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multiple myeloma

FDA Grants Orphan Drug Designation to Galinpepimut-S for Treatment of Multiple Myeloma

The U.S. Food and Drug Administration (FDA) recently granted Orphan Drug designation to galinpepimut-S for the treatment of multiple myeloma. The drug is licensed from Memorial Sloan Kettering Cancer Center and targets the Wilms tumor 1 (WT1) protein, which is present in an array of tumor...

Conquer Cancer 2018 Awards Presented at ASCO Annual Meeting

The Conquer Cancer Foundation of the ASCO recently announced the recipients of its 2018 ASCO Annual Meeting Merit Awards, Medical Student Rotations for Underrepresented Populations (MSR), Resident Travel Awards for Underrepresented Populations (RTA), and Long-term International Fellowship (LIFe)....

Former Chair of ASCO’s Health Disparities Committee, Karen M. Winkfield, MD, PhD, Faced Her Own Barriers

Nationally regarded radiation oncologist Karen M. Winkfield, MD, PhD, was born and reared in Wheatley Heights, a suburban hamlet on Long Island, New York, that shares borders with the prosperous community of Dix Hills and one of the Island’s lowest-income towns, Wyandanch. “I was fortunate to live ...

ASCO, ABIM Collaborate on Pathway to Maintenance of Board Certification

ASCO and the American Board of Internal Medicine (ABIM) have announced that they are working to co-create a pathway to provide doctors with a flexible way to maintain board certification. The work with ASCO reflects real progress in ABIM’s efforts to collaborate with medical societies. Beginning in ...

genomics/genetics

NIH Completes In-Depth Genomic Analysis of 33 Cancer Types

Researchers funded by the National Institutes of Health (NIH) have completed a detailed genomic analysis, known as the PanCancer Atlas, on a data set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer, according to a release issued by the NIH late last...

breast cancer

Education Came First for Breast Cancer Expert Beverly Moy, MD, MPH, Daughter of Chinese Immigrants

Beverly Moy, MD, MPH, grew up in Brooklyn, New York, in a modest working-class home. Both her parents were immigrants from China. “Education is highly prized in Chinese culture, and my home life was no exception. I didn’t speak any English when I began kindergarten, so that was a bit challenging,...

New Fellows Selected for ASCO’s 2018-2019 Health Policy Fellowship Program

ASCO recently announced that Trevor Royce, MS, MD, MPH, and Sheetal Kircher, MD, have been selected for the ASCO Health Policy Fellowship Program.  Now entering its third year, the fellowship program offers oncologists the opportunity to gain the knowledge-base, skills, and experience necessary to...

solid tumors
hematologic malignancies

FDA Oncology Drug Approvals Granted Between June 2017 and May 16, 2018

Over the past year (June 2017–May 2018), the U.S. Food and Drug Administration (FDA) granted approval to a number of new oncology drug products, including several biosimilar products. Here we provide the labeling approved for these novel drugs and new indications.  EPOETIN ALFA-EPBX (RETACRIT)...

geriatric oncology

A Love of Older Patients With Cancer Drives a Career Path for Arti Hurria, MD, FASCO

Arti Hurria, MD, FASCO, who is Director of City of Hope’s Center for Cancer and Aging, is a first generation of immigrant parents from India. “My parents left India and moved from England to Canarsie, Brooklyn, where I was born. When I was 8, my family moved to Southern California, partly due to...

Husband and Wife Leave a Giant Legacy in Oncology

The remarkable careers of Jimmie C. Holland, MD, and James F. Holland, MD, spanned collectively for more than a century, leaving an indelible footprint in oncology clinical care and research. Synonymous with cancer care itself, the Hollands were a living documentary of the rich and dramatic history ...

global cancer care

International Oncologist Nagi S. El Saghir, MD, FACP, Returned Home to Make a Difference in Lebanon and Worldwide

Internationally renowned expert on the early detection, prevention, and treatment of younger women with breast cancer, Nagi S. El Saghir, MD, FACP, FASCO, was born on January 5, 1953, in Bint Jbeil, a village in southern Lebanon. His parents moved to Beirut in 1948, at the height of the...

prostate cancer

AUA 2018: Is Prostate Cancer Screening and Risk Stratification Moving Beyond the PSA Test?

New diagnostic tests for prostate cancer, as well as new information about the impact of the U.S. Preventive Services Task Force recommendations on prostate cancer screening, were presented at the 113th Annual Meeting of the American Urological Association (AUA). PSA Screening of African American...

prostate cancer

AUA 2018: Apalutamide Significantly Reduced Risk of PSA Progression in Patients With Nonmetastatic Castration-Resistant Prostate Cancer

A post-hoc analysis from the phase III SPARTAN study that showed treatment with apalutamide (Erleada) significantly reduced the risk of prostate-specific antigen (PSA) progression in patients with nonmetastatic castration-resistant prostate cancer (CRPC) who had a rapidly rising PSA while receiving ...

prostate cancer

AUA 2018: Use of MRI for Prostate Cancer Screening and Management

Use of magnetic resonance imaging (MRI) in the diagnosis of prostate cancer is increasing and brings added value to screening and surveillance, according to new studies presented this year during the 113th Annual Meeting of the American Urological Association (AUA). Four studies highlighting the...

prostate cancer

AUA 2018: Panel Discusses New Research on Prostate Cancer Management Protocols and Treatments

Researchers presented new findings on a Korean Food and Drug Administration (KFDA)-approved robotic system, safety of testosterone therapy after prostate cancer, and active surveillance protocol for low-risk prostate cancer patients at the 113th Annual Meeting of the American Urological Association ...

prostate cancer

AUA 2018: More Than 40% of Prostate Biopsies May Have Been Avoided With Use of Assay for Detection

A multicenter study that validated the clinical performance of IsoPSA—a new blood test that has proven to be more accurate in predicting overall risk of prostate cancer than standard prostate-specific antigen (PSA)—was presented at the 13th Annual Meeting of the American Urological...

issues in oncology

ASCO Launches Its Education Scholars Program

Education is such an integral part of ASCO’s strategic plan to reduce the burden of cancer for all patients, it is incorporated into the Society’s mission statement to “conquer cancer through research, education, and promotion of the highest patient care.” In 2017, ASCO’s Board of Directors voted...

Roger Lo, MD, PhD, Receives American Skin Association Award for Skin Cancer Research

THE AMERICAN SKIN ASSOCIATION (ASA) recently announced Roger Lo, MD, PhD, of the David Geffen School of Medicine at the University of California (UCLA), as the recipient of the Abby S. and Howard P. Milstein Innovation Award for Melanoma/Non-Melanoma Skin Cancer Research.  The award is available...

AACR Honors Recipients of 2018 Scientific Achievement Awards and Lectureships

THE AMERICAN ASSOCIATION for Cancer Research (AACR) honors the following cancer researchers and clinicians who were recognized for their scientific achievements during the AACR Annual Meeting 2018:   Isaiah J. Fidler, DVM, PhD, FAACR, AACR President (1984-1985), Fellow of the AACR Academy and...

ACS and MRA Fund Research on Adverse Effects of Immunotherapy

THE AMERICAN CANCER SOCIETY (ACS) and the Melanoma Research Alliance (MRA) recently selected a group of scientists to receive newly established research grants to investigate the adverse effects associated with checkpoint inhibitor cancer treatments. The grants are funded by MRA and ACS under a...

American Cancer Society Awards New Research and Training Grants

THE AMERICAN CANCER Society has approved funding for 110 grants totaling $47,624,000 to researchers and health professionals across 72 institutions nationwide in the first of 2 grant cycles for 2018. Of these grants, 101 are new and 9 are renewals of previous grants.  Two individuals have been...

lung cancer

Stage IV Lung Cancer Did Not Stop Me From Climbing Mera Peak

A veteran mountain climber and skier, I’ve been healthy for most of my 61 years, so it was especially shocking to experience a bout of shortness of breath during a moderately intense mountain bike ride with my wife, Jan, in the spring of 2014. A never-smoker, I was used to climbing up high mountain ...

lung cancer

High–Nicotine-Dependent Smokers Less Likely to Quit After Lung Cancer Screening

A new study by Rojewski et al in CHEST investigated the relationships between the degree of nicotine dependence and both the likelihood of successfully quitting smoking and clinical outcomes in a cohort of screened patients. The study found that patients with a higher nicotine dependence...

bladder cancer
immunotherapy

FDA Identifies Efficacy Issue in Clinical Trials of Pembrolizumab or Atezolizumab as Monotherapy in Urothelial Cancer With Low Expression of PD-L1

On May 18, the U.S. Food and Drug Administration (FDA) alerted health-care professionals, oncology clinical investigators, and the public about decreased survival associated with the use of pembrolizumab (Keytruda) or atezolizumab (Tecentriq) as monotherapy in clinical trials to treat patients with ...

Cancer Support Community Welcomes Kevin Stein, PhD, FAPOS, as Executive Director of Research and Training Institute

The Cancer Support Community recently announced the addition of Kevin Stein, PhD, FAPOS, as Executive Director of its Research and Training Institute. Dr. Stein is Associate Professor in the Behavioral Sciences and Health Education Department of the Rollins School of Public Health at Emory...

Antoni Ribas, MD, Recognized for Research in Cancer Immunology

Antoni Ribas, MD, Professor of Medicine and Director of the Tumor Immunology Program at the University of California Jonsson Comprehensive Cancer Center, has been awarded the sixth American Association of Cancer Research–Cancer Research Institute Lloyd J. Old Award in Cancer Immunology. The award...

Visible Ink Celebrates 10 Years of Live Patient Performances

On April 16, 2018, Memorial Sloan Kettering Cancer Center (MSK) in New York hosted the annual Visible Ink live performances at The Kaye Playhouse at Hunter College. The evening marked the 10th anniversary of the ongoing one-on-one writing program for patients undergoing cancer treatment at MSK....

lung cancer

Treatment of Malignant Pleural Mesothelioma: ASCO Clinical Practice Guideline

As reported by Hedy L. Kindler, MD, of the University of Chicago, and colleagues in the Journal of Clinical Oncology, ASCO has released a clinical practice guideline on the treatment of malignant pleural mesothelioma.1 The guideline was based on a systematic literature search and expert panel...

Stand Up To Cancer Launches Research Team to Detect Precursor Conditions of Multiple Myeloma

Stand Up To Cancer (SU2C) announced a $10 million award to a Stand Up To Cancer Dream Team focused on revolutionizing the treatment of multiple myeloma through the early detection of precursor conditions. In the hope of developing therapies to prevent myeloma in high-risk populations, the project...

hematologic malignancies
immunotherapy

Logistics of CAR T-Cell Therapy in Real-World Practice

With the U.S. Food and Drug Administration (FDA) approvals of tisagenlecleucel (Kymriah)1 and axicabtagene ciloleucel (Yescarta),2 chimeric antigen receptor (CAR) T-cell therapy has moved into real-world practice, offering new potentially curative options for incurable hematologic malignancies. Its ...

Focus on the Tennessee Oncology Practice Society

The Tennessee Oncology Practice Society (TOPS) is among the oldest and one of many politically active ASCO State Affiliates. Founded in 1990, the organization has since been a voice for Tennessee’s diverse community of oncology professionals, advocating for patient access to the best available care ...

symptom management
survivorship
integrative oncology

Treating Insomnia in Cancer Survivors

A Patient-Centered Outcomes Research Institute–supported randomized clinical trial of cancer survivors showed that 8 weeks of either acupuncture or cognitive behavioral therapy for insomnia (CBT-I) decreased the severity of insomnia among cancer survivors, though improvements were greatest among...

supportive care
integrative oncology

Supporting Patients During and After Cancer Treatment: Evidence-Informed Approach to Lifestyle and Behavior Change

The ASCO Post’s Integrative Oncology series is intended to facilitate the availability of evidence-based information on integrative and complementary therapies sometimes used by patients with cancer. In this installment, Lorenzo Cohen, PhD, and Alison Jefferies, BA, MEd, summarize research...

Florida Cancer Centers Awarded $1.36 Million to Minimize Disparities in Pancreatic Cancer

The Florida Department of Health’s James and Esther King Biomedical Research Program has granted Moffitt Cancer Center, the University of Florida Health Cancer Center, the Sylvester Comprehensive Cancer Center at the University of Miami, and numerous collaborating centers with $1.36 million to...

ACCP Statement on Organ-Impaired Patients in Oncology Trials

The American College of Clinical Pharmacology (ACCP) recently published a Policy Statement reviewing ways in which clinical pharmacology can and should make an effort to include organ-impaired patients in oncology trials. The announcement identifies key discussions needed among industry,...

New International Translations of NCCN Guidelines for Patients

The National Comprehensive Cancer Network® (NCCN®) has published a newly translated Italian version of the NCCN Guidelines for Patients® for stomach cancer, funded by No Stomach for Cancer. Over the past year, the NCCN Foundation also worked with the Kidney Cancer Association to translate patient...

issues in oncology

Closing the Gap in Oncology Care for Adolescents and Young Adults

During her presentation “Adolescent and Young Adult Survivorship: What Do We Still Need to Know?” at the 2017 Cancer Survivorship Symposium: Advancing Care and Research, Emily S. Tonorezos, MD, MPH, a general internist in the Adult Long-Term Follow-Up Program at Memorial Sloan Kettering Cancer...

St. Jude Cloud, Largest Public Repository of Pediatric Cancer Genomics Data, Launched for Researchers Worldwide

On April 12, St. Jude Children’s Research Hospital launched the St. Jude Cloud, an online data-sharing and collaboration platform that provides researchers access to the world’s largest public repository of pediatric cancer genomics data. Developed as a partnership among St. Jude, DNAnexus, and...

leukemia

Molecular Minimal Residual Disease Detection Shows Further Promise in Acute Myeloid Leukemia

Extended next-generation sequencing genomic profiling in acute myeloid leukemia (AML) has revealed remarkable heterogeneity and molecular complexity of the disease and provided critical insights into the genetic mechanisms underpinning of preleukemic and leukemic pathogenesis.1,2 Despite...

pancreatic cancer

PARP Inhibitor Shows Promise in Patients With BRCA-Mutated Pancreatic Cancer

A targeted therapy that has been effective in fighting ovarian cancer in women, including those with BRCA1 and BRCA2 mutations, may also help patients with aggressive pancreatic cancer who harbor these mutations and have few or no other treatment options. An international team of researchers was...

legislation

Childhood Cancer STAR Act Approved by Senate and House

On May 22, the Childhood Cancer Survivorship Treatment Access and Research (STAR) Act was passed by the Senate and House and is now being sent to President Donald Trump to be signed into law. As the most comprehensive childhood cancer bill ever introduced to Congress, the Childhood Cancer STAR Act...

ASCO Through the Years: Past Presidents

Over the years many great oncology leaders have served at the helm as ASCO President. We recognize these individuals here, and extend our gratitude for their service and efforts to champion high-quality cancer care. 2018-2019: Monica M. Bertagnolli, MD 2017-2018: Bruce E. Johnson, MD 2016-2017:...

NCCN Names Wui-Jin Koh, MD, New Chief Medical Officer

The National Comprehensive Cancer Network® (NCCN®) has named Wui-Jin Koh, MD, as Senior Vice President, Chief Medical Officer, a newly created position. Dr. Koh will add additional physician representation at NCCN headquarters, which includes Chief Executive Officer Robert W. Carlson, MD. Dr. Koh...

gynecologic cancers

How a Recent Study Heats up the Debate Over Intraperitoneal Chemotherapy in Newly Diagnosed Advanced Ovarian Cancer

Based on pharmacokinetic and preclinical data, there appears to be a biologic advantage to the use of intraperitoneal chemotherapy in treating some malignancies confined to the abdomen. Since most ovarian, fallopian tube, and peritoneal cancers present and recur in the peritoneal cavity, this...

The American Society of Clinical Oncology at a Glance

The American Society of Clinical Oncology (ASCO) held its first scientific Annual Meeting on April 9, 1965, in the Bellevue Stratford Hotel in Philadelphia. More than 70 members and invited guests attended the inaugural event, which featured three presentations on leukemia and multiple myeloma. The ...

2018 Fellows of the American Society of Clinical Oncology (FASCO) Recognized During Annual Meeting in Chicago

The Fellow of the American Society of Clinical Oncology (FASCO) distinction recognizes ASCO members for their extraordinary volunteer service, dedication, and commitment to ASCO. Their efforts benefit ASCO, the specialty of oncology, and, most importantly, the individuals at risk for, or with...

kidney cancer

Update on ATLAS Trial of Axitinib for RCC Recurrence Risk

Pfizer recently announced that the independent data monitoring committee for the phase III ATLAS trial, which is evaluating axitinib (Inlyta) as adjuvant therapy for patients at high risk of recurrent renal cell carcinoma (RCC) after nephrectomy, recommended stopping the trial at a planned interim...

ASCO Honors Leaders in Cancer Care With 2018 Special Awards

ASCO AND ASCO’s Conquer Cancer Foundation recognized winners of ASCO’s 2018 Special Awards and Conquer Cancer’s Women Who Conquer Cancer Mentorship Awards during the 2018 ASCO Annual Meeting, June 1 to June 4, in Chicago. The recipients of these awards included researchers, patient advocates, and...

Fox Chase Cancer Center Announces 2018 Award Recipients for Translational Clinical Protocol Development

Fox Chase Cancer Center recently announced the awardees of the 2018 translational clinical protocol development based on basic and preclinical research results. Translational research disease groups were created with a multidisciplinary group of clinical and research-based faculty, with a focus on...

Help Your Patients Catch Up on the Latest Research From the 2018 ASCO Annual Meeting

The Cancer.Net Blog (available at Cancer.Net/Blog) features daily posts covering research highlighted at the 2018 ASCO Annual Meeting where patients and caregivers can learn what this research means for their care and treatment. The Cancer.Net Blog also offers continuing coverage from the ASCO...

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