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Ariel Hollinshead Hyun, PhD, a Pioneer in Cancer Vaccines, Dies at Age 90

Inspiration comes in many forms. For cancer researcher Ariel Hollinshead Hyun, PhD, known professionally as Dr. Hollinshead, it came at the age of 15, when she was captivated by Paul de Kruif’s book Microbe Hunters. She was fascinated by the lives of early bacteriologists detailed in the book and...

lupron

Cancer Taught Me What It Means to Be a Man

Let’s face it, men don’t go to the doctor as often as we should. At least that has been my experience. I felt compelled to finally make an appointment with my primary care physician after I began working as a research assistant at the Smidt Heart Institute at Cedars-Sinai in 2014, as it felt...

issues in oncology

Survey Identifies Gap in Culturally Competent Cancer Care for LGBTQI+ Latinx Population

Most Latinx people who are LGBTQI+ (lesbian, gay, bisexual, transgender, queer, and intersex) reported being reluctant to share their gender identity and/or sexual orientation with a health-care provider, and a majority have never received cancer information tailored for their community, according...

Vassiliki Papadimitrakopoulou, MD, Appointed Clinical Development Leader of Pfizer Oncology

Vassiliki Papadimitrakopoulou, MD, has been appointed Clinical Development Leader of Pfizer Oncology. Dr. Papadimitrakopoulou will be based in New York City. Recognized around the world for her expertise in personalized genomics-driven cancer therapies, immunotherapies, translational research, and ...

Shining Her Light: 2019 International Women Who Conquer Cancer Mentorship Award Recipient Verna Vanderpuye, MBChB

By simply reaching out to new colleagues, Verna Vanderpuye, MBChB, improved the way oncology is practiced across Africa. “It is difficult to find yourself in the [predicament] of low government support, lack of research culture, and inadequate infrastructure,” explained Dr. Vanderpuye, a senior...

yescarta
imlygic
kymriah

Gene Therapy: A March Forward!

GUEST EDITORS Dr. Abutalib is Associate Director, Hematology and Cellular Therapy Program and Director, Clinical Apheresis Program Cancer Treatment at Centers of America, Zion, Illinois; Associate Professor, Rosalind Franklin University of Medicine and Science; and Founder and Co-Editor of...

Lisa M. DeAngelis, MD, Named Physician-in-Chief and Chief Medical Officer of Memorial Sloan Kettering

The Memorial Sloan Kettering (MSK) Cancer Center recently announced that Lisa M. DeAngelis, MD, has been named Physician-in-Chief and Chief Medical Officer. An expert in brain cancer, Dr. DeAngelis previously served as Chair of the Department of Neurology and was Co-Founder of MSK’s Brain Tumor...

Reflecting on My First National Presentation

I gave my first national presentation of my original clinical research on a topic that was to become a professional obsession: finding a cure for esophageal cancer. (Spoiler, I failed.) It was late May 1982. Writing about this now is undoubtedly predicated on my recent retirement, my desire to...

issues in oncology
palliative care

Is Implicit Bias Contributing to Time Disparities in Goals-of-Care Conversations With Minority Patients?

GUEST EDITOR Addressing the evolving needs of cancer survivors at various stages of their illness and care, Palliative Care in Oncology is guest edited by Jamie H. Von Roenn, MD, FASCO. Dr. Von Roenn is ASCO’s Vice President of Education, Science, and Professional Development. It has been well...

supportive care

How to Help Terminally Ill Patients Find Peace in the Dying Process

End-of-Life Oncology is a new occasional column in The ASCO Post that will explore how to ensure the care received by terminally ill patients is in alignment with their end-of-life goals and wishes. In this inaugural installment, The ASCO Post talked with Lillie D. Shockney, RN, BS, MAS,...

issues in oncology
geriatric oncology

Older Sexual and Gender Minorities With Cancer: A Population Hidden in the Open

The term “sexual and gender minorities” encompasses people whose sexual orientation, gender identity and expression, or reproductive development varies from traditional, societal, cultural, or physiologic norms1 and includes lesbian, gay, bisexual, transgender, and queer (LGBTQ) people. More than 3 ...

palliative care
issues in oncology

Is Implicit Bias Contributing to Time Disparities in Goals-of-Care Conversations With Minority Patients?

GUEST EDITOR Addressing the evolving needs of cancer survivors at various stages of their illness and care, Palliative Care in Oncology is guest edited by Jamie H. Von Roenn, MD, FASCO. Dr. Von Roenn is ASCO’s Vice President of Education, Science, and Professional Development. It has been well...

head and neck cancer

HPV-Positive Oropharyngeal Cancer Burden Rising Among White Men in the United States

White men older than age 65 will have the greatest burden of oropharyngeal cancer by the year 2030, according to Maura L. Gillison, MD, PhD, Professor and Endowed Chair at MD Anderson Cancer Center in Houston. But there is some good news, she said at the 2019 Winship Cancer Institute of Emory...

ASCO Commentary in the Journal of Geriatric Oncology Reflects on the Legacy of Arti Hurria, MD, FASCO

A new ASCO paper in the Journal of Geriatric Oncology1 fondly reflects on the impact of Arti Hurria, MD, FASCO, in improving the treatment of older adults with cancer. The article is part of a special issue honoring her work in this area. Dr. Hurria was killed in a traffic accident on November 7,...

International Innovation Grants Expand Global Reach of Training and Care

Physicians and nurses in low- and middle-income countries (LMICs) have fewer training opportunities, limited medical and educational resources, and insufficient palliative care options for their patients,1 all while these regions are leading the world in new cases of cancer diagnosis.2 An emerging...

Denise R. Aberle, MD, Honored by IASLC for Contributions to the Prevention of Lung Cancers

Denise R. Aberle, MD, of the David Geffen School of Medicine at the University of California at Los Angeles (UCLA), was recognized by the International Association for the Study of Lung Cancer (IASLC) with the Joseph W. Cullen Prevention/Early Detection Award at the IASLC 2019 World Conference on...

bladder cancer
issues in oncology

The Fight Against Breast Cancer Illustrates the Health-Care Challenges of Women in Poverty

"Of all the forms of inequality, injustice in health is the most shocking and the most inhumane….” —Dr. Martin Luther King, Jr Progress has been made in expanding access to health care for low-income populations, but the quality of care still lags behind and can result in less successful outcomes...

Special Events at the 2019 ASCO Annual Meeting

1. (Left to right) Sandra Swain, MD, FASCO, Lynn M. Schuchter, MD, FASCO, and Linda Bosserman, MD, FACP, FASCO, among the speakers and guests at the Women Leaders in Oncology Event, held in conjunction with the ASCO Annual Meeting, June 3, 2019. Photo by © ASCO/Matt Herp 2019. 2. Attendees at the...

Personalizing Medicine

The ASCO Post is pleased to reproduce installments of the Art of Oncology as published previously in the Journal of Clinical Oncology. These articles focus on the experience of suffering from cancer or of caring for people diagnosed with cancer, and they include narratives, topical essays,...

ESMO 2019 Award Winners Announced

The European Society for Medical Oncology (ESMO) has revealed the 2019 winners of its annual awards. The four distinguished clinicians and scientists will be presented during the ESMO 2019 Congress in Barcelona: Eric Van Cutsem, MD, PhD; Angelo Di Leo, MD, PhD; Cristiana Sessa, MD; and Charles...

prostate cancer

Two Fred Hutch Scientists Receive Fellowships for Prostate Cancer Research

Two early-career scientists at Fred Hutchinson Cancer Research Center—Alexandra Corella and Sander Frank, PhD—have received grants to further their prostate cancer research. Ms. Corella, a graduate research assistant, won a $25,000, 1-year fellowship from the Ford Foundation Fellowship Programs,...

kadcycla
herceptin

Adjuvant Treatment With Ado-trastuzumab Emtansine in HER2-Positive Early Breast Cancer

In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms of action, administration recommendations, safety profiles, and other essential information needed for the appropriate clinical use of these drugs. Earlier this year, ado-trastuzumab emtansine (T-DM1) was...

supportive care

Chef Uses Flavor to Fuel Her Mother’s Appetite During Cancer Treatment

The battle against cancer is typically waged by the surgeon and oncologist, but a Lexington, Kentucky–based, award-winning restaurateur and chef discovered her role as a foot soldier when she applied her culinary skills to deal with the debilitating side effects of her mother’s lung cancer...

issues in oncology

Lauren M. Hamel, PhD, on Race and Doctor-Patient Behavior

Lauren M. Hamel, PhD, of Wayne State University/Karmanos Cancer Institute, discusses her findings on the ways in which nonverbal behavior between doctors and patients of the same or different races can affect their relationship, quality of communication, and ultimately, perhaps outcomes as well...

issues in oncology

Mallika Sharma, MPH, on Eliminating Prior Authorizations, Anxiety, Delay in Care, Higher Costs

Mallika Sharma, MPH, of Seattle Cancer Care Alliance, discusses her findings that, by doing away with the many prior authorization denials based on administrative errors, providers may offer higher-value care by eliminating unnecessary anxiety among patients, administrative burdens, and increased...

issues in oncology

Grace C. Hillyer, EdD, MPH, on Enrolling Patients in Clinical Trials: Improving Clinician-Patient Communication

Grace C. Hillyer, EdD, MPH, of Columbia University Mailman School of Public Health, discusses the many barriers to enrolling patients in clinical trials, most notably different attitudes toward and perceptions about research studies among clinicians vs patients. Her findings point to the need for...

lung cancer

Cristina Merkhofer, MD, MHS, on NSCLC: Survival Impact of Taking Part in a Clinical Trial

Cristina Merkhofer, MD, MHS, of Fred Hutchinson Cancer Research Center, discusses study results showing that for patients with metastatic non–small cell lung cancer at her institution, enrolling in a therapeutic drug clinical trial was associated with a 47% lower risk of death, compared with not...

A Vigorous Life Through the Prism of Impending Death

“Live while you’re living, friends,” writes Julie Yip-­Williams in her memoir, The Unwinding of the Miracle: A Memoir of Life, Death, and Everything That Comes After. It was The New York Times bestseller when she died of stage IV colon cancer at the age of 42. She is the most recent of several...

Not for the Squeamish: Surgery in the 19th Century

Imagine undergoing major surgery in a grimy operating room without any form of antisepsis. That was the grim reality in the 1800s, when the ruling theory was that damage from “bad air” was responsible for infections in surgical wounds. Hospitals simply aired out the surgical wards at midday to...

Doctor, Where Art Thou?

The ASCO Post is pleased to reproduce installments of the Art of Oncology as published previously in the Journal of Clinical Oncology. These articles focus on the experience of suffering from cancer or of caring for people diagnosed with cancer, and they include narratives, topical essays,...

Nakul Singhal, MD, and Nicole Carreau, MD, Join New York Cancer & Blood Specialists

Oncologist Nakul Singhal, MD, has joined New York Cancer & Blood Specialists (NYCBS) and will be accepting new patients at the Bayside and New Hyde Park locations. NYCBS also welcomes oncologist Nicole Carreau, MD. Prior to joining NYCBS, Dr. Singhal practiced at Hackensack Meridian Health...

breast cancer

Insightful Advice From a College Advisor Leads to an Unexpected Career in Oncology

For this installment of the Living a Full Life series, guest editor Jame Abraham, MD, FACP, spoke with Tatiana M. Prowell, MD, who currently serves as Associate Professor of Oncology in the Breast Cancer Program at the Johns Hopkins Kimmel Comprehensive Cancer Center and as a Medical Officer and...

issues in oncology

Confronting the Criticisms Facing Watson for Oncology

Over the past 2 years, IBM’s Watson for Oncology cognitive computing system, which uses artificial intelligence (AI) algorithms to generate treatment recommendations, has come under fire for allegedly not delivering on expectations to provide state-of-the-art personalized treatment for patients...

issues in oncology

Firing Your Patient: How to Terminate a Treatment Relationship

Many clinicians are confused by the evolving opioid prescribing guideline issued by the Centers for Disease Control and Prevention (CDC) meant to stem the rising epidemic of opioid addiction and overdose in the United States.1 Many are also worried about regulatory oversight by the U.S. Drug...

pancreatic cancer

Sita Kugel, PhD, Receives Grant to Study Aggressive Type of Pancreatic Cancer

The deadly nature of most pancreatic tumors is well known, with less than 10% of patients with pancreatic ductal adenocarcinoma estimated to survive 5 years after diagnosis. Recent molecular analyses of pancreatic ductal adenocarcinoma have shown that a patient’s prognosis changes depending on the...

issues in oncology

Hey Siri, Should I Get a Medical Degree?

I received a coffee mug from a physician colleague some years ago with the tag line: “Please do not confuse your Google search with my Medical Degree.” Physicians of all stripes and colors can relate to the agony of debunking a “Dr. Google” diagnosis. However, in a fast-evolving health-care...

issues in oncology

How Patient Advocacy Is Integral to High-Quality Oncology Care

Karen M. Winkfield, MD, PhD, has made patient advocacy—with a specific emphasis on health equity and access to high-quality care—front and center of her oncology practice since she completed her residency at the Harvard Radiation Oncology Program in Boston, where she noticed that most of the...

head and neck cancer

Maura L. Gillison, MD, PhD, Pioneer in HPV-Related Head and Neck Cancer, Has Often Changed Lanes in Her Career

When The ASCO Post asked physician-scientist Maura L. Gillison, MD, PhD, where she was from, she answered, “North America.” Actually, she was born in Canada, but her father worked for a large international company, so the family moved regularly through Canada, the United States, and Mexico. “I...

Your Stories: How to Become a Conqueror

NOT ALL PATIENTS face their cancer diagnosis with a conqueror’s sprit. In the podcast “How to Become a Conqueror,” Linda Zanetti shares how a community of support gave her the resources—and the will—to survive leukemia. Developed by Conquer Cancer®, the ASCO Foundation, the Your Stories podcast...

lung cancer
immunotherapy

Optimal First-Line Therapy for Stage IV Non–Small Cell Lung Cancer: Immunotherapy Alone or With Chemotherapy?

Recent studies in non–small cell lung cancer (NSCLC) have shown benefit for combining checkpoint inhibitors with chemotherapy. Should combinations, therefore, be the first choice for treating patients with newly diagnosed stage IV disease? Two lung cancer experts debated this point at the 2019...

ASTRO Elects Four New Officers to Board of Directors

The members of the American Society for Radiation Oncology (ASTRO) have elected four new officers to ASTRO’s Board of Directors. Laura Dawson, MD, FASTRO, will begin her term as President-Elect in September during ASTRO’s 61st Annual Meeting in Chicago. Neha Vapiwala, MD, was elected as ASTRO’s new ...

V. Craig Jordan, CMG, OBE, PhD, DSc, Honored for Accomplishments in Women’s Health

The Companion of the Most Distinguished order of St. Michael and St. George (CMG) is generally reserved for ambassadors and leaders of the United Kingdom’s defense and security services. Only 1, 750 appointees are permitted. This year, the Head of M16, the Secret Intelligence Service, was in the...

West Virginia University Cancer Institute Welcomes Eight New Doctors

The West Virginia University (WVU) Cancer Institute continues to expand its list of specialists with the addition of eight new doctors. Sonikpreet Aulakh, MD, will join WVU Medicine from Mayo Clinic Florida, where she is completing a hematology oncology fellowship. She completed her medical degree...

pancreatic cancer

Germline RABL3 Mutation May Increase Risk of Pancreatic Cancer Development

Scientists who studied a highly cancer-prone single family have identified a rare, inherited gene mutation that may raise the lifetime risk of pancreatic and other cancers. Their findings were published by Nissim et al in Nature Genetics. The discovery of the previously unknown mutation could lead ...

The Opioid Overdose Crisis: Victims, Villains, and the Gray Area in Between

According to politicians and the media, such as award-winning journalist Beth Macy, we are in the midst of the worst drug crisis in American history. Sparked first by oxycodone and broadening into heroin and fentanyl, opioid addiction is indeed ravaging communities across the nation, largely in...

integrative oncology

Echinacea

The ASCO Post’s Integrative Oncology series is intended to facilitate the availability of evidence-based information on integrative and complementary therapies sometimes used by patients with cancer. In this installment, Yen Nien Hou, PharmD, DipIOM, LAc, explores the potential health benefits of...

Out of the Mouths of Babes: A Physician Discusses Her Cancer Diagnosis With Her Two Young Children

  In medical school, I learned a five-step model on how to deliver bad news to a patient. I still fall back on this method, time and again, in my primary care clinic; I have even used it when giving really tough feedback to a learner who is struggling in some aspect of performance. But I honestly...

issues in oncology
genomics/genetics

How Technology Is Transforming the Assessment of Inherited Cancer Risk

ASCO published its first statement on genetic testing and its impact on oncology practice over 2 decades ago. Since then, ASCO has revised the statement three times, the most recent in 2015, in response to advances propelled by the sequencing and mapping of the human genome and the identification...

issues in oncology
health-care policy

Looking at the Impact of State Policies on Access to High-Quality Care

The state of Washington is adding a public option to its health insurance marketplace; Massachusetts, Connecticut, and others have passed laws requiring that payers cover fertility preservation procedures for patients with cancer. Many states are seeking to expand Medicaid eligibility, and some, in ...

breast cancer
genomics/genetics

How Laura J. van ’t Veer, PhD, Became an Expert in Genetic Testing for Breast Cancer

Breast cancer researcher and innovator Laura J. van ’t Veer, PhD, was born and reared in Amsterdam in 1957. “During high school, I had a wonderful biology teacher who was going through his own biology studies at the University of Amsterdam, and he was bringing that university-level education into...

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