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Stay Up to Date on New Patient Materials From Cancer.Net

Encourage your patients to use social media to stay up to date with the new resources available on Cancer.Net. It is easier than ever for patients to get the latest cancer information on their computer or mobile device. Subscribe to the Cancer.Net Blog at www.cancer.net/blog; connect to...

Researcher Spotlight: Conquering Cancer With Emily Ko, MD, MSCR

One of the best ways to prevent cancer is by finding new, better treatments for conditions that are considered risk factors. That is why Emily Ko, MD, MSCR, Assistant Professor of Obstetrics and Gynecology at the University of Pennsylvania School of Medicine, is investigating a new method for...

solid tumors

Current Progress Against Cancer and What Lies Ahead in the Next Decade

In January, ASCO released its report, Clinical Cancer Advances 2015: An Annual Report on Progress Against Cancer,1 which details research advances over the past decade that have led to longer survival and better quality of life for the more than half-a-million people diagnosed with cancer each...

Jim Hu, MD, Joins NewYork-Presbyterian Hospital and Weill Cornell Medical College

Jim Hu, MD, has been appointed Director of the LeFrak Center for Robotic Surgery at NewYork-Presbyterian/Weill Cornell Medical Center and recruited as the Ronald Lynch Chair of Urologic Oncology at Weill Cornell Medical College. He assumed his new role on February 1. Dr. Hu is an expert in the use...

global cancer care

Global Oncology Launches Global Cancer Project Map With NCI

Nonprofit Global Oncology, Inc (GO) announced the launch of the Global Cancer Project Map, a novel online resource and virtual information exchange connecting the global cancer community. Developed by Global Oncology in collaboration with the National Cancer Institute (NCI) Center for Global...

bladder cancer

Adjuvant Chemotherapy and Overall Survival in Muscle-Invasive Bladder Cancer: Still Climbing the Mountain

Muscle-invasive bladder cancer can be a lethal disease despite curative intent local therapy, with 5-year survival that can be as low as 30% based on the extent of T status and/or lymph node involvement. The use of neoadjuvant chemotherapy with MVAC (methotrexate, vinblastine, doxorubicin, and...

NCCN Honors Joseph V. Simone, MD,  FASCO, and John A. Gentile, Jr, at Group’s 20th Annual Conference

At the National Comprehensive Cancer Network (NCCN) 20th Annual Conference held last month in Hollywood, Florida, NCCN honored Joseph V. Simone, MD, FASCO, and John (Jack) A. Gentile, Jr, with the NCCN Board of Producers Award. Dr. Simone is President of Simone Consulting Company, which advises...

Michael H. Levy, MD, PhD, Receives Lifetime Achievement Award

Michael H. Levy, MD, PhD, Director of the Pain and Palliative Care Program at Fox Chase Cancer Center, and one of the founding leaders of the American hospice and palliative care movement, has received the Lifetime Achievement Award from the American Academy of Hospice and Palliative Medicine...

EMPEROR Science Award Program

Stand Up To Cancer (SU2C) and PBS LearningMedia announced The ­EMPEROR Science Award Program. This initiative will encourage students from disadvantaged high schools to pursue careers in science, with a particular emphasis on cancer research, through a year of mentorship with a scientist from a...

breast cancer

Breast Cancer Management in Review

Anyone who has attended the major oncology meetings knows that research from clinical trials in breast cancer often dominates the stage, with countless abstracts featuring new and updated results. To help the readers of The ASCO Post stay up to date with the latest discoveries and findings...

James P. Allison, PhD, Wins 2015 Paul Ehrlich and Ludwig Darmstaedter Prize

James P. Allison, PhD, Chair of Immunology at The University of Texas MD Anderson Cancer Center, has received the 2015 Paul Ehrlich and Ludwig Darmstaedter Prize in recognition of his work in the field of immunotherapy. “In immunotherapy, it’s not the tumor but the immune system that is targeted....

lung cancer

FDA Approves Nivolumab to Treat Metastatic Squamous NSCLC

The U.S. Food and Drug Administration (FDA) has approved the PD-1 inhibitor nivolumab (Opdivo) for the treatment of patients with metastatic squamous non–small cell lung cancer (NSCLC) who have progressed on or after platinum-based chemotherapy. Nivolumab is a monoclonal antibody that binds to the...

issues in oncology
supportive care

FDA Approves First Biosimilar Product Filgrastim-Sndz

The U.S. Food and Drug Administration (FDA) has approved filgrastim-sndz (Zarxio), the first biosimilar product approved in the United States. A biosimilar product is a biologic product that is approved based on a showing that it is highly similar to an already-approved biologic. The biosimilar...

lung cancer

Results of RTOG 0617 Reconsidered

Radiation Therapy Oncology Group (RTOG) 0617 was a study initially designed to address an important issue in radiation oncology regarding the treatment of stage III non–small cell lung cancer (NSCLC): Are outcomes improved with high-dose as opposed to standard-dose thoracic radiation therapy? The...

issues in oncology
lung cancer

New Tobacco Atlas Details Scale and Harm of the Tobacco Epidemic

The Tobacco Atlas, fifth edition, its companion mobile app, and website TobaccoAtlas.org, were released by the American Cancer Society and World Lung Foundation at the 16th World Conference on Tobacco or Health held March 17–21, 2015 in Abu Dhabi, United Arab Emirates. The Atlas details the scale...

health-care policy
legislation

State Oncology Societies Join ASCO’s Call on Congress to Replace SGR Formula

In a show of solidarity, state oncology societies from across the United States joined ASCO in its call on Congress to repeal Medicare’s Sustainable Growth Rate (SGR) formula before the current payment patch expires. In a letter to U.S. House and Senate leadership, 48 signatories, representing tens ...

issues in oncology
lung cancer

NCCN Publishes New Guidelines for Smoking Cessation

Tobacco-related diseases are the most preventable cause of death worldwide. According to the American Cancer Society, in 2015, nearly 171,000 of the estimated 589,430 cancer deaths in the United States—more than 25%—will be caused by tobacco smoking. Smoking cessation leads to improvement in cancer ...

prostate cancer

Evidence Mounts for Clinical Utility of AR-V7 in Treatment Selection for Advanced Prostate Cancer

The search is on in prostate cancer to identify predictive and prognostic biologic and genomic markers that go beyond traditional ones. Several groups are working in this area. One marker that has received much attention is a splice abnormality in the androgen receptor (AR) called AR-V7. Two...

health-care policy

ASCO Commends U.S. House of Representatives for Voting to Repeal the SGR, Urges Senate to Pass Legislation

We applaud the House of Representatives for passing legislation that eliminates the Sustainable Growth Rate [SGR] formula and takes a giant leap toward meaningful and urgently needed Medicare physician payment reform. Cancer incidence among Medicare beneficiaries is expected to increase by 67% by...

breast cancer
issues in oncology

Too Early to Use Genome Sequencing for Breast Cancers in the Clinic

The role of next-generation sequencing (high-throughput technologies that allow DNA and RNA to be analyzed more quickly and inexpensively than earlier techniques) in breast cancer remains unclear and at present is primarily a research tool. Therefore, clinicians should be cautious in using genetic...

breast cancer

Understanding the Role of Immune Function in the Treatment of HER2-Positive Breast Cancer

The addition of trastuzumab (Herceptin) to adjuvant chemotherapy undoubtedly transformed HER2-positive breast cancer from one of the most deadly subtypes to a highly treatable disease. Randomized phase III trials established adjuvant trastuzumab as standard of care in HER2-positive breast...

issues in oncology

Clinical Trial Participation: ‘Is It All Worth It?’

Clinical trials have become increasingly complex over the past several years, and unfortunately, this has resulted in the typical scenario described below. We are fortunate that there are so many promising agents available for patients, and we want to encourage their participation in clinical...

kidney cancer

No Survival Benefit From Adjuvant Sorafenib or Sunitinib in Kidney Cancer

Adjuvant therapy with sorafenib (Nexavar) or sunitinib (Sutent) failed to make any inroads in improving disease-free survival in patients with locally advanced kidney cancer in the randomized, placebo-controlled, multicenter, phase III Adjuvant Sorafenib and Sunitinib for Unfavorable Renal...

The ASCO Post Replies

Nivolumab (Opdivo) was approved by the U.S. Food and Drug Administration (FDA) for the treatment of lung cancer on March 4, 2015, before clinical data from the pivotal trials (CheckMate 017 and CheckMate 063) were presented at a major oncology conference or published in a peer-reviewed journal....

lung cancer

Nivolumab in Lung Cancer

I find The ASCO Post to be a good way to hear about new ideas that I might otherwise have missed. I read an article recently about the approval of nivolumab (Opdivo) for treating metastatic squamous non-small cell lung cancer (The ASCO Post, April 10, 2015). I thought it would have been much more...

prostate cancer

Widespread Use of Docetaxel Preceded Phase III Evidence of Usefulness in Patients With Metastatic Prostate Cancer

Docetaxel was being widely used by patients with metastatic prostate cancer before phase III evidence that it was more effective than the standard of care for patients with castration-resistant prostate cancer, according to an analysis of Medicare claims from before and after the trial results and...

Expect Questions About Cold Caps to Spare Hair During Chemotherapy

For patients who have confronted a diagnosis of cancer, then endured weeks of chemotherapy, it would seem that losing their hair would not be a big concern. But for many patients, it can be. “You have to spend a year either putting on wigs or announcing to the world that you’ve had chemotherapy,”...

symptom management

Scalp Cooling Caps Offer Option to Prevent Hair Loss During Chemotherapy

Hair loss remains one of the most dreaded side effects of chemotherapy, particularly for women. Scalp cooling caps worn by patients during chemotherapy infusion and for brief periods of time before and after offer these patients an option to preserve 50% or more of the hair on their heads. Although ...

2015 Canada Gairdner Awards Honor Top Medical Researchers Worldwide

The Gairdner Foundation named the winners of the 2015 Canada Gairdner Awards, recognizing some of the most significant medical discoveries around the world. The awards provide a $100,000 (CAD) prize to each scientist for his or her work. The aim of the Gairdner Awards is to promote a culture of...

2015 Oncology Meetings

MAY International Society of Geriatric Oncology (SIOG): Cancer Care of the Older Adult Across the Cancer ContinuumMay 1 • New York, New York For more information: www.siog.org 1st Annual New Treatments in Oncology Conference (ANTO)May 1-2 • Scottsdale, Arizona For more information:...

Patient Guides Available Through ASCO University Bookstore

ASCO Answers: Managing the Cost of Cancer Care explains the various costs associated with cancer treatment, including health-care coverage through the Affordable Care Act. It also provides a list of financial resources available to help offset expenses related to care and tips for organizing...

AACR Honors Cancer Pioneers at the 2015 Annual Meeting

The American Association for Cancer Research (AACR) recognized six oncologists making valuable contributions to their fields with awards at the Association’s Annual Meeting 2015, held in Philadelphia from April 18–22. William C. Hahn, MD, PhD, was awarded with the 39th Annual AACR–Richard and Hinda ...

Lewis C. Cantley, PhD, Honored With AACR Memorial Lectureship

The American Association for Cancer Research (AACR) honored Lewis C. Cantley, PhD, with the 9th Annual Princess Takamatsu Memorial Lectureship at the AACR Annual Meeting 2015. Dr. Cantley is the Meyer Director of the Sandra and Edward Meyer Cancer Center, the Margaret and Herman Sokol Professor in...

issues in oncology

Dana-Farber President and CEO Edward J. Benz, Jr, MD, to Retire in 2016

Dana-Farber President and CEO Edward J. Benz, Jr, MD, has announced he will retire from the Dana-Farber Cancer Institute (DFCI) in 2016, after 16 years running the organization. Dr. Benz will also vacate the positions as Director and Principal Investigator of the Dana-Farber/Harvard Cancer Center...

Robert H. Lurie Names Associate Director for Administration

Aleksandar Zafirovski, MBA, has been named Executive Administrative Director and Associate Director for Administration for the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. He has served as Interim Associate Director since 2014. Mr. Zafirovski has previously been...

issues in oncology

Richard Gilbertson, MD, PhD, Leaves St. Jude Children’s Research Hospital

St. Jude Children’s Research Hospital announced the departure of Scientific and Comprehensive Cancer Center Director, Richard Gilbertson, MD, PhD. Dr. Gilbertson will be Director of the Cambridge Cancer Centre at the University of Cambridge. Since joining St. Jude in 2000, Dr. Gilbertson has led...

Recipients of the 2015 Conquer Cancer Foundation’s Innovation Grants

The Conquer Cancer Foundation’s 2015 International Innovation Grants were awarded to the following five organizations conducting research in India, Mexico, Nigeria, Romania, and Uganda: Tata Medical Center (Kolkata, India). This grant is funding a randomized clinical study testing the success of...

Owen N. Witte, MD, Recognized With AACR G.H.A. Clowes Memorial Award

The American Association for Cancer Research (AACR) honored Owen N. Witte, MD, Founding Director of the Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, and Distinguished Professor of Microbiology, Immunology, and Molecular Genetics at the University of California,...

multiple myeloma

FDA Grants Priority Review to Carfilzomib Supplemental New Drug Application for Relapsed Multiple Myeloma

The U.S. Food and Drug Administration (FDA) has accepted Amgen’s supplemental New Drug Application (sNDA) for carfilzomib (Kyprolis) injection for the treatment of patients with relapsed multiple myeloma who have received at least one prior therapy. The sNDA is designed to support the conversion of ...

gynecologic cancers

FDA Grants Breakthrough Therapy Designation to Rucaparib in Advanced Ovarian Cancer With BRCA Mutations

The U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to Clovis Oncology’s investigational agent rucaparib as monotherapy treatment of advanced ovarian cancer in patients who have received at least two lines of prior platinum-containing therapy, with ­BRCA-mutated ...

breast cancer

Ann Partridge, MD, MPH, Confronts Challenges Facing Young Women With Breast Cancer With Support From Conquer Cancer Foundation Improving Cancer Care Grant

Ann Partridge, MD, MPH, Associate Professor of Medicine at Harvard Medical School and Founding Director of the Program for Young Women With Breast Cancer at the Dana-Farber Cancer Institute, received a 2010 Improving Cancer Care Grant (ICCG) for her project “Improving the Care of Young Women with...

ASCO’s Oncology Interoperability Standard Highlighted in AMIA’s Bioinformatics Journal Club Webinar

ASCO’s oncology-specific interoperability electronic data-sharing standard for communicating and coordinating care throughout the cancer journey was featured in the American Medical Informatics Association’s Bioinformatics Journal Club webinar, a live production jointly sponsored by the Division of ...

FDA’s Biosimilar Product Approval Process: A Closer Look

In March, the U.S. Food and Drug Administration (FDA) approved filgrastim-sndz (Zarxio) as a biosimilar to U.S.-licensed filgrastim (Neupogen). It is the first biosimilar product to be approved in the United States and will increase treatment options for people living with cancer. The FDA considers ...

global cancer care

Researcher Spotlight on Conquer Cancer Foundation International Innovation Grant Recipient Mya Thida, MBBS

In 2014, Mya Thida, MBBS, of Myanmar, was awarded one of the first-ever Conquer Cancer Foundation of ASCO International Innovation Grants. This grant was created to fund novel research projects that may significantly improve cancer control in low- and middle-income countries. One year later, Dr....

global cancer care

Cancer Control in Primary Care Courses Offered in India

ASCO International’s mission is to optimize care for every patient with cancer in the world. To achieve that goal, it is critical to establish collaborations in all sectors of the health-care system. ASCO International’s newest course, Cancer Control in Primary Care, helps to address this need by...

Direct Your Patients to Cancer.Net for Informative Videos

Cancer.Net offers patient-friendly videos produced by ASCO to give people with cancer and their families and friends an additional option for oncologist-approved information. Topics covered include side effects, treatments, tests and procedures, quality of life, survivorship, cancer research news,...

breast cancer

Triple Negative Breast Cancer Foundation Works to Change the Treatment Landscape of an Aggressive Form of Breast Cancer

Hayley Dinerman, Cofounder and Executive Director of the Triple Negative Breast Cancer Foundation, remembers how she and a group of close female friends first learned about the devastating effects of triple-negative breast cancer. It was 2005 when these new mothers, who had recently formed a...

Michael E. Jung, PhD, Charles Sawyers, MD, and Howard I. Scher, MD, Receive Team Science Award From American Association for Cancer Research

Michael E. Jung, PhD, Distinguished Professor of Chemistry and Biochemistry and Member at UCLA Jonsson Comprehensive Cancer Center; Charles Sawyers, MD, Human Oncology and Pathogenesis Program Director at Memorial Sloan Kettering Cancer Center; and Howard I. Scher, MD, Chief of the Genitourinary...

geriatric oncology

Preparing for the ‘Silver Tsunami’ and the Impact of an Aging Population on Cancer Care

“Older adults constitute the only increasing natural resource in the entire world.” —Linda Fried, PhD, Columbia School of Public Health The good and bad news about our changing demographic world is that the population of older adults is increasing in the United States and worldwide. While it is...

issues in oncology
cost of care

In Search of ‘Just’ Prices: Questioning the High Cost of New Cancer Drugs

As the oncology community begins the slow and often difficult-to-define transition from volume to value in the delivery of cancer care, the relationship between the price and value of certain high-priced cancer drugs is getting more scrutiny. We generally correlate the efficacy of a new drug and...

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