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leukemia
lymphoma

The Leukemia & Lymphoma Society Surpasses $1 Billion Investment in Blood Cancer Research

The Leukemia & Lymphoma Society (LLS) has announced that it has passed the $1 billion mark in research investment, a significant milestone in the cancer research landscape as the Society continues its 65-year pursuit of advancing breakthrough therapies, finding cures, and ensuring access to...

Duquesne University Awarded $1.4 Million NIH Grant

Duquesne University’s newly established biomedical engineering initiative has received a $1.4 million, 5-year grant from the National Institutes of Health’s National Cancer Institute to detect, capture and analyze circulating melanoma cells. John Viator, MD, Biomedical Engineering Program Director...

issues in oncology

An Oncologic Surgeon Discusses the Pros and Cons of Pursuing a Business Degree

Is pursuing a Master of Business Administration (MBA) degree a good idea for ambitious surgical oncologists who want to advance their careers? The ASCO Post recently spoke with Martin J. Heslin, MD, MSHA, Chief, Section of Surgical Oncology, University of Alabama at Birmingham (UAB) Medical Center, ...

SIDEBAR: Research Groups in South America

Although cancer research in South America has been largely led by the pharmaceutical industry, a number of independent research groups are active in the region. Peru: GECOPERU and INEN The Peruvian Oncology Clinical Studies Group (Grupo de Estudios Clínicos Oncológicos Peruano, or GECOPERU...

global cancer care

A Vision of Independent Clinical Research in South America

Clinical research is vital for the development and improvement of methods designed to prevent and treat cancer. The majority of clinical trials take place in the developed world through sponsored pharmaceutical research companies.1 The corresponding lack of research in developing countries results...

gastroesophageal cancer

Ramucirumab for Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

On April 21, 2014, ramucirumab (Cyramza) was approved for use as a single agent in the treatment of patients with advanced or metastatic gastric or gastroesophageal junction adenocarcinoma with disease progression on or after prior treatment with fluoropyrimidine- or platinum-containing...

skin cancer

May Is National Skin Cancer Awareness Month

According to the Skin Cancer Foundation, more than 3.5 million cases of skin cancer are diagnosed each year, with the incidences of skin cancer outnumbering all cases of breast, colon, lung, and prostate cancers combined. Of the three most common types of skin cancer—basal cell carcinoma, squamous...

Connecting to ASCO Through the State Affiliate Council

ASCO’s State Affiliate Council is composed of the State Society Presidents and/or designated physician Council Representatives as well as the Executive Directors of each state and/or regional oncology society. The Council convened in late February to address the most relevant issues affecting...

SIDEBAR: How the Schwartz Center Rounds Program Works

The Schwartz Center Rounds program utilizes a case-based format to present information about an identified topic and stimulate discussion among Rounds participants. A physician leader and planning committee choose a case and topic and identify a panel of professional caregivers to share their...

issues in oncology

Schwartz Center Rounds® Programs Foster Clinical Teamwork and Enhance Patient Care

In the fall of 1994, 40-year-old ­Kenneth B. Schwartz, a health-care lawyer, was diagnosed with lung cancer. Radiation and chemotherapy failed to stop progression of the disease, and 10 months later he died. During his treatment, Mr. Schwartz wrote about the ordeal of coming to grips with the...

Irving Bone Marrow Transplant Unit Opens at NewYork-Presbyterian/Columbia

New York-Presbyterian/Columbia University Medical Center has opened the Irving Bone Marrow Transplant Unit, a state-of-the-art facility for comprehensive bone marrow transplant (BMT) care. The new unit features 18 inpatient rooms, a high-tech nurses station for individual patient monitoring, and a...

leukemia

Ofatumumab Plus Chlorambucil for Previously Untreated CLL in Patients Not Treatable With Fludarabine-Based Regimens

In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms, administration recommendations, safety profiles, and other essential information needed for the appropriate clinical use of these drugs. On April 17, 2014, ofatumumab (Arzerra) received regular approval...

Bert Howard O’Neil, MD, Joins Indiana University Simon Cancer Center

Bert Howard O’Neil, MD, has been named the inaugural Joseph W. and Jackie J. Cusick Professor of Oncology and a Professor of Medicine at the Indiana University (IU) School of Medicine, in Indianapolis. He is also the Phase I Director and Director of the Gastrointestinal Cancer Research Program at...

Becky L. DeKay, MBA, Becomes President of ACCC

Becky L. DeKay, MBA, became President of the Association of Community Cancer Centers (ACCC) at its 40th Annual National Meeting in April. She is Director of Oncology Services at the Feist-Weiller Cancer Center at Louisiana State University (LSU) Health Shreveport, in ­Louisiana.  “I am honored to...

issues in oncology
global cancer care

Personalizing Outreach to Address Asian Cancer Health Disparities

In an effort to reduce cancer health disparities among Asian Americans, UC Davis Comprehensive Cancer Center now offers individual, in-language education and culturally sensitive materials for every Asian American cancer patient. New brochures and 5-minute videos were debuted during the National...

survivorship
global cancer care

Improving Quality of Life in Cancer Survivors

The number of cancer survivors has been steadily increasing in recent years. According to the Ministry of Health National Cancer Registry, in 2010 there were 254,000 cancer survivors in Israel (3.3% of the population) compared with 15,700 (0.4% of the population, P < .005) in 1975.1 Forty years...

survivorship

Elevated Morbidity/Mortality Risks for Childhood Cancer Survivors Further Increase After Fourth Decade

An analysis of the first generation of childhood cancer survivors, who are now aging into their fourth and fifth decades, shows further increases in the survivors’ morbidity and mortality risks. “By age 50 years, more than half of survivors have experienced a severe, disabling, or life-threatening...

gynecologic cancers

Ongoing Clinical Trials Actively Recruiting Patients With Ovarian or Cervical Cancers

The information contained in this Clinical Trials Resource Guide includes details of actively recruiting clinical studies of patients with gynecologic and breast cancers. It also includes the Family Caregiver Palliative Care Intervention study, which is investigating interventions to support...

integrative oncology

Haiku: To Take Herbs or Not to?

While botanicals are generally perceived as harmless, many reports in literature indicate that misuse of botanicals can be detrimental. Presented below are a few popular herbs in use today, along with their benefits and risks, especially when taken along with other medications.   Soy...

Bookmark: Survivorship: Living Well During and After Cancer

Title: Survivorship: Living Well During and After Cancer Author: Barrie Cassileth, MS, PhD Publication Information: Spry Publishing, April 2014, 216 pages, $16.95 This slender-volume survivorship guidebook provides the latest evidence-based information on complementary therapies and is a must-read...

integrative oncology

Thirty Years of Effort Has Led to the Mainstreaming of Integrative Medicine in Oncology Care

When Barrie R. Cassileth, MS, PhD, began researching complementary medicine and its potential for use in oncology care over 30 years ago, not much was known about the importance of complementary therapies for the well-being of patients with cancer. She chose to conduct her doctoral dissertation...

American Association for Cancer Research Inaugurates New Leadership at 2014 Annual Meeting

The American Association for Cancer Research welcomed Carlos L. Arteaga, MD, as President of the Organization for 2014–2015. Dr. Arteaga was inaugurated during the AACR’s Annual Meeting. Dr. Arteaga is Professor of Medicine and Cancer Biology at Vanderbilt University School of Medicine, where he...

CancerCare Names Patricia J. Goldsmith Chief Executive Officer

CancerCare recently announced Patricia J. Goldsmith has been named the organization’s Chief Executive Officer. CancerCare is a national nonprofit organization providing free, professional support services to anyone affected by cancer. The announcement comes as the group celebrates 70 years of...

skin cancer

Genetic Testing Beneficial in Melanoma Treatment, UPCI Study Shows

Genetic screening of cancer can help doctors customize  treatments so that patients with melanoma have the best chance of beating it, according to the results of a clinical trial by researchers at the University of Pittsburgh Cancer Institute.  The trial, funded by the National Institutes of...

issues in oncology

Creating a Comprehensive Catalog of Cancer Genes to Improve Patient Outcomes

In January, Eric S. Lander, PhD, Director of the Broad Institute of MIT and Harvard in Cambridge, Massachusetts, and his colleagues published the results from their landmark study,1 which explored the feasibility of creating a comprehensive catalog of cancer genes. The researchers collected and...

thyroid cancer

Increased Incidence of Thyroid Cancer: An Epidemic of Diagnosis?

In a study reported in JAMA Otolaryngology Head & Neck Surgery,1 Davies and Welch found that the incidence of thyroid cancer has nearly tripled since 1975. However, the increase appears to represent an “epidemic of diagnosis” and to almost exclusively represent increased diagnosis of papillary...

cns cancers

Surgical Resection of Newly Diagnosed Glioblastoma: What Is the Standard of Care?

The neurosurgeon is often the gateway provider when patients present with what on magnetic resonance imaging (MRI) appears to be a new glioblastoma. Because histology-based diagnosis is a prerequisite for initiating standard therapy with radiation and chemotherapy, the first question that the...

supportive care
survivorship

Maximizing the Benefits of Exercise in Patients With Cancer

Many nonpharmacologic therapies increase both physical and emotional strength during cancer treatment as well as throughout survivorship. These therapies include the mind-body practices of meditation, self-hypnosis, guided imagery, and breath awareness, touch therapies including massage and...

palliative care

The Role of Psychosocial Supportive Services in Palliative Care

More than 2 decades ago, Deane L. Wolcott, MD, helped develop comprehensive patient-centered psycho-oncology care in cancer centers across the country. Today, many aspects of that patient-centered care, including psychiatric, dietary, pain management, cancer rehabilitation medicine, survivorship,...

cost of care

Discussions About the Cost of Cancer Care Are Still Uncommon

Patients with cancer are extremely interested in discussing the cost of treatment, especially their share of the cost, but some oncologists are still hesitant to enter into these conversations, according to a study reported at the National Comprehensive Cancer Network (NCCN) 2014 Conference.1 “We...

breast cancer
colorectal cancer
lung cancer
pancreatic cancer

ASCO Committee Defines Clinically Meaningful Goals for Clinical Trials in Pancreas, Breast, Lung, and Colorectal Cancers

The ASCO Cancer Research Committee recently convened four disease-specific working groups—in pancreas, breast, lung, and colon cancers—to “consider the design of future clinical trials that would produce results that are clinically meaningful to patients.” An ASCO perspective statement, reported in ...

myelodysplastic syndromes

Forward Progress in Myelodysplastic Syndromes Is Largely in Genetics

Most recent advances in the management of myelodysplastic syndrome (MDS) are in the area of genetics, according to Steven Gore, MD, of Yale University School of Medicine, New Haven. “New genomics research is leading to a better understanding of MDS heterogeneity and disease biology, and may...

Setting a ‘Moon Shots’ Goal to Drastically Reduce Cancer Mortality Over the Next Decade

In 2012, just 1 year after taking the reins as President of The University of Texas MD Anderson Cancer Center, Ronald A. DePinho, MD, announced his plans to launch the Moon Shots Program, the most ambitious endeavor undertaken by the cancer center to dramatically accelerate the pace of reducing...

James P. Allison, PhD, Receives 2014 Canada Gairdner International Award

The Gairdner Foundation of Canada has named James P. Allison, PhD, for one of its 2014 Canada Gairdner International Awards. Dr. Allison is Chair and Professor of Immunology at The University of Texas MD Anderson Cancer Center in Houston. The honor, announced recently by the Gairdner Foundation,...

AACR Honors Douglas Hanahan, PhD, With AACR Lifetime Achievement in Cancer Research Award

Douglas Hanahan, PhD, Director of the Swiss Institute for Experimental Cancer Research at the Swiss Federal Institute of Technology, in Lausanne, Switzerland, was recently honored with the 11th annual American Association for Cancer Research (AACR) Lifetime Achievement in Cancer Research. The award ...

hematologic malignancies

Shelagh Tippet-Fagyas Named President of The Leukemia &amp; Lymphoma Society of Canada

The Leukemia & Lymphoma Society recently announced that its Canadian affiliate, The Leukemia & Lymphoma Society of Canada, has named Shelagh Tippet-Fagyas as its new President. Ms. Tippet-Fagyas will lead the Canadian Society in its efforts to find cures and ensure access to therapies for...

Help Your Patients Understand the Latest Research to be Highlighted at the 2014 ASCO Annual Meeting

Direct your patients to Cancer.Net, ASCO’s patient information website, to find easy-to-read summaries of studies released on May 14 in advance of this year’s Annual Meeting. In addition, encourage them to listen to a panel discussion and Q&A session about these latest advances in a recording...

Visit the Conquer Cancer Foundation Donor Lounge at the ASCO Annual Meeting

The work that we do at the Conquer Cancer Foundation would not be possible without the support of generous donors who share our vision to create a world free from the fear of cancer. Conquer Cancer Foundation supporters are invited to visit the Donor Lounge during the ASCO Annual Meeting, held May...

ASCO Launches New Resources for Providers and Patients to Address Link Between Obesity and Cancer

As the obesity epidemic takes its toll on the nation’s health, ASCO is making strides to address this growing concern as it relates to cancer. ASCO has developed a suite of educational resources designed to help oncology providers educate their patients about the negative effects of obesity on...

Conquer Cancer Foundation of ASCO Young Investigator Award Recipients Supported by the Strike 3 Foundation

Sarah K. Tasian, MD (2011 Young Investigator Award) The Children’s Hospital of Philadelphia Predicting Biochemical and Genetic Responses to JAK Inhibitor Therapy in Patients With CRLF2-Overexpressing Acute Lymphoblastic Leukemia Kasey Leger, MD (2012 Young Investigator Award) University of...

Conquer Cancer Foundation and Strike 3 Foundation Work Together to Conquer Pediatric Cancers

Envision a world where a diagnosis of pediatric cancer is met with the same reaction as a diagnosis of the common cold. In this idyllic world, the word “cancer” no longer carries with it the same traumatic response or stigma that it does today.  This hopeful vision is what drives Craig Breslow in...

global cancer care

American Society of Clinical Oncology Honors Researchers, Patient Advocates, and Leaders of the Global Oncology Community

Leaders in cancer care will be recognized as part of the American Society of Clinical Oncology Special Awards Program at the 2014 ASCO Annual Meeting. The Special Awards recognize the dedication and significant contributions of researchers, patient advocates, and leaders of the global oncology...

Centers for Disease Control and Prevention Awards Grants of More Than $1.25 Million to College of American Pathologists

The College of American Pathologists (CAP) has been awarded two grants from the Centers for Disease Control and Prevention (CDC). The funding, totaling more than $1.25 million, will be used to improve the adoption of evidence-based laboratory testing guidelines and to standardize reporting of...

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Announces Faculty Appointments, Grants

Noah M. Hahn, MD, has been selected as Associate Professor of Oncology and Urology at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins in Baltimore. Before joining Johns Hopkins, Dr. Hahn was the Director of the Genitourinary Medical Oncology Program at Indiana University. He is an...

issues in oncology

Project Data Sphere: Megadata in the Cloud Could Speed Clinical Trials Here on Earth

Project Data Sphere, which launched on April 8, is a “giant digital laboratory, an enormous library containing data about tens of thousands of patients and hundreds of clinical trials, all of which will be in the public domain,” said Martin J. Murphy, Jr, DMedSc, PhD, FASCO, Chief Executive Officer ...

Michael S. Gordon, MD, Named Medical Director for Virginia G. Piper Cancer Center Clinical Trials at Scottsdale Healthcare

Michael S. Gordon, MD, has been named the new Medical Director for the Virginia G. Piper Cancer Center Clinical Trials program at Scottsdale Healthcare in Phoenix. Dr. Gordon will oversee the center’s phase I clinical trials program. Virginia G. Piper Cancer Center Clinical Trials at Scottsdale...

Researchers Cornelia Ulrich, PhD, and Bruce A. Edgar, PhD, Join Huntsman Cancer Institute

Cornelia Ulrich, PhD, and Bruce A. Edgar, PhD, scholars in the fields of cancer prevention and molecular biology, respectively, will join Huntsman Cancer Institute at the University of Utah as early as September 1, 2014. Dr. Ulrich is currently serving as a Director of the National Center for...

pain management

Phase III Trial Reports Focused Ultrasound Reduces Cancer Pain

A phase III clinical trial has shown that noninvasive magnetic resonance-guided focused ultrasound treatment that heats the cancer within the bone, relieves pain and improves function for most patients when other treatment options are limited. The results were published recently in the Journal of...

colorectal cancer

Getting It Right in the End: Individualization of Care for Patients With Rectal Cancer

Data from trials conducted mostly in the 1970s and 1980s established the paradigm that optimal treatment of rectal cancer requires a combination of radiation therapy, chemotherapy, and surgery.1 Virtually all of these trials, however, demonstrated that radiotherapy added only to the local control...

colorectal cancer

Neoadjuvant Chemotherapy Without Routine Radiotherapy Shows Promise in Patients With Locally Advanced Rectal Cancer

In a pilot study reported in the Journal of Clinical Oncology, Deborah Schrag, MD, MPH, and colleagues from Memorial Sloan Kettering Cancer Center, New York, assessed outcomes with neoadjuvant FOLFOX (fluorouracil, leucovorin, oxaliplatin)/bevacizumab (Avastin) with selective use of...

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