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Showing 20151 - 20200Cancer on the Global Stage: Incidence and Cancer‑Related Mortality in Algeria
The ASCO Post is pleased to continue this special focus on the worldwide cancer burden. In this issue, we feature a close look at the cancer incidence and mortality rates in Algeria. The aim of this special feature is to highlight the global cancer burden for various countries of the world. For the ...
LUNGevity Foundation and Celgene Collaborate to Create Resource for Lung Cancer Caregivers
The LUNGevity Foundation and the biopharmaceutical company Celgene have joined forces to launch a new resource for caregivers of people diagnosed with lung cancer. The program, “Your Journey Together,” is a support tool focusing on the specific needs of this group and includes a series of videos,...
Peter A. Kanetsky, PhD, MPH, Named Next President of ASPO
Peter A. Kanetsky, PhD, MPH, Chair and Program Leader of Cancer Epidemiology at the Moffitt Cancer Center, has been elected as the new president for the American Society of Preventive Oncology (ASPO). He will serve as President-Elect before taking the post in March 2017. ASPO is a multidisciplinary ...
Martine Extermann, MD, PhD, Recognized for Her Work in Geriatric Oncology at Assembly in Basel, Switzerland
Martine Extermann, MD, PhD, senior member of Moffitt’s Senior Adult Oncology Program, has been honored with the Geriatric Oncology Lifetime Achievement Award, originally known as the “Preis geriatrische Onkologie für das Lebenswerk 2015,” at this year’s German, Austrian, and Swiss Congress of the...
Telotristat Etiprate Added to Standard Therapy for Carcinoid Syndrome Shows Clinical Benefit in Patients With Metastatic Neuroendocrine Tumors
The investigational drug telotristat etiprate was shown to have clinical benefit when added to somatostatin analog therapy for carcinoid syndrome not adequately controlled by long-acting somatostatin analog therapy, the current standard of care, in patients with metastatic neuroendocrine tumors....
Geriatric Oncology in Europe: A Commitment to Improving Cancer Care for Older Patients
In Europe, the field of geriatric oncology has a long history of development, and its organization and implementation continue to improve every day. This would not have happened without the strong commitment of national authorities to health policies, a critical success factor. Four Missions In...
Lewis Cantley, PhD, Receives 2015 AACI Distinguished Scientist Award
The Association of American Cancer Institutes (AACI) presented the AACI Distinguished Scientist Award to Lewis Cantley, PhD, on October 26, during the 2015 AACI/Cancer Center Administrators Forum Annual Meeting, in Washington, DC. A cell biologist and biochemist who serves as The Margaret and...
Why Melanoma Rates Are Increasing in Adolescents and Young Adults, Especially Among Females
The incidence of melanoma among children, adolescents, and young adults has reached epidemic proportions, increasing more than 250% over the past 4 decades, with young females at highest risk for the deadly cancer, according to a study1 by researchers at Roswell Park Cancer Institute in Buffalo,...
UCLA and VA Launch Program to Enhance Cancer Care for Veterans
A new collaboration between the University of California, Los Angeles (UCLA) and the Veterans Affairs (VA) Greater Los Angeles Healthcare System will provide access to the latest therapeutic cancer clinical trials and state-of-the-art care for men and women who have served in the armed forces. The...
Survival and Bevacizumab in Early Breast Cancer: Time to Reconsider?
In metastatic HER2-negative breast cancer, several trials have shown that the addition of the anti–vascular endothelial growth factor (VEGF) monoclonal antibody bevacizumab (Avastin) to different chemotherapy regimens significantly improved response rates and progression-free survival by various...
ASH Elects New Leadership to Its Executive Committee
The American Society of Hematology (ASH) has announced the election of three new members to its Executive Committee, the governing body of the organization, for terms beginning after the 2015 ASH Annual Meeting, taking place December 5–8 in Orlando. Alexis A. Thompson, MD, MPH, will serve a 1-year...
ASCO Recommendations for Use of White Blood Cell Growth Factors: What Remains the Same and What Has Been Modified
Neutropenic complications remain the main dose-limiting toxicity of cancer chemotherapy treatment and are associated with considerable morbidity, mortality, and costs.1 Although patients who have experienced a prior neutropenic event are at increased risk of subsequent events, several studies have...
ASCO Clinical Practice Guideline Update: Recommendations for the Use of White Blood Cell Growth Factors
ASCO has issued a clinical practice guideline update on use of hematopoietic colony-stimulating factors, as reported in the Journal of Clinical Oncology by Thomas J. Smith, MD, FACP, FASCO, FAAHMP, and colleagues.1 This update to the ASCO 2006 guideline was based on a systematic review of...
Maciej Lesniak, MD, Named Chair of Neurological Surgery at Northwestern
Maciej (Matt) Lesniak, MD, has been named the Michael J. Marchese Professor and Chair of the Departments of Neurological Surgery at Feinberg School of Medicine and Northwestern Memorial Hospital in Chicago. Prior to joining Northwestern, Dr. Lesniak was a Professor of Neurosurgery, Neurology, and...
Victoria Seewaldt, MD, Joins City of Hope
Breast cancer and ovarian cancer specialist, Victoria L. Seewaldt, MD, has joined City of Hope as the Ruth Ziegler Chair in Population Sciences. Dr. Seewaldt, who is a specialist in developing risk models for aggressive cancers, will also serve as the Associate Director of the Comprehensive Cancer...
Nancy A. Speck, PhD, Named Chair, Cell and Developmental Biology, Perelman School of Medicine/University of Pennsylvania
Nancy A. Speck, PhD, has been named Chair of the Department of Cell and Developmental Biology in the Perelman School of Medicine at the University of Pennsylvania. She is also the Associate Director of Penn’s Institute for Regenerative Medicine, Co-Leader of the Hematologic Malignancies Program at...
The Breast Cancer Research Foundation Names Marc Hurlbert, PhD, as Chief Mission Officer
The Breast Cancer Research Foundation (BCRF) announced that it has appointed Marc Hurlbert, PhD, as its new Chief Mission Officer (CMO). Formerly the Executive Director of the Avon Breast Cancer Crusade, Dr. Hurlbert succeeds Margaret (Peg) Mastrianni, who will retire in January 2016 after serving...
End-of-Life Clinical Decisions Still Need Conversations About Improving Care
In 2014, the Institute of Medicine report Dying in America: Improving Quality and Honoring Individual Preferences Near the End of Life called for more conversations about improving care for those who are dying. Improving the care of the imminently dying is an important issue in the oncology...
Ovarian Cancer Trialists Forming Work Group to Standardize Definition of Pathologic Complete Response
Ovarian cancer clinical trialists are forming a working group to develop a standard definition of pathologic complete response in ovarian cancer treated with neoadjuvant chemotherapy. Such agreement within the field potentially would enable the U.S. Food and Drug Administration (FDA) to consider...
National Coalition for Cancer Survivorship Honors Richard Pazdur, MD, and Ellen Goodman
On October 21 in Washington, DC, the National Coalition for Cancer Survivorship (NCCS) hosted a reception to honor Richard Pazdur, MD, and Ellen Goodman. NCCS Chief Executive Officer, Shelly Fuld Nasso, welcomed attendees to the special awards reception. NCCS Public Service Leadership Award The...
NYU Langone Appoints Alec Kimmelman, MD, PhD, as Chair of Radiation Oncology
Renowned clinician-scientist Alec Kimmelman, MD, PhD, has been named Chair of the Department of Radiation Oncology at NYU Langone Medical Center. His appointment is effective February 1, 2016. Dr. Kimmelman joins the Laura and Isaac Perlmutter Cancer Center at NYU Langone following a distinguished...
Beth Israel Deaconess Medical Center Names Manuel Hidalgo, MD, PhD, Clinical Director of the Cancer Center and Chief of Hematology-Oncology
Manuel Hidalgo, MD, PhD, an oncologist whose work in experimental cancer therapy and tumor model development has led to key advances in the treatment of pancreatic cancer, has been named Director of the Leon V. & Marilyn L. Rosenberg Clinical Cancer Center and Chief of the Division of...
Sandra L. Wong, MD, MS, Named Chair of Surgery at Geisel School of Medicine and Dartmouth-Hitchcock
Sandra L. Wong, MD, MS, the William W. Coon Professor of Surgical Oncology and Associate Chair of Clinical Affairs at the University of Michigan Health System, has been named Chair of Surgery at Dartmouth-Hitchcock and the Geisel School of Medicine at Dartmouth and Senior Vice President of the...
FDA Approves Ipilimumab in Adjuvant Treatment of Stage III Melanoma
On October 28, 2015, the U.S. Food and Drug Administration (FDA) approved the monoclonal antibody ipilimumab (Yervoy) for the adjuvant treatment of patients with cutaneous melanoma with pathologic involvement of regional lymph nodes of more than 1 mm who have undergone complete resection, including ...
PD-1/PD-L1 Inhibitors Show Promise in Additional Tumor Types
While inhibitors of programmed cell death protein 1 (PD-1) or its ligand (PD-L1) are becoming established in melanoma, non–small cell lung cancer, and renal cell carcinoma, their efficacy is also being evaluated in numerous other tumor types, with promising results, according to studies presented...
FDA Approves Liposomal Irinotecan for Advanced Pancreatic Cancer
The U.S. Food and Drug Administration has approved irinotecan liposome injection (Onivyde), in combination with fluorouracil (5-FU) and leucovorin, to treat patients with metastatic pancreatic cancer who have been previously treated with gemcitabine-based chemotherapy. The effectiveness of...
FDA Approves Trabectedin for Advanced Liposarcoma and Leiomyosarcoma
The U.S. Food and Drug Administration has approved the novel chemotherapy drug trabectedin (Yondelis) for the treatment of specific soft-tissue sarcomas—liposarcoma and leiomyosarcoma—that are unresectable or metastatic. Trabectedin is a novel marine antineoplastic alkaloid with a unique mechanism ...
Debate Over Physician-Assisted Suicide Continues, State by State
In 1997, after surviving a storm of high-court legal challenges, Oregon’s Death With Dignity Act went into effect, making Oregon the first American state to legalize physician-assisted suicide. The Supreme Court ruled that there was no right to assisted suicide in the Constitution but implied that...
Is Health Care in the United States a Basic Human Right or an Entitlement?
Mercy Killers is a one-man show that details the consequences of a medical health-care catastrophe (breast cancer) in a family.1 This disturbing fictional account is actually a daily event in cancer centers: losing insurance for technicalities, losing a home because of an inability to pay the...
Intensity-Modulated Radiotherapy Gains Ground for Treatment of Stage III Non–Small Cell Lung Cancer
Intensity-modulated radiation therapy appears to be preferable to three-dimensional (3D) conformal radiation therapy as part of treatment for patients with locally advanced (stage III) non–small cell lung cancer (NSCLC). Compared with 3D conformal radiotherapy, intensity-modulated radiotherapy...
2015 Recipients of the Susan G. Komen Brinker Awards for Scientific Distinction to Present Lectures at San Antonio Breast Cancer Symposium
Susan G. Komen has announced the recipients of the 2015 Brinker Awards for Scientific Distinction, which honors leading scientists who have made the most significant advances in breast cancer research and medicine. The 2015 recipients of the Brinker Awards for Scientific Distinction are Myles A....
Expect Questions About Updated Breast Cancer Screening Guidelines
As Chair of the American Cancer Society (ACS) panel that issued an updated guideline for breast cancer screening, Kevin C. Oeffinger, MD, has answered questions and offered perspective on the updated guideline and its development for The New York Times, USA Today, and other major media outlets. As...
Updated ACS Breast Cancer Screening Guideline Recognizes Greater Role for Individual’s Values and Preferences
The reactions to the updated breast cancer screening guideline from the American Cancer Society (ACS) have been many, varied, and not consistently favorable but not surprising to Kevin C. Oeffinger, MD, who chaired the ACS panel that issued the guideline. Breast cancer screening “is an area that...
ASH Recognizes Curt Civin, MD, and Craig Kitchens, MD, MACP, for Outstanding Mentorship
The American Society of Hematology (ASH) will honor Curt Civin, MD, and Craig Kitchens, MD, MACP, with 2015 Mentor Awards at the 57th ASH Annual Meeting and Exposition in Orlando, Florida, for their sustained, outstanding commitment to the training and career development of early-career...
Stepping Back in Medical History: A Groundbreaking Surgeon’s Battle With the Establishment
Bookmark Title: Dr. Mütter’s Marvels: A True Tale of Intrigue and Innovation at the Dawn of Modern MedicineAuthor: Cristin O’Keefe AptowiczPublisher: Gotham BooksPublication date: September 8, 2015Price: $17.00, paperback; 384 pages In the late 1740s, John Wesley—a British evangelist and...
2015 Oncology Meetings
DECEMBER Markers in Cancer 2015December 1-2 • Brussels, Belgium For more information: http://markersincancer.org 9th European Colorectal Congress (ECC)December 1-4 • St.Gallen, Switzerland For more information: www.colorectalsurgery.eu Advances in Cancer ImmunotherapyTMDecember 4 • New Orleans,...
ASH Selects Medical Students and Residents for HONORS Award
The American Society of Hematology (ASH) has announced the names of 18 medical students and 10 residents selected to receive a 2015 ASH HONORS Award. The ASH HONORS Award aims to support hematology research projects for North American medical students and residents who are interested in hematology...
Patient Guides Available Through ASCO University Bookstore
ASCO Answers: Managing the Cost of Cancer Care explains the various costs associated with cancer treatment, including health-care coverage through the Affordable Care Act. It also provides a list of financial resources available to help offset expenses related to care and tips for organizing...
CAR T-Cell Immunotherapy Saved My Life
I have always prided myself on being healthy and fit, so when I started experiencing a chronic cough, difficulty breathing, and pain in my ribs and back, I thought they were the inevitable symptoms of a severe cold. At 42 and the mother of three children, it was inconceivable to me that I could...
Barbara Furie, PhD, and Bruce Furie, MD, to Present 2015 ASH E. Donnall Thomas Lecture
The American Society of Hematology (ASH) will honor Barbara Furie, PhD, of Harvard Medical School, and Bruce Furie, MD, of Beth Israel Deaconess Medical Center and Harvard Medical School, with the 2015 E. Donnall Thomas Lecture for their groundbreaking research in hemostasis and thrombosis over the ...
Daratumumab Approved in Multiple Myeloma
The U.S. Food and Drug Administration has granted accelerated approval for daratumumab (Darzalex) to treat patients with multiple myeloma who have received at least three prior treatments, including a proteasome inhibitor and an immunomodulatory agent, or who are double-refractory to a proteasome...
FDA Approves Cobimetinib in Combination With Vemurafenib for Metastatic Melanoma
On November 10, 2015, the U.S. Food and Drug Administration (FDA) approved the MEK inhibitor cobimetinib (Cotellic) in combination with the BRAF inhibitor vemurafenib (Zelboraf) to treat metastatic or unresectable melanoma in patients whose tumors express the BRAF V600E or V600K mutation. Approval...
A Selfless Act
The ASCO Post is pleased to reproduce installments of the “Art of Oncology” as published previously in the Journal of Clinical Oncology (JCO). These articles focus on the experience of suffering from cancer or of caring for people diagnosed with cancer, and they include narratives, topical essays,...
Engaging Clinicians in the Collection of Cancer Registry Data to Improve Clinical Research
In June, the Commission on Cancer of the American College of Surgeons published a revision of its Facility Oncology Registry Data Standards (FORDS) manual, which contains all the data items, codes, and rules to abstract data into cancer registries at the more than 1,500 Commission on...
The Importance of Supporting the Role of Women Leaders in Oncology
I am honored to be the 52nd President of ASCO and thrilled to have followed in the steps of six remarkable women to hold this important leadership position in a professional Society that represents nearly 40,000 oncologists around the world caring for people with cancer. My six female predecessors...
Pilot Study: Research Team Used Focused Ultrasound to Open Blood-Brain Barrier in Patient With Malignant Brain Tumor
A team at Sunnybrook Health Sciences Centre in Toronto has used focused ultrasound to enable temporary and targeted opening of the blood-brain barrier, allowing the more effective delivery of chemotherapy into a patient’s malignant brain tumor. This is the first known report of the noninvasive...
ASCO Launches TAPUR to Assess the Off-Label Use of Targeted Therapies for Patients With Advanced Cancers
Two years ago, Richard L. Schilsky, MD, FACP, FASCO, Chief Medical Officer of ASCO, proposed a unique clinical trial concept during an educational session on the challenges of delivering precision medicine services in a community setting at ASCO’s Annual Meeting. The idea was to design a clinical...
Diet and Cancer: How Will We Make Progress?
Not only is breast cancer among the most common cancers in women, but it is also one of the most common causes of premature death. Rates of death from the disease vary widely around the world, reflecting variations in risk, screening, and access to highest quality treatment. Although female gender...
American Board of Internal Medicine Names Richard G. Battaglia, MD, FACP, Chief Medical Officer
The American Board of Internal Medicine (ABIM) announced that Richard G. Battaglia, MD, FACP, has joined the senior leadership team of the organization and will serve as Chief Medical Officer, leading ABIM’s effort to incorporate feedback from practicing physicians and key stakeholders into...
The X-Ray Era: 1901–1915
A Century of Progress The text and photographs on this page are excerpted from a four-volume series of books titled Oncology Tumors & Treatment: A Photographic History, by Stanley B. Burns, MD, FACS. The photos below are from the volume titled “The X-ray Era: 1901–1915.” To view additional...
