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Marilyn J. Heine, MD, FACEP, FACP, FCPP, Elected AMA Council on Legislation Chair

During its June meeting, the American Medical Association (AMA) Council on Legislation chose Marilyn J. Heine, MD, FACEP, FACP, FCPP, as its new Chair. The Council reviews proposed federal legislation and recommends appropriate action in accordance with AMA policy. It also develops model state...

Blood Cancer Discoveries Program Names Grant Recipients

The Leukemia & Lymphoma Society, the Mark Foundation for Cancer Research, and the Paul G. Allen Frontiers Group recently announced the awarding of more than $6.75 million to nine scientists. Each project will be supported by an award of $750,000 over a 3-year period. Grant Recipients The Blood ...

NYU Langone Health’s Perlmutter Cancer Center Welcomes Janice M. Mehnert, MD, as Associate Director for Clinical Research

Janice M. Mehnert, MD, a researcher in early-phase therapeutics and the treatment of skin malignancies, has been appointed Associate Director for Clinical Research at New York University Langone Health’s Perlmutter Cancer Center. Dr. Mehnert was Associate Professor of Medicine at Robert Wood...

covid-19

AACR Holds COVID-19 and Cancer Virtual Meeting

The American Association for Cancer Research (AACR) hosted a virtual meeting on COVID-19 and cancer earlier this month (July 20–22, 2020). The virtual event, “COVID-19 and Cancer,” featured presentations from leaders in the fight against the pandemic, including three keynote lectures. In an opening ...

leukemia
geriatric oncology

Expert Point of View: Alice Mims, MD

Alice Mims, MD, Associate Professor of Hematology at The Ohio State University Comprehensive Cancer Center–The James, shared her insights on the VIALE-A study. “The results of the VIALE-A study have been highly anticipated and are exciting, given the improvement seen in both overall survival and...

issues in oncology

Deborah Schrag, MD, MPH, on Clinical Trial Design: Statistical Options and Challenges

Deborah Schrag, MD, MPH, of Dana-Farber Cancer Institute, offers her perspective on near-equivalence, Bayesian noninferiority, and the value of cancer drug optimization.

issues in oncology

Deborah Schrag, MD, MPH, on Clinical Trial Design: Statistical Options and Challenges

Deborah Schrag, MD, MPH, of Dana-Farber Cancer Institute, offers her perspective on near-equivalence, Bayesian noninferiority, and the value of cancer drug optimization.

geriatric oncology

The Importance of Measuring Health-Related Quality of Life in Older Adults

Compared with younger patients, older patients with cancer face unique challenges because many of them have age-related decreases in health-related quality of life. This can be a result of many factors, such as comorbidities, mental health, physical impairment, and financial stressors. A diagnosis...

Patricia S. Steeg, PhD, Receives Women in Cancer Research Charlotte Friend Lectureship

The American Association for Cancer Research (AACR) has honored Patricia S. Steeg, PhD, with its 2020 Women in Cancer Research Charlotte Friend Memorial Lectureship. Dr. Steeg, Co-Director of the Office of Translational Resources and Associate Director of the Center for Cancer Research at the...

Beth Levine, MD, Renowned Doctor and Researcher in the Field of Autophagy, Dies at 60

Beth Levine, MD, Professor of Internal Medicine and Microbiology, Director of the Center for Autophagy Research, and Charles Cameron Sprague Distinguished Chair in Biomedical Sciences at The University of Texas Southwestern Medical Center (UT Southwestern), and an investigator at the Howard Hughes ...

The Piano

The ASCO Post is pleased to reproduce installments of the Art of Oncology, as published previously in the Journal of Clinical Oncology. These articles focus on the experience of suffering from cancer or of caring for people diagnosed with cancer, and they include narratives, topical essays,...

A Doctor Battles a Deadly Disease and Turns Hope Into Action

From his early days, David Fajgenbaum, MD, was an overachiever in academics and sports, funneling his relentless drive and laser-like focus into everything he did. He dreamed of becoming a quarterback at a division I school, which he achieved, garnering a full scholarship to Georgetown University,...

genomics/genetics

Study Finds Young Adults With Cancer May Harbor Germline Mutations and Benefit From Germline Genetic Testing

According to the National Cancer Institute, each year, about 70,000 adolescents and young adults (AYAs)—those between the ages of 15 and39—are diagnosed with cancer.1 Evidence suggests that some cancers found in AYAs may have unique genetic and biologic features. The findings of a recent study by...

palliative care

A Palliative Care Specialist Explores What It Means to Live and Die With Dignity and Purpose

Palliative care’s road to acceptance as standard-of-care practice has been a remarkably unsmooth one, given its core mission: improving the quality of life of patients and their families by relieving the pain, symptoms, and stress of a serious or life-limiting illness. A person’s relationship with...

AACR Recognizes Achievements of Three Cancer Researchers

The American Association for Cancer Research (AACR) is honoring three clinical cancer researchers for their outstanding achievements. Jedd D. Wolchok, MD, PhD, FASCO, will receive the 2020 AACR–Joseph H. Burchenal Award for Outstanding Achievement in Clinical Cancer Research. Lisa A. Newman, MD,...

A Long-Time Student of Leadership, Brian J. Bolwell, MD, FACP, Ultimately Takes the Reins at the Taussig Cancer Institute

In this edition of the Living a Full Life series, guest editor Jame Abraham, MD, FACP, interviewed his colleague Brian J. Bolwell, MD, FACP, Chairman of the Cleveland Clinic Taussig Cancer Institute and Professor of Medicine at the Cleveland Clinic. Among other things, Dr. Bolwell discussed his...

Jessica Karen Wong, MD, MEng, Joins Radiation Oncology Department at Fox Chase

Fox Chase Cancer Center announced that Jessica Karen Wong, MD, MEng, recently joined the Department of Radiation Oncology as Assistant Professor in the academic clinician track. Dr. Wong completed her radiation oncology residency program at Fox Chase, where she served as Chief Resident in 2019 and...

geriatric oncology

Geriatric Assessment: What Are You Waiting For?

The ASCO20 Virtual Scientific Program was the forum for an unusual but profoundly important event in oncology. Four studies that should be practice-changing were presented.1-4 These studies provided irrefutable evidence that we can improve the quality of life of older patients by reducing toxicity. ...

lung cancer

Lung Cancer Research Foundation Names Trudy Oliver, PhD, to Its Scientific Advisory Board

The Lung Cancer Research Foundation (LCRF) recently announced that Trudy Oliver, PhD, has joined its Scientific Advisory Board. Dr. Oliver is Associate Professor of Oncological Sciences at the University of Utah’s Huntsman Cancer Institute (HCI), where she has served since 2011, and is an HCI...

Her Grandfather’s Medical Practice Inspired Nathalie LeVasseur, MD, BSc, FRCPC, to Improve the Lives of Women With Breast Cancer

At the 2018 ASCO Annual Meeting, Nathalie LeVasseur, MD, BSc, FRCPC, received the Annual Meeting Merit Award for a project titled, “Whole-Genome Sequencing in Metastatic Breast Cancer: Lessons Learned From the BC Cancer Personalized Oncogenomics Program.” Along with her clinical work, Dr....

ASCO Opens Search for Chief Medical Officer: Express Interest by August 21, 2020

ASCO is conducting an open search for the position of Chief Medical Officer and Executive Vice President, as current Chief Medical Officer, Richard L. Schilsky, MD, FACP, FSCT, FASCO, prepares to retire in February 2021. ASCO’s Chief Medical Officer applies his/her medical and scientific knowledge ...

Society for Immunotherapy of Cancer Names Recipients of Memorial Award and Lectureship

The Society for Immunotherapy of Cancer (SITC) has announced three recipients of the 2020 Richard V. Smalley, MD, Memorial Award and Lectureship, the society’s highest honor: they include Lieping Chen, MD, PhD, Gordon Freeman, PhD, and Arlene Sharpe, MD, PhD. The research conducted by Drs....

health-care policy

Addressing Discrimination and Bias in Medical Education

“As a medical student, I often felt marginalized from my medical community. I have been told that my name is ‘not American,’ fallen prey to being confused for support staff such as a janitor (even while wearing my white coat), and been asked questions like, ‘Where are you really from?’ or ‘How old...

breast cancer

No Survival Benefit from Local Therapy in de Novo Metastatic Breast Cancer Study

Results of the phase III E2108 study indicate that surgery and radiotherapy given after systemic treatment afforded no additional survival benefit among women with newly diagnosed metastatic breast cancer. The practice may, however, reduce locoregional progression of disease, according to a report...

leukemia

Courtney D. DiNardo, MD, on AML: Venetoclax and Azacitidine for Treatment-Naive Patients

Courtney D. DiNardo, MD, of The University of Texas MD Anderson Cancer Center, discusses data from her study of treatment-naive, predominantly older patients with acute myeloid leukemia who are ineligible for intensive therapy. The research shows venetoclax plus azacitidine improved response rates...

leukemia

Courtney D. DiNardo, MD, on AML: Venetoclax and Azacitidine for Treatment-Naive Patients

Courtney D. DiNardo, MD, of The University of Texas MD Anderson Cancer Center, discusses data from her study of treatment-naive, predominantly older patients with acute myeloid leukemia who are ineligible for intensive therapy. The research shows venetoclax plus azacitidine improved response rates...

genomics/genetics

Variant in Gene May Increase Cancer Risk in Those With Common TP53 R337H Mutations

Scientists studying a common TP53 R337H variant found among people of Brazilian descent discovered that a variant in the tumor-suppressor gene XAF1 increases cancer risk when combined with the inherited TP53 R337H mutation. These findings were published by Pinto et al in Science Advances. “We...

AMA Announces New President and President-Elect

Susan R. Bailey, MD, an allergist from Fort Worth, recently took office as the 175th President of the American Medical Association (AMA), the nation’s premier physician organization. Dr. Bailey is the third consecutive woman to hold the office, a record for the AMA. In addition, the organization...

An Honored Poet Explores a Lust for Life on the Boundaries of Near Death

"When the technician leaves the room, I turn my head toward the screen to interpret neoplasms, the webs of nerves, the small lit fonts in which my pathology and/or future or future end might be written. The first tumor I ever saw was a darkness on that screen, round with a long craggy finger...

Polio and Cancer Survivor Mickie McGraw Channels the Power of Creative Arts to Heal Broken Bodies and Minds

GUEST EDITOR Dr. Abraham is Professor of Medicine, Lerner College of Medicine, and Chair of the Hematology and Medical Oncology Department at Taussig Cancer Institute, Cleveland Clinic. In this edition of the Living a Full Life series, guest editor Jame Abraham, MD, FACP, spoke with pioneering art ...

breast cancer

You-Can-Do-Anything Philosophy Early in Life Inspired Breast Surgeon Laura S. Dominici, MD

Breast surgical oncologist Laura S. Dominici, MD, was born and reared in Litchfield, a small town in the southern portion of New Hampshire. “Our house was on a long dirt road, in a very rural area,” she shared. “There were only about 5,000 residents in the town. My mother was a teacher, and my dad...

Woman With an Ovarian Tumor

The text and photograph here are excerpted from a four-volume series of books titled Oncology: Tumors & Treatment, A Photographic History, The Anesthesia Era: 1845–1875 by Stanley B. Burns, MD, FACS, and Elizabeth A. Burns. The photograph appears courtesy of Stanley B. Burns, MD, and The Burns...

American Association for Cancer Research Announces Distinguished Public Service Award Recipients

The American Association for Cancer Research (AACR) recently announced the presentation of Distinguished Public Service Awards to four individuals whose work has exemplified the AACR’s mission to prevent and cure all cancers through research, education, communication, collaboration, science policy, ...

breast cancer

Improving Care for Women With Late-Stage Breast Cancer

The global toll of breast cancer on women is staggering. In 2018, nearly two million new breast cancer cases were diagnosed, an increase of more than 20% since 2008,1 and mortality rates have increased by 14%, bringing the annual number of deaths worldwide from the cancer to more than 611,625.2...

breast cancer

Study Finds No Survival Benefit From Local Therapy for de Novo Metastatic Breast Cancer

Women presenting with newly diagnosed de novo metastatic breast cancer derived no additional survival benefit from surgery and radiotherapy given after systemic treatment, although the practice may reduce locoregional progression of disease, according to the results of the phase III E2108 study...

issues in oncology

Lourdes Gil Deza on Caring for Transgender Patients With Cancer

Professor Lourdes Gil Deza, of the Instituto Oncológico Henry Moore, Buenos Aires, discusses her findings on the shortcomings of medical training when it comes to treating transgender patients, and the need to deepen clinical and communication skills to assist this population (Abstract 11002).

Roswell Park Names Leukemia Chief Eunice Wang, MD, Medical Director of Infusion Services

Roswell Park Comprehensive Cancer Center in Buffalo has named Eunice Wang, MD, Medical Director of Infusion Services for Roswell Park’s Chemotherapy and Infusion Centers.  Dr. Wang will oversee infusion services on the main campus and at Roswell Park’s satellite clinics, focused on a...

breast cancer

Talazoparib Yields No Overall Survival Benefit in EMBRACA Trial Update

The poly (ADP-ribose) polymerase inhibitor talazoparib did not improve overall survival in women with metastatic HER2-negative breast cancer and mutations in the BRCA1 and BRCA2 genes, according to new results from the phase III EMBRACA trial presented at the 2020 American Association for Cancer...

AACR Names Barbara J. Wold, PhD, Recipient of Distinguished Lectureship

The American Association for Cancer Research (AACR) announced the awarding of the 2020 AACR–Irving Weinstein Foundation Distinguished Lectureship to Barbara J. Wold, PhD. Dr. Wold was recently appointed as Director of the Merkin Institute for Translational Research at the California Institute of...

Tyler Jacks, PhD, Honored With 2020 AACR Princess Takamatsu Memorial Lectureship

The American Association for Cancer Research (AACR) has recognized Tyler Jacks, PhD, Fellow of the AACR Academy, with the 2020 AACR Princess Takamatsu Memorial Lectureship. Dr. Jacks is Director of the David H. Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology...

lymphoma

My Future Is Doled Out in Increments of 6 Months

In the fall of 2015, I was looking forward to a trip to Florida for a visit with my daughter and her family, along with a little relaxation. The evening before the trip, I experienced some abdominal pain that my wife, Angela, and I thought might be appendicitis. Concerned the problem could...

solid tumors
issues in oncology

Rates of Testicular Cancer Rising Among Racial/Ethnic Minorities in the United States

Between 2001 and 2016 in the United States, Asian/Pacific Islander men experienced the greatest increase in the incidence of testicular germ cell tumors, followed by Hispanic and American Indian/Alaska Native men, according to a study published by Ghazarian et al in Cancer Epidemiology, Biomarkers...

Phyllis F. Cantor Center for Research in Nursing and Patient Care Services Awarded $1.3 Million for Cancer Projects

Nurse-scientists from the Phyllis F. Cantor Center for Research in Nursing and Patient Care Services at Dana-Farber Cancer Institute, Boston, received more than $1.3 million in funding for two separate research projects. The American Association for Cancer Research announced that in partnership...

Pamela Hull, PhD, Appointed Associate Director of Population Science and Community Impact at Kentucky Cancer Center

The University of Kentucky Markey Cancer Center announced that medical sociologist Pamela Hull, PhD, will join the center as Associate Director of Population Science and Community Impact. She will also serve as the William Stamps Farish Endowed Chair in Cancer Research and join the University of...

Conquer Cancer Names 2020 Women Who Conquer Cancer Mentorship Award Recipients

Conquer Cancer, the ASCO Foundation®, has named Dawn L. Hershman, MD, MS, FASCO, as the 2020 Hologic, Inc Endowed Women Who Conquer Cancer Mentorship Award recipient, and Lillian L. Siu, MD, FRCPC, FASCO, as the International Women Who Conquer Cancer Mentorship Award recipient. The 2020 Women Who ...

issues in oncology

Results From an Oncology Hospital-at-Home Evaluation

Researchers at Huntsman Cancer Institute (HCI) at the University of Utah presented the first outcomes evaluation of an adult oncology hospital-at-home program during the ASCO20 Virtual Scientific Program (Abstract 7000). The study evaluated patients participating in HCI's Huntsman at Home program....

A Nobel Laureate’s Road to Research Is Not Without Challenges

The 2019 Nobel Prize for Physiology and Medicine was jointly awarded to three researchers. Their discoveries paved the way for promising new strategies to treat anemia, cancer, and many other diseases. One of the three Nobel Laureates is William G. Kaelin, Jr, MD, who continues his research at his...

International Medical and Radiation Oncologist Balances Cancer Research and Clinical Practice

The Revolutions of 1989 that resulted in the end of communist rule in Central and Eastern Europe and beyond began in Poland. Perhaps if not for that social upheaval, the career of internationally renowned oncologist Jacek Jassem, MD, PhD, would have taken a very different path. Dr. Jassem had fled...

A Lung Cancer Specialist’s Winding Journey From Venezuela to Wisconsin

Lung cancer specialist Narjust Duma, MD, was born and reared in Mérida, Venezuela, a city nestled on a plateau in the Venezuelan Andes. “I’m the daughter of two surgeons. After my parents divorced, I lived with my mother and spent a lot of time at the hospital where she worked. When she was in...

ASCO’s President Aims to Ensure Equitable Cancer Care for Every Patient

The desire to pursue a career in medicine took root when Lori J. Pierce, MD, FASTRO, FASCO, was a young child visiting family in segregated Ahoskie, North Carolina. She witnessed firsthand the impact the town’s lone African American family physician had on the community. When it came time to...

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