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issues in oncology

Cancer-Specific Urgent Care Center: Effect on Emergency Department Use and Hospitalization Rate

In a single-institution study reported in JCO Oncology Practice, Gould Rothberg et al found that establishment of a dedicated cancer urgent care center within a large tertiary academic center resulted in a significant but modest decrease in emergency department use—but no significant reduction in...

covid-19

COVID-19 Pandemic Spurs Quick Uptick in Telehealth Adoption, ASCO Provides Guidance for Oncologists

ASCO recently released a new set of standards and practice recommendations specific to telehealth in oncology.1 These new standards provide guidance for which patients can be seen through telehealth; the establishment of the doctor-physician relationship; the role of allied health professionals and ...

gynecologic cancers
genomics/genetics

Prevalence of Germline BRCA Mutations in Indian Women With Ovarian Cancer

Ovarian cancer is one of the most common gynecologic cancers, with 313,959 new cases and 207,252 deaths reported worldwide in 2020.1 Since there is no effective screening method, ovarian cancer in general is diagnosed in its late stage. The 5-year survival rate in women with ovarian cancer is less...

gynecologic cancers
genomics/genetics

High Prevalence of Germline BRCA Mutations in Indian Women With Ovarian Cancer

In a prospective cross-sectional study reported in JCO Global Oncology, Sudeep Gupta, MBBS, MD, DM, of Tata Memorial Centre, and colleagues found that Indian women with ovarian cancer not selected for study based on clinical factors had a high prevalence of germline pathogenic or likely pathogenic...

cost of care

Pharmacy Strategy to Decrease Patient Copayments for High-Cost Cancer Drugs Through Financial Assistance Applications

In an observational retrospective study reported in JCO Oncology Practice, Seymour et al describe a strategy used by Karmanos Specialty Pharmacy (KSP) to successfully decrease patient copayments for high-cost cancer drugs. Study Details The study involved data from the KSP claims data set, accessed ...

covid-19

Teleoncology for Veterans With Cancer During the COVID-19 Pandemic

In a single-center study reported in JCO Oncology Practice, Jiang et al found an overall high level of satisfaction with teleoncology care during the COVID-19 pandemic among veterans with cancer in the United States, although a preference for in-person visits was commonly expressed. Teleoncology...

integrative oncology

Music Therapy for Cancer-Related Fatigue

Guest Editor’s Note: Despite the high prevalence of cancer-related fatigue, there are few effective management strategies for this debilitating condition. Music therapy is a nonpharmacologic modality that has been shown to reduce anxiety in oncology settings. In this installment of The ASCO Post’s...

pancreatic cancer
immunotherapy

Tackling the Challenge of Pancreatic Cancer: New Approaches

Pancreatic cancer remains an incorrigible foe, but recent advances in genomic profiling and targeted drug development are slowly improving the outlook for patients, according to Eileen M. O’Reilly, MD, Winthrop Rockefeller Endowed Chair in Medical Oncology and Section Head,...

issues in oncology

Association of Baseline Fatigue With Survival and Adverse Events in Patients With Advanced Cancer

In an analysis of four SWOG clinical trials of patients with advanced cancer reported in JCO Oncology Practice, Mo et al found that clinically significant fatigue at baseline was associated with poorer survival and increased risk of severe adverse events. Study Details The analysis included data...

issues in oncology
global cancer care

How Climate Change Is Impacting Cancer Care and What Can Be Done to Reduce Oncology’s Footprint on the Environment

Worldwide, the global average surface temperature has risen at a similar rate of 0.17°F per decade since 1901, with the warmest year on record occurring in 2016 and the second warmest occurring in 2020. However, according to NOAA, since the late 1970s, the United States has warmed faster than the...

ASCO Honors John V. Cox, DO, MBA, FACP, FASCO, With 2021 Joseph V. Simone Award

ASCO will recognize John V. Cox, DO, MBA, FACP, FASCO, a medical oncologist and professor at the University of Texas Southwestern, with the Joseph V. Simone Award and Lecture for Excellence in Quality and Safety in the Care of Patients With Cancer. Dr. Cox will be presented with the award at the...

gynecologic cancers

ASCO Publishes Resource-Stratified Guideline on Assessment and Treatment of Ovarian Cancer

Ovarian cancer carries a heavy morbidity and mortality burden, particularly in settings and regions of the globe that feature significant limitations in health-care resources. Given that ovarian cancer is more lethal than breast cancer, clinicians in resource-limited areas require guidance on the...

breast cancer

Breast Cancer in 2030: Predictions From a Breast Cancer Luminary

According to George W. Sledge, Jr, MD, FASCO, Professor of Medicine in the Division of Oncology at Stanford University Medical Center, by the beginning of the next decade, clinicians will be aided by the use of artificial intelligence (AI) in many facets of care and by the approval of a wave of new ...

kidney cancer

Oral Anticancer Agent Use in Patients With Metastatic Renal Cell Carcinoma

In a population-based cohort study reported in JCO Oncology Practice, Stephanie B. Wheeler, PhD, and colleagues found a low rate of oral anticancer agent use within 12 months after detection of metastatic disease in patients with renal cell carcinoma. Study Details The study used a novel, North...

issues in oncology

ASCO and COA Jointly Release Oncology Medical Home Standards

Today, ASCO and the Community Oncology Alliance (COA) jointly released new Oncology Medical Home (OMH) standards, which provide a comprehensive roadmap for oncology practices to deliver high-quality, evidence-based cancer care. These standards, which were published by Woofter et al in JCO Oncology...

breast cancer
global cancer care

Reflections on Evolution of Breast Cancer Care in India Over the Past 4 Decades

India has witnessed a major paradigm shift in the field of breast cancer and its management over the past 4 decades. The discipline of medical oncology has evolved exponentially over this period—a growth that few other scientific disciplines have experienced. Interventions at the individual,...

Efficiency of Virtual Care for Oncology Patients During the COVID-19 Pandemic

In a single-institution study reported in JCO Oncology Practice, Hsiehchen et al found that replacement of in-person with telehealth visits among patients with cancer initiating systemic therapy during the COVID-19 pandemic was not associated with poorer efficiency in components of oncology care or ...

New ASCO Journal Series Examines Disparities in Cancer Care for Black People in the United States

A new special series in JCO Oncology Practice explores the causes of disparities in cancer care and outcomes for Black people in the United States and examines potential solutions to begin to achieve health equity for this population. The “Disparities in Cancer Care for Black People in the United...

issues in oncology
survivorship

Addressing Sexuality Challenges Throughout the Cancer Care Continuum

Multiple studies have shown that sexuality and intimacy problems are common among patients with cancer, often beginning at the time of diagnosis and persisting through the continuum of care into the survivorship setting. Although these problems have been well documented, many patients and survivors ...

geriatric oncology

Do Community Oncologists Have Access to Geriatric Specialty Care for Older Patients?

As our population rapidly ages, the burden of cancer incidence increases accordingly, creating an urgent need for greater and more incisive research on the diagnosis, treatment, and survivorship issues for older adults with cancer. Given the numerous challenges faced by today’s busy oncologists, a...

gynecologic cancers
genomics/genetics
global cancer care

Prevalence of Germline BRCA Mutations in Women With Ovarian Cancer in India

In a prospective cross-sectional study reported in JCO Global Oncology, Gupta et al found that women with ovarian cancer in India had a high prevalence of pathogenic or likely pathogenic BRCA variants. As stated by the investigators: “There are deficient data on prevalence of germline mutations in...

issues in oncology

New Study Shows Difficulty in Identifying Transgender Individuals Using EHR Data

In order to understand and eliminate disparities in cancer incidence and outcomes among transgender people, clinicians and researchers must have data. However, these data are very difficult to obtain because gender identity data are not routinely collected in oncology practice health records. A new ...

Medical Oncologist Gouri Shankar Bhattacharyya, MD, FRCP, Dies of COVID-19–Related Complications

The members of the oncology community who spend time and energy addressing the growing global cancer burden in low- and middle-income countries have a kind of selfless dedication beyond the scope of the profession itself. One such medical oncologist was Gouri Shankar Bhattacharyya, MD, FRCP, a...

supportive care
issues in oncology

Lay Health Worker–Led Intervention May Improve Care for Low-Income and Minority Patients With Cancer

In a study reported in JCO Oncology Practice, Manali I. Patel, MD, MPH, and colleagues found that a lay health worker­–led intervention was associated with improved documentation of goals of care, increased clinical trial participation, and increased use of palliative care in a population of...

issues in oncology

Predictors of Emergency Department Visits After a New Diagnosis of Cancer

In a retrospective cohort study reported in JCO Oncology Practice, Hong et al found that prior frequent emergency department use was the strongest predictor of postdiagnosis emergency department visits among patients with a new diagnosis of cancer. Study Details The study involved data from adults...

immunotherapy

Use of Systemic Therapy at the End of Life in Patients With Cancer: Effect of Approval of Immunotherapies

In a study reported in JCO Oncology Practice, Khaki et al found that although the use of anticancer systemic therapy during the last 30 days of life in patients with cancer has decreased overall since the first approval of a PD-1 immune checkpoint inhibitor, the use of PD-1 or PD-L1 inhibitors...

issues in oncology

Equitable Cancer Care: Steps Toward Meaningful Change

As President-Elect of ASCO, you are asked to choose a theme for your presidency. This can be a daunting task, as the theme will not only shape the discourse of your presidency, but also, more importantly, that of the Society. The subject should be one that reflects the needs of the cancer community ...

colorectal cancer
genomics/genetics

Standard Multigene Testing Could Detect More Hereditary Cancer Syndromes in Patients With Colorectal Cancer

Up to 38.6% of people with colon cancer who have a hereditary cancer syndrome—including 6.3% of those with Lynch syndrome—could have their conditions remain undetected with current universal tumor-screening methods, and at least 7.1% of people with colorectal cancer have an identifiable inherited...

issues in oncology
health-care policy
legislation

Report Shows Medicaid Expansion Alone Does Not Resolve Disparities in Cancer Care

In the United States, Black and Latinx individuals have higher cancer mortality rates than patients of other races. Under the Patient Protection and Affordable Care Act (ACA) in 2014, many states expanded Medicaid eligibility, promising significant gains in coverage for racial minorities. But it...

supportive care
symptom management

Effect of Oral Chemotherapy Management Program on Capecitabine Toxicity

In a health system retrospective study reported in JCO Oncology Practice, Nhean et al found that implementation of an oral chemotherapy management program was associated with reduced rates of any-grade and severe capecitabine toxicity, less frequent toxicity-related emergency department visits and...

pain management
supportive care
issues in oncology

Oncologists’ Views on Challenges in Opioid Prescribing for Patients With Cancer-Related Pain

In an interview study reported in JCO Oncology Practice, Yael Schenker, MD, MAS, and colleagues identified challenges and measures for improvement cited by oncologists in the safe and effective prescribing of opioids for their patients with cancer-related pain. Study Details The investigators...

prostate cancer

Variations in Testing and Treatment Across Medical Specialties for Men Initiating Active Surveillance for Prostate Cancer

In a study reported in JCO Oncology Practice, Lai et al found that although the majority of men who have initiated active surveillance for prostate cancer are followed by urologists, some are managed by physicians in other specialties, and that testing and subsequent treatment patterns vary across...

geriatric oncology

Factors Associated With Unplanned Hospitalizations Among Older Patients Receiving Chemotherapy

In a study reported in JCO Oncology Practice, Klepin et al identified several factors associated with unplanned hospitalizations and hospital length of stay among patients with cancer aged 65 and older receiving chemotherapy. Study Details The study was a secondary analysis in a U.S. multisite...

integrative oncology
cost of care

Clinician Recommendations May Pique Patients’ Interest in Complementary and Integrative Therapies

Patients with cancer expressed more interest in complementary and integrative medicine services when these services were recommended by an oncologist or other medical professional or were provided for free in a clinical trial, according to a survey reported in JCO Oncology Practice.1 The survey...

integrative oncology
cost of care

How Interested Are Patients in Integrative Therapies, and How Much Are They Willing to Pay for Them?

The top two barriers to accessing complementary and integrative therapies, according to a survey of 576 patients with cancer and caregivers, were cost, cited by 56%, and a lack of knowledge about the therapies, cited by 52.1%. “Other barriers included a lack of time (29.2%), location of the...

Addressing Oncologist Burnout, Emotional Well-Being, and Moral Distress in the Pandemic

JCO Oncology Practice recently published an editorial that examines the intensified burnout oncology practitioners are experiencing due the COVID-19 pandemic and outlines critical interventions to support oncologists now and throughout a long-term recovery.1 The article was written by past,...

global cancer care
gynecologic cancers

Increasing Cervical Cancer Prevention and Care in Nepal

A new JCO Global Oncology special article details the process and results of a Multidisciplinary Cervical Cancer Prevention Course that ASCO volunteers led in Nepal, where cervical cancer remains the most common cancer among women and most patients present with an advanced stage of the disease.1...

genomics/genetics
lung cancer

Patient Knowledge and Expectations Regarding Genomic Testing Results

As reported in JCO Oncology Practice by Roth et al, many participants in a biomarker-driven master protocol trial (Lung Cancer Master Protocol [Lung-MAP]; SWOG S1400GEN) did not display correct knowledge or expectations about using the results of genomic testing. Study Details Lung-MAP is a...

skin cancer
immunotherapy
symptom management

Adverse Events in Patients With Melanoma Treated With Ipilimumab: Results of a Toxicity Monitoring Program

In a single-institution study reported in JCO Oncology Practice, Menjak et al found that a nurse-led telephone surveillance program for toxicity associated with ipilimumab in patients with metastatic melanoma led to earlier identification of toxicities and earlier intervention, with an apparent...

issues in oncology

Inpatient Radiation Oncology Consult Model for Metastatic Cancer to Reduce Hospital Length of Stay

In a single-institution study reported in JCO Oncology Practice, Xu et al found that implementation of a novel inpatient radiation oncology consult service was associated with a significant increase in consults involving metastatic disease specialists, as well as a reduction in hospital length of...

breast cancer
covid-19

Impact of COVID-19 Pandemic on Delivery of Breast Cancer Care in New York

In a single-institution retrospective study focused on a New York City location reported in JCO Oncology Practice, Satish et al found that more than 40% of patients with breast cancer not infected with COVID-19 had a delay or change in care delivery due to the pandemic. Study Details The study...

colorectal cancer

Molecular Testing in Metastatic Colorectal Cancer: Understanding How, When, and What to Profile

“In line with the emergence of targeted therapies, molecular biomarker testing in metastatic colorectal cancer has evolved over the past decade,” noted Jeanne Tie, MD, MBChB, FRACP, who acknowledged there is confusion about the best ways to use molecular testing in the clinic. Dr. Tie, who is...

breast cancer
covid-19

Time to Treatment Initiation for Breast Cancer During the COVID-19 Pandemic: Single-Institution Study

In a single-institution study reported in JCO Oncology Practice, Hawrot et al found that there was no increase in time to treatment initiation after histologic diagnosis in patients with newly diagnosed breast cancer during the first wave of the COVID-19 pandemic in 2020. However, they did find...

issues in oncology
prostate cancer

Patient Refusal of Provider-Recommended Locoregional Treatment for Prostate Cancer: Sociodemographic Factors

In a study reported in JCO Oncology Practice, Dee et al found that the rate of refusal of provider-recommended locoregional treatment for localized prostate adenocarcinoma has increased over time, with Black and Asian men with intermediate- or higher-risk disease being more likely to refuse such...

colorectal cancer
survivorship

Use of Chemotherapy and Risk of Alzheimer’s Disease in Colorectal Cancer Survivors

In a retrospective cohort study reported in JCO Oncology Practice, Akushevich et al found that receipt of chemotherapy was associated with a reduced risk of Alzheimer’s disease in colorectal cancer survivors. As stated by the investigators, “Evidence on the nature of the relationship between...

New Research Statement Recommends Streamlining and Standardizing Clinical Trial Site Feasibility Assessments

Feasibility assessments for clinical trials are conducted to establish that prospective trial sites can safely and effectively meet study goals and protocol requirements; however, a new research statement from ASCO asserts that current standards are “costly, inconsistent, inefficient, labor...

breast cancer
issues in oncology

Adherence to Adjuvant Hormonal Therapy Among Commercially Insured Women With Breast Cancer

In a study reported in JCO Oncology Practice, Zhao et al found that 5-year adherence to adjuvant hormonal therapy was low among commercially insured women with breast cancer in the United States. The retrospective observational study used data from the IBM MarketScan Research Databases to identify...

issues in oncology

New Framework to Address Cancer Care Disparities in Medically Underserved Populations

A new article published in JCO Oncology Practice puts forth a framework to guide researchers, health-care leaders, advocates, community- and patient-focused service organizations, and policy leaders in their work to address and promote health equity in cancer care access and treatment outcomes.1...

covid-19

COVID-19 and Cancer: A Toxic Combination

COVID-19 has caused 475,000 deaths in America, disproportionately among communities of color, poverty, immigrants, and older age. It has exposed a variety of inequities within our health-care system. However, the patients at greatest risk of death from COVID-19 are those with cancer. While 1.8% of...

covid-19

How the COVID-19 Pandemic Can Help Improve Cancer Research

The ripple effects of the coronavirus pandemic have been felt in every area of health care. In our medical specialty, oncology, clinical trials of new treatments were upended by COVID-19. In the early months of the pandemic, widespread interruptions in trial enrollment prevented some patients...

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