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SSO 2021 International Conference on Surgical Cancer Care

Colorectal Cancer

Better Responses to Hepatic Arterial Infusion Therapy Among Patients With KRAS Wild-Type Metastatic Colorectal Cancer

Patients with colorectal cancer and unresectable liver metastases and KRAS wild-type disease experienced better responses to hepatic arterial infusion pump chemotherapy than did patients with KRAS mut...

Global Cancer Care
COVID-19

Global Responses to COVID-19 Pandemic–Related Disruptions in Cancer Care

COVID-19 pandemic–related disruptions in cancer diagnosis, treatment, and research have varied worldwide and so have the responses to those disruptions. During the Society of Surgical Oncology (SSO) 2...

Gastrointestinal Cancer

Adjuvant Imatinib Therapy Offers Survival Benefit in Patients With Resected GIST, but Team Effort May Be Needed to Reduce Early Discontinuation Rates

Clinical trial data show that adjuvant imatinib improves recurrence-free survival as well as overall survival, when administered for at least 3 years, among patients who undergo a macroscopically comp...

Hepatobiliary Cancer
Genomics/Genetics

Actionable Mutations Identified in Majority of Genome-Sequenced Resected Cholangiocarcinomas

Tumor genomic profiling of resected cholangiocarcinomas may reveal mutations targetable with agents currently being used for other cancers, according to the results of a study presented at the Society...

Skin Cancer
Immunotherapy

Study Finds Adjuvant Immunotherapy of Benefit to Patients With Stage IIB/C Melanoma

A significant survival advantage accrued to patients with stage IIB and IIC cutaneous melanoma who received adjuvant immunotherapy, a large retrospective cohort study reported at the Society of Surgic...

Issues in Oncology
Genomics/Genetics

Expanding Role of Liquid Biopsies in Cancer Detection and Therapeutics: Now and in the Near Future

“It is possible that within the next several years, perhaps 75% of cancers can be detected by screening,” Bert ­Vogelstein, MD, PhD, projected at the Society of Surgical Oncology (SSO) 2021 Internatio...

Gastrointestinal Cancer
Health-Care Policy

Medicaid Expansion Is Associated With Earlier Diagnosis of Gastric Cancer, Improved Survival

Medicaid expansion caused a decrease in uninsured patients and led to an earlier diagnosis of gastric cancer with an associated increase in 1-year survival, according to research presented by Zhu et a...

Gastroesophageal Cancer
Gastrointestinal Cancer
Immunotherapy

Adjuvant Nivolumab in Resected Esophageal or Gastroesophageal Junction Cancer Following Neoadjuvant Chemoradiation Therapy

Adjuvant nivolumab is the first therapy to provide a statistically significant and clinically meaningful improvement in disease-free survival in patients with resected esophageal and gastroesophageal ...

Skin Cancer

Surgical Management of Melanoma With the Advent of Adjuvant Systemic Therapy

The results of a large cohort study suggest that a proportion of patients with cutaneous melanoma could potentially avoid sentinel node biopsy, according to data presented by Moncrieff et al at the So...

Colorectal Cancer
Genomics/Genetics

KRAS Mutation Status May Predict Outcomes After Hepatic Arterial Infusion Pump Therapy for Unresectable Colorectal Liver Metastases

KRAS mutational status in patients with unresectable liver metastases from colorectal cancer predicts a worse response to hepatic arterial infusion (HAI) pump chemotherapy, according to research prese...

Breast Cancer

DCIS Biologic Risk Signature May Predict Risk of Recurrence and Radiation Benefit After Breast-Conserving Surgery

Women with ductal carcinoma in situ (DCIS) and elevated decision scores had a significantly higher risk of ipsilateral breast events and a greater relative benefit from radiation therapy compared to w...

Skin Cancer
Immunotherapy

Utilization and Survival Benefit of Adjuvant Immunotherapy for Resected High-Risk Stage II Melanoma

An observational study of 10,592 patients from the National Cancer Database with stage IIB/IIC melanoma who had undergone surgical resection demonstrated a significant survival advantage with immunoth...

Breast Cancer

Improving the Prognostic Accuracy of Residual Cancer Burden After Neoadjuvant Chemotherapy for Breast Cancer

An analysis of 546 patients with breast cancer who received neoadjuvant chemotherapy demonstrated that residual cancer burden is prognostic for overall survival, recurrence-free survival, and distant ...

Colorectal Cancer
Gastroesophageal Cancer

Circulating Hybrid Cells May Help to Monitor Treatment Response in Patients With Rectal and Esophageal Cancers

An analysis of 58 peripheral blood specimens from patients with rectal and esophageal cancers demonstrated that circulating hybrid cells may be a novel, noninvasive biomarker with potential for monito...

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