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issues in oncology

How The Max Foundation Is Accelerating Equitable Cancer Care Globally

When Pat Garcia-Gonzalez’ stepson, Max, was diagnosed with chronic myeloid leukemia (CML) in 1988 at the age of 14, the Internet was still in its infancy and decades away from the networking resource it has become today. Told that Max would need an allogeneic stem cell transplant to survive, the...

issues in oncology

Celebrating Advances in Cancer Care and a Look at How AI Is Revolutionizing Oncology

For the third year in a row, more than 250 leaders in cancer care, including cancer center directors, physicians, scientists, ethicists, journalists, public officials, and patient advocates, gathered at the Richard Nixon Presidential Library and Museum in Yorba Linda, California, to attend the...

genomics/genetics

Preventing Cancer Should Not Mean Sacrificing Quality of Life

My family first suspected we might have inherited the BRCA1/2 gene mutation after my father was diagnosed with his third cancer, colorectal cancer, following multiple bouts of squamous cell carcinoma and basal cell carcinoma beginning in his 30s and later prostate cancer. But the high risk of...

multiple myeloma

Understanding Risk Stratification in Monoclonal Gammopathy of Undetermined Significance

About 4 years ago, I [Jo Cavallo] wrote about the death of my brother Dom from multiple myeloma in 2011 and my subsequent enrollment in the PROMISE trial (ClinicalTrials.gov identifier NCT03689595). My goal for enrolling in the study was twofold: to honor Dom and others with the cancer and to make ...

palliative care

Understanding the Discordance About Prognosis Between Clinicians and Terminally Ill Patients and Their Surrogates

Research shows that about half of adults near the end of life in the United States are too ill to participate in decisions about whether to accept life-prolonging treatment,1 requiring family members and other proxies to serve as surrogate decision-makers for their critically ill loved ones....

issues in oncology

Are Major Adverse Financial Events Linked to a Later-Stage Cancer Diagnosis?

Studies have shown that millions of people in the United States are financially vulnerable because of low income, limited savings, or high levels of debt. In 2021, 32% of U.S. adults reported being unable to cover an unexpected expense of $400. A recent study by researchers at the American Cancer...

global cancer care

How ASCO’s Regional Councils Are Having an International Impact on Patients With Cancer

In September 2023, ASCO announced the establishment of its fourth regional council, the Central and Eastern European Regional Council, which includes representatives from 17 countries, with the goal of expanding ASCO’s mission globally to “conquer cancer through research, education, and promotion...

skin cancer

FDG PET/CT Imaging Performed After 1 Week of Immunotherapy May Predict Treatment Response in Patients With Advanced Melanoma

A prospective pilot study investigating the use of early fluorodeoxyglucose F-18 (FDG) positron-emission tomography/computed tomography (PET/CT) in patients with advanced melanoma has found that metabolic changes in melanoma metastases detected on early FDG PET/CT imaging are potentially predictive ...

breast cancer

My Breast Cancer Experience Has Led Me to Leverage My Expertise in Human-Centered Design to Transform Patient Care

The road to my breast cancer diagnosis in 2018 was long and tortuous. For 3 years leading up to the diagnosis, I had imaging scans and tissue biopsies every 3 months because of suspicious masses in my breasts. The uncertainty was so destabilizing that I was in a constant state of emotional unrest....

issues in oncology

Tackling the Challenges of Oncology Workforce Shortages, Increased Patient Demand, and Rising Costs of Care

In May 2023, The ASCO Post launched a new feature, View From the Top: The Future of Cancer Care Delivery, which explores how leaders in oncology are developing strategies to ensure continued innovative oncology care in an ever-changing health-care environment. In this installment, Guest Editor Jame ...

issues in oncology

American Cancer Society Annual Report Shows Cancer Mortality Still Declining, but Cancer Incidence Is Projected to Top 2 Million

Although overall cancer mortality has continued to decline, resulting in over 4 million fewer deaths in the United States since 1991, increasing incidence for 6 of the top 10 cancers pushed the projected number of new diagnoses to over 2 million (2,001,140) for the first time, according to the...

breast cancer
supportive care

Young Women With Breast Cancer: Discussing vs Pursuing Fertility Preservation

In 2023, nearly 300,000 new cases of invasive breast cancer were diagnosed in the United States, and approximately 56,000 new cases of ductal carcinoma in situ were diagnosed. Although most of those cancers are diagnosed in older adults, about 9% of all new cases of breast cancer are found in women ...

2023 Members Appointed to the National Cancer Advisory Board

In addition to Dr. Richard J. Boxer, the following names have been newly appointed to serve a 5-year term on the National Cancer Institute’s National Cancer Advisory Board: Margaret Anne Anderson, Managing Director of Deloitte Consulting LLP, Arlington, Virginia Ysabel Duron, Founder and Executive ...

issues in oncology

How Being a Member of the President’s National Cancer Advisory Board Is Contributing to High-Quality Oncology Care

This past year, President Joe Biden announced the appointment of six members to the National Cancer Advisory Board (NCAB; see related article). This board plays a crucial role in advising and assisting the director of the National Cancer Institute (NCI) in setting the activities of the national...

colorectal cancer
immunotherapy

Can Immunotherapy Induce Sustained Disease Control Among Patients With Colorectal Cancer?

Excluding skin cancers, colorectal cancer is the third most common cancer diagnosed in both men and women in the United States, and the third-leading cause of cancer-related deaths. According to the American Cancer Society, in 2023, it is estimated that about 52,550 individuals died from the...

issues in oncology
global cancer care

Improving Cancer Control in a Changing World

On October 16 and 17, 2023, the Union for International Cancer Control (UICC) welcomed more than 350 attendees from over 75 countries to its World Cancer Leaders’ Summit in Long Beach, California, to discuss some of the most challenging issues facing patients with cancer worldwide. The theme of...

multiple myeloma

I Don’t Want Cancer to Define Me

Except for a series of unexplained multiple broken bones and inexplicable excruciating pain in my right hip and leg, I had no other hallmarks of multiple myeloma when I was diagnosed with the disease at age 48 in 2014. My blood test values were all normal, and I didn’t have anemia or kidney damage. ...

lung cancer

American Cancer Society Releases Updated Lung Cancer Screening Guideline

Lung cancer incidence overall has been declining in the United States since 1992—and since 2006–2007 for both men and women by 2.7% annually and 1.1%, respectively—and overall mortality rates have declined in both men and women because of smoking cessation efforts and advances in therapy and early...

sarcoma

A Cancer Diagnosis at 19 Taught Me That It Takes Constant Vigilance to Stay Mentally Healthy

A lot of my experience with cancer is hazy to me. I was taking narcotics for pain around the clock when I was diagnosed with Ewing’s sarcoma in 2013, so there are some missing memories during those early days. I was 19 and a freshman in college when my symptoms started. I have always been active in ...

kidney cancer

Adjuvant Everolimus Improves Recurrence-Free Survival in Very High–Risk Renal Cell Carcinoma

A secondary analysis from the phase III SWOG S0931 EVEREST trial found that adjuvant everolimus given to patients with clear cell renal cell carcinoma at very high risk of recurrence after nephrectomy produced a statistically significant improvement in recurrence-free survival compared with placebo ...

colorectal cancer

Prevalence of Unsatisfactory Samples From FIT Tests for Colorectal Cancer Screening

A retrospective cohort study by Liu et al published in Cancer Epidemiology, Biomarkers & Prevention investigated the prevalence and reasons for an unsatisfactory fecal immunochemical test (FIT). Researchers found that over 10% of the tests used for routine colorectal cancer screening contained...

issues in oncology

AACR Annual Cancer Progress Report Highlights Scientific Advances Against Cancer, Challenges and Opportunities Ahead

The remarkable progress in medical research—primarily supported by federal investments in the National Institutes of Health (NIH) and the National Cancer Institute (NCI)—over the past 3 decades, coupled with advances in prevention and early detection, has led to a 33% reduction in cancer...

issues in oncology

How ASCO Is Tackling the Need to Improve Workforce Diversity and the Looming Oncology Workforce Shortage

On June 29, 2023, the U.S. Supreme Court, in a 6-to-3 decision, essentially overturned affirmative action in college admissions, which had allowed, since 1978, for colleges and universities to consider race as a factor in student admissions.1 The ruling will impact enrollment decisions at public...

issues in oncology

ASCO Launches ‘ASCO Certified’ to Ensure the Delivery of High-Quality, Patient-Centered Cancer Care to Every Patient

On October 25, 2023, ASCO announced the launch of its new flagship quality program ASCO Certified™, with the goal of ensuring that every patient with cancer has access to high-quality, patient-centered, coordinated cancer care.1 The program, which officially launched on October 27, 2023, to...

colorectal cancer

Having Colorectal Cancer at 32 Changed the Trajectory of My Life

I’ve been contending with health issues since I was 12, when I was diagnosed with Crohn’s disease. As I began my early 30s, I was feeling the healthiest of my life. I was working out 5 days a week and attributed sudden weight loss and fatigue to weight training and high-intensity Zumba classes....

issues in oncology

Patient-Facing AI in Cancer Care

Currently most use of artificial intelligence (AI) in cancer care has been limited to diagnostics, with the U.S. Food and Drug Administration approving nearly 700 medical devices that utilize AI and/or machine learning, the majority of which are used in the fields of radiology and pathology....

lung cancer

ACS Releases Updated Lung Cancer Screening Guideline

Lung cancer incidence overall has been declining in the United States since 1992 and since 2006–2007 for both men and women by 2.7% annually and 1.1%, respectively, and overall mortality rates have declined in both men and women due to smoking cessation efforts and advances in therapy and early...

ASCO Launches ‘ASCO Certified’ to Ensure the Delivery of High-Quality, Patient-Centered Cancer Care to Every Patient

On October 25, 2023, ASCO announced the launch of its new flagship quality program ASCO Certified™, with the goal of ensuring that every patient with cancer has access to high-quality, patient-centered, coordinated cancer care.1 The program, which officially launched on October 27, 2023, to...

issues in oncology

Overcoming the Challenges of Treating Adolescents and Young Adults With Cancer Living in Rural Communities

It is widely acknowledged that patients with cancer living in rural areas of the United States face limited access to medical and oncology providers, often have to travel long distances to receive care, and experience obstacles in clinical trial participation—all of which affect quality of care and ...

covid-19

Annual Report to the Nation on COVID-19’s Impact on Cancer Diagnosis Finds Sharp Declines in New Diagnoses of Six Major Cancers

Findings from the Annual Report to theNation on the Status of Cancer, Part 2: Early Assessment of the COVID-19 Pandemic’s Impact on Cancer Diagnosis show new diagnoses of six major cancer types in the United States fell sharply between March and May 2020, coinciding with the beginning of the...

leukemia

Getting a Cancer Diagnosis at Age 16 Has Taught Me to Live in the Present

I have been fascinated with death since I was 3 years old. I remember going to my great-grandfather’s funeral and asking my mother where my great-grandfather was. She said he is in heaven. I asked her if I were going to heaven, too, and she said, “Yes, but not for a long time.” Today, I don’t...

issues in oncology

Adults Living Alone Are at Higher Risk of Cancer Mortality Compared to Adults Living With Others

Adults living alone had a 32% higher risk of cancer death than those living with others, according to study results from researchers at the American Cancer Society. For men, the risk was even greater—38%—compared to a 30% higher risk for women. The association between living alone and cancer...

kidney cancer

EVEREST Trial: Adjuvant Everolimus for High-Risk Clear Cell Renal Cell Carcinoma

A secondary analysis from the phase III SWOG S0931 EVEREST trial found patients with clear cell renal cell carcinoma at very high risk of recurrence after nephrectomy who received adjuvant everolimus had a statistically significant improvement in recurrence-free survival compared to patients who...

issues in oncology
survivorship

Many Survivors of Childhood Cancer Experience Lifelong Chronic Health Problems and Shorter Lifespans Than Their Healthier Peers

Each year, nearly 16,000 children between the ages of 0 and 19 years are diagnosed with cancer, and more than 85% survive for at least 5 years. Overall, this is a large increase in survivors since the mid-1970s, when the 5-year survival rate was just 58%. Today, approximately 500,000 people in the...

palliative care

ASCO Launches New Webinar: Making Palliative Care a Part of Your Oncology Practice

ASCO President Lynn Schuchter, MD, FASCO, has made access to palliative and supportive care among patients with cancer a central focus of her presidential term. Although not all cancer clinicians can be palliative care specialists, because palliative and supportive care are so essential to every...

kidney cancer
immunotherapy

Can AI Help Identify Kidney Tumors That May Respond to Immunotherapy?

Clear cell renal cell carcinoma is the most common type of kidney cancer, comprising 80% of all malignant tumors found within the kidney. Although some clear cell renal cell carcinoma tumors are sensitive to immune checkpoint inhibitors, currently, there are no measures to predict whether a tumor...

multiple myeloma

IVIG May Reduce Infection Risk Among Patients With Multiple Myeloma Receiving Anti-BCMA Therapy

Although the 5-year survival rate for multiple myeloma has increased over the past 2 decades—from about 35% in 2000 to approximately 62% in 2015—due to more effective therapies, the cancer remains incurable. According to the American Cancer Society, this year, nearly 36,000 individuals will be...

breast cancer

Tracking the Progress Being Made in the Treatment of Breast Cancer and the Challenges Ahead

Jame Abraham, MD, FACP, has been in the field of oncology for more than 2 decades, he and says this is both one of the most exhilarating and challenging times in cancer care. “What excites me the most are the innovations in treatment that are literally transforming the lives of our patients and...

multiple myeloma

Dendritic Cell Vaccine Plus Stem Cell Transplant for Multiple Myeloma

Although the development of new therapies for multiple myeloma has significantly improved response rates and outcomes for patients with the blood cancer, most patients eventually relapse, including those who initially achieved remission. A phase I study is investigating whether a dendritic cell...

sarcoma

A Diagnosis of Ewing Sarcoma Altered the Trajectory of My Life

In August 2014, just a few weeks after my 15th birthday, my body began sending me a lot of worrisome signals that life as I knew it would soon be over. The year before, I had developed a hematoma in my right femur, which was resolved with surgery. But now the pain I was experiencing in that leg was ...

issues in oncology

Structural Racism’s Effect on Cancer Mortality Rates

Racial minority patients are impacted differently by the social and physical characteristics of their environments, which may negatively affect cancer outcomes compared with White patients with cancer, according to a new study by Robinson-Oghogho et al presented during the 16th AACR Conference on...

colorectal cancer

Does Colon Tumor Location Play a Role in Metastasis and Survival?

There have been demonstrated differences in tumor cell metabolism between right-sided and left-sided colorectal tumors, which could explain the differences observed in their clinical behavior, especially in metastatic disease. Now, new research has found that patients with right-sided colorectal...

issues in oncology
covid-19

Annual Report to the Nation on the Status of Cancer, Part 2, Focuses on COVID-19’s Impact on Cancer Diagnoses

The Annual Report to the Nation on the Status of Cancer, Part 2—published by Negoita et al in the journal Cancer—showed that new diagnoses of six major cancer types in the United States fell sharply between March and May of 2020, coinciding with the beginning of the COVID-19 pandemic. The six...

lymphoma

Finding a New Life Purpose After Cancer

In the summer of 2012, I was living my dream. At 28 years old, I had gone from an impoverished childhood in South Central Los Angeles to the high life in the city of Los Angeles. Unable to afford to go to college, an after-school program helped launch me into a career in the hospitality industry. I ...

issues in oncology

Accelerating Progress Against Cancer and Other Life-Threatening Diseases

Cancer—and the quest to accelerate more effective treatments and potential cures for all life-threatening diseases—has perhaps shaped the life of financier Michael Milken more than his legendary career on Wall Street. In the early 1970s, Mr. Milken’s mother-in-law was diagnosed with metastatic...

colorectal cancer

Colorectal Cancer Screening: Major Communication Gap in the Clinical Setting

According to the American Cancer Society, colorectal cancer is the second-leading cause of cancer-related death in the United States. In 2023, the disease is expected to cause an estimated 52,550 deaths. Studies show that receiving a clinician recommendation is the strongest and most consistent...

legislation
issues in oncology

Cancer Moonshot Initiative Receives $240 Million Boost

On September 13, during a meeting of the Cancer Cabinet, President Joe Biden and First Lady Dr. Jill Biden announced a $240 million investment to accelerate advances in cancer-related projects, with the aim of improving treatments and reducing cancer mortality over the next 25 years. The funding,...

issues in oncology
health-care policy
legislation

AACR Issues Annual Cancer Progress Report

The remarkable progress in medical research—primarily supported by federal investments in the National Institutes of Health (NIH) and the National Cancer Institute (NCI)—over the past 3 decades, coupled with advances in cancer prevention and early detection, has led to a 33% reduction in cancer...

lung cancer

Data Analysis of Young-Onset Lung Cancer Reveals Key Differences Compared With the Disease in Older Adults

Lung cancer, both small cell and non–small cell, is the second most common cancer in both men and women in the United States, with about 238,340 new cases diagnosed each year, and the leading cause of cancer-related mortality, accounting for more than 127,000 deaths annually.1 Lung cancer in...

lymphoma
pancreatic cancer

Instinct and Perseverance Helped Save Me From Two Cancers

My intuition about my health has served me well over the past 10 years, possibly even saving my life from two serious cancers. In 2013, I was diagnosed with follicular lymphoma. I believe that my awareness of changes in my body led to its early discovery. One evening, after exercising at the gym...

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