Search Results
Your search for ASCO matches 21353 pages
Showing 19051 - 19100Understanding the Role of Immune Function in the Treatment of HER2-Positive Breast Cancer
The addition of trastuzumab (Herceptin) to adjuvant chemotherapy undoubtedly transformed HER2-positive breast cancer from one of the most deadly subtypes to a highly treatable disease. Randomized phase III trials established adjuvant trastuzumab as standard of care in HER2-positive breast...
Clinical Trial Participation: ‘Is It All Worth It?’
Clinical trials have become increasingly complex over the past several years, and unfortunately, this has resulted in the typical scenario described below. We are fortunate that there are so many promising agents available for patients, and we want to encourage their participation in clinical...
No Survival Benefit From Adjuvant Sorafenib or Sunitinib in Kidney Cancer
Adjuvant therapy with sorafenib (Nexavar) or sunitinib (Sutent) failed to make any inroads in improving disease-free survival in patients with locally advanced kidney cancer in the randomized, placebo-controlled, multicenter, phase III Adjuvant Sorafenib and Sunitinib for Unfavorable Renal...
The ASCO Post Replies
Nivolumab (Opdivo) was approved by the U.S. Food and Drug Administration (FDA) for the treatment of lung cancer on March 4, 2015, before clinical data from the pivotal trials (CheckMate 017 and CheckMate 063) were presented at a major oncology conference or published in a peer-reviewed journal....
Nivolumab in Lung Cancer
I find The ASCO Post to be a good way to hear about new ideas that I might otherwise have missed. I read an article recently about the approval of nivolumab (Opdivo) for treating metastatic squamous non-small cell lung cancer (The ASCO Post, April 10, 2015). I thought it would have been much more...
Widespread Use of Docetaxel Preceded Phase III Evidence of Usefulness in Patients With Metastatic Prostate Cancer
Docetaxel was being widely used by patients with metastatic prostate cancer before phase III evidence that it was more effective than the standard of care for patients with castration-resistant prostate cancer, according to an analysis of Medicare claims from before and after the trial results and...
Expect Questions About Cold Caps to Spare Hair During Chemotherapy
For patients who have confronted a diagnosis of cancer, then endured weeks of chemotherapy, it would seem that losing their hair would not be a big concern. But for many patients, it can be. “You have to spend a year either putting on wigs or announcing to the world that you’ve had chemotherapy,”...
Scalp Cooling Caps Offer Option to Prevent Hair Loss During Chemotherapy
Hair loss remains one of the most dreaded side effects of chemotherapy, particularly for women. Scalp cooling caps worn by patients during chemotherapy infusion and for brief periods of time before and after offer these patients an option to preserve 50% or more of the hair on their heads. Although ...
2015 Canada Gairdner Awards Honor Top Medical Researchers Worldwide
The Gairdner Foundation named the winners of the 2015 Canada Gairdner Awards, recognizing some of the most significant medical discoveries around the world. The awards provide a $100,000 (CAD) prize to each scientist for his or her work. The aim of the Gairdner Awards is to promote a culture of...
2015 Oncology Meetings
MAY International Society of Geriatric Oncology (SIOG): Cancer Care of the Older Adult Across the Cancer ContinuumMay 1 • New York, New York For more information: www.siog.org 1st Annual New Treatments in Oncology Conference (ANTO)May 1-2 • Scottsdale, Arizona For more information:...
Patient Guides Available Through ASCO University Bookstore
ASCO Answers: Managing the Cost of Cancer Care explains the various costs associated with cancer treatment, including health-care coverage through the Affordable Care Act. It also provides a list of financial resources available to help offset expenses related to care and tips for organizing...
AACR Honors Cancer Pioneers at the 2015 Annual Meeting
The American Association for Cancer Research (AACR) recognized six oncologists making valuable contributions to their fields with awards at the Association’s Annual Meeting 2015, held in Philadelphia from April 18–22. William C. Hahn, MD, PhD, was awarded with the 39th Annual AACR–Richard and Hinda ...
Lewis C. Cantley, PhD, Honored With AACR Memorial Lectureship
The American Association for Cancer Research (AACR) honored Lewis C. Cantley, PhD, with the 9th Annual Princess Takamatsu Memorial Lectureship at the AACR Annual Meeting 2015. Dr. Cantley is the Meyer Director of the Sandra and Edward Meyer Cancer Center, the Margaret and Herman Sokol Professor in...
Dana-Farber President and CEO Edward J. Benz, Jr, MD, to Retire in 2016
Dana-Farber President and CEO Edward J. Benz, Jr, MD, has announced he will retire from the Dana-Farber Cancer Institute (DFCI) in 2016, after 16 years running the organization. Dr. Benz will also vacate the positions as Director and Principal Investigator of the Dana-Farber/Harvard Cancer Center...
Robert H. Lurie Names Associate Director for Administration
Aleksandar Zafirovski, MBA, has been named Executive Administrative Director and Associate Director for Administration for the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. He has served as Interim Associate Director since 2014. Mr. Zafirovski has previously been...
Richard Gilbertson, MD, PhD, Leaves St. Jude Children’s Research Hospital
St. Jude Children’s Research Hospital announced the departure of Scientific and Comprehensive Cancer Center Director, Richard Gilbertson, MD, PhD. Dr. Gilbertson will be Director of the Cambridge Cancer Centre at the University of Cambridge. Since joining St. Jude in 2000, Dr. Gilbertson has led...
Recipients of the 2015 Conquer Cancer Foundation’s Innovation Grants
The Conquer Cancer Foundation’s 2015 International Innovation Grants were awarded to the following five organizations conducting research in India, Mexico, Nigeria, Romania, and Uganda: Tata Medical Center (Kolkata, India). This grant is funding a randomized clinical study testing the success of...
Owen N. Witte, MD, Recognized With AACR G.H.A. Clowes Memorial Award
The American Association for Cancer Research (AACR) honored Owen N. Witte, MD, Founding Director of the Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, and Distinguished Professor of Microbiology, Immunology, and Molecular Genetics at the University of California,...
FDA Grants Priority Review to Carfilzomib Supplemental New Drug Application for Relapsed Multiple Myeloma
The U.S. Food and Drug Administration (FDA) has accepted Amgen’s supplemental New Drug Application (sNDA) for carfilzomib (Kyprolis) injection for the treatment of patients with relapsed multiple myeloma who have received at least one prior therapy. The sNDA is designed to support the conversion of ...
FDA Grants Breakthrough Therapy Designation to Rucaparib in Advanced Ovarian Cancer With BRCA Mutations
The U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to Clovis Oncology’s investigational agent rucaparib as monotherapy treatment of advanced ovarian cancer in patients who have received at least two lines of prior platinum-containing therapy, with BRCA-mutated ...
Ann Partridge, MD, MPH, Confronts Challenges Facing Young Women With Breast Cancer With Support From Conquer Cancer Foundation Improving Cancer Care Grant
Ann Partridge, MD, MPH, Associate Professor of Medicine at Harvard Medical School and Founding Director of the Program for Young Women With Breast Cancer at the Dana-Farber Cancer Institute, received a 2010 Improving Cancer Care Grant (ICCG) for her project “Improving the Care of Young Women with...
ASCO’s Oncology Interoperability Standard Highlighted in AMIA’s Bioinformatics Journal Club Webinar
ASCO’s oncology-specific interoperability electronic data-sharing standard for communicating and coordinating care throughout the cancer journey was featured in the American Medical Informatics Association’s Bioinformatics Journal Club webinar, a live production jointly sponsored by the Division of ...
FDA’s Biosimilar Product Approval Process: A Closer Look
In March, the U.S. Food and Drug Administration (FDA) approved filgrastim-sndz (Zarxio) as a biosimilar to U.S.-licensed filgrastim (Neupogen). It is the first biosimilar product to be approved in the United States and will increase treatment options for people living with cancer. The FDA considers ...
Researcher Spotlight on Conquer Cancer Foundation International Innovation Grant Recipient Mya Thida, MBBS
In 2014, Mya Thida, MBBS, of Myanmar, was awarded one of the first-ever Conquer Cancer Foundation of ASCO International Innovation Grants. This grant was created to fund novel research projects that may significantly improve cancer control in low- and middle-income countries. One year later, Dr....
Cancer Control in Primary Care Courses Offered in India
ASCO International’s mission is to optimize care for every patient with cancer in the world. To achieve that goal, it is critical to establish collaborations in all sectors of the health-care system. ASCO International’s newest course, Cancer Control in Primary Care, helps to address this need by...
Direct Your Patients to Cancer.Net for Informative Videos
Cancer.Net offers patient-friendly videos produced by ASCO to give people with cancer and their families and friends an additional option for oncologist-approved information. Topics covered include side effects, treatments, tests and procedures, quality of life, survivorship, cancer research news,...
Triple Negative Breast Cancer Foundation Works to Change the Treatment Landscape of an Aggressive Form of Breast Cancer
Hayley Dinerman, Cofounder and Executive Director of the Triple Negative Breast Cancer Foundation, remembers how she and a group of close female friends first learned about the devastating effects of triple-negative breast cancer. It was 2005 when these new mothers, who had recently formed a...
Michael E. Jung, PhD, Charles Sawyers, MD, and Howard I. Scher, MD, Receive Team Science Award From American Association for Cancer Research
Michael E. Jung, PhD, Distinguished Professor of Chemistry and Biochemistry and Member at UCLA Jonsson Comprehensive Cancer Center; Charles Sawyers, MD, Human Oncology and Pathogenesis Program Director at Memorial Sloan Kettering Cancer Center; and Howard I. Scher, MD, Chief of the Genitourinary...
Preparing for the ‘Silver Tsunami’ and the Impact of an Aging Population on Cancer Care
“Older adults constitute the only increasing natural resource in the entire world.” —Linda Fried, PhD, Columbia School of Public Health The good and bad news about our changing demographic world is that the population of older adults is increasing in the United States and worldwide. While it is...
In Search of ‘Just’ Prices: Questioning the High Cost of New Cancer Drugs
As the oncology community begins the slow and often difficult-to-define transition from volume to value in the delivery of cancer care, the relationship between the price and value of certain high-priced cancer drugs is getting more scrutiny. We generally correlate the efficacy of a new drug and...
Aspirin as Adjuvant Therapy for Colon Cancer: Is the Time Right?
Aspirin has long proved to be a multipotent drug, with efficacy as a pain reliever, anti-inflammatory agent, antiplatelet agent, and cardioprotective agent. In the cancer world, a large literature has accumulated demonstrating its ability to prevent various epithelial malignancies, most notably...
Breast Cancer Management in Review
With the field of breast oncology as complex as ever, a brief update of the latest findings impacting breast cancer treatment seems timely. To that end, I have assembled highlights from a collection of newsworthy studies featured over the past year and into early 2015. Part 1 of this review, which...
Richard Pazdur, MD, and Anthony S. Fauci, MD, Included in Fortune’s List of the World’s 50 Greatest Leaders
Richard Pazdur, MD, Director of the Office of Oncology and Hematology Products at the U.S. Food and Drug Administration (FDA) was named one of the world’s 50 greatest leaders by Fortune Magazine. The list also included names such as Pope Francis, Apple CEO Tim Cook, Chief Justice of the United...
Overweight Girls Face Increased Risk of Colorectal Cancer Later in Life
Girls who are overweight as young children and teens may face increased risk for colorectal cancer decades later, regardless of what they weigh as adults, suggests a new study published by Xuehong Zhang, MD, ScD, Instructor at Harvard Medical School, and colleagues in Cancer Epidemiology,...
Opioid-Reduction Strategy for Postoperative Pain After Breast Cancer Surgery
One persistent and potentially debilitating problem breast cancer patients suffer with is postoperative pain. Studies show that proper pain management is an essential component in the healing process, but undertreatment of pain symptoms remains an ongoing issue in the oncology community. Opioids,...
Should We Be Worried If Patients Tolerate Endocrine Therapy Well?
When meeting with patients to discuss adjuvant endocrine therapy for breast cancer, the question often arises, “How will I know that the treatment is working?” While the efficacy of these treatments has been demonstrated for the majority of patients in multiple large randomized clinical trials,...
Remembering Dr. Jane Weeks’ Pioneering Work and NCCN’s Outcomes Research Initiative
Jane Carrie Weeks, MD, MSc, a prominent researcher at Dana-Farber Cancer Center, died of cancer on September 10, 2013, at the age of 61. At the time of her death, Dr. Weeks was Professor of Medicine at Harvard Medical School, Professor of Health Policy and Management at the Harvard School of Public ...
20 Years of NCCN: The Best Is Yet to Come
As the National Comprehensive Cancer Network (NCCN) celebrates its 20th year, The ASCO Post asked its Chief Executive Officer, Robert W. Carlson, MD, to reflect on the organization’s accomplishments, mission, and future and on the role he may have played in its success. The Early Years You became...
How the International Innovation Grant Is Improving Cancer Care for Women in Myanmar
In 2014, the Conquer Cancer Foundation awarded four inaugural International Innovation Grants to aid novel research projects in Colombia, Myanmar, Nigeria, and Tanzania. The program, which supports a 1-year research grant of up to $20,000 to a nonprofit organization or governmental agency in a low- ...
Noncommunicable Diseases Are the Leading Cause of Death in Low- and Middle-Income Countries
The greatest health threat to people living in low- and middle-income countries is no longer infectious diseases like HIV/AIDS, which has seen a 33% decline in the global rate of new infections since 2001.1 It is the rise of noncommunicable diseases (including cancer, cardiovascular disease, and...
Heal Thy Patient … Reflections on the Human Side of Medicine
The first time I met Mrs. X and her husband was to discuss the surgical treatment options for pancreatic cancer. She had just been diagnosed with pancreatic cancer at her local hospital and was being referred to a tertiary care center for operative management. Mrs. X and her husband were no...
PRIME II and the Omission of Radiation Therapy in Low-Risk, Elderly Patients Undergoing Breast Conservation: The Time Has Come
Despite the high prevalence of breast cancer worldwide, it is important to recognize that > 40% of all cases occur in women aged 65 years or older in both the United States and the United Kingdom.1,2 Breast cancers in older patients are more often associated with indolent features and with...
Escalation of Oncology Services at End of Life May Be Moderated by Coordinated Care
“Use of oncology-related services is increasingly scrutinized, yet precisely which services are actually rendered to patients, particularly at the end of life, is unknown,” noted an article in the Journal of Oncology Practice. To address this knowledge gap, Eijean Wu, MD, of the Los Angeles County...
2015 Oncology Meetings
MAY 13th Annual Meeting of the Association for Cancer Immunotherapy (CIMT)May 11-13 • Mainz, Germany For more information: www.meeting.cimt.eu 54th Annual Conference of the Particle Therapy Co-Operative GroupMay 18-23 • San Diego, California For more information: http://ptcog54.org American...
Patient Guides Available Through ASCO University Bookstore
ASCO Answers: Managing the Cost of Cancer Care explains the various costs associated with cancer treatment, including health-care coverage through the Affordable Care Act. It also provides a list of financial resources available to help offset expenses related to care and tips for organizing...
Robert Coleman, MD, Begins SGO and Foundation Presidency
Robert L. Coleman, MD, Professor, Department of Gynecologic Oncology and Reproductive Medicine at The University of Texas MD Anderson Cancer Center, started his 1-year term as the 47th President of the Society of Gynecologic Oncology (SGO) and 5th President of the Foundation for Gynecologic...
FDA Approves Ramucirumab for Metastatic Colorectal Cancer
The U.S. Food and Drug Administration (FDA) today approved ramucirumab (Cyramza) for use in combination with FOLFIRI (leucovorin, fluorouracil, irinotecan) for the treatment of patients with metastatic colorectal cancer whose disease has progressed on a first-line bevacizumab (Avastin)-,...
Bombarded With Changes in Health Care and Beyond, Gynecologic Oncologists Prepare for the Challenges Ahead
Physicians are being “bombarded” with changes in health care and beyond, Richard R. Barakat, MD, FACS, noted in his Presidential Address at the Society of Gynecologic Oncology (SGO) Annual Meeting on Women’s Cancer. These changes are being precipitated by steeply rising health-care costs amid...
Conquer Cancer Foundation
Be on the lookout for a big announcement from the Conquer Cancer Foundation at the 2015 Annual Meeting. How will you be able to take part? By making a gift in support of vital cancer research, education, and tools to improve the quality of cancer care. Donations can be made online at ccf.asco.org,...
Maintenance of Certification Activities: Earn Points at the ASCO Annual Meeting
The 2015 ASCO Annual Meeting will feature three activities to help attendees earn American Board of Internal Medicine (ABIM) Maintenance of Certification (MOC) points while onsite. Annual Meeting Practice-Centered Session MOC Self-Assessment Activity This activity is designed for attendees who want ...
