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issues in oncology

Keeping Staff and Patients Safe From Workplace Violence

The statistics are chilling. According to estimates from the U.S. Bureau of Labor Statistics, workers in the fields of health care and social services are five times more likely to suffer from a workplace violence injury than workers overall.1 The Bureau statistics show that the rate of injuries...

issues in oncology

‘I Want to Kill You’

My patient threatened to kill me. I was in the middle of a busy medical oncology clinic. I was seeing her to discuss test results 1 week after I told her I was concerned that her cancer had returned. As I suspected, the test confirmed recurrent cancer, and this time, it was incurable. I walked into ...

lymphoma

Third-Line Treatment for Relapsed/Refractory Diffuse Large B-Cell Lymphoma

This is Part 3 of Clinical Advances in Diffuse Large B-Cell Lymphoma, a three-part video roundtable series. Scroll down to watch the other videos from this Roundtable.   In this video, Drs. Jeremy Abramson, Laurie Sehn, and Kieron Dunleavy discuss the third-line treatment of relapsed/refractory...

lymphoma

Second-Line Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

This is Part 2 of Clinical Advances in Diffuse Large B-Cell Lymphoma, a three-part video roundtable series. Scroll down to watch the other videos from this Roundtable.   In this video, Drs. Jeremy Abramson, Laurie Sehn, and Kieron Dunleavy discuss the second-line treatment of relapsed/refractory...

lymphoma

Newly Diagnosed High-Risk Diffuse Large B-Cell Lymphoma

This is Part 1 of Clinical Advances in Diffuse Large B-Cell Lymphoma, a three-part video roundtable series. Scroll down to watch the other videos from this Roundtable.   In this video, Drs. Jeremy Abramson, Laurie Sehn, and Kieron Dunleavy discuss the treatment of newly diagnosed high-risk diffuse...

gynecologic cancers
supportive care
symptom management

Psilocybin and Other Psychedelics May Help Patients With Late-Stage Gynecologic Cancer Tackle Mental Health Symptoms

Investigators revealed that psilocybin-assisted psychotherapy and other psychedelics may effectively ease symptoms of anxiety and depression in patients with late-stage gynecologic cancers, according to a new commentary published by Yaniv et al in the International Journal of Gynecological Cancer.  ...

head and neck cancer

Expert Point of View: Priyanka Bhateja, MD

Head and neck cancer specialist Priyanka Bhateja, MD, Assistant Professor in the Division of Medical Oncology, The Ohio State University Comprehensive Cancer Center, was encouraged by the findings of the Quarterback trial. As she noted in her comments for The ASCO Post, human papillomavirus...

Damon Runyon Names Physician-Scientist Awardees

Three scientists who are researching novel approaches to the treatment of cancer have been named the 2023 recipients of the Damon Runyon Physician-Scientist Training Award: Nicole M. Cruz, MD; Mounica Vallurupalli, MD; and Nina Weichert-Leahey, MD. The awardees were selected through a highly...

Allison Institute Announces Appointment of Inaugural Members

The James P. Allison Institute at The University of Texas MD Anderson Cancer Center has announced the appointment of its first members, including pioneering researchers who have made notable contributions to science as well as rising stars on the path toward important breakthroughs. This group will ...

Expert Point of View: Kathleen Moore, MD, MS

“I think the NOW trial is a great study,” said Kathleen Moore, MD, MS, the Virginia Kerley Cade Endowed Chair in Cancer Developmental Therapeutics and Professor of Gynecologic Oncology at the University of Oklahoma Health Sciences Center, Oklahoma City, who shared her thoughts on the trial with The ...

hematologic malignancies

Goals of Care in Primary Myelofibrosis

This is Part 3 of Updates in Myeloproliferative Neoplasms, a three-part video roundtable series.   In this video, Dr. Naveen Pemmaraju and Dr. Gabriela Hobbs discuss goals of care in primary myelofibrosis.   The patient is a 27-year-old woman who presents to the clinic after 6 months of...

breast cancer

I Didn’t Want My Past to Become My Future

When I felt a large mass in my left breast as I was drying off from a shower on Thanksgiving Day, in 2007, I instinctively knew it was cancer. My mother had been diagnosed with breast cancer when she was 38, just 7 years older than I was at the time, and died 4 years later. I was 6 when she was...

breast cancer
supportive care

Targeting Depressive Symptoms in Younger Breast Cancer Survivors

Guest Editor’s Note: Psychological distress is highly prevalent in women diagnosed with premenopausal breast cancer and has a significant negative impact on their quality of life. Thus, effective strategies are urgently needed to reduce the symptom burden. In this installment of The ASCO Post’s...

geriatric oncology
global cancer care

Assessing Geriatric Oncology Practice in Portugal

The global population is aging rapidly. Currently, there are more than 703 million people worldwide aged 65 and older, representing 9.1% of the global population. It is estimated that this percentage will grow to 15.9%—1.5 billion people—by 2050.1 And with that growing aging population will come...

Sara Hurvitz, MD, Joins Fred Hutch, University of Washington, Seattle

On August 1, 2023, Sara Hurvitz, MD, will assume the role of Senior Vice President of the Clinical Research Division at Fred Hutch and as Head of the newly united Division of Hematology and Oncology at the University of Washington Department of Medicine in Seattle. Dr. Hurvitz will report directly...

global cancer care

A European Leader in Surgical Oncology, Isabel T. Rubio, MD, PhD, Shares Her Story and Sheds Light on the Challenges Ahead

In this installment of The ASCO Post’s Global Oncology series, guest editor Chandrakanth Are, MBBS, MBA, FRCS, FACS, spoke with Isabel T. Rubio, MD, PhD, Head of Breast Surgical Oncology at Clinica Universidad de Navarra, Madrid. Dr. Rubio is active in many societies and is a founding member and...

gynecologic cancers
issues in oncology

Fertility in Female Survivors Treated for Hodgkin Lymphoma as Children

Female survivors treated for Hodgkin lymphoma may face declining fertility at a younger age, according to recent findings presented by Drechsel et al at the European Society of Human Reproduction and Embryology (ESHRE) 2023 Annual Meeting (Abstract O-083). The new research also suggested that the...

Ivy Brain Tumor Center Appoints New Chief Medical Officer

Yoshie Umemura, MD, was recently appointed as Chief Medical Officer of the Ivy Brain Tumor Center and Chief of Neuro-Oncology and the William and Joan Shapiro Chair of Neuro-Oncology at Barrow Neurological Institute. Dr. Umemura plans to build on the Ivy Center’s clinical trials program and...

skin cancer
immunotherapy

Expert Point of View: Zeynep Eroglu, MD

The formal discussant of the phase II SWOG S1512 trial was Zeynep Eroglu, MD, of the Department of Cutaneous Oncology at the Moffitt Cancer Center in Tampa, Florida. She congratulated Dr. Kendra and her coauthors for conducting a study in such a rare tumor. “I think we can say desmoplastic melanoma ...

issues in oncology

Thinking Outside the Box: Embracing Innovation and Collaboration in Oncology

In the ever-evolving landscape of oncology care, embracing innovation and creative problem-solving have become crucial factors for success. At the 2023 Community Oncology Alliance Annual Meeting, a panel discussion tackled the complexities and opportunities associated with implementing value-based...

pancreatic cancer

Early Detection of Pancreatic Cancer Saved My Life

When my sister was diagnosed with breast cancer 25 years ago, her medical team suggested we undergo genetic testing for the BRCA gene mutation. I knew that being a BRCA carrier put me at greater risk for breast and ovarian cancers, but I had no idea it also increased my risk for pancreatic cancer....

issues in oncology

Involving All of Society to End Cancer as We Know It

This has been a year of firsts and seconds for Monica M. Bertagnolli, MD, FACS, FASCO. This past October, Dr. Bertagnolli became the 16th Director of the National Cancer Institute (NCI), the first woman and the first clinical trials cooperative group chair to hold that position. Then, 2 months...

lymphoma

Jennifer L. Crombie, MD, on DLBCL: Real-World Outcomes With Novel Therapies in Relapsed or Refractory Disease

Jennifer L. Crombie, MD, of Dana-Farber Cancer Institute, discusses the historically poor outcomes for patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). Her study examined real-world data on the use of novel therapies in this population and found that outcomes with second- ...

Finding Early Female Role Models Helped Shape a Notable Career in Oncology

Elizabeth M. Jaffee, MD, Deputy Director of The Sidney Kimmel Comprehensive Cancer Center, Baltimore, was born in Brooklyn, New York, in a place and time she found exhilarating during her early years. “We didn’t have a lot of money—actually, we were poor. But I had a lot of freedom walking around...

Daughter of Immigrants Who Fled the Pogroms, She Followed a Love of Science Into a Noted Career in Cancer Pathology

In the era of genomics and precision medicine, the role of pathology in diagnosis and cancer management is rapidly evolving. For the past 50 years, from her office at the Center for Cancer Research, National Cancer Institute (NCI), pathologist Elaine S. Jaffe, MD, has been at the forefront of that...

ASCO Congratulates 2023 Special Awards Recipients

ASCO and Conquer Cancer, the ASCO Foundation, will recognize researchers, patient advocates, philanthropists, teachers, and global oncology leaders who have reshaped cancer care with the Society’s highest honors at the 2023 ASCO Annual Meeting in Chicago. Hear from select award recipients at the...

An Oncology Leader Whose Immigrant Parents Taught Him by Example About Life and Service to Humanity

According to Sunil R. Hingorani, MD, PhD, his parents figured heavily on who he became as a person and on his career choices, which ultimately led to his current position as Director of the Pancreatic Cancer Center of Excellence at the University of Nebraska College of Medicine, Omaha. “My father...

Involvement in SWOG and JCO Leads to a Fulfilling Career as a Leader in Oncology

Jonathan W. Friedberg, MD, MMSc, Director of the James P. Wilmot Cancer Institute, grew up in a suburb of Milwaukee. While his school friends were attending camp, he spent his summers working on the family farm. “Perhaps the hardest work I’ve ever done was haying on a hot, humid night in July,...

supportive care
symptom management

Patients Who Practice Qigong May Be Able to Improve Their Cancer-Related Fatigue

Researchers have found that patients with cancer-related fatigue who practiced qigong may have demonstrated clinically significant improvements in their fatigue burden after 10 weeks, according to a new study published by Zimmerman et al in Integrative Cancer Therapies. The findings revealed that...

Mourned and Missed

The respected members of the oncology community listed here are among some of those who passed away in 2022–2023. The ASCO Post remembers them, their lives, and their contributions to cancer research and treatment. Robert J. Gillies, PhD Moffitt Cancer Center and the global research community lost ...

skin cancer

A Love of Immunology Leads to a Notable Career in Dermatology, With a Focus on Melanoma Research and Treatment

Caroline Robert, MD, PhD, Head of the Dermatology Unit at Gustave Roussy and Co-Director of the Melanoma Research Unit at INSERM 981 Paris-Sud University, was born and reared in Paris. “I didn’t have a vocation for medicine when I was a kid; I wanted to be an archeologist. I’m not from a medical...

From a Small Town in North Carolina, a Young Girl Finds Her Calling in Battling Inequity in Cancer Care

Manali Patel, MD, MPH, Associate Professor of Medicine (Oncology) at Stanford University, grew up in Shelby, a small town in the textile and farming community of Western North Carolina, among mill workers and other blue-collar laborers. The daughter of Indian immigrants, Dr. Patel’s early life was...

survivorship

A Free-Spirited Childhood on a Dairy Farm, Where Books and Science Experiments Were Encouraged

Susan K. Parsons, MD, MRP, Professor of Medicine and Pediatrics at Tufts University School of Medicine and Founding Director of the Reid R. Sacco Adolescent and Young Adult Program for Cancer and Hereditary Blood Disorders at Tufts Medical Center, grew up on a working dairy farm in Sharon Springs,...

gastrointestinal cancer
health-care policy

Medicaid Expansion Associated With a Reduction in Mortality for Black Patients With Gastrointestinal Cancers

Studies showed that racial minorities experience disparities in access to cancer treatment and survival. In an effort to improve access to care for disadvantaged populations, the Affordable Care Act provided funding to states to expand Medicaid eligibility criteria and provide coverage to...

ASCO Congratulates 2023 Special Awards Recipients

ASCO and Conquer Cancer, the ASCO Foundation, will recognize researchers, patient advocates, philanthropists, teachers, and global oncology leaders who have reshaped cancer care around the world with the Society’s highest honors at the 2023 ASCO Annual Meeting in Chicago. Hear from select award...

Making the Art of Oncology and Cancer Care Central to Her Presidential Term

Lynn M. Schuchter, MD, FASCO, has said that volunteering and working with ASCO over many years has been the highlight of her career. She served on the ASCO Board of Directors from 2009 to 2012 and on several ASCO committees, including terms as Chair of the Annual Meeting Scientific Program...

Northwell Launches Cancer Care Direct, Pairing Nurse Navigators With Patients Through Spectrum of Care

Knowing the health-care system is complex and often creates anxiety for patients newly diagnosed with cancer, the Northwell Health Cancer Institute has launched Cancer Care Direct, a comprehensive program to connect patients with clinical registered nurse navigators who can provide expert guidance...

survivorship

Surviving, but Not Always Thriving, After Cancer

As discussed in Part I of this special feature on cancer survivorship, there are now more than 18 million cancer survivors in the United States, and that number is expected to grow to 26 million by 2040.1 However, most of those survivors—at least two-thirds—either cured or in remission or living...

survivorship

Surviving, but Not Always Thriving, After Cancer

The improvement in cancer survival rates since President Richard M. Nixon signed the National Cancer Act of 1971 into law is staggering. The legislation further committed the United States to greater investments in cancer-focused research to drive down the rates of cancer diagnoses, boost patient...

breast cancer

Playing a Doctor in a School Play Sparked an Early Desire to Become a Real Doctor for Sibylle Loibl, MD, PhD

For this installment of The ASCO Post’s Living a Full Life series, guest editor Jame Abraham, MD, FACP, spoke with Sibylle Loibl, MD, PhD, Chair of the German Breast Group (GBG) and Chief Executive Officer of the GBG Forschungs GmbH. Professor Loibl, Associate Professor of Obstetrics and Gynecology ...

breast cancer

Surveillance Mammography Rates After Breast Cancer Treatment Remain High, Irrespective of Life Expectancy

Is regular surveillance with mammography important in older patients with breast cancer and a shortened life expectancy? A study of 44,475 patients with breast cancer found the practice—which may yield more harms than benefits—to be common. This study is unique in that it examined surveillance...

gynecologic cancers

Expert Point of View: Carol Aghajanian, MD

Carol Aghajanian, MD, Chief of the Gynecologic Medical Oncology Service at Memorial Sloan Kettering Cancer Center, New York, commented on the final analysis of NOVA for The ASCO Post. She highlighted the difficulty in truly measuring overall survival in recurrent ovarian cancer. Dr. Aghajanian also ...

gynecologic cancers

Expert Point of View: Amanda Nickles Fader, MD

Amanda Nickles Fader, MD, Professor of Gynecology and Obstetrics, Professor of Oncology, and Vice Chair of Gynecologic Surgical Operations at Johns Hopkins Health System, Baltimore, provided her thoughts on GOG 3026 for The ASCO Post. Dr. Fader applauded the investigators and the Gynecologic...

gynecologic cancers

GOG 258 Final Results: No Improvement in Survival by Adding Radiotherapy to Chemotherapy in Advanced Endometrial Cancer

The long-running randomized NRG Oncology GOG-258 clinical trial failed to identify an overall survival benefit with adjuvant chemoradiotherapy vs chemotherapy alone in any subgroup of patients with locally advanced endometrial cancer. After a median follow-up of 112 months, the hazard ratio for...

breast cancer
supportive care

Expert Point of View: Sarah Blair, MD

Sarah Blair, MD, Professor and Vice Chair of the Department of Surgery at UC San Diego Health in California, offered her thoughts on the findings from these two studies. She first pointed to the growing body of data showing how nutrition and exercise programs can improve aerobic fitness, quality of ...

President Biden Announces Intent to Nominate Monica M. Bertagnolli, MD, as Director of the NIH

In a statement released by The White House on May 15, President Joe Biden announced his intent to nominate Monica M. Bertagnolli, MD, as Director of the National Institutes of Health (NIH), the world’s preeminent biomedical research organization. As the statement makes clear, Dr. Bertagnolli is a...

gynecologic cancers

Prognostic Factors Associated With Survival in Platinum-Resistant Ovarian Cancer

Overall survival time was doubled in women with recurrent platinum-resistant ovarian cancer who have BRCA1/2 mutations, who were treated with PARP inhibitors, and whose tumors were homologous repair–deficient (HRD-test–positive), according to a study that examined prognostic factors for survival in ...

gynecologic cancers

Expert Point of View: Carol Aghajanian, MD

Carol Aghajanian, MD, Chief of the Gynecologic Medical Oncology Service at Memorial Sloan Kettering Cancer Center, New York, commented on the final analysis of NOVA for The ASCO Post. She highlighted the difficulty in truly measuring overall survival in recurrent ovarian cancer. Dr. Aghajanian also ...

gynecologic cancers

Expert Point of View: Amanda Nickles Fader, MD

Amanda Nickles Fader, MD, Professor of Gynecology and Obstetrics, Professor of Oncology, and Vice Chair of Gynecologic Surgical Operations at Johns Hopkins Health System, Baltimore, provided her thoughts on GOG 3026 for The ASCO Post. Dr. Fader applauded the investigators and the Gynecologic...

breast cancer

Novel Hormone Receptor–Driven Therapies Tackling Endocrine Resistance in Breast Cancer

In hormone receptor–positive metastatic breast cancer, tumors eventually become resistant not only to endocrine blockade but to inhibitors of cyclin-dependent kinases 4 and 6 (CDK4/6). This obstacle to successful treatment is being tackled with novel hormone receptor–directed therapies, with the...

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