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gynecologic cancers

Nine-Valent HPV Vaccine May Prevent Nearly 90% of Cervical Cancers

Because nine human papillomavirus (HPV) subtypes were found to cause the majority of cervical precancers, a nine-valent HPV vaccine currently being investigated may be able to prevent more cervical cancers than current vaccines, according to research published in Cancer Epidemiology, Biomarkers...

Patient Guides Available Through ASCO University Bookstore

ASCO Answers: Managing the Cost of Cancer Care explains the various costs associated with cancer treatment, including health-care coverage through the Affordable Care Act. It also provides a list of financial resources available to help offset expenses related to care and tips for organizing...

issues in oncology

Fear

The following essay by Michael Feinstein, MD, is excerpted from The Big Casino: America’s Best Cancer Doctors Share Their Most Powerful Stories, which was co-edited by Stan Winokur, MD, and Vincent Coppola and published in May 2014. The book is available on Amazon.com and thebigcasino.org....

Roswell Park Researchers Awarded Nearly $5 Million to Support Research Projects

Several faculty members at Roswell Park Cancer Institute have been awarded nearly $5 million in grant funding from public and private organizations to further their efforts to find new and better ways to detect and treat cancer and improve patients’ quality of life. The 13 awards, including two for ...

2014 Oncology Meetings

OCTOBER 18th SIS World Congress on Breast HealthcareOctober 16-19 • Orlando, Florida For more information: www2.kenes.com/sis/Pages/Home.aspx 2014 Quality Care SymposiumOctober 17-18 • Boston, MassachusettsFor more information: quality.asco.org Atlanta Lung Cancer SymposiumOctober 18 • Atlanta,...

survivorship

New Books by Authors at Memorial Sloan Kettering Cancer Center Address Aging, Survivorship

Bookmark Title: Survivorship: Living Well During and After CancerAuthor: Barrie Cassileth, PhDFormat: PaperbackISBN: 978-1-938170-35-5Pages: 216Publication Date: April 1, 2014Dimensions: 5.5 × 8.5Also Available: eBook   Bookmark Title: Lighter as We Go: Virtues, Character Strengths, and...

Ketan K. Badani, MD, Additional Staff, Appointed to Mount Sinai Health System

Ketan K. Badani, MD, Professor of Urology, Icahn School of Medicine at Mount Sinai in New York, has been named Vice Chairman of Urology and Robotic Operations and Director of the Comprehensive Kidney Cancer Program for the Mount Sinai Health System. Dr. Badani will also serve as Director of Robotic ...

colorectal cancer
lung cancer
gastroesophageal cancer

Researchers at Roswell Park Receive Grants to Study New Anticancer Agent in Lung, Colorectal, and Gastrointestinal Cancers

Researchers at Roswell Park Cancer Institute have been awarded three of four grants by the National Comprehensive Cancer Network (NCCN) Oncology Research Program to evaluate and define the clinical effectiveness of the investigational compound nintedanib. Nintedanib is an investigational...

lung cancer

James Herman, MD, Named Co-Leader of UPCI Lung Cancer Program

A leader in the field of epigenetics whose work has led to important discoveries into how cancer develops and progresses has been named the co-leader of the Lung Cancer Program at the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter. James Herman, MD, comes to...

gynecologic cancers

Genetic ‘Hotspot’ Linked to Endometrial Cancer Aggressiveness

Parents of twins often tell them apart through subtle differences such as facial expression, moles, voice tone, and gait. Similarly, physicians treating women with endometrial cancer must be able to distinguish between different versions of this disease form that, on the surface, appear the same....

solid tumors

Sluys-Kessler Radium Apparatus, Paris, 1930

Devices to accurately deliver high-dose radium therapy became extremely sophisticated during the late 1920s. In this photograph, the patient is being treated for a carcinoma of the back by a Sluys-Kessler machine. This apparatus could also accurately deliver therapy for a wide variety of internal...

lymphoma

Lympho-Sarcoma Treated by Radiation, Patient of Francis H. Williams, MD, Boston, 1902

One of the miracles produced by the x-ray was the relatively easy treatment of inoperable or disfiguring tumors. If not a cure, the results frequently gave the patients at least some time to look and feel normal. The young patient shown in these photographs had a remarkable response. Images such as ...

breast cancer

First Photographs of Breast Surgery, New York City, 1886

Antiseptic principles delivered the promise of safe surgery, while asepsis allowed safe major dissections and invasion of body cavities. The physicians who were using these techniques recognized the amazing difference in their surgical results and corresponding mortality rates and proselytized to...

gynecologic cancers

Woman With Ovarian Tumor, Daguerreotype, Wellington, Ohio, June 1851

In June 1851, Philip J. Bruckner, MD, hired a daguerreotypist to photograph this 275-pound, 33-year-old woman, who had borne five children while developing this massive tumor. Dr. Bruckner learned of this patient when Charles Breech, MD, of Wellington, Ohio, presented her case at a medical meeting. ...

100 Years of Progress in Oncology Treatment

In his powerful 2010 best-seller, The Emperor of All Maladies: A Biography of Cancer (Scribner), Siddhartha Mukherjee, MD, chronicles the evolution of cancer from the oldest known description of the disease written on a papyrus from about 1600 BC to the present day’s understanding of the biology of ...

supportive care

One in Three People With Cancer Has Anxiety or Other Mental Health Challenges

Researchers in Germany report that nearly a third of more than 2,100 patients with cancer interviewed at inpatient and outpatient care centers experienced a clinically meaningful level of mental or emotional distress that meets the strict diagnostic criteria for mental disorders including anxiety...

issues in oncology
palliative care

Helping Patients Talk to Their Children About Cancer

Although the focus of an oncologist’s attention is understandably attuned to the needs of the patient, when a patient is a parent, quality oncology care should also include attention to the patient’s role as a parent and to the needs of the patient’s children, according to Paula K. Rauch, MD,...

issues in oncology

ASCO Calls for New Action to Address Obesity and Cancer

ASCO has called for increased education, research, and advocacy to reduce the toll of obesity, both as a leading cause of cancer and a complication in the care of patients with cancer. The Society’s recommendations outline four critical priorities, including increased education and awareness about...

issues in oncology

Now in Its 71st Year, CancerCare Looks to  Expand Services to Patients and Caregivers

Eleven days before Patricia J. ­Goldsmith, joined CancerCare as its CEO last May, she received the unexpected news that she had early-stage colorectal cancer. While the diagnosis was shocking, Ms. Goldsmith said it gave her a unique perspective on what it means to have this serious disease and a...

global cancer care

Effective Prevention Measures Urgently Needed to Prevent Global Cancer Crisis

Earlier this year the International Agency for Research on Cancer (IARC), an agency of the World Health Organization, launched a World Cancer Report 2014. The report, a collaboration of over 250 leading scientists from more than 40 countries, described multiple aspects of cancer research and...

breast cancer
global cancer care

Breaking the Silence About Breast Cancer in the Arab World

In 1974, First Lady Betty Ford spoke publicly about her breast cancer diagnosis and treatment. Remarkably, at the time of her action, public discussion of breast cancer in the United States was seen as off limits. Four decades later, cultural barriers to women’s health still exist, particularly in...

Radiation Oncologist Stephen Hahn, MD, to Join MD Anderson

Stephen Hahn, MD, has been named as the Division Head of Radiation Oncology and Chair of the Department of Radiation Oncology at The University of Texas MD Anderson Cancer Center. He joins MD Anderson on January 1, 2015. Dr. Hahn comes to MD Anderson from the University of Pennsylvania’s Perelman...

issues in oncology

On Being A Mentee and the Value of the Conquer Cancer Foundation’s Career Development Award

At the ASCO Annual Meeting in June, the Conquer Cancer Foundation presented the 2014 recipients of prestigious grants and awards, including the Young Investigator Award, Career Development Award, and the Advanced Clinical Research Award in Breast Cancer. In announcing the awards, Charles W. Penley, ...

issues in oncology

The Value of Lifelong Mentorship in Career Development

While the development of mentorship relationships is critical in launching and nurturing the academic careers of young investigators, it is also an essential component for continued success throughout their careers, according to Jennifer R. Brown, MD, PhD. Dr. Brown, Director of the CLL Center at...

global cancer care
gastrointestinal cancer

IARC Calls on Countries With High Stomach Cancer Burden to Act to Prevent the Disease

A new report from the International Agency for Research on Cancer (IARC), an agency of the World Health Organization, urges health authorities of countries with high stomach cancer burden to include stomach cancer in their national cancer control programs and allocate more resources to control the...

sarcoma

Treating Sarcomas in 2014

In 2014, about 15,000 people in the United States will be diagnosed with some form of sarcoma, and of those, approximately 5,000 adults and children are expected to die of the disease. Sarcomas are a heterogeneous group of mesenchymal malignancies that have historically been difficult to diagnose...

supportive care

Improving Treatment of Depression in Patients With Cancer: The SMaRT Oncology-2 Trial

Clinical depression is highly prevalent, associated with significant morbidity, often underrecognized, and inadequately treated in cancer patients.  Professor Michael Sharpe and Jane Walker, PhD, and their colleagues’ seminal work on enhancing treatment of depression in cancer patients using a...

cns cancers

Failure of Cilengitide in Newly Diagnosed Glioblastoma With Methylated MGMT Promoter

Temozolomide in combination with radiation for newly diagnosed glioblastoma was approved by the U.S. Food and Drug Administration in 2005—almost 10 years ago—but we have unfortunately made little progress in improving survival for this incurable brain tumor. Despite recent completion of three...

hematologic malignancies

Louis J. DeGennaro, PhD, Named President and Chief Executive Officer of The Leukemia & Lymphoma Society

The Leukemia & Lymphoma Society has announced that Louis J. DeGennaro, PhD, has been appointed as President and Chief Executive Officer, effective immediately. “Dr. DeGennaro has tirelessly dedicated himself for almost a decade of service to the Leukemia & Lymphoma Society mission and to...

survivorship
cost of care

Cancer Survivors Face Lasting Financial Struggles Long After Treatment Ends, New Study Reports

The majority (62%) of America’s middle-income cancer survivors say they were not financially prepared for cancer diagnosis and treatment, according to a new study released by the Washington National Institute for Wellness Solutions (IWS). The study, “Insights from Survivors: Managing the Personal,...

lymphoma

ECOG E4402/RESORT Trial: When ‘Black and White’ Results Are Actually Gray

The results of the ECOG E4402/RESORT trial recently reported by Kahl and colleagues,1 and reviewed in this issue of The ASCO Post, provide interesting new information on the use of maintenance rituximab (Rituxan) vs retreatment with rituximab at progression in patients with low–tumor burden...

pancreatic cancer

Early Study Reports Modified Vitamin D Has Potential in Treatment for Pancreatic Cancer

Researchers at the Salk Institute have reported on a synthetic derivative of vitamin D able to collapse the barrier of cells shielding pancreatic tumors, making this challenging cancer more susceptible to therapeutic drugs. The discovery has led to human trials for pancreatic cancer, even in...

colorectal cancer

Colonoscopic Polypectomy and Predicting Cancer Risk: A Work in Progress

Colon cancer screening using colonoscopy has significantly decreased the incidence and mortality of colorectal cancer in the United States. In the National Polyp Study (NPS), colorectal cancer was prevented by removal of adenomatous polyps.1 A more recent study looking at long-term follow-up from...

kidney cancer

Advanced Robotic Technology Used to Remove Kidney Tumor in First-Time Outpatient Procedure

Keck Medical Center of the University of Southern California (USC) has become the first medical center in the world to use a new robotic technology in an outpatient procedure for a patient with kidney cancer. Urologic surgeons at the USC Institute of Urology, part of Keck Medicine of USC, used a...

issues in oncology

Exceptional Responders to Cancer Therapy Study Begins

The National Cancer Institute (NCI) recently launched “The Exceptional Responders Initiative,” a study to investigate the molecular factors of tumors associated with exceptional treatment responses of patients with cancer to drug therapies. Scientists will attempt to identify the molecular features ...

pain management

Despite Growing Awareness, the Global Crisis of Untreated Cancer Pain Persists

Each day, millions of patients with cancer around the world suffer unrelieved pain because they are denied morphine, the gold standard of cancer pain control. The World Health Organization has called access to morphine a human rights issue. Not surprisingly, the crisis in unrelieved cancer pain is...

Ohio State Opens First Fully Integrated Cancer Emergency Department

For patients with cancer who already have compromised immune systems, what may seem like a minor medical issue—ie, fever, dehydration, viral infection—can rapidly escalate into an emergency situation requiring care from a medical team familiar with managing the side effects of cancer treatment....

breast cancer

Women at Higher Risk for Breast Cancer to Benefit From Hereditary Risk Assessment Program in Tucson Center

Approximately 12% of women in the United States will develop breast cancer, according to the American Cancer Society. That’s more than 30,000 in Tucson alone, 2,500 of whom are estimated to have a genetic risk factor for cancer. In response to this growing concern, The Breast Center at Carondelet...

global cancer care

NCI’s Center for Global Health Announces First Major Research Grants to Support Portable Technologies

The National Cancer Institute (NCI) Center for Global Health announced grants that will support the development and validation of low-cost, portable technologies. These technologies have the potential to improve early detection, diagnosis, and noninvasive or minimally invasive treatment of several...

gynecologic cancers

Attaining the Goal of Preventing Ovarian Cancer

Fifteen years ago, David Fishman, MD, launched the National Ovarian Cancer Early Detection Program as part of the National Cancer Institute’s Early Detection Research Network. The goal of the research effort was to develop methods to accurately detect ovarian cancer while it was still confined to...

gynecologic cancers

Call for Ideas for Ovarian Cancer Translational Research ‘Dream Team’ Grant

The American Association for Cancer Research (AACR) is accepting submissions of ideas for the Stand Up To Cancer–Ovarian Cancer Research Fund–Ovarian Cancer National Alliance–National Ovarian Cancer Coalition (SU2C-OCRF-­OCNA-NOCC) Translational Research Dream Team Grant that will offer up to $6...

breast cancer

Guidelines and Care: What Comes Next?

The goal of clinical, translational, and basic research is, in the end, the betterment of life on earth. Advances in basic and clinical science ultimately should lead to information that, in turn, enables clinicians to make better treatment decisions for individual patients in order to improve...

Society Announces Candidates for 2015 ASCO Election

Fourteen distinguished ASCO members have been selected by the ASCO Nominating Committee as candidates for open leadership positions within the Society for the 2015 ASCO Election. Biographical information and interviews with each candidate, as well as instructions for casting a proxy ballot, will be ...

lung cancer

REVEL: Winning a Questionable Race

The investigators and sponsors of the phase III REVEL trial should be congratulated and probably commiserated. In this large study, reported by Garon and colleagues in The Lancet and reviewed in this issue of The ASCO Post, 1,253 patients with advanced non–small cell lung cancer (NSCLC) were...

lung cancer

Significant Improvement in Overall Survival With Second-Line Addition of Ramucirumab to Docetaxel in Stage IV NSCLC

In the phase III REVEL trial reported in Lancet, Edward B. Garon, MD, of the David Geffen School of Medicine at UCLA/Translational Research in Oncology–US Network, Los Angeles, and colleagues found that the addition of the antiangiogenic vascular endothelial growth factor receptor (VEGFR)-2...

supportive care

CancerCare® Awarded $1.5 Million Grant From Susan G. Komen®

CancerCare, a leading national nonprofit organization providing free, professional support services to anyone affected by cancer, has received a $1.5 million grant to assist people diagnosed with breast cancer. The grant will support a CancerCare program in partnership with Susan G. Komen called...

cns cancers
gynecologic cancers
lung cancer

Aldoxorubicin Receives FDA Orphan Drug Designations for Glioblastoma, Small Cell Lung Cancer, and Ovarian Cancer

The U.S. Food and Drug Administration has granted Orphan Drug Designations to aldoxorubicin in three indications: glioblastoma multiforme, small cell lung cancer, and ovarian cancer. Aldoxorubicin combines doxorubicin with a novel single-molecule linker that binds directly and specifically to...

cns cancers

FDA Grants Orphan Drug Designation to Bivalent Vaccine for Neuroblastoma

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to MabVax Therapeutics’ vaccine for the treatment of relapsed or recurrent high-risk neuroblastoma in remission or with limited residual disease after best available treatment. The bivalent vaccine is intended to elicit ...

breast cancer

Aron Goldhirsch, MD, Receives 2014 Gianni Bonadonna Breast Cancer Award

Aron Goldhirsch, MD, was presented with the 2014 Gianni Bonadonna Breast Cancer Award and Lecture during the 2014 Breast Cancer Symposium, held recently in San Francisco. Dr. Goldhirsch is Director of the Multidisciplinary Program of Senology and Deputy Scientific Director at the European Institute ...

Expert Point of View: William M. Sikov, MD

At the Breast Cancer Symposium, William M. Sikov, MD, Associate Professor of Medicine at the Warren Alpert Medical School of Brown University, Providence, Rhode Island, gave a talk on the use of pathologic complete response in the clinic and summarized the CTNeoBC findings for The ASCO Post. “The...

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