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Your search for Jo Cavallo matches 1463 pages

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head and neck cancer

A Laryngectomy Altered How I See Myself in the World

There is a 2-decades-long separation between the time I was diagnosed with oropharyngeal squamous cell carcinoma in 1996 and my laryngectomy in 2016. The surgery was necessary because of the long-term damage to my larynx from the radiation therapy I received. In 1996, I had a low-grade sore throat...

issues in oncology

How ASCO Is Helping Members Navigate the Cancer Care Terrain for Pregnant Patients Since the Reversal of Roe v Wade

In response to the U.S. Supreme Court decision in Dobbs v Jackson Women’s Health Organization overturning Roe v Wade, eliminating the constitutional right to an abortion and returning the power to regulate reproductive health for women to the states, ASCO, the American Cancer Society Action...

lung cancer

I’ve Had Two Primary Lung Cancers, and They Haven’t Defeated Me

I don’t know why I am so susceptible to developing lung cancer. Since 2014, I have been diagnosed with both non–small cell lung cancer (NSCLC) and small cell lung cancer, each occurring in my right lung. I have also been diagnosed with precancerous colon polyps, which necessitated invasive surgery. ...

breast cancer

Study Finds Nearly Half of Black Women With Metastatic Breast Cancer Never Receive Information About Clinical Trial Participation

When Stephanie L. Walker, RN, was diagnosed with metastatic breast cancer in 2015, she was not given information about an appropriate clinical trial or help navigating her way through the financial difficulties she was having after a stroke from complications of the cancer forced her to leave her...

issues in oncology

How to Advance Antiracist Approaches to Patient Engagement in AYA Oncology and Research

Among the topics discussed at the 4th Global Adolescent and Young Adult Cancer Congress held online in December 2021 was the urgent need for clinicians, researchers, and advocates in adolescent and young adult (AYA) oncology to join forces to eradicate racist approaches to patient engagement in...

prostate cancer

Providing a Tailored Approach to Prostate Cancer Care for Gay and Bisexual Men

It is estimated that one in eight men will be diagnosed with prostate cancer in his lifetime. The disease is so prevalent, and other than skin cancer, it is the most common cancer diagnosed in American men. According to the American Cancer Society, this year, about 268,490 new cases of prostate...

breast cancer

Why Are Young Adult Women Developing Later-Stage, More Aggressive Breast Cancer Than Older Women?

It has been well documented that breast cancer is the most common malignancy in adolescent and young adult (AYA) women aged 15 to 39 years, accounting for 30% of cancers among this population.1 In addition, 5.6% of all invasive breast cancers occur in AYA women.1 A presentation by Rebecca H....

hematologic malignancies
immunotherapy
symptom management

Incidence of Neurologic Side Effects From CAR-T Cell Therapy Is Higher in Patients With Hypophosphatemia, Study Finds

Patients with B-cell malignancies who had hypophosphatemia experienced a higher incidence and severity of neurologic side effects from chimeric antigen receptor (CAR) T-cell therapy, according to a study by Nowicki et al published in Cancer Immunology Research. The study results imply that...

issues in oncology
breast cancer
gynecologic cancers
colorectal cancer

Use of Remote Interventions Increased Adherence to Cancer Screenings Among Women in Rural Areas

Studies show that rural populations experience greater cancer disparities across the cancer control continuum—from prevention and incidence to survivorship and mortality—compared with their urban counterparts. Those living in rural parts of the United States also tend to have lower cancer screening ...

issues in oncology
global cancer care

Maternal Deaths From Cancer Worldwide Have Led to Approximately 1 Million New Maternal Orphans

In 2020, 4.4 million women died from cancer worldwide, leaving behind an estimated 1.04 million maternal orphans (defined as children aged 18 years and younger who have lost their mother), according to the results from a study by Guida et al presented during a press conference at the Union for...

breast cancer
palliative care
survivorship

ASCO Launches Webinar Series to Close the Global Divide Between Survivorship and Palliative Care in Breast Cancer

In honor of Breast Cancer Awareness Month and World Hospice & Palliative Care Day, ASCO and its partners—the International Association for Hospice & Palliative Care; Tómatelo a Pecho, A.C.; the University of Miami Sylvester Comprehensive Cancer Center and Institute for Advanced Study of the ...

breast cancer

Living With Metastatic Breast Cancer

After my first breast cancer diagnosis, in 2010, the odds for a cure were seemingly all weighted in my favor. A routine mammogram screening had picked up a small—less than 1 cm—mass in my right breast, and a tissue biopsy confirmed it was stage I estrogen receptor–positive breast cancer. I had no...

global cancer care

Update on the Impact of the Russian Invasion of Ukraine on Patients With Cancer

In the more than 7 months since Russia invaded Ukraine on February 24, 2022, cancer care for Ukrainian citizens has changed dramatically. Ukraine was once a country able to provide its approximately 160,000 newly diagnosed patients with cancer each year with modern diagnostic methods, including...

issues in oncology

AACR Cancer Progress Report 2022 Shows Cancer Mortality Rates Continue to Decline, but Challenges Remain

Advances in more effective treatment and early detection diagnostics, coupled with reductions in smoking rates, have resulted in a 32% decline in cancer mortality in the United States since 1991, translating into nearly 3.5 million lives saved, according to the newly released American Association...

hepatobiliary cancer

Individuals of Mexican Descent May Have Higher Risk of Liver Cancer With Each Successive Generation

Studies show that Hispanic individuals have higher incidence rates of developing liver cancer and higher mortality rates—by 50% or more—than non-Hispanic White individuals for several cancers, including liver cancer. A new study investigating hepatocellular carcinoma among successive generations of ...

issues in oncology

Do LGBTQI+ Patients With Cancer Receive Mental Health Information Tailored to Their Needs?

Although customized health education materials for lesbian, gay, bisexual, transgender, queer, and intersex (LGBTQI+) cancer survivors may play a pivotal role in their experiences throughout their cancer care continuum, a study by Burnett et al has found that regardless of their satisfaction with...

lymphoma

An Aggressive Type of Non-Hodgkin Lymphoma Threatened My Life

I was just 31 and about to give birth to my fourth child, Yitzchok, when I received a diagnosis of primary mediastinal large B-cell lymphoma. The news was terrifying and crippling. For months, I had been experiencing shortness of breath, coughing, and a pain in my left shoulder, all of which were...

issues in oncology

How EQRx Aims to Reengineer the Health-Care System to Produce More Effective, Less Costly Cancer Drugs

The numbers are dizzying. The costs of cancer care in the United States are rising so fast that by 2030, it is projected the national cancer-attributable costs will total more than $246 billion, up from $183 billion in 2015—a 34% increase.1 And although the total global economic burden of cancer is ...

multiple myeloma
immunotherapy

Durability of Responses to BCMA CAR T-Cell Therapy in Patients With Multiple Myeloma May Depend on Specific Components of the Tumor Microenvironment

Currently, there are two U.S. Food and Drug Administration–approved chimeric antigen receptor (CAR) T-cell therapies targeting the B-cell maturation antigen (BCMA) for adult patients with relapsed or refractory multiple myeloma: idecabtagene vicleucel and citacabtagene autoleucel. However, although ...

prostate cancer

Surviving Advanced Prostate Cancer Has Made Me a More Empathetic Physician

My diagnosis of terminal prostate cancer 3 years ago was filled with irony. As an interventional radiologist, I have treated hundreds of patients with advanced prostate cancer, and I knew my prognosis wasn’t good. After experiencing some of the common symptoms of the cancer, including voiding...

multiple myeloma

Is Science Getting Closer to Preventing Multiple Myeloma?

About 3 years ago, researchers from Dana-Farber Cancer Institute launched PROMISE (Predicting Progression of Developing Myeloma in a High-Risk Screen Population; ClinicalTrials.gov identifier NCT03689595), a large, ambitious screening study to identify individuals at high risk of developing...

palliative care

Is Advance Care Planning of Any Value?

An article in The New York Times earlier this year crystallized the dilemma facing health-care providers when they are presented with a patient in a life-threatening situation: Should they rely on advance care directives written years prior to the current medical situation to accurately determine...

solid tumors

Thriving After a Diagnosis of Stage II Anal Cancer

About 7 years ago, I had emergency hernia surgery and soon after began experiencing severe constipation and abdominal bloating. I had started to have minor symptoms leading up to the surgery, but now the pain and exhaustion of trying to have a bowel movement became unbearable. I met with a...

issues in oncology

ASCO-ACCC Recommendations to Reduce Barriers to Clinical Trial Enrollment

Here is a summary of the strategies developed by ASCO and the Association of Community Cancer Centers (ACCC) to increase participation by minority patients in cancer clinical trials and ensure greater equity, diversity, and inclusion in research studies. For a detailed list of the recommendations,...

issues in oncology

How ASCO and ACCC Aim to Increase Diversity in Clinical Trials and Close the Equity Gap in Cancer Care

Research shows that although 15% of Black individuals and 13% of Hispanic individuals have cancer in the United States, only between 4% and 6% of clinical trial participants are Black and between 3% and 6% are Hispanic.1-3 To improve these statistics, in 2020, ASCO and the Association of Community...

lung cancer

How Smoking Cessation After a Lung Cancer Diagnosis Improves Overall Survival

Despite data showing that cigarette smoking is the number one risk factor for the development of lung cancer,1 and a leading cause of preventable disease, disability, and death in the United States, an estimated 30.8 million American adults continue to smoke cigarettes.2 Globally, the number of...

breast cancer
immunotherapy

Patients With Triple-Negative Breast Cancer Benefited From Presurgical Immunotherapy, Regardless of Race

Black women are twice as likely to be diagnosed with triple-negative breast cancer compared with White women, 28% more likely to die from the disease than White women, and are less likely to be treated with surgery and chemotherapy, according to a study published in 2021. Despite these statistics,...

breast cancer

Use of Menopausal Hormone Therapy and Breast Cancer Mortality

Although aromatase inhibitors are effective in reducing estrogen levels and the risk of cancer recurrence in women diagnosed with hormone receptor–positive breast cancer, they can also cause myriad side effects, including genitourinary problems associated with menopause such as vaginal dryness,...

Former NCI Director Takes Stock of His Accomplishments and Looks Ahead to the Next Challenge

After nearly 5 years as Director of the National Cancer Institute (NCI), interrupted by 7 months as Acting Commissioner for the U.S. Food and Drug Administration (FDA), Norman E. “Ned” Sharpless, MD, left his position on April 29 to concentrate on his family and contemplate his next career choice....

multiple myeloma
immunotherapy

CAR T-Cell Therapy Gave Me Back a High-Quality Life

A radiologist by training, I knew the minute I saw the results from my chest x-ray that I had multiple myeloma. In 2015, I was semiretired and had just taken up the game of golf. After making a big swing at the ball, I instantly felt pain in my ribs and thought I had either pulled an intercostal...

colorectal cancer

Analysis Finds Prevalence of Colorectal Cancer Screenings Remains Low in Younger Adults

In 2020, nearly 150,000 Americans, mostly those aged 50 and older, were diagnosed with colorectal cancer. However, about 18,000 of those individuals were younger than age 50. And while colorectal cancer rates have decreased for people over age 50, they have been increasing by 51% since 1994 for...

lung cancer
immunotherapy

Immunotherapy Has Given Me Back My Life

Hearing the words “You have cancer” is a devastating blow, especially when the biggest health issues you’ve had to contend with over more than 6 decades are common colds and knee and hip replacements. But in 2017, the symptoms I thought were from a lingering summer cold drove me to seek medical...

breast cancer

Study Finds Diagnostic Mammography Performance Varies Across Racial and Ethnic Groups

The disparities in female breast cancer incidence and mortality among racial and ethnic groups is well documented. Studies show that while Black women have a lower incidence of breast cancer compared with White women, they are 41% more likely to die from the disease than White women. Breast cancer...

issues in oncology

How Social Media Is Fueling an Epidemic of Misinformation and Disinformation—and Distrust in Science

The COVID-19 pandemic and the confluence of events that followed—including the rapid development of vaccines, the mixed messaging on mitigation efforts to prevent coronavirus infection, and the growing political polarization—helped spark public mistrust and skepticism toward science. This mistrust...

issues in oncology

AACR Report Finds Racial and Ethnic Minorities Continue to Shoulder a Disproportionate Burden of Cancer

Although overall cancer incidence and mortality are declining across all population groups, compared with White individuals, racial and ethnic minorities and other medically underserved populations continue to shoulder a disproportionate burden of cancer, according to the study results published in ...

ASCO’s President-Elect Makes Partnering With Patients the Cornerstone of His Presidential Term

This year, Eric P. Winer, MD, FASCO, takes on two new leadership roles in his illustrious medical career. In February, Dr. Winer left his positions as Chief Clinical Development Officer and Senior Vice President for Medical Affairs at Dana-Farber Cancer Institute, and Leader of the...

issues in oncology
solid tumors

Race/Ethnicity and Poverty Are Associated With Worse Outcomes Among Children With High-Risk Neuroblastoma

Prior studies by the Children’s Oncology Group (COG) have demonstrated population-based disparities in late relapse rates among Black children with high-risk neuroblastoma, and trial-based disparities in relapse and survival among children living in poverty receiving postconsolidation...

health-care policy

Study Finds State Public Welfare Spending Was Associated With Improved 5-Year Overall Survival in Black Patients With Cancer

According to a recent report by The Commmonwealth Fund, “large racial and ethnic health inequities, driven by factors both inside and outside the health-care delivery system [in the United States], are common.” The result, according to the report, is that actions that could mitigate health...

lymphoma

Finding a New Normal After Classical Hodgkin Lymphoma

As every patient diagnosed with cancer knows, the disease affects not just your physical well-being, but your emotional well-being, too. I was just 35 years old when I was diagnosed with early-stage classical Hodgkin lymphoma this past summer, and the news came at a time when I was feeling in top...

palliative care

Understanding Oncologists’ Perceptions About Palliative Care and the Barriers Preventing Its Use

Despite studies showing the benefits of early palliative care in improving the quality of life of patients with advanced cancer (including reducing symptoms of depression),1 a recent survey of oncologists found there is broad variation in the appropriate utilization of this care.2 Conducted by...

issues in oncology

ASCO Sets Goals to Advance the Clinician-Educator Career Pathway in Oncology

Although most oncology program directors and associate or assistant program directors consider themselves clinician-educators, they receive little to no formal medical education training to nurture trainees into clinician-educator careers and do not have a clinician-educator track for their...

issues in oncology

The Impact of War on Patients With Cancer

Just days after Russia invaded Ukraine on February 24, ASCO, together with its partners the American Cancer Society (ACS) and the Sidney Kimmel Cancer Center–Jefferson Health, began assembling resources to establish a network of oncology professionals to help Ukrainian patients with cancer find...

global cancer care

Tackling the Global Burden of Cancer on Adolescents and Young Adults With Cancer

      Several recent studies examining the global burden of cancer on adolescents and young adults (AYAs) show the growing magnitude of the disease’s impact on the lives of individuals between the ages of 15 and 39. Although considered a rare occurrence, cancer in this age group has risen by...

global cancer care

How St. Jude and the WHO Are Sparking an International Movement to Increase Treatment Access for Children With Cancer

The toll of cancer on children, especially those living in low-resource countries, is staggering. Each year, an estimated 400,000 children and adolescents worldwide develop cancer,1 and despite improved survival rates, the global 5-year net childhood cancer survival rate is only 37.4%,2 making...

leukemia
survivorship

AYA Leukemia Survivors Have Higher Mortality Rates Than the General Population

Although considered a rare occurrence in adolescents and young adults (AYAs), aged 15 to 39 years, the incidence of cancer in this age group has been increasing by approximately 30% since the 1970s. This year, it is estimated that nearly 90,000 new cases of cancer will be diagnosed in this...

breast cancer

Why Are Black Women Still Dying at Higher Rates Than White Women From Breast Cancer?

What is so dismaying to me is that the statistic on survival for Black women with breast cancer has not changed since I was diagnosed with breast cancer 17 years ago. In 2005, Black women were 41% more likely to die of the disease than White women, even though Black women are less likely to be...

St. Jude Receives First Group of Ukrainian Children With Cancer for Care in the United States

One month after Russia invaded Ukraine, on March 21, St. Jude Children’s Research Hospital in Memphis welcomed four Ukrainian children with cancer to be treated in the United States. Two of the children are pictured in the photos below. The four children, aged 20 months to 8 years old, traveled to...

breast cancer

Having Metastatic Breast Cancer Has Led Me to Focus on What Matters

Nothing can really prepare you for cancer, but it helped that I have dedicated my life in service to others as a minister and advocate for social justice and health equity in breast cancer survivorship. Before my own breast cancer diagnosis in 2016, I had spent years as a volunteer for several...

genomics/genetics

Results From MAPPYACTS Trial Show the Feasibility and Benefit of Molecular Profiling at Cancer Recurrence in Pediatric Patients

Despite advances in treatment for pediatric patients, cancer remains the primary cause of disease-related mortality in children and adolescents. Data from the international clinical trial MAPPYACTS, which aims to define tumor molecular profiles in pediatric patients with recurrent/refractory...

global cancer care

How ASCO, ECO, and WHO Are Marshalling Resources to Provide Care for Ukrainian Civilians and Refugees With Cancer

Since Russia invaded Ukraine on February 24, the number of attacks on health-care facilities continues to mount. According to the World Health Organization (WHO), as of March 16, there have been 43 attacks on health facilities, including 34 attacks that have directly impacted health facilities and...

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