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American Cancer Society Honors William Breitbart, MD, With the Trish Greene Quality of Life Award

William Breitbart, MD, has been honored with the 2017 American Cancer Society Trish Greene Quality of Life Award, a prestigious national honor that recognizes an outstanding individual who dedicates a significant portion of his or her career to research that improves the quality of life for cancer ...

bladder cancer

Roland Seiler, MD, on Bladder Cancer: Subtypes and Treatment Response

Roland Seiler, MD, of the University of British Columbia, discusses a way to identify molecular subtypes of muscle-invasive bladder cancer, the varying responses to cisplatin-based neoadjuvant chemotherapy, and which patients show the most benefit. (Abstract 281)

issues in oncology
survivorship

Many Cancer Survivors Find Online and Telephone Communication With Health-Care Professionals Beneficial

Researchers from the School of Health Sciences at the University of Surrey, Guildford, United Kingdom, have completed the first-ever systematic review of cancer survivors’ experience of online and telephone telehealth interventions in cancer care, according to a recent study reported by Anna Cox,...

lung cancer

New Lung Cancer Staging Manual Set to Modify Clinical Practice

A revised tumor classification based on 70,967 evaluable patients with non–small cell lung cancer (NSCLC) and 6,189 patients with small cell lung cancer is now available to lung cancer specialists around the world in the form of the 8th edition of the tumor, node, and metastasis (TNM)...

Edward Garon, MD, Receives $3.2 Million NIH Grant to Study Immunotherapy Responses in Lung Cancer

Edward Garon, MD, a member of the University of California, Los Angeles (UCLA) Jonsson Comprehensive Cancer Center and Associate Professor of Hematology and Oncology at the David Geffen School of Medicine, has received a 5-year, $3.2 million grant from the National Institutes of Health (NIH) to...

lung cancer

Combination Immunotherapy for Lung Cancer: The Wave of the Future

Increasing experience with immunotherapy for lung cancer in both the lab and the clinic is helping to refine treatment approaches and point the way forward, according to Naiyer Rizvi, MD, Director of both Thoracic Oncology and Immunotherapeutics at Columbia University Medical Center in New York....

lung cancer

Managing Toxicities Associated With Immunotherapy for Lung Cancer

Understanding, anticipating, and managing the toxicities associated with immunotherapies for lung cancer are key to steps to safely using and achieving the most benefit from these new agents, according to Beth Eaby-Sandy, MSN, CRNP, OCN, a nurse practitioner at the University of Pennsylvania’s...

lung cancer

Expert Point of View: Michael Boyer, MBBS, PhD

“The OAK subgroup analyses showed the benefit of atezolizumab (Tecentriq) virtually “across the board,” including among patients with programmed cell death ligand 1 (PD-L1)–negative tumors, remarked invited discussant, Michael Boyer, MBBS, PhD, Chief Clinical Officer and Conjoint Chair of Medical...

lung cancer

Expert Point of View: Edward B. Garon, MD

“There are several possible ways to move first-line immunotherapy for non–small cell lung cancer (NSCLC) forward, according to invited discussant Edward B. Garon, MD, Director of Thoracic Oncology at the David Geffen School of Medicine at the University of California, Los Angeles. “We could expand...

lung cancer

Understanding the Role of Immunotherapy for Lung Cancer: A Paradigm Shift for the Better

“Immunotherapy for lung cancer is a paradigm shift. I would never have thought when I started my career taking care of lung cancer patients in the mid 1990s that we’d now be substituting chemotherapy with an antibody immunotherapy in 2017. It’s incredible,” commented Roy S. Herbst, MD, PhD, Chief...

hematologic malignancies

Early Biomarker Algorithm May Predict Graft-vs-Host Disease Occurrence

Researchers at Mount Sinai Health System have discovered a way to predict whether patients with blood cancer who received a bone marrow transplant will develop graft-vs-host disease, according to a study published by Hartwell et al in JCI (The Journal of Clinical...

kidney cancer

2017 GU Cancers Symposium: In Advanced Kidney Cancer, Antibiotic Use Lowers Efficacy of Immunotherapy

A new retrospective analysis suggests that immunotherapy may be less effective in patients who receive antibiotics less than a month before starting treatment. In the study, cancer worsened more quickly in such patients than in those who did not receive antibiotics (with median progression-free...

multiple myeloma

Does Obesity Pose Risk for Transformation of Monoclonal Gammopathy of Undetermined Significance to Myeloma?

In a population-based cohort study reported in the Journal of the National Cancer Institute, Chang et al found that overweight and obesity were associated with an increased risk of transformation of monoclonal gammopathy of undetermined significance to multiple myeloma. Black race was also...

survivorship

Cancer Survivors Find Online and Telephone Communication With Health-Care Professionals Beneficial

Researchers from the School of Health Sciences at the University of Surrey have completed the first-ever systematic review of cancer survivors’ experience of online and telephone telehealth interventions in cancer care, a new study by Cox et al in the Journal of Medical Internet...

Albert H. Owens, Jr, MD, Pioneering Johns Hopkins Oncologist, Dies

Albert H. Owens, Jr, MD, a Johns Hopkins oncologist who played a leadership role in developing oncology as a scientific discipline and clinical specialty—and who also served as President of The Johns Hopkins Hospital—died January 13 at the age of 90. In the 1960s, oncology was not a word that...

pain management

Clinical Trials Actively Recruiting Patients With Cancer-Related Pain

Phase I Study Title: Qigong Mind-Body Exercise for Persistent Post-Surgical Pain in Breast Cancer Survivors: A Pilot Study Study Type: Phase I/interventional/single-group assignment Study Sponsor and Collaborators: Dana-Farber Cancer Institute, Brigham and Women’s Hospital, Spaulding...

issues in oncology

NCCN Working Group on Value Tools Presents Preliminary Findings and Recommendations

Over the past several years, the introduction of decision-making tools for patients from major cancer organizations, including ASCO and the National Comprehensive Cancer Network® (NCCN®), has been news, applauded as a step toward more patient-centered care and featured at many meetings. Next steps, ...

neuroendocrine tumors

Telotristat Ethyl: A Novel Therapy for Carcinoid Syndrome—Not a Panacea but a Step in the Right Direction

The multihumoral manifestations of neuroendocrine tumors include diarrhea, cutaneous flushing, wheezing, and right-sided valvular heart disease.1 Serotonin, a biogenic amine and product of tryptophan metabolism,2 mediates several of these symptoms.3,4 Diarrhea is a cardinal and often disabling...

prostate cancer

On the Horizon: New Tools for Prostate Cancer

The field of prostate cancer is being energized by discoveries in genetics, novel imaging techniques, and the potential of checkpoint inhibitors in the treatment of prostate cancer. Not all of these advances are currently clinically actionable, but all have the potential to change clinical...

breast cancer

Nearly Half of Patients Treated for Early-Stage Breast Cancer Report at Least One Severe Side Effect

Nearly half of women treated for early-stage breast cancer reported at least one side effect from their treatment that was severe or very severe, according to a new study published by Friese et al in Cancer. Although it might be expected for women undergoing chemotherapy, researchers found...

ASCO Releases Principles for Patient-Centered Health-Care Reform

ASCO has released “ASCO Principles for Patient-Centered Health-Care Reform,” seven recommendations designed to ensure access to high-quality cancer care amid the changing U.S. health-care delivery landscape. The principles aim to assist the new Congress and Administration, so, as they consider the...

From Azerbaijan to America: An IDEA Recipient’s Experience

Cancer takes away millions of lives every year, and in low- and middle-income countries, the high cancer mortality rate can often be attributed to scarce means and a shortage of trained professionals. Hoping to contribute my best in the fight against this disease, I chose to become an oncologist in ...

lymphoma

Expert Point of View: Stephen Ansell, MD, PhD

Stephen Ansell, MD, PhD, Chair of the Mayo Clinic Lymphoma Group, said the “exciting results” of these studies indicated that “we have come a long way in Hodgkin lymphoma.” “It’s been very gratifying to see that the excellent initial trial results with the anti–programmed cell death protein 1...

colorectal cancer
lung cancer

Potential Suboptimal Use of Guideline-Endorsed Genomic Testing in Non–Small Cell Lung and Colorectal Cancers

In a study reported in the Journal of Oncology Practice, Gray et al found that many medical oncologists did not use genomic testing endorsed by guidelines in place in 2012 and 2013 in patients with non–small cell lung cancer (NSCLC) and colorectal cancer. The study involved a survey of U.S....

skin cancer

ECCO 2017: Melanoma Death Rates Will Fall by 2050, but Number of Deaths Will Increase

By 2050, the death rates from malignant melanoma will have decreased from their current levels, but the numbers of people dying from the disease will have increased due to the aging of populations. However, if new treatments for the deadly skin cancer prove to be effective, the numbers of deaths...

gastroesophageal cancer

ECCO 2017: Breath Test Might Help Detect Stomach and Esophageal Cancers

A test that measures the levels of five chemicals in the breath has shown promising results for the detection of cancers of the esophagus and stomach in a large patient trial presented by Markar et al at the 2017 European Cancer Congress (Abstract 6LBA). Together, stomach and esophageal...

leukemia

I’m Learning to Live With Chronic Cancer

I was feeling a bit more tired than usual as the Christmas holidays approached in December 2012, but I chocked it up to the frenetic pace of the season and keeping up with caring for my two young children, ages 4 and 12. I had none of the other typical warning signs of chronic myeloid leukemia...

What Have We Got to Lose?

Tuesday morning was the regular time for the departmental meeting—an opportunity to discuss cases, troubleshoot, debrief, and expedite the necessary allied health referrals. As usual, patient cases were being discussed in alphabetical order of the attending oncologist. We were already three...

gynecologic cancers

An Ovarian Cancer Survivor’s Story

Ovarian cancer, the deadliest of gynecologic cancers, is usually diagnosed after the disease has spread. Susan Evans was a secondary English and remedial reading teacher for 32 years in Bradford, Pennsylvania. She was on several advisory boards and was recognized by the Pennsylvania Senate and...

palliative care

Canadian Study Looks at an Integrated Palliative Care Model

Although initiation of palliative care from the time of cancer diagnosis produces optimal outcomes for patients, this strategy is often not practiced. A recent Canadian study conducted in patients with advanced cancer and their caregivers examined the opinions of patients with advanced cancer and...

health-care policy

ASCO Releases Principles for Patient-Centered Health-Care Reform

ASCO has released the “ASCO Principles for Patient-Centered Health-Care Reform,” seven recommendations designed to ensure access to high-quality cancer care amid the changing U.S. health-care delivery landscape. The principles aim to assist the new Congress and Administration, so, as they consider...

health-care policy

How ASCO’s New Health Policy Fellowship Program Is Helping Shape Future Cancer Care Policy

In October 2015, ASCO launched the Health Policy Fellowship program to help the next generation of oncologists with an interest in health policy to develop the skills and experience necessary to achieve their goals and shape cancer care policy in an increasingly complicated and diverse care...

cns cancers

NCCN Publishes Patient Education Resources for Gliomas, Its First in a Series on Brain Cancer

The National Comprehensive Cancer Network® (NCCN) has published the NCCN Guidelines for Patients® and NCCN Quick Guide™ sheets for Brain Cancer–Gliomas, the first in a series of patient education resources focused on brain cancer. Published by NCCN through the support of the NCCN Foundation and in...

issues in oncology

Telemedicine: Transforming Health Care One Computer at a Time

Telehealth is the delivery of health care remotely via telecommunication tools. Its aim is to increase access to care, especially for patients with chronic diseases such as cancer and for populations for whom care is not always available. With the growing availability of broadband and portable...

Pamela Laszewski, RN, OCN, Receives 2017 ONS Excellence in Radiation Therapy Nursing Award

Pamela Laszewski, RN, OCN, Clinical Leader of Radiation at the Barbara Ann Karmanos Cancer Institute, will receive the notable 2017 Oncology Nursing Society (ONS) Excellence in Radiation Therapy Nursing Award during the Annual ONS Congress May 4–7, 2017, in Denver. The award was created to...

Jennifer Lycette, MD, Takes Pride in Delivering Cancer Care to Those Most in Need in Northwest Oregon

Born and reared in Anchorage, a city located in Southcentral Alaska, farther north than St. Petersburg, Russia, Jennifer Lycette, MD, grew up during the 1970s and 1980s. “We were fairly isolated from the lower 48. We didn’t have cable TV in Anchorage, and I remember my father would turn off the TV ...

Levine Cancer Institute Named a Planetree-Designated Patient-Centered Organization

Carolinas HealthCare System’s Levine Cancer Institute has earned a Planetree Designation, a hallmark of exceptional patient-centered care. The Planetree Designation is a key award that recognizes excellence in person-centeredness across the continuum of care and is based on evidence and standards...

issues in oncology

Addressing Discrimination and Bias in Medical Education

“As a medical student, I often felt marginalized from my medical community. I have been told that my name is ‘not American,’ fallen prey to being confused for support staff such as a janitor (even while wearing my white coat) and been asked questions like, ‘Where are you really from?’ or ‘How old...

issues in oncology
health-care policy

ASCO’s State Affiliate Council: Helping Practices to Meet the Challenges Ahead

ASCO’s State Affiliate Council serves as an advisory group to ­ASCO’s Board of Directors on issues relating to its State/Regional Affiliates and their members, and serves as a vehicle for effective communications between the Board and domestic membership. The Council is made up of physician...

ASCO Launches JCO Clinical Cancer Informatics

JCO Clinical Care Informatics (JCO CCI) will be the first ASCO journal devoted to applications of biomedical informatics to cancer care. Debra Patt, MD, MPH, MBA, the Editor-in-Chief of JCO CCI, understands how important biomedical informatics research is to the oncology field. Dr. Patt coauthored ...

ASCO Comments on Final MACRA Implementation Rule

ASCO submitted comments to the Centers for Medicare & Medicaid Services (CMS) on the agency’s final rule detailing the Quality Payment Program, which, under the Medicare Access and CHIP Reauthorization Act (MACRA), changes the way physicians are reimbursed for services provided under Medicare...

Conquer Cancer Foundation Researcher Spotlight: Vamsidhar Velcheti, MD

What if more patients with lung cancer could benefit from immunotherapy? Although progress in this area of research is exciting, unfortunately, a vast majority of patients with thoracic malignancies do not respond to this pioneering form of treatment. Vamsidhar Velcheti, MD, Assistant Professor of ...

issues in oncology

Optimizing Access to Fertility Preservation Options

Ensuring that people with cancer understand how cancer treatment could affect their fertility and what options are available for preserving fertility were widely recognized as top priorities by attendees of the 2016 Oncofertility Conference in Chicago. As detailed at the conference, means of...

multiple myeloma

Antiretroviral Agent Makes Strong Showing in Refractory Multiple Myeloma

An antiretroviral drug that is used for human immunodeficiency virus (HIV) demonstrated strong activity when combined with bortezomib (Velcade) in patients with relapsed/refractory multiple myeloma in a small multicenter phase II study presented at the 2016 American Society of Hematology (ASH)...

gastroesophageal cancer

2017 GI Cancers Symposium: PET Scans Can Inform and Improve Treatment for Patients With Esophageal Cancer

Findings from a federally funded clinical trial—CALGB 80803 (Alliance)—point to a new way to improve the outlook for patients with esophageal cancer: using positron-emission tomography (PET) scans to assess tumor response to initial chemotherapy may allow doctors to tailor further...

health-care policy
issues in oncology

ASCO Releases Principles for Patient-Centered Health-Care Reform

ASCO has released the “ASCO Principles for Patient-Centered Health-care Reform,” seven recommendations designed to ensure access to high-quality cancer care amid the changing U.S. health-care delivery landscape. The principles aim to assist the new Congress and Administration, so, as...

hepatobiliary cancer

FDA Grants Priority Review for the sNDA for Regorafenib in the Second-Line Systemic Treatment of Liver Cancer

On January 4, the U.S. Food and Drug Administration (FDA) granted Priority Review status for the supplemental New Drug Application (sNDA) for regorafenib (Stivarga) tablets for the second-line systemic treatment of patients with hepatocellular carcinoma in the United States. “Liver cancer is ...

global cancer care
issues in oncology

Exploring Practical Strategies for Cancer Care in Low-Resource Settings

One of the featured “Big Debates” at the 2016 World Cancer Congress in Paris addressed this question: Are scarce resources best applied to prevention rather than treatment? Many experts do not see prevention vs treatment in such stark terms or even as a realistic scenario. It’s a false dichotomy,...

integrative oncology

Advancing the Global Impact of Integrative Oncology

The 13th International Conference of the Society of Integrative Oncology (SIO) held in Miami, Florida, in November, drew its largest audience yet, with nearly 400 clinicians, researchers, patients, and patient advocates in integrative oncology care from 25 countries in attendance with large...

breast cancer
genomics/genetics

Genomic Landscape of Metastatic Breast Cancer Differs From That of Primary Breast Cancer

Researchers working on whole-exome and transciptome sequencing of endocrine-resistant estrogen receptor–positive metastatic breast cancer have shown that the mutational landscape differs from that of estrogen receptor–positive primary breast cancer, and these differences have the potential to...

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