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gynecologic cancers

Key Guideline Recommendations

Human papillomavirus (HPV) DNA testing is recommended in all resource settings; visual inspection with acetic acid (VIA) may be used in the basic setting as a “stepping stone” that helps build health service capacity until HPV testing becomes available. Although cotesting with HPV and Papanicolaou...

gynecologic cancers

ASCO Issues Global Recommendations to Increase Cervical Cancer Screening

Earlier this month, ASCO issued a new global guideline on screening for cervical cancer.1 The guideline provides evidence-based recommendations for screening, follow-up of positive screening results, and treatment of women with cervical precancers in countries worldwide.  ASCO’s guideline...

National Heart, Lung, and Blood Institute Selects Moffitt Cancer Center as One of Five Cell Therapies Processing Facilities

Moffitt Cancer Center has been selected as a Cell Therapies Processing Facility by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health. Moffitt is one of five institutions that make up the NHLBI’s Production Assistance for Cellular Therapies group. The...

cost of care
issues in oncology

Study Finds African American Cancer Survivors More Likely to Experience Lasting Debt Related to Cancer and Its Treatment

African American cancer survivors are more likely than whites to experience lasting debt or forgo necessary medical care as they struggle with the financial burden of cancer, whereas white cancer survivors are somewhat more likely to use existing assets to pay for their cancer care, according to a...

cost of care
issues in oncology
health-care policy

Affordable Care Act Increased Access to Cancer Care and Clinical Trial Participation Among Hispanics in California

Implementation of the Affordable Care Act may have led to a significant increase in the number of Hispanic breast cancer patients treated in California at a National Cancer Institute (NCI)-designated cancer center. Further, there was also an increase reported in the number of Hispanic women who...

Face Mask for Radiation Therapy

By the 1930s, the dangers of radiation were well known. American Martyr’s to Science Through the Roentgen Rays, published in 1936, documented the dead heroes of American radiology, from Clarence Daly, Thomas Edison’s associate, to Elizabeth Fleischman, the only woman in the group, who was a U.S....

2016-2017 Oncology Meetings

OCTOBER 16th Biennial Meeting of the International Gynecologic Cancer SocietyOctober 29-31 • Lisbon, PortugalFor more information:http://igcs2016.com NOVEMBER 2016 Oncofertility Conference: Expanding Access to Emerging and Existing Oncofertility ServicesNovember 1-3 • Chicago, Illinois For more...

issues in oncology

New American Cancer Society Report Reveals Gaps, Identifies Unique Barriers in Pediatric Cancer Research

A first-of-its-kind joint report from the American Cancer Society and the Alliance for Childhood Cancer has compiled the latest information related to pediatric cancer, including statistics and trends; a current list of drugs used to treat pediatric cancers; ongoing pediatric cancer clinical...

Lombardi’s Ruesch Center Policy Briefing Features Strategies to Reduce Costs

Two major developments in oncology—the dramatic success of some immunotherapies and targeted drugs and an equally dramatic rise in the cost of care—have created policy issues, more serious than ever, regarding access to care. It is a time “of extraordinary opportunities combined with inequities in ...

A Cancer Diagnosis Brings Two Sisters Back Together

Elizabeth Lesser is an award-winning writer and co-founder of the Omega Institute, the largest adult education center in the United States focusing on health, wellness, spirituality, and creativity. She is the author of several acclaimed books including Broken Open: How Difficult Times Can Help...

Cedars-Sinai Appoints Robert A. Figlin, MD, to Lead New Initiative to Integrate Cancer Care Across Health System

Cedars-Sinai recently announced it has appointed Robert A. Figlin, MD, to integrate research and clinical strategies across the organization in an effort to standardize cancer care and ensure optimal treatment of patients. Dr. Figlin will serve as Deputy Director of the Integrated Oncology Service ...

breast cancer
symptom management

Dexamethasone Mouth Rinse Should Be Routine Part of Everolimus Treatment

Dexamethasone mouth rinse should be given prophylactically to prevent stomatitis associated with everolimus (Afinitor)/exemestane in metastatic breast cancer, according to Hope S. Rugo, MD, principal investigator of the SWISH trial and Director of Breast Oncology and Clinical Trials Education at...

hematologic malignancies
palliative care

Palliative Care Still in Its Infancy in Hematologic Malignancies

Palliative care is slowly but surely being integrated into the treatment of patients with solid tumors, but its role in the hematopoietic stem cell transplant setting is still lagging, speakers said at the 2016 Palliative Care in Oncology Symposium. “There is a huge symptom burden among patients...

gastrointestinal cancer

New NCCN Patient Resources Assist Decision-Making for Patients With Stomach Cancer

According to the American Cancer Society, it is estimated that more than 26,000 people will be diagnosed with stomach cancer in the United States this year, with nearly 1 million new cases diagnosed worldwide each year, according to the World Health Organization. Because there are no early symptoms ...

genomics/genetics

Using Pharmacogenetics to Predict Cancer Prognosis, Response to Treatment, and Toxicity

Although clinical trials are helpful in determining the effectiveness of a specific drug across a patient population, they are not as reliable at pinpointing how well a particular patient will respond to the drug or dosing regimen or how the drug may impact the patient’s quality of life from...

colorectal cancer

ESMO 2016: Longer Interval Between Preoperative Chemoradiotherapy and Surgery Urged in Locally Advanced Rectal Cancer

A longer waiting interval from the end of preoperative chemoradiotherapy to surgery increases the rate of pathologic complete response and yields a higher proportion of patients achieving tumor downstaging in patients with locally advanced rectal cancer, according to new findings from a...

Sanford Research in South Dakota Receives NIH Grant in Head and Neck, Pediatric Cancers

The Cancer Biology Research Center at Sanford Research in Sioux Falls, South Dakota, is the recipient of a 5-year, nearly $11.7 million grant from the National Institutes of Health (NIH) to translate laboratory research into clinical trials for head and neck and pediatric cancers. The grant was...

head and neck cancer

Rise in Oropharyngeal Cancer Incidence in the UK Not Solely Driven by HPV

The rise in the incidence of oropharyngeal squamous cell carcinoma in the United Kingdom from 2002 to 2011 was not solely attributable to a rise in the incidence of human papillomavirus (HPV)-positive disease, according to a study published in Cancer Research,1 which reported that the proportion of ...

colorectal cancer

ESMO 2016: Dabrafenib/Trametinib/Panitumumab Improves Efficacy in BRAF Mutation–Positive Metastatic Colorectal Cancer

Patients with metastatic colorectal cancer and tumors harboring the BRAF V600E mutation who received triple therapy with dabrafenib (Tafinlar), trametinib (Mekinist), and panitumumab (Vectibix) showed an improved best overall response and prolonged progression-free survival compared to...

issues in oncology

Barriers and Opportunities Reported in the Study of Human Papillomavirus Education and Immunization Efforts

Human papillomavirus (HPV) vaccination rates remain low across the United States, with fewer than 40% of girls and just over 21% of boys receiving the recommended vaccine series. Research from Roswell Park Cancer Institute has identified barriers that need to be overcome to improve vaccination...

solid tumors
hematologic malignancies

ESMO 2016: Vemurafenib Shows Clinical Benefit in Diverse BRAF V600–Mutated Tumors

Findings from a phase II trial of vemurafenib in previously treated patients with advanced disease and BRAF-mutated tumors indicate that the drug is effective in patients with diverse BRAF V600­–mutated tumors but not in patients with BRAF non-V600 mutations. After a mean treatment...

When Breath Becomes Air: Dr. Lucy Kalanithi Reflects on Dr. Paul Kalanithi’s Life and Writing

Perhaps more than any other book in recent memory, When Breath Becomes Air has struck a chord among readers, both inside the medical community and among the public, desiring an honest and philosophical consideration of death. The autobiographical account of Paul Kalanithi, MD, a physician diagnosed ...

ASCO Answers Palliative Care: A Resource for Patients

ASCO Answers Palliative Care is an informative booklet that shows how palliative care is used to manage symptoms and side effects; help with practical concerns; address spiritual questions; and support family, friends, and caregivers at any stage of cancer. It also gives practical advice about...

Leave a Legacy of Hope

By including a planned gift to the Conquer Cancer Foundation in your estate plans, you can help make a dramatic difference for cancer patients years—even decades—into the future. With just one small change to your will or trust, your planned gift of any size will deliver a big impact, and: Your...

Arti Hurria, MD: From Leadership Development Program to Board of Directors

Arti Hurria, MD, a geriatric oncologist at City of Hope in Duarte, California, is the first graduate of ASCO’s Leadership Development Program to be elected to ASCO’s Board of Directors. Within 5 years of completing the program, Dr. Hurria went from learning leadership skills to applying them to...

New Member Categories Provide Specialized Support to Cancer Care Team Members

As part of ASCO’s ongoing effort to fully support all members of the cancer care team, it recently created three new member categories: Advanced Practice Providers, Practice Administrators, and Patient Advocates (see sidebar). Originally part of the Affiliated Health Professionals member category, ...

ASCO Presents First-Ever ASCO Congressional Leadership Award to Representative Michael Burgess, MD

ASCO presented Representative Michael Burgess, MD (TX-26) with the Society’s first-ever ASCO Congressional Leadership Award to recognize his steadfast work to advance policies that support cancer research and treatment. This new, annual award honors a Member of Congress who is a dedicated champion ...

Free PQRS Reporting Now Available Through QOPI®; No Additional Reporting Required

ASCO is pleased to announce that oncology practices can now complete all of their Physician Quality Reporting System (PQRS)1 requirements through the Quality Oncology Practice Initiative (QOPI®) platform. All users will be able to use the QOPI system to fulfill the Oncology Measures Group set of 7...

pancreatic cancer

Precision Promise Clinical Trial Focuses on Precision Medicine, Collaboration, and Data-Sharing in Pancreatic Cancer

The Pancreatic Cancer Action Network recently announced Precision Promise, the first large-scale precision medicine trial designed to transform outcomes for patients with pancreatic cancer. The organization also announced the 12 initial Precision Promise Clinical Trial Consortium sites selected to...

St. Jude Children’s Research Hospital and Sanger Institute, UK Agree to Full Exchange of Cancer Data

St. Jude Children’s Research Hospital and the Wellcome Trust Sanger Institute, UK, have agreed to a full exchange of cancer mutation data to support the discovery and understanding of genetic mutations causing cancers. The agreement will provide regular updates and exchanges of data between both...

gynecologic cancers

What We Know and What We Need to Know About Neoadjuvant Chemotherapy in Advanced Ovarian Cancer

Ever since the landmark studies of Griffiths and colleagues in the 1970s,1 primary cytoreductive surgery followed by chemotherapy with the objective of achieving minimal residual disease has been the standard approach for women with advanced-stage epithelial ovarian cancer. However, what is...

gynecologic cancers

SGO and ASCO Clinical Practice Guideline on Neoadjuvant Chemotherapy for Newly Diagnosed Advanced Ovarian Cancer

As reported by Alexi A. Wright, MD, MPH, of Dana-Farber Cancer Institute, and colleagues in the Journal of Clinical Oncology, ASCO and the Society of Gynecologic Oncology (SGO) have released a clinical practice guideline on neoadjuvant therapy for patients with newly diagnosed stage IIIC or IV...

Expert Point of View: Olivier Michielin, MS, MD, PhD

The paper’s invited discussant was Olivier Michielin, MS, MD, PhD, Head of Personalized Analytical Oncology and the Melanoma Clinic at Lausanne University Hospital in Switzerland. He called the findings of the European Organisation for Research and Treatment (EORTC) 18071 trial a “new landmark in...

Quality Science at ESMO 2016

Andrés Cervantes, MD, PhD, Scientific Chair of the 2016 European Society for Medical Oncology (ESMO) Congress, concluded the meeting earlier this month by recognizing a number of important take-home messages. At a closing press conference, Dr. Cervantes noted that the “ESMO 2016 Congress has...

Mount Sinai and Thomas Jefferson University Researchers Receive Falk Foundation Grant to Study Uveal Melanoma

Uveal melanoma is the second most common type of skin cancer. Approximately 50% of patients with uveal melanoma will develop metastasis, most commonly to the liver. The disease can appear more than 10 years after the primary lesion has been removed, lying dormant for long periods. There are...

UPMC Honors Stanley M. Marks, MD, With Endowed Chair in Hematology/Oncology Leadership

The University of Pittsburgh Medical Center (UPMC) announced that Stanley M. Marks, MD, oncologist and advocate for cancer patients throughout the western Pennsylvania region, is being honored by the UPMC and his medical partners at Oncology Hematology Association (OHA) through the establishment...

Huntsman Cancer Institute Names Ben Tanner Executive Director

University of Utah Health Care (UUHC) has named Ben ­Tanner, Huntsman Cancer Institute’s current Director of Clinical Operations and Chief Operating Officer (COO), as the Institute’s Executive Director, replacing Ray Lynch, who is retiring after 13 years of service. Mr. Tanner has been COO of the...

head and neck cancer

With Changing Strategies for Laryngeal Cancer, Multidisciplinary Team Approach Is Key

The treatment of cancer of the larynx has changed dramatically in recent years. With organ preservation now possible in many cases, it is more important than ever for patients to receive guidance from every corner of the field. In a recent article in the Journal of Oncology Practice (JOP),1 a...

health-care policy

NIH Expands National Precision Medicine Initiative Cohort Program

The National Institutes of Health (NIH) has announced awards to add four regional medical center groups to the national network of health-care provider organizations that will implement the Precision Medicine Initiative Cohort Program. Combined, the new health-care provider organizations will...

German Society Salutes ‘Big Four’ for Pioneering Work in Women’s Health Care

Diethelm Wallwiener, MD, President of the German Society for Gynaecology and Obstetrics, announced “The Big Four of the Millennium” at the 61st Congress of the Society, held recently in Stuttgart, Germany. The award recognizes individuals’ whose work in the 20th century created the standards of...

breast cancer

Breast Cancer Study Finds Higher Mortality Rate in Black Women Than White Women, and the Disparity Is Growing

The Avon Foundation for Women recently released a new study on the racial disparities in breast cancer mortality in the 50 largest cities in the United States between 2005 and 2014. Published in Cancer Epidemiology,1 the study was conducted by Sinai Urban Health Institute in collaboration with the...

sarcoma

FDA Grants Accelerated Approval to Olaratumab for Treatment of Advanced Soft-Tissue Sarcoma

Today, the U.S. Food and Drug Administration (FDA) granted accelerated approval to olaratumab (Lartruvo) in combination with doxorubicin to treat adults with certain types of soft-tissue sarcoma. Olaratumab is approved for use with the FDA-approved chemotherapy drug doxorubicin for the treatment of ...

hematologic malignancies

NCCN Issues New Clinical Practice Guidelines for Myeloproliferative Neoplasms

Myeloproliferative neoplasms are a group of blood cancers characterized by significant symptoms and a high risk of transformation into acute leukemia. These cancers—myelofibrosis, essential thrombocythemia, and polycythemia vera—affect approximately 13,000; 134,000; and 148,000 patients in the...

Nancy E. Davidson, MD, to Lead Fred Hutchinson/University of Washington Cancer Consortium

Fred Hutchinson Cancer Research Center announced that Nancy E. Davidson, MD, Director of the University of Pittsburgh Cancer Institute, has accepted the position of Executive Director of the Fred Hutchinson/University of Washington Cancer Consortium—1 of the 47 National Cancer Institute–designated ...

Yanis Boumber, MD, PhD, Returns to Fox Chase, Department of Thoracic Oncology and Molecular Therapeutics Program

Yanis Boumber, MD, PhD, has joined the Department of Thoracic Medical Oncology and the Molecular Therapeutics Program at Fox Chase Cancer Center. Dr. Boumber first joined Fox Chase’s Department of Medical Oncology in 2013 and now returns to Fox Chase from the University of New Mexico Comprehensive ...

skin cancer

ESMO 2016: Pooled Analysis Shows PD-L1 Expression as a Biomarker for Nivolumab Plus Ipilimumab Response in Advanced Melanoma

A pooled analysis from three clinical trials in advanced melanoma shows that although patients treated with nivolumab and nivolumab plus ipilimumab with ≥ 5% programmed death-ligand 1 (PD-L1) tumor expression have similar progression-free survival, durable response rates were higher for the...

head and neck cancer

ESMO 2016: Meta-analysis Confirms Superiority of Concomitant Over Induction Chemotherapy in Nonmetastatic Head and Neck Cancer

Patients with head and neck squamous cell carcinoma achieved prolonged overall survival when concomitant chemotherapy was administered with locoregional treatment or radiotherapy, according to findings from a large meta-analysis reported by Blanchard et al at the European Society for Medical...

lung cancer

ESMO 2016: Clinical Benefit Demonstrated With Everolimus and Pasireotide LAR Alone or in Combination in Advanced Lung and Thymic Carcinoids

In patients with advanced lung or thymus carcinoid receiving everolimus, pasireotide LAR, or the combination of the two drugs, statistically significant positive impact was seen on proportion of patients’ progression-free rate at 9 months (primary endpoint) in all three arms, more relevant in ...

issues in oncology
cost of care

COA Releases 2016 Community Oncology Practice Impact Report

On October 4, the Community Oncology Alliance (COA) released the 2016 Community Oncology Practice Impact Report, which tracks the changing landscape of cancer care in the United States. It documents a 121% increase in community cancer clinic closings and a 172% increase in consolidation into...

skin cancer

Investigational Immunotherapy Appears Safe and Somewhat Active in Advanced Melanoma

The investigational immunotherapeutic IMC-20D7S was found to be well tolerated and somewhat active in patients with advanced melanoma, including one complete response, according to the results of a phase I/Ib trial reported by Khalil et al in Clinical Cancer Research.  IMD-20D7S is a...

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