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ECOG-ACRIN Group Co-Chair Robert L. Comis, MD, to Step Down in 2019

The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) announced that Robert L. Comis, MD, Professor of Medicine at Drexel University, is stepping down from his position as Group Co-Chair of the organization. His departure, effective February 28, 2019, will coincide with the end of ECOG-ACRIN’s current ...

New Appointments to Fox Chase Cancer Center Department of Medicine

Fox Chase Cancer Center recently announced two new appointments in its Department of Medicine. Christopher J. Manley, MD Christopher J. Manley, MD, has joined Fox Chase Cancer Center as the Director of Interventional Pulmonology in the Department of ­Medicine. “Dr. Manley’s expertise in pulmonary...

lymphoma

Electronic Health Record Data May Help Identify Older Patients at Highest Risk of Early Death From Chemotherapy for Diffuse Large B-Cell Lymphoma

Although diffuse large B-cell lymphoma (DLBCL) is a curable disease in most patients aged 65 years or older, these patients are also at higher risk of chemotherapy-related death within the first 30 days of treatment. To quantify the risk of early fatality and identify risk factors, researchers led ...

Oncologist’s Guilt

The best part of my day is hearing that little voice yell, “It’s ­Momma!” as my son rushes to greet me with a hug. It is humbling, and sometimes terrifying, to realize that I brought a little person into the world who is completely dependent on my husband and me for survival. Few would argue...

The Best Oncology Lesson

I was 2 months into my first-year fellowship at Georgetown Lombardi Comprehensive Cancer Center in Washington, DC, when I learned the best oncology lesson of my career. I owned a copy of DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology and had read Cancer Treatment...

American Society of Hematology Recognizes Laurence Boxer, MD, and Ralph Nachman, MD, for Outstanding Mentorship

The American Society of Hematology (ASH) will honor Laurence Boxer, MD, and Ralph Nachman, MD, with 2016 Mentor Awards at the 58th ASH Annual Meeting and Exposition in San Diego, California, for their sustained, outstanding commitment to the training and career development of early-career...

George Q. Daley, MD, PhD, Named Dean for Faculty of Medicine at Harvard Medical School

George Q. Daley, MD, PhD, a leader in stem cell science and cancer biology whose work spans the fields of basic science and clinical medicine, will become the next Dean of the Faculty of Medicine at Harvard Medical School. He will begin his duties on January 1, 2017. Dr. Daley is currently...

issues in oncology

Addressing the Significant Disparities and Barriers to Health Care Experienced by LGBT Cancer Survivors

In 2011, the Institute of Medicine (IOM) published its landmark report “The Health of Lesbian, Gay, Bisexual, and Transgender People: Building a Foundation for Better Understanding,” which recognized the scarcity of research in lesbian, gay, bisexual, and transgender (LGBT) individuals and the...

health-care policy

ASCO Applauds Bold Recommendations From Cancer Moonshot Blue Ribbon Panel

ASCO commended the Cancer Moonshot Initiative Blue Ribbon Panel for its ambitious recommendations to accelerate progress against cancer. “We applaud the Blue Ribbon Panel for its work and the National Cancer Institute's (NCI's) National Cancer Advisory Board for convening the panel,”...

bladder cancer
kidney cancer
prostate cancer

Multitude of Mentors Help Shape an Illustrious Career in Oncology

Sumanta K. Pal, MD, has had a longer career in oncology than many other colleagues his age. Perhaps the reason for that may center on his starting college at the age 13 and medical school at the age of 17. Today this internationally recognized leader in genitourinary cancers is Assistant Professor ...

skin cancer

Management of Merkel Cell Carcinoma

A recent report regarding pembrolizumab (Keytruda) for advanced Merkel cell carcinoma ushered in a more optimistic era in the treatment of this rare but often lethal skin cancer.1 The ASCO Post spoke with one of the field’s leaders, Paul Nghiem, MD, PhD—the first author of the study—about the...

Appointments and Awards at the 2016 MASCC/ISOO Annual Meeting

At the 2016 Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) International Symposium on Supportive Care in Cancer in Adelaide, Australia, a new President of the organization was announced, and numerous awards were given to outstanding...

Matti Aapro, MD, Awarded MASCC’s Distinguished Service Award

Matti Aapro, MD, has been selected as the recipient of the Multinational Association of Supportive Care in Cancer’s (MASCC) 2016 Distinguished Service Award. The Award recognizes meritorious achievement and outstanding contributions to the Society and its mission. Candidates are nominated by their ...

geriatric oncology

ASCO 2016: Geriatric Oncology Highlights

Clinical trials focused on older adults with cancer were featured prominently at the 2016 ASCO Annual Meeting. There was a plenary session in glioblastoma, a clinical symposium on immunotherapy, and multiple educational lectures highlighting the growing literature and unique challenges in the...

AACI Names Three New Members to Board of Directors

The Association of American Cancer Institutes (AACI) has announced the election of Karen E. Knudsen, PhD; ­Norman Sharpless, MD; and Eduardo ­Sotomayor, MD, to the AACI Board of Directors. The new Directors’ 3-year terms will start on October 23, 2016, during the AACI/ Cancer Center Administrators...

James Morgan, PhD, Named Scientific Director at St. Jude

St. Jude Children’s Research Hospital has named James Morgan, PhD, Scientific Director and Executive Vice President. Dr. Morgan held the Interim Scientific Director post since 2015 and was formerly Chair of the Department of Developmental Neurobiology. As Scientific Director, Dr. Morgan will...

hematologic malignancies
leukemia
lymphoma
multiple myeloma

Roundup of Selected Abstracts in Multiple Myeloma, Acute and Chronic Leukemia, and Advanced Lymphoma

In June 2016, the European Hematology Association Congress convened in Copenhagen, Denmark. The educational and scientific program highlighted state-of-the-art clinical practice and the latest findings in hematology research. The ASCO Post brings its readers brief summaries of some of the important ...

lymphoma

For High-Grade and Aggressive Non-Hodgkin Lymphomas, Treat Adults Like Children

Outcomes for adults with high-grade and aggressive non-Hodgkin lymphomas (NHLs) appear to be better when these patients are treated with pediatric-inspired protocols, according to Mitchell S. Cairo, MD, Chief of the Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Maria...

lymphoma

Early Relapse in Follicular Lymphoma: Clinical Trial Data May Guide Management Decisions

Approximately 20% of patients with follicular lymphoma will relapse within 2 years of diagnosis. Although the optimal management of these patients has not been established, clinicians may be guided by data from recent clinical trials, according to Nathan H. Fowler, MD, Associate Professor and...

prostate cancer

PSA-Based Computational Model Predicts Time to Relapse After Prostate Cancer Surgery

Approximately one in four patients who undergo radical prostatectomy experience a cancer recurrence. Now a study by Stura et al investigating a prostate-specific antigen (PSA)-based computational model that uses four consecutive postsurgical PSA values has found the mathematical model to be highly...

colorectal cancer

Retinoic Acid May Suppress Colorectal Cancer Development

Retinoic acid may play a critical role in suppressing colorectal cancer in mice and humans, according to researchers at the Stanford University School of Medicine. Mice with the cancer have lower-than-normal levels of the metabolite in their gut, the researchers found. Furthermore, colorectal...

health-care policy
issues in oncology

Researchers Question Process for Reviewing Coverage of 'Off-Label' Cancer Drug Use

A group of University of North Carolina (UNC) Lineberger Comprehensive Cancer Center researchers is calling for an overhaul of the process that determines which cancer drugs used off-label—or beyond their approved use—are reimbursed by federally funded health insurance in the United...

Cancer Research Institute to Honor Three Scientists for Outstanding Contributions to Cancer Immunotherapy Research

The Cancer Research Institute (CRI), a nonprofit organization established in 1953 to advance biomedical research with the goal of developing lifesaving immunotherapies for all forms of cancer, will bestow its highest honors on three scientists who have made fundamental contributions to the fields...

Former Clinical Director at the NCI, Gregory A. Curt, MD, Dies

In MemoriamGregory A. Curt, MD1952 – 2016 Gregory A. Curt, MD, Former Clinical Director at the National Cancer Institute (NCI) and nationally regarded expert on translational oncology died on July 31, 2016. He was 64 years old. Dr. Curt received his MD with distinction in research from the...

Four Young Scientists Receive Damon Runyon–Sohn Pediatric Cancer Research Fellowship Awards

The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon ­Runyon–Sohn Pediatric Cancer Research Fellowship Award, committing nearly $1 million to help address a critical shortage of funding for pediatric cancer research. The...

geriatric oncology

Spotlight on ASCO’s Geriatric Oncology Webpage

With the increasing population of older adults with cancer, there has been a commensurate need for more readily available and widely accessible educational and clinical resources in geriatric oncology. As part of the Cancer and Aging Research Group and ASCO’s Geriatric Oncology Special Interest...

issues in oncology
health-care policy

Six Perspectives on the Cancer Moonshot Goal of Making 10 Years of Progress in 5 Years

The Cancer Moonshot initiative is bringing together scientists, oncologists, patient advocates, and representatives of the biopharmaceutical industry with renewed collaborative focus and the ambitious objective of consolidating 10 years of cancer research in 5 years. Achieving this outcome will...

Indiana University School of Medicine Receives $2 Million Gift

The children of Indianapolis philanthropists Sidney and Lois ­Eskenazi have made a $2 million gift to the Indiana University School of Medicine to be used to recruit a highly accomplished researcher focused on discovering new ways to treat, diagnose, and prevent cancer. The gift, to honor their...

ASTRO Awards $275,000 in Grants to Support Early Career Researchers in Radiation Oncology

The American Society for Radiation Oncology (ASTRO) has selected four early career scientists to receive a total of $275,000 in research awards, including one winner of the ASTRO Junior Faculty Career Research Training Award and three recipients of ASTRO Resident/Fellows in Radiation Oncology...

lymphoma

Understanding Double-Hit Lymphomas and Optimizing Management

Double-hit lymphomas are a challenging subset of high-grade B-cell lymphomas, previously characterized histologically as diffuse large B-cell lymphoma or B-cell lymphoma unclassifiable with intermediate features between diffuse large B-cell lymphoma and Burkitt lymphoma. Expert guidance in their...

issues in oncology
supportive care

ASCO’s 2016 Quality Training Program: Meet the First International Participant From Greece

Launched in 2014, ASCO’s Quality Training Program was developed to prepare oncology providers to design, implement, and lead successful quality-improvement activities in their practices. It is a 6-month program that includes a structured and facilitated improvement project selected by each...

survivorship

Late Cardiac Effects of Cancer Treatment

The combination of more precise diagnostic tools and advances in surgery, chemotherapy, radiation therapy, and targeted therapy in the treatment of cancer has led to unprecedented numbers of cancer survivors in the United States—more than 15.5 million, according to the latest figures from the...

issues in oncology

Psychological Impact of Genetic Testing to Be Explored in Subset of NCI-MATCH Trial Patients

The ECOG-ACRIN Cancer Research Group has received federal approval to add a quality-of-life research study, COMmunication and Education in Tumor Profiling, or COMET (EAQ152), to the NCI-MATCH (EAY131) trial already underway. Using feedback surveys before and after a patient undergoes tumor gene...

Chinese Journal of Cancer Collecting 150 Most Important Questions in Cancer Research and Clinical Oncology

The Chinese Journal of Cancer (CJC) is soliciting the 150 most important questions in cancer research and clinical oncology from cancer researchers around the world. The editors of CJC believe this will help provide important insights and guidance in future efforts to advance cancer research...

Internationally Renowned Geneticist, Alfred George Knudson, MD, PhD, Dies

Considered a visionary in cancer research, Alfred George Knudson, MD, PhD, was internationally recognized for his “two-hit theory” of cancer causation, which explained the relationship between hereditary and nonhereditary cancer types, predicting the existence of tumor suppressor genes. Dr. Knudson ...

Pancreatic Cancer Action Network Appoints Four Leaders to Its Scientific and Medical Advisory Board

The Pancreatic Cancer Action Network has added four leaders from across the country to its Scientific and Medical Advisory Board.  “Members of the Pancreatic Cancer Action Network Scientific and Medical Advisory Board have committed their careers to change the course of a deadly and complex...

ASTRO Members Elect Five New Officers to Board of Directors

Members of the American Society for Radiation Oncology ­(ASTRO) have elected five new officers to the Society’s Board of Directors, including President-Elect, Secretary/Treasurer-Elect, and Vice-Chairs of three of ASTRO’s five councils (Clinical Affairs and Quality, Education, and Government...

A Ruby Anniversary

On July 16, 1975, at 26 years of age, after almost 6 months of observing a left epididymal mass slowly enlarge, with workup for epididymal tuberculosis, I finally underwent a left inguinal orchiectomy and resection of what proved to be a pure seminoma. A subsequent lymphangiogram was reported to...

The Building Block of Life, Brick by Brick

BookmarkTitle: The Gene: An Intimate HistoryAuthor: Siddhartha Mukherjee, MDPublisher: ScribnerPublication date: May 2016Price: $32.00; hardcover, 608 pagesOn February 28, 1953, James Watson and Francis Crick entered The Eagle, a favorite watering hole for researchers working at the University of...

lung cancer

David LeDuc Named Executive Director of Addario Lung Cancer Foundation

The Bonnie J. Addario Lung Cancer Foundation (ALCF) has announced that it has appointed David LeDuc as its new Executive Director. Mr. LeDuc most recently served as the Senior Director of Strategic Alliances for the Addario Lung Cancer Medical Institute (ALCMI), a partner foundation to ALCF, where ...

Measures of Success

I was raised to be an engineer. I grew up in an industrial community, worked summer jobs in a U.S. Steel chemical plant, and was good at science and math. My career choice was straightforward: I went to an engineering university. My first semester freshman year included a mandatory introduction...

Maryland Proton Treatment Center Appoints Charles B. Simone II, MD, New Medical Director

Charles B. Simone II, MD, has been named the new Medical Director of the Maryland Proton Treatment Center (MPTC). Dr. Simone will begin work in November 2016. As Medical Director, Dr. Simone will continue to define and implement processes ensuring that MPTC is integrated into the radiation...

Andrew Olshan, PhD, Elected President of the Society for Epidemiologic Research

Andrew Olshan, PhD, Associate Director of Population Sciences and Co-Leader of the Epidemiology Program at UNC Lineberger Comprehensive Cancer Center, has been elected President of the Society for Epidemiologic Research, the oldest and largest general epidemiology society in North America. He will ...

issues in oncology
global cancer care

Making a Difference in the Lives of Others

Quyen D. Chu, MD, MBA, FACS, this year’s recipient of ASCO’s Humanitarian Award, lives by the axiom that “One person can make a positive difference in the lives of others.” Although the term has become cliché, the experiences in Dr. Chu’s life and oncology career prove just how profound and...

Abhishek Aphale, MD, Joins Department of Dermatology at Fox Chase Cancer Center

Abhishek Aphale, MD, has been appointed Assistant Professor of Dermatology at Fox Chase Cancer Center. Dr. Aphale earned his medical degree from the Robert Wood Johnson Medical School of Rutgers University. He completed his residency training at the University of Michigan and a Procedural...

issues in oncology
geriatric oncology

Safety Concerns Weigh Heavily in Elderly Patients With Cancer

Active pharmacovigilance in detecting and assessing the safety signals related to drugs and devices, and disseminating those findings to relevant stakeholders, is an important component in delivering safe, high-quality care in the cancer setting. To reach a better understanding of this issue,...

Daniel F. Hayes, MD, FASCO, Leader in Translational Research, Begins Term as ASCO President

In 1995, Daniel F. Hayes, MD, FASCO, gathered with several other oncologists at a conference center in San Francisco to begin writing the first-ever ASCO guidelines on cancer treatment. He and his colleagues felt like pioneers scouting uncharted frontier. “I’ll never forget, that first hour or so, ...

supportive care
symptom management

More Focus Needed on Chemotherapy-Induced Nausea as a Cluster of Symptoms

Management of chemotherapy-induced vomiting has improved with the use of antiemetics, but chemotherapy-induced nausea remains a major clinical problem, according to Alex Molassiotis, RN, PhD, Professor and Head of the School of Nursing at The Hong Kong Polytechnic University. And, he added, the...

supportive care
symptom management

Dealing With GI Toxicities After Chemoradiation

Chemotherapy- and radiotherapy-induced gastrointestinal (GI) toxicities have risen alongside improved survival rates for many cancers, according to Jervoise Andreyev, MA, PhD, Consultant Gastroenterologist in GI Consequences of Cancer Treatment at the Royal Marsden Hospital in London. “For every...

breast cancer

African American Women More Likely to Choose Autologous Breast Reconstruction Over Implant-Based Reconstruction

African American women undergoing mastectomy for breast cancer are more likely than white women to undergo autologous breast reconstruction using their own tissue, rather than implant-based reconstruction, reported Sharma et al in Plastic and Reconstructive Surgery. “African American race...

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