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breast cancer
genomics/genetics

Jennifer A. Ligibel, MD, on Gene Expression: Study Findings

Jennifer A. Ligibel, MD, of Harvard Medical School, discusses the impact of preoperative exercise on breast cancer gene expression (Abstract S5-05).

breast cancer

Rowan T. Chlebowski, MD, PhD, on Diet and Breast Cancer: Trial Results

Rowan T. Chlebowski, MD, PhD, of the David Geffen School of Medicine at UCLA, discusses findings from the Women’s Health Initiative Dietary Modification study on low-fat diet and breast cancer overall survival (Abstract S5-04).

survivorship

Integrating AYA Oncology Care Into the Worlds of Pediatric and Adult Oncology Care to Improve Cancer Outcomes

GUEST EDITORAdolescent and Young Adult Oncology explores the unique physical, psychosocial, social, emotional, sexual, and financial challenges adolescents and young adults with cancer face. The column is guest edited by Brandon M. Hayes-Lattin, MD, FACP, Associate Professor of Medicine and...

issues in oncology

Faculty Development in Oncology: Advancing the Field by Optimizing Opportunities for Educators to Learn and Grow

In 2015, Janet Riddle, MD, and her colleagues published an article1 outlining 12 key themes for delineating how fellowship programs in medical education should be developed (See “12 Tips for Developing Successful Fellowship Programs for Medical Educators,” below.) The ASCO Post talked with Dr....

Steven K. Libutti, MD, FACS, Named Director of Rutgers Cancer Institute of New Jersey

Steven K. Libutti, MD, FACS, has been named the new Director of Rutgers Cancer Institute of New Jersey and will serve as Vice Chancellor for Cancer Programs for Rutgers Biomedical and Health Sciences at Rutgers University. When he takes on his new roles in early 2017, Dr. Libutti will be the third ...

global cancer care

Peer-Reviewed Indian Journal of Surgical Oncology Meets Challenges, Succeeds in Developing Country

Launching a new cancer journal is a risky and arduous endeavor, especially for a specialty publication in resource-challenged countries in the developing world. To succeed, a specialty journal must publish articles from established clinical researchers that quickly garner funding and captivate its...

Maura Gillison, MD, PhD, Elected to National Academy of Medicine

Maura Gillison, MD, PhD, a physician-researcher who has made significant contributions to the fields of cancer biology, therapy, and epidemiology, was elected a member of the National Academy of Medicine during the Academy’s annual meeting. Dr. Gillison is the Jeg Coughlin Chair in Cancer...

The Leukemia & Lymphoma Society Invests $40.3 Million in New Research to Find Cures for Hematologic Malignancies

The Leukemia & Lymphoma Society (LLS) has announced it has committed $40.3 million in new research investments to advance the most promising blood cancer science at leading academic and medical centers around the world, including Dana-Farber Cancer Institute; Weill Cornell Medicine; Memorial...

Statement From the American Association for Cancer Research on the House Passage of the 21st Century Cures Act

From Nancy E. Davidson, MD, President of the AACR and Executive Director of the Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium, and Margaret Foti, PhD, MD (hc), Chief Executive Officer of the AACR On behalf of the American Association for Cancer Research (AACR),...

Roy S. Herbst, MD, PhD, Receives 2016 Paul A. Bunn Jr. Scientific Award

Roy S. Herbst, MD, PhD, of Yale University, New Haven, Connecticut, was recognized by the International Association for the Study of Lung Cancer (IASLC) with a distinguished award at the 17th World Conference on Lung Cancer in Vienna, Austria. Dr. Herbst accepted the Paul A. Bunn Jr. Scientific...

AAAS Names Winship’s Dong Moon Shin, MD, as a 2016 Fellow

Dong Moon Shin, MD, the Frances Kelly Blomeyer Distinguished Endowed Chair in Cancer Research at Winship Cancer Institute of Emory University, has been named a Fellow of the American Association for the Advancement of Science (AAAS). Dr. Shin is Professor of Hematology and Medical Oncology,...

breast cancer

Mylin A. Torres, MD, to Hold Glenn Family Chair in Breast Cancer Research at Winship Cancer Institute

Mylin A. Torres, MD, Director of the Glenn Family Breast Center at Winship Cancer Institute of Emory University (Winship), was selected to hold the Louisa and Rand Glenn Family Chair in Breast Cancer Research. The endowed position was created by the Wilbur and Hilda Glenn Family Foundation to...

Tell Your Patients About ASCO’S Award-Winning Cancer.Net Mobile App

Put trusted, oncologist-approved cancer information in the hands of your patients and their caregivers with Cancer.Net Mobile. This award-winning app helps patients plan and manage their cancer care. The newest version of Cancer.Net Mobile is optimized for the latest iOS versions and offers an...

William Sellers, MD, Appointed to Faculty at Broad Institute, Dana-Farber Cancer Institute, and Harvard Medical School

William Sellers, MD, a widely respected cancer researcher with extensive experience in cancer genomics and therapeutic discovery, is returning to the Broad Institute of the Massachusetts Institute of Technology (MIT) and Harvard, Dana-Farber Cancer Institute, and Harvard Medical School (HMS) as a...

issues in oncology

Friends of Cancer Research Rethinks Traditional Clinical Trials

Ellen V. Sigal, PhD, Chair and Founder of Friends of Cancer Research (Friends) began the annual meeting with a conversation with Douglas R. Lowy, MD, National Cancer Institute (NCI) Acting Director, and Robert M. Califf, MD, U.S. Food and Drug Administration (FDA) Commissioner. “Cancer research is ...

ASCO Releases Criteria for High-Quality Clinical Pathways in Oncology

ASCO recently released its Criteria for High-Quality Clinical Pathways in Oncology, a set of 15 interrelated criteria that provide an overarching framework for assessing pathway programs in the United States. ASCO developed the criteria to guide stakeholders in assessing the quality, utility, and...

UNC Lineberger’s Michael R. Kosorok, PhD, Elected AAAS Fellow

University of North Carolina (UNC) Lineberger Comprehensive Cancer Center member Michael R. Kosorok, PhD, has been named a fellow of the American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the journal Science. Dr. Kosorok, who ...

Complete the Free PQRS Reporting Available Through QOPI® by December 31 to Avoid a 2% Medicare Reimbursement Cut in 2018

In September 2016, ASCO announced its latest offering to oncology practices: the ability to complete all Physician Quality Reporting System (PQRS) requirements through the user-friendly Quality Oncology Practice Initiative (QOPI®) platform at no cost. By completing the PQRS module by December 31,...

Team-Based Cancer Care Explored in Special Series of Journal of Oncology Practice

The Journal of Oncology Practice (JOP) published a special series in its November issue representing the results of a unique project launched in 2014 by ASCO and the National Cancer Institute (NCI) to heighten awareness of ways to enhance team-based care in oncology. Concerns about clinician...

ASCO’s TAPUR Study Now Has More Than 100 Participants Receiving Treatment Drugs and 25 New Clinical Trial Sites

More than 100 participants are now enrolled on study drug in ASCO’s Targeted Agent and Profiling Utilization Registry (TAPUR) Study. The trial launched in March 2016 at 37 sites, and in November, it welcomed its newest participating clinical sites: Cancer Treatment Centers of America®,...

Double Your Impact During the Conquer Cancer Foundation Matching Gift Challenge

We have an incredible opportunity for you to make an amazing impact at the Conquer Cancer Foundation! An anonymous donor is offering a Matching Gift Challenge, which will double the value of every gift we receive by December 31—dollar for dollar—up to $64,000! This amount is enough to fund one of...

breast cancer

Diana M. Eccles, MD, on Young Breast Cancer Patients: Results From the POSH Study

Diana M. Eccles, MD, of the University of Southampton, discusses findings from a study of sporadic and hereditary breast cancer and whether BRCA status affects outcome in young breast cancer patients (Abstract S2-03).

Conquer Cancer Foundation Researcher Spotlight: Dr. Priscilla Brastianos

Priscilla Brastianos, MDDirector, Central Nervous System Metastasis ProgramMassachusetts General Hospital Cancer Center, Harvard Medical School, BostonMetastatic brain cancer People are inspired to pursue careers in cancer research for any number of reasons: They might like the challenging nature...

breast cancer

Sonja Vliek, MD, and Sabine Linn, MD, PhD, on Early Breast Cancer: Results of the TEAM IIb Trial

Sabine Linn, MD, PhD, and Sonja Vliek, MD, both of the Netherlands Cancer Institute, discuss study findings on adjuvant ibandronate in postmenopausal women with early breast cancer (Abstract S6-02).

kidney cancer

A Decade of Impact: Conquer Cancer Foundation/Kidney Cancer Association Young Investigator Awards

   The Kidney Cancer Association has supported 12 kidney cancer research projects through the Conquer Cancer Foundation of ASCO Young Investigator Award (YIA) program over the past decade. Early seed funding from the Kidney Cancer Association is advancing research, improving the lives of ...

Christine Laronga, MD, FACS, Elected President of the Association of Women Surgeons

Christine Laronga, MD, FACS, a surgical oncologist specializing in breast cancer at Moffitt Cancer Center, has been named President of the Association of Women Surgeons. The international organization has more than 1,800 members and represents 21 countries. “I am thrilled to be in this new...

hematologic malignancies

ASH Launches Digital, Open-Access Journal Blood Advances at 2016 Annual Meeting

Blood has covered experimental and clinical hematologic research as the flagship journal of the American Society of Hematology (ASH). Launched officially on November 29, 2016, the open-access online journal Blood Advances will fill a niche that complements and expands on topics covered in Blood...

University of Hawaii Cancer Center Receives $3 Million R01 NCI Grant for Bladder Cancer Research

Charles Rosser, MD, MBA, FACS, Professor and Director of the Clinical Trials Office and Director of the Clinical and Translational Research Program at the University of Hawaii Cancer Center, received a 5-year National Cancer Institute (NCI) R01 grant worth more than $3 million. The grant is for...

Make Funding for Cancer Research a Global Priority, Say European and American Organizations

The European Organisation for Research and Treatment of Cancer (EORTC) and the American Association for Cancer Research (AACR) are calling on policymakers and leaders throughout the world to provide robust and sustained funding for cancer research. The two organizations say there has been a...

ASH Honors Member of Congress and Former NCI Grants Chief With Service Awards

The American Society of Hematology (ASH) recognized Representative David McKinley (R-WV) and Roy Wu, PhD, former Chief of the Clinical Grants and Contracts Branch for the Cancer Therapy Evaluation Program at the National Cancer Institute (NCI), with awards for their outstanding advocacy for...

breast cancer

Treatment of Early HER2-Positive Breast Cancer: One Size Does Not Fit All

Despite the routine use of HER2 blockade in early HER2-positive breast cancer, clinicians can always benefit from a refresher on key treatment considerations. Clinical pearls and controversial issues were the topic of a presentation at the 14th Annual School of Breast Oncology at Emory University, ...

Reagan-Udall Foundation Announces Appointments of Ellen V. Sigal, PhD, and Richard L. Schilsky, MD

The Reagan-Udall Foundation for the U.S. Food and Drug Administration (FDA), an independent nonprofit organization that works to advance regulatory science to help support the scientific mission of the FDA, has elected Ellen V. Sigal, PhD, as its new Chairman, and Richard L. Schilsky, MD, as Vice ...

issues in oncology

The FDA Ensures Quality and Safety of Generic Drugs in the United States

The U.S. Food and Drug Administration’s (FDA) generic drug program has substantially increased the availability of affordable, high-quality drugs in the United States. It is arguably the only really effective health-care cost–containment program. The more than 10,000 generic drugs currently...

David Tuveson, MD, PhD, Named Director of the Cold Spring Harbor Laboratory Cancer Center

David Tuveson, MD, PhD, will succeed Bruce Stillman, AO, FAA, FRS, as Director of the Cold Spring Harbor Laboratory Cancer Center. Dr. Tuveson is the Roy J. Zuckerberg Professor of Cancer Research at Cold Spring Harbor Laboratory, the Head of the Lustgarten Foundation Pancreatic Cancer Research...

NCCN Imaging Appropriate Use Criteria Published for 15 Additional Guidelines

The National Comprehensive Cancer Network® (NCCN®), a Centers for Medicare & Medicaid Services (CMS)-approved provider-led entity for imaging appropriate use criteria, continues to build its library of these standards and has published NCCN Imaging Appropriate Use Criteria™ for an additional 15 ...

solid tumors
breast cancer

Fergus J. Couch, PhD, and Max S. Wicha, MD, Recognized for Significant Contributions to Breast Cancer Research at 2016 SABCS

The American Association for Cancer Research (AACR) honored two renowned researchers for their work in breast cancer at the 2016 San Antonio Breast Cancer Symposium (SABCS), held December 6–10 in San Antonio, Texas. Fergus J. Couch, PhD, of the Mayo Clinic, will receive the 9th Annual AACR...

supportive care

Reducing the Risk of Oral Complications During and After Cancer Therapy

According to the National Institutes of Health,1 nearly all patients with head and neck malignancies receiving high-dose radiation therapy; approximately 80% of patients undergoing stem cell transplantation; and about 40% of patients receiving chemotherapy will experience oral complications that...

breast cancer

SABCS 2016: Extended Letrozole Therapy Showed Limited Benefit in Postmenopausal Women With Early-Stage, Hormone Receptor–Positive Breast Cancer

Five additional years of hormone therapy with letrozole following an initial 5 years of aromatase inhibitor-based adjuvant hormone therapy did not demonstrate a statistical improvement in disease-free survival or overall survival in postmenopausal women with early-stage hormone...

breast cancer

SABCS 2016: Adding Everolimus to Fulvestrant Improved Outcomes for Postmenopausal Patients With Hormone Receptor–Positive Breast Cancer

Progression-free survival was more than doubled for patients with metastatic hormone receptor–positive, HER2-negative breast cancer resistant to aromatase inhibitor therapy by adding everolimus (Afinitor) to treatment with the endocrine therapeutic fulvestrant (Faslodex), according to data...

breast cancer

SABCS 2016: Genomic Sequencing of Treatment-Resistant Metastatic Breast Cancer Reveals Clinically Relevant Genetic Alterations

Genomic sequencing of estrogen receptor–positive metastatic breast cancer that had become resistant to therapies revealed multiple genomic and molecular alterations that were not present in the primary tumor samples, with implications for choice of next therapy, clinical trial eligibility,...

health-care policy

ASCO Praises Congress for Accelerating the Development and Delivery of Cancer Treatment With 21st Century Cures Act

In a statement released December 7, ASCO President Daniel F. Hayes, MD, FACP, FASCO, said, “ASCO applauds the U.S. Senate for their decisive vote today to pass the 21st Century Cures Act and authorize funding for the Beau Biden Cancer Moonshot and National Institutes of Health Innovation ...

City of Hope’s Ravi Salgia, MD, PhD, Receives 2016 Asclepius Award From the Bonnie J. Addario Lung Cancer Foundation

City of Hope’s Ravi Salgia, MD, PhD, Chair of the Department of Medical Oncology and Therapeutics Research, has received an accolade that recognizes his decades-long dedication to treating patients with lung cancer and researching new therapies. Dr. Salgia received the 2016 Asclepius Award from...

Cancer Metastasis International Symposium Abstract Award Winners Announced

The Organizing Committee for the 7th International Cancer Metastasis International Symposium has announced the abstract award winners for the meeting. The winners will be presented during the upcoming meeting, “Cancer Metastasis Through the Lymphovascular System: Biology and Treatment,” to be held...

Randi Kaplan, LMSW, Named Schwartz Center’s 2016 National Compassionate Caregiver of the Year

The Schwartz Center for Compassionate Healthcare, a national leader in providing compassionate care to patients and caregivers, has named Randi Kaplan, LMSW, Director of the Arthur D. Emil Caregiver Support Center at Montefiore, the National Compassionate Caregiver of the Year. The prestigious...

Center for Leukemia and Lymphoma Research at UNMC Renamed Dr. James O. Armitage Center for Leukemia and Lymphoma Research

The University of Nebraska Board of Regents voted to rename an area of the University of Nebraska Medical Center (UNMC) in honor of a longtime professor who has made extraordinary contributions to the institution. The Center for Leukemia and Lymphoma Research, established in 2003, was renamed by...

Johns Hopkins Kimmel Cancer Center Expands Cancer Care and Research Facility at Sibley Memorial Hospital in Washington, DC

Cancer experts from the Johns Hopkins Kimmel Cancer Center are now embedded in a newly expanded facility within Johns Hopkins Medicine–owned Sibley Memorial Hospital in northwest Washington, DC. Sibley recently opened the 30,000-square-foot medical oncology facility—part of its new...

lung cancer

New Treatments for Lung Cancer in 2016

With drug approvals for immunotherapy in the first- and second-line settings, breakthroughs in targeting epidermal growth factor receptor (EGFR) mutations, and the rapid evolution of therapies that target anaplastic lymphoma kinase (ALK) rearrangements, 2016 has been an extraordinary year for lung...

issues in oncology

NCI Study Affirms There Is No Safe Level of Smoking

People who consistently smoked an average of less than 1 cigarette per day over their lifetime had a 64% higher risk of earlier death than never-smokers, and those who smoked between 1 and 10 cigarettes a day had an 87% higher risk of earlier death than never-smokers, according to a new study from...

cns cancers

Expert Point of View: Steven Piantadosi, MD, PhD

In an interview with The ASCO Post, Steven Piantadosi, MD, PhD, Professor of Medicine and Director of the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai in Los Angeles, expressed enthusiasm for the Oncology Research Information Exchange Network (ORIEN) network of data-sharing. “With...

gastrointestinal cancer

Liquid Biopsies Identify Molecular Alterations Driving Drug Resistance in Nearly 80% of Patients With Gastrointestinal Cancers

Liquid biopsy technologies are increasingly being used to detect genetic mutations in tumors, giving clinicians the opportunity to see in real time how a patient’s cancer may or may not be responding to treatment. In a study presented recently at the 28th EORTC-NCI-AACR Symposium on Molecular...

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