Annual Meeting in Chicago. Hear from select award...

multiple myeloma

Going the Last Mile: Accelerating Delivery of Multiple Myeloma Therapies to All Patients

When I was diagnosed with multiple myeloma in 1996, I was given 3 years to live. At the time, there was little understanding of this disease, which was termed incurable. There were no new treatments, few drugs in the pipeline, hardly any clinical trials, and no multiple myeloma community or...

health-care policy
cost of care

Study Shows Medical Financial Hardship Increases Mortality Risk for Cancer Survivors

New findings from a large national study led by researchers at the American Cancer Society (ACS) show cancer survivors in the United States who reported medical financial hardship had a higher mortality risk than cancer survivors without financial hardship. Medical financial hardship was measured...

Supporting and Mobilizing Resources: ASCO Joins Worldwide Efforts to Support Ukrainian Cancer Care

“Refugees and displaced people may see their cancer treatment interrupted, or they may develop a new cancer while they are in host countries. They often present with advanced disease and suffer more complications. These patients have poor outcomes because of poor hygiene and living conditions, as...

American Cancer Society Awards $16 Million in Grants to Establish Cancer Health Equity Research Centers

The American Cancer Society has awarded more than $16 million in grants to establish Cancer Health Equity Research Centers (CHERC) at minority-serving institutions. The inaugural cohort of institutions includes the Arizona Board of Regents–University of Arizona, the University of Illinois at...

hepatobiliary cancer
immunotherapy

HIMALAYA Trial: First-Line Tremelimumab Plus Durvalumab Improves Overall Survival in Unresectable Hepatocellular Carcinoma

Patients with advanced, unresectable hepatocellular carcinoma may be gaining another first-line treatment option. In the global phase III HIMALAYA trial, a single priming dose of tremelimumab plus regular-interval durvalumab significantly improved overall survival, according to Ghassan K....

hepatobiliary cancer
immunotherapy

RATIONALE 208: ‘Durable Clinical Activity’ Reported With Tislelizumab in Advanced Liver Cancer

With the investigational checkpoint inhibitor tislelizumab, durable responses were achieved by some patients with previously treated advanced hepatocellular carcinoma, regardless of the number of prior lines of therapy, in the phase II RATIONALE 208 trial. These findings were presented during the...

gastroesophageal cancer

Adjuvant Nivolumab Improves Disease-Free Survival vs Placebo in Resected Esophageal or Gastroesophageal Junction Cancer After Neoadjuvant Chemoradiotherapy

As reported in The New England Journal of Medicine by Ronan J. Kelly, MB BCh, MBA, of The Charles A. Sammons Cancer Center at Baylor University Medical Center, and colleagues, an interim analysis of the phase III CheckMate 577 trial has shown a significant improvement in disease-free survival with ...

American Cancer Society Names Arif Kamal, MD, First Chief Patient Officer

The American Cancer Society (ACS) has named Arif Kamal, MD, MBA, MHS, FACP, ­FAAHPM, FASCO, as its first Chief Patient Officer to lead its patient support vision and strategic plans to improve the lives of patients with cancer and their families. Based in Chapel Hill, North Carolina, Dr. Kamal will ...

Robert Otto Valdez, PhD, MHSA, Named Director of the AHRQ

Robert Otto Valdez, PhD, MHSA, was appointed Director of the Agency for Healthcare Research and Quality (AHRQ) in February 2022. He was previously the Robert Wood Johnson Foundation (RWJF) Professor Emeritus of Family & Community Medicine and Economics at the University of New Mexico (UNM). In...

ACCC Appoints David R. Penberthy, MD, MBA, as New President

David R. Penberthy, MD, MBA, was recently named President of the Association of Community Cancer Centers (ACCC) at the organization’s 48th Annual Meeting and Cancer Center Business Summit. Oncology professionals from around the nation gathered at the conference to discuss the convergence of...

issues in oncology
bladder cancer
kidney cancer
prostate cancer

Karen E. Knudsen, PhD, MBA, on Addressing Disparities in Genitourinary Cancers

Karen E. Knudsen, PhD, MBA, Chief Executive Officer of the American Cancer Society, discusses ways to address the inequities in genitourinary screening, treatment, and outcomes. Her suggestions focus on increasing awareness of screening, identifying risk factors, the dramatic rise in incidence...

Patricia L. Turner, MD, MBA, FACS, Takes Helm of American College of Surgeons

Patricia L. Turner, MD, MBA, FACS, formally assumed the role of Executive Director of the American College of Surgeons (ACS) on January 1, 2022, ushering in a new era of leadership for the educational and professional society for surgeons. Dr. Turner succeeds David B. Hoyt, MD, FACS, MAMSE, who led ...

ASCO and American Cancer Society Announce Collaboration to Empower People With Cancer Information They Can Trust

ASCO and the American Cancer Society (ACS) initiated a collaboration to ensure that people can easily find the trusted, expert-approved cancer content they need when turning to either organization for information. As an initial step, the organizations are cross-sharing select cancer prevention,...

issues in oncology

American Cancer Society Publishes Cancer Statistics for African American/Black People 2022

In a major shift, breast cancer has surpassed lung cancer as the leading cause of cancer death among Black women as of 2019. This news is one of the key findings in a new report from the American Cancer Society, Cancer Statistics for African American/Black People 2022, published by Giaquinto et al...

global cancer care

Cancer on the Global Stage: Incidence and Cancer-Related Mortality in the Russian Federation

The Russian Federation is the largest country in the world, extending from Eastern Europe to Northern Asia and the Pacific Ocean. The population of more than 140 million people is unevenly distributed across the country.1 As a result, Russia has high spatial inequality in terms of accessibility of...

hepatobiliary cancer
immunotherapy

HIMALAYA Trial: First-Line Tremelimumab Plus Durvalumab Improves Overall Survival in Unresectable Hepatocellular Carcinoma

Patients with advanced, unresectable hepatocellular carcinoma may be gaining another first-line treatment option. In the global phase III HIMALAYA trial, a single priming dose of tremelimumab plus regular-interval durvalumab significantly improved overall survival, according to Ghassan K....

ASCO and American Cancer Society Announce Collaboration to Empower People With Cancer Information They Can Trust

ASCO and the American Cancer Society (ACS) today initiated a collaboration to ensure that people can easily find the trusted, expert-approved cancer content they need when turning to either organization for information. As an initial step, the organizations are cross-sharing select cancer...

hepatobiliary cancer
immunotherapy

Ghassan K. Abou-Alfa, MD, MBA, on Hepatocellular Carcinoma: Open-Label Trial of Tremelimumab and Durvalumab

Ghassan K. Abou-Alfa, MD, MBA, of Memorial Sloan Kettering Cancer Center and Weill Medical College at Cornell University, discusses phase III results of the HIMALAYA trial, which showed the combination of a single priming dose of tremelimumab added to durvalumab is superior to sorafenib for...

global cancer care

Cancer on the Global Stage: Incidence and Cancer-Related Mortality in Burundi

The ASCO Post is pleased to continue this occasional special focus on the worldwide cancer burden. In this issue, we feature a close look at the cancer incidence and mortality rates in Burundi. The aim of this special feature is to highlight the global cancer burden for various countries of the...

An Adventurous Spirit Led to a Prominent Role in Radiation Oncology for Geraldine Jacobson, MD, MPH, MBA, FACR, FASTRO

Geraldine Jacobson, MD, MPH, MBA, FACR, FASTRO, founding Chair of the West Virginia University (WVU) Department of Radiation Oncology, was born in Fort Dix, New Jersey. Her father was a military officer, and his various duty posts offered an adventurous childhood for Dr. Jacobson. “One of my...

Tennessee Oncology Appoints Stephen Schleicher, MD, MBA, as Chief Medical Officer and Natalie Dickson, MD, as Chief Strategy Officer

Tennessee Oncology, one of the largest providers of oncology care in the country, announced that Stephen Schleicher, MD, MBA, has been appointed Chief Medical Officer (CMO) effective January 1, 2022. Natalie Dickson, MD, President and CMO, will remain in her role as President of the company while...

Ian E. Krop, MD, PhD, Named Chief Clinical Research Officer, Associate Cancer Center Director for Clinical Research at Yale Cancer Center

Ian E. Krop, MD, PhD, has been appointed Chief Clinical Research Officer, Associate Cancer Center Director for Clinical Research, and Director of the Yale Cancer Center Clinical Trials Office. Dr. Krop will assume his new position on March 2, 2022. “I’m pleased to announce Dr. Krop will work with ...

hepatobiliary cancer
immunotherapy

Durvalumab/Tremelimumab Improves Overall Survival vs Sorafenib in Patients With Advanced Hepatocellular Carcinoma: HIMALAYA

Results from the randomized international phase III HIMALAYA trial showed that a combination of the anti–PD-L1 immunotherapy durvalumab plus the anti–CTLA-4 immunotherapy tremelimumab reduced the risk of death by 22% in patients with stage III or IV unresectable hepatocellular carcinoma compared to ...

global cancer care

UICC to Launch 3-Year Campaign to Create More Equitable Access to Cancer Services

On February 4, 2022, the Union for International Cancer Control (UICC) will launch a new 3-year campaign for World Cancer Day that brings together individuals, organizations, and governments around the world in an effort to create awareness and help close the gap in cancer care. The campaign...

hematologic malignancies

New Study Examines Septic Shock in Patients With Hematologic Malignancies

Research published by Manjappachar et al in JNCCN—Journal of the National Comprehensive Cancer Network examined the impact of septic shock on people with hematologic malignancies. They found that the mortality rate was 67.8% at 28 days, and only 19.4% of patients remained alive after 90 days. The...

NYU Langone Opens Center Dedicated to Blood and Marrow Transplants

NYU Langone Health’s Laura and Isaac Perlmutter Cancer Center opened a new state-of-the-art center to treat people with hematologic malignancies, including leukemia, lymphoma, and multiple myeloma. The new center, led by Samer Al-Homsi, MD, MBA, Clinical Professor in the Department of Medicine and...

covid-19

Positive Practice Changes After the COVID-19 Pandemic: From the Advanced Practice Provider Perspective

The COVID-19 pandemic may have changed some aspects of health care forever. At the 2021 JADPRO Live Virtual event, a panel discussion focused on how several cancer centers faced challenges, and what changes the participants view as positive.1 JADPRO Live is an annual educational conference for...

Erudition and Assessment on the Longest War in the Modern Era

A little after noon on December 23, 1971, President Richard Nixon entered the White House state dining room. Before 137 esteemed guests from government, science, and industry, he signed the landmark National Cancer Act. It was, in short, a national commitment to conquer cancer. President Nixon...

Last Hug

“Good evening, doc; I wanted to check on you and update you on my mom” read the text message on a late Thursday afternoon. I recognized the sender; it was not uncommon for me to share my cell phone number with patients and their families. Having been a caretaker of my own parents’ medical needs, I...

Eric P. Winer, MD, FASCO, to Lead Yale Cancer Center and Smilow Cancer Hospital

After an extensive national search, Yale School of Medicine and Yale New Haven Health have announced that Eric P. Winer, MD, FASCO, will be the next Director of Yale Cancer Center and Physician-in-Chief of Smilow Cancer Hospital at Yale New Haven, effective February 1, 2022. Nita Ahuja, MD, MBA,...

issues in oncology

The Promise and the Challenge: Experts and Innovators Explore the Impact of New Technologies in Cancer Care

Artificial intelligence, digital therapeutics, telehealth, biometric monitoring: the terms alone are enough to suggest that cancer care is entering a new age, one characterized by tools and practices based on technologic innovation. To explore the impact of these new tools, the National...

MSK Appoints Saad Z. Usmani, MD, MBA, FACP, Chief of Myeloma Service

Physician leader and clinical and translational investigator Saad Z. Usmani, MD, MBA, FACP, recently joined Memorial Sloan Kettering Cancer Center (MSK) as Chief of Myeloma Service. He was also appointed Professor at the Joan & Sanford I. Weill Medical College of Cornell University. Dr....

multiple myeloma
immunotherapy

High-Risk Multiple Myeloma: Combination Regimens and CAR T-Cell Therapy

“Continuous improvement is better than delayed perfection.”  —Mark Twain To complement The ASCO Post’s extensive coverage of the 2021 ASCO Annual Meeting, here are several abstracts selected from the meeting proceedings focusing on novel treatments under study in high-risk multiple myeloma. For...

cost of care

Annual Report to the Nation, Part 2: Focus on Patient Economic Burden Associated With Cancer Care

Part 2 of the latest Annual Report to the Nation on the Status of Cancer—provided by the American Cancer Society, National Cancer Institute, Centers for Disease Control and Prevention, and North American Association of Central Cancer Registries—has found that patients with cancer in the United...

issues in oncology

JCO OP Special Series: Disparities in Cancer Care for Hispanic-Latinx People

JCO Oncology Practice is now accepting manuscripts for a special issue on disparities in cancer care for Hispanic-Latinx people. Submit your manuscript today at https://www.editorialmanager.com/op-ascopubs/default.aspx Guest Editors Miguel Villalona-Calero, MD; Gilberto Lopes, MD, MBA; Narjust...

global cancer care

Cancer on the Global Stage: Incidence and Cancer-Related Mortality in Bhutan

Located in the Eastern Himalayas, Bhutan is a landlocked, lower–middle-income country bordered by China and India. With a population of more than 850,000 people, Bhutan is predominately made up of three ethnic groups—the largest group is the Bhutia (also called Ngalop), followed by the Nepalese...

Michael Diaz, MD, Named President and Managing Physician at Florida Cancer Specialists & Research Institute

Florida Cancer Specialists & Research Institute (FCS) recently appointed Michael Diaz, MD, to the position of President and Managing Physician, effective January 1, 2022. Dr. Diaz succeeds Lucio Gordan, MD, who has served in that position since 2018. Dr. Gordan will continue to practice as a...

breast cancer

Katherine E. Reeder-Hayes, MD, MBA, on Geography, Breast Cancer Treatment, and Racial Disparities

Katherine E. Reeder-Hayes, MD, MBA, of the University of North Carolina at Chapel Hill, discusses the timeliness of breast cancer care for Black women compared with non-Black women in North Carolina. Her data showed that greater geographic variation exists in the timeliness of breast cancer care...

issues in oncology

John V. Cox, DO, MBA, on Reshaping Practice Models to Better Care for Patients With Cancer

John V. Cox, DO, MBA, of The University of Texas Southwestern Medical Center, summarizes his Joseph V. Simone Lecture, in which he stressed the need for coordinated care among practices. The concept of oncology medical homes, he says, has evolved to a broader-based model in which oncologists...

Breast Cancer Research Foundation®, Conquer Cancer, and ASCO Celebrate 20th Year of Collaboration

2021 marks the 20th year of collaboration between ASCO; Conquer Cancer®, the ASCO Foundation; and the Breast Cancer Research Foundation® (BCRF). BCRF’s pivotal support during the past 2 decades has been critical to both organizations’ shared achievements in funding breakthroughs in breast cancer...

colorectal cancer

Radioembolization Plus Second-Line Chemotherapy for Colorectal Liver Metastases

In the phase III EPOCH trial reported in the Journal of Clinical Oncology, Mary F. Mulcahy, MD, and colleagues found that the addition of transarterial yttrium-90 radioembolization (TARE) to second-line chemotherapy significantly prolonged progression-free survival and hepatic progression–free...

global cancer care

Cancer on the Global Stage: Incidence and Cancer-Related Mortality in Brunei Darussalam

With a population under half a million people, Brunei Darussalam is a small equatorial nation in Southeast Asia. Bordered by the South China Sea on the north, Brunei Darussalam is surrounded on all other sides by Malaysia, which separates the nation into two noncontiguous parts.  Nearly two-thirds...

hematologic malignancies
global cancer care

Paradox Between Cost and Hematopoietic Cell Transplant Rate in Latin America

In this installment of The ASCO Post’s Global Oncology series, Guest Editor Chandrakanth Are, MBBS, MBA, FRCS, FACS, spoke with Gregorio Jaimovich, MD, Director of the Bone Marrow Transplant Program at Favaloro University Hospital in Buenos Aires. Distinguished expert on radiation therapy and bone...

multiple myeloma
immunotherapy

Saad Z. Usmani, MBA, MD, on Multiple Myeloma: Updated Results From the CARTITUDE-1 Study of Ciltacabtagene Autoleucel

Saad Z. Usmani, MBA, MD, of the Levine Cancer Institute, discusses new data on the CAR T-cell therapy ciltacabtagene autoleucel, a single infusion of which yielded early, deep, and durable responses in heavily pretreated patients with relapsed or refractory multiple myeloma (Oral Abstract MM-119).

breast cancer

Association of Pathologic Residual Cancer Burden and Event-Free Survival After Neoadjuvant Treatment for High-Risk Breast Cancer

In an analysis from the I-SPY2 trial reported in JAMA Oncology, W. Fraser Symmans, MD, and colleagues found that increasing residual cancer burden after neoadjuvant treatment for high-risk breast cancer was associated with poorer event-free survival. Study Details In I-SPY2, investigational agents...

Conquer Cancer Names Inaugural Recipients of ASCO Registry Research Grants

Conquer Cancer, the ASCO Foundation, is pleased to announce the recipients of its 2021 ASCO Registry Research Grants.  Conquer Cancer established the ASCO Registry Research Grant to support research using data derived from the ASCO Survey on COVID-19 in Oncology Registry (the “ASCO Registry”). The...

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