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AACR Inaugurated New Leadership at 2019 Annual Meeting

The American Association for Cancer Research (AACR) inaugurated Elaine R. Mardis, PhD, as President for 2019–2020 during the 2019 AACR Annual Meeting. Dr. Mardis holds the Nationwide Foundation Endowed Chair in Genomic Medicine and is Co–Executive Director of the Institute for Genomic Medicine at...

hepatobiliary cancer

FDA Approves Ramucirumab for Hepatocellular Carcinoma

ON MAY 10, the U.S. Food and Drug Administration (FDA) approved ramucirumab (Cyramza) as a single agent for hepatocellular carcinoma in patients who have an alpha fetoprotein (AFP) level ≥ 400 ng/mL and have been previously treated with sorafenib. REACH-2 Trial APPROVAL WAS based on the REACH-2...

NCCN Recognizes Five Individuals for Achievements in Cancer Care

THE NATIONAL Comprehensive Cancer Network® (NCCN®) has announced the recipients of a series of awards honoring individuals whose contributions have fueled progress in improving and facilitating quality, effective, efficient, and accessible cancer care over the past year. They are Timothy J....

Pancreatic Cancer Collective Funds Two Research Teams Using AI to Identify High-Risk Populations

THE PANCREATIC Cancer Collective, which is the strategic partnership of the Lustgarten Foundation and Stand Up To Cancer (SU2C), recently announced that it has awarded $1 million grants to each of 2 projects that are using artificial intelligence (AI) computational approaches to identify high-risk...

City of Hope Awarded $7.5 Million for Research in Cutaneous T-Cell Lymphoma

CITY OF HOPE recently received $7.5 million in grant awards to study the rare blood cancer cutaneous T-cell lymphoma. The National Cancer Institute (NCI) awarded two grants valued at $6.3 million over 5 years to City of Hope’s Steven Rosen, MD, and Christiane Querfeld, MD, PhD, so they can develop...

pain management
health-care policy

Debating the Role of Opioids in the Management of Chronic Cancer Pain

Despite the increasing public awareness of the danger of the overuse of prescription opioids, drug overdose deaths continue to rise in the United States. According to the Centers for Disease Control and Prevention (CDC), from 1999 to 2017, nearly 400,000 people died of an overdose involving...

Andrew T. Chan, MD, MPH, Receives 2019 AACR–Waun Ki Hong Award

The American Association for Cancer Research (AACR) recently awarded Andrew T. Chan, MD, MPH, with the 2019 AACR–Waun Ki Hong Award for Outstanding Achievement in Translational and Clinical Cancer Research during the 2019 AACR Annual Meeting. Dr. Chan is recognized for his work on the molecular...

Miami Cancer Institute Opens Multidisciplinary Skin Cancer Clinic

Miami Cancer Institute has announced the opening of its Multidisciplinary Skin Cancer Clinic, along with the region’s first three-dimensional (3D), whole-body, photo-imaging system, designed to improve the accuracy of diagnosing melanoma and other skin cancers. This system is reportedly 1 of 12...

USC Norris Comprehensive Cancer Center Appoints Caryn Lerman, PhD, as Director

Caryn Lerman, PhD, has been appointed Director of the USC Norris Comprehensive Cancer Center, also serving as Professor of Psychiatry and the Behavioral Sciences. Prior to this appointment, Dr. Lerman was the John H. Glick Professor for Cancer Research and Vice Dean for Strategic Initiatives in...

Margaret Foti, PhD, MD (hc), Receives 2019 Women of Inspiration and Influence Award

Women Business Leaders (WBL), of the U.S. Health Care Industry Foundation, recently recognized American Association for Cancer Research (AACR) Chief Executive Officer Margaret Foti, PhD, MD (hc), with the 2019 Women of Inspiration and Influence award. Dr. Foti is among 11 senior executive women...

issues in oncology
gynecologic cancers
global cancer care

Barriers to Cervical Cancer Screening Among HIV-Infected Women in Tanzania

Population screening programs and the advent of human papillomavirus (HPV) vaccination have made cervical cancer largely a preventable disease. Despite these advances, ­cervical cancer remains a leading cause of cancer death for ­women in low- and middle-income countries. A recent study identified...

integrative oncology

Capsaicin

The ASCO Post’s Integrative Oncology series is intended to facilitate the availability of evidence-based information on integrative and complementary therapies sometimes used by patients with cancer. In this installment, Shelly Latte-Naor, MD, and Jyothirmai Gubili, MS, explore the use of...

Francoise Mornex, MD, PhD, Named First Female Recipient of Heine H. Hansen Award

The European Society for Medical Oncology (ESMO) and the International Association for the Study of Lung Cancer (IASLC) recently awarded the 2019 Heine H. Hansen Award to Francoise Mornex, MD, PhD. The award was presented at the 2019 European Lung Cancer Congress. Dr. Mornex is Professor of...

global cancer care

Measuring the Burden of Global Cancer as a Tool for Policymakers

The Global Burden of Disease Study was initiated in 1990, commissioned by the World Bank. At that time, the study was conducted mainly by researchers at Harvard and the World Health Organization (WHO). Since then the study has gone through many iterations to its present structure, which is a...

NIH Selects Three Oncology Investigators as Lasker Clinical Research Scholars

The National Institutes of Health (NIH) has selected eight scientists as Lasker Clinical Research Scholars as part of a joint initiative with the Albert and Mary Lasker Foundation to foster the next generation of clinical scientists. This program provides early-stage researchers with the...

global cancer care

Uniting the Global Cancer Community to Reduce Deaths From Noncommunicable Diseases

It has been well documented that noncommunicable diseases, including cancer, cardiovascular disease, and diabetes, now pose the greatest health threat to people living in low- and middle-income countries, surpassing infectious diseases like HIV/AIDS as the leading cause of death and disability.1...

Margo Shoup, MD, FACS, Appointed Network Chair of Nuvance Health Cancer Service Line

Margo Shoup, MD, FACS, has been appointed Network Chair of the Cancer Service Line for the new health system formed by Health Quest and Western Connecticut Health Network (WCHN), to be called Nuvance Health. Dr. Shoup will provide strategic and clinical leadership for all aspects of Nuvance...

Pat A. Basu, MD, MBA, Named President and Chief Executive Officer of Cancer Treatment Centers of America

Pat A. Basu, MD, MBA, has been appointed President and Chief Executive Officer of Cancer Treatment Centers of America Global, Inc., which includes the existing Comprehensive Cancer Care Network of Cancer Treatment Centers of America® (CTCA) hospitals and outpatient care centers, as well as new...

AACR Honors Elaine Fuchs, PhD, With 2019 AACR G.H.A. Clowes Memorial Award

The American Association for Cancer Research (AACR) has awarded the 59th AACR G.H.A. Clowes Memorial Award to Elaine Fuchs, PhD. The award was presented during the AACR Annual Meeting 2019. Dr. Fuchs delivered her award lecture, “Stem Cells in Wound Repair, Inflammation, and Cancer,” at the Georgia ...

ASH President Comments on Medicare Proposal for CAR T-Cell Therapy

Recently, the Centers for Medicare & Medicaid Services (CMS) proposed to improve the reimbursement currently given to hospitals that provide chimeric antigen receptor (CAR) T-cell therapy to patients with blood cancer as part of the Fiscal Year 2020 Inpatient Prospective Payment System...

global cancer care
issues in oncology

St. Jude Children’s Research Hospital and WHO Join Forces to Improve Childhood Cancer Survival Worldwide

A report by the International Agency for Research on Cancer (IARC) based on data from more than 100 cancer registries in 68 countries shows that from 2001 to 2010, the occurrence of childhood cancer worldwide was 13% more common than in the 1980s.1 In addition, the report’s findings showcase stark...

Teen Cancer America Announces New Advisory Council

Teen Cancer America (TCA), the national nonprofit organization founded by rock artists Roger Daltrey and Pete Townshend of The Who, recently announced appointments to its newly formed Advisory Council. Based in Los Angeles, TCA develops specialized facilities as well as treatment- and age-specific...

issues in oncology
cost of care
survivorship

How Cancer Affects Adolescents and Young Adults

The statistics are alarming: according to the National Cancer Institute (NCI), about 70,000 adolescents and young adults (AYAs) are diagnosed with cancer each year1—a recent report by the University of California put that figure at 87,000.2 Although overall cancer survival rates continue to improve ...

prostate cancer

New Radiation Options for Localized Prostate Cancer May Improve Patient Outcomes

External-beam radiation therapy (EBRT) is a standard treatment option for men with localized prostate cancer and confers long-term prostate cancer control outcomes equal to radical prostatectomy. Technologic advances in imaging and computing during the past 20 years have led to a number of...

Charles G. Mullighan, MBBS (Hons), MSc, MD, Named St. Jude Comprehensive Cancer Center Deputy Director

The St. Jude Children’s Research Hospital Comprehensive Cancer Center has appointed Charles G. Mullighan, MBBS (Hons), MSc, MD, as its new Deputy Director. In this new position, Dr. Mullighan will help guide precision medicine and preclinical strategic research initiatives for the Center, which is...

Anjali Mishra, PhD, and Nitin Chakravarti, PhD, Join Sidney Kimmel Cancer Center at Jefferson Health

The Sidney Kimmel Cancer Center–Jefferson Health (SKCC) recently welcomed Anjali Mishra, PhD, and Nitin Chakravarti, PhD, to its team of researchers focused on hematologic cancers. Both Drs. Mishra and Chakravarti are Assistant Professors in the Department of Medical Oncology. Dr. Mishra is a...

Lisa Kachnic, MD, Joins Columbia University as Chair of Radiation Oncology

Lisa Kachnic, MD, has been named Chair of the Department of Radiation Oncology at the Columbia University Vagelos College of Physicians and Surgeons and Chief of the Radiation Oncology Service at NewYork-Presbyterian/Columbia University Irving Medical Center. She will also serve as Associate...

hematologic malignancies
leukemia
lymphoma

FDA Approves Chemotherapy-Free Regimen, Venetoclax Plus Obinutuzumab, as First-Line Treatment for CLL/SLL

On May 15, the U.S. Food and Drug Administration (FDA) approved venetoclax (Venclexta) in combination with obinutuzumab (Gazyva) for the treatment of adult patients with previously untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Approval was based on the CLL14...

lung cancer

FDA Expands Pembrolizumab Indication for NSCLC in First-Line Setting

On April 14, the U.S. Food and Drug Administration (FDA) approved pembrolizumab (Keytruda) for the first-line treatment of patients with stage III non–small cell lung cancer (NSCLC) who are not candidates for surgical resection or definitive chemoradiation, or those with metastatic NSCLC....

AIM at Melanoma Foundation Opens First Melanoma Tissue Bank in the United States

The AIM at Melanoma Foundation recently announced the grand opening of the first branch of the International Melanoma Tissue Bank Consortium (IMTBC) at the Hillman Cancer Center, University of Pittsburgh Medical Center (UPMC). The Pittsburgh site is the first of six global locations of the...

Baylor Scott & White Health Names New Chief of Oncology, Ronan Kelly, MBBCh, MD, MBA

Baylor Scott & White Health, the largest not-for-profit health-care system in Texas, recently named Ronan Kelly, MBBCh, MD, MBA, Chief of Oncology for the organization’s North Texas medical centers. Dr. Kelly’s leadership will span Baylor University Medical Center—the System’s North Texas...

hematologic malignancies
leukemia

FDA Approves First-Line Ivosidenib for IDH1-Mutated AML

On May 2, the U.S. Food and Drug Administration (FDA) expanded its approval of ivosidenib (Tibsovo) to include newly diagnosed acute myeloid leukemia (AML) with a susceptible IDH1 mutation, as detected by an FDA-approved test, in patients who are at least 75 years old or who have comorbidities that ...

hematologic malignancies
lymphoma

Combination Immunotherapy With Lenalidomide Plus Rituximab in Indolent NHL: Time to Replace Rituximab Monotherapy?

With increasing knowledge on the key role of the tumor microenvironment in lymphomagenesis, treatments for indolent B-cell lymphoma, especially follicular lymphoma, are mechanistically moving toward a more immunomodulatory approach. Chemotherapy-free regimens are an attractive alternative to...

Dana-Farber Opens New Center for Patients With Lynch Syndrome

Dana-Farber Cancer Institute recently announced the opening of the first Lynch Syndrome Center dedicated to providing genetic counseling and testing for those at risk for the syndrome and delivering a new model of coordinated care for those living with the disease. A common and underdiagnosed...

Jonas Bergh, MD, PhD, FRCP, Receives First ESMO Breast Cancer Award

The European Society for Medical Oncology (ESMO) announced recently that Jonas Bergh, MD, PhD, FRCP, of the Karolinska Institutet in Stockholm, has been awarded the newly established 2019 ESMO Breast Cancer Award at the inaugural ESMO Breast Cancer Congress 2019. The ESMO Breast Cancer Award...

Gareth Morgan, MD, PhD, and Faith Davies, MD, Join New Center for Blood Cancers at NYU Langone Health

Hematology experts Gareth Morgan, MD, PhD, and Faith Davies, MD, have joined the Center for Blood Cancers at NYU Langone Health’s Perlmutter Cancer Center and will lead its multiple myeloma program. About Dr. Morgan Dr. Morgan, the Center’s Director of Multiple Myeloma Research, previously served...

City of Hope Announces Faculty Awards

Over the past year, in recognition of their research and dedication to treating patients with cancer, several physician-scientists from City of Hope received awards, fellowships, and honor society inductions. These recipients listed below are experts in a variety of cancers and treatments, ranging...

issues in oncology

2019 NCCN Posters Explore Next-Generation Sequencing, Cancer Burden vs Funding, Cardiac Monitoring, and Scalp Cooling

Posters presented at the National Comprehensive Cancer Network® (NCCN®) Annual Conference continue to grow in number and in quality. The ASCO Post presents a few that we found interesting at the recent 2019 meeting. Next-Generation Sequencing Not Always Helpful in Practice The value of...

hematologic malignancies

Prolonged Exposure to Ibrutinib May Increase Effectiveness of CAR T-Cell Therapy in Patients With CLL

Chimeric antigen receptor (CAR) T-cell therapy has shown remarkable efficacy in the treatment of certain hematologic malignancies, including several types of large B-cell non-Hodgkin lymphomas (NHLs) and acute lymphoblastic leukemia (ALL). The U.S. Food and Drug Administration (FDA) has approved...

breast cancer

Risk of Breast Cancer Among Transgender People

In a Dutch study published by de Blok et al in The BMJ, researchers found an increased risk of breast cancer in transgender women compared with cisgender men, and a lower risk of breast cancer in transgender men than in cisgender women. Methods This retrospective, nationwide cohort study...

issues in oncology

Introducing CancerLinQ® 2.0 and a New Era in Precision Oncology

In just 5 years since its launch in 2014, CancerLinQ®, ASCO’s big-data, rapid-learning, health information technology platform, has grown from 37 vanguard oncology practices to 58 participating practices in 2016 to 100 diverse oncology practices nationwide this year. CancerLinQ...

prostate cancer

Prostate-Only vs Whole-Pelvis Radiotherapy in Gleason Grade 5 Prostate Cancer

In a retrospective analysis published in European Urology, Sandler et al examined the protocol for treating aggressive prostate cancer. Researchers aimed to study the impact of whole-pelvis radiation on men with Gleason grade 5 disease who had been treated with external-beam radiotherapy with...

colorectal cancer
survivorship

Factors Associated With Major Adverse Cardiovascular Events in Survivors of Colorectal Cancer

Colorectal cancer survivors’ risk for heart attack—five times that of the average person—may be linked to the amount of fat stored within the abdomen and abdominal muscles, not to body mass index (BMI), according to a new study of 2,800 colon cancer survivor health outcomes...

issues in oncology
legislation

Members of Congress Express Support for Cancer Policy Priorities During Capitol Hill Event

ASCO and the American Cancer Society Cancer Action Network (ACS CAN) hosted a reception on Capitol Hill for Members of Congress and their staff to underscore the two organizations’ shared policy priorities to improve research and cancer care delivery for patients and survivors. During the...

issues in oncology

ASCO Announces New Task Force to Address Rural Cancer Care Gap

ASCO recently announced a new task force aimed at reducing disparities and improving outcomes for patients and survivors of cancer who live in rural communities. The new Rural Cancer Care Task Force will identify opportunities to close the rural cancer care gap and implement strategies to improve...

Help Your Patients Catch Up on the Latest Research From the 2019 ASCO Annual Meeting With Cancer.Net

The Cancer.Net blog (accessible at cancer.net/blog) features daily posts covering research highlighted at the 2019 ASCO Annual Meeting. Patients and caregivers can learn what this research means for their care and treatment. The Cancer.Net blog also offers continuing coverage from the ASCO Annual...

Four Reasons to Use Social Media at the ASCO Annual Meeting

Join the discussion: Use #ASCO19 on Twitter and Instagram to follow and participate in conversations about the ASCO Annual Meeting in real time. During last year’s ASCO Annual Meeting, more than 17,000 health-care professionals, researchers, news outlets, patients, and advocates sent more than...

Researchers Supported by Conquer Cancer, the ASCO Foundation, Earn Spot in Clinical Cancer Advances 2019

The work of nine researchers who have previously received funding from Conquer Cancer is featured in ASCO’s Clinical Cancer Advances 2019. Visit CONQUER.ORG/CCA for more details. In two separate trials, Conquer Cancer–supported investigators produced research results that improved treatment for...

lung cancer

Two Prominent Lung Cancer Organizations Join Forces to Launch GO2 Foundation for Lung Cancer

Two of the nation’s leading lung cancer organizations—the Bonnie J. Addario Lung Cancer Foundation (ALCF) and the Lung Cancer Alliance (LCA)—announced in April their merger to form the GO2 Foundation for Lung Cancer. The new organization, which has offices in Washington, DC, and the San Francisco...

Access ASCO’s Quality Programs to Accelerate Quality Care Delivery in Your Practice

Improve the care your practice provides by participating in ASCO’s wide array of quality improvement programs. ASCO’s Quality Oncology Practice Initiative (QOPI®) is an oncologist-led, practice-based quality assessment program designed to promote excellence in cancer care by helping practices...

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