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Arizona Oncology Announces Retirement of Kenneth Luk, MD

Brian Schade, Executive Director of Arizona Oncology, recently announced the retirement of Kenneth Luk, MD, a well-respected radiation oncologist in Phoenix for over 20 years. Dr. Luk is a Fellow of the American College of Radiology and Clinical Professor at the Midwestern University School of...

lung cancer

Experts Share Keys to a Successful Lung Screening Program

There are currently 172 computed tomography (CT)-based lung screening centers up and running in the United States, according to the Lung Cancer Alliance.1 In a presentation at the American Roentgen Ray Society (ARRS) 2014 Annual Meeting in San Diego, Reginald Munden, MD, DMD, MBA, and Ralph...

Cancer Center at Johns Hopkins Set to Expand With $65 Million Gift

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins has announced it will use a $65 million gift toward the construction of a new patient care building that will be named for the late Albert P. “Skip” ­Viragh, Jr. Mr. Viragh, a Maryland mutual fund investment leader and philanthropist,...

Demetrius H. Bagley, MD, Honored With AUA Lifetime Achievement Award

The American Urological Association (AUA) has presented ­Demetrius H. Bagley, MD, with its 2014 Lifetime Achievement Award for visionary leadership and education in ureteroscopy and minimally invasive surgical techniques for the upper urinary tract. Dr. Bagley is The Nathan Lewis Hatfield Professor ...

health-care policy

Unprecedented Release of Medicare Data Raises Concerns About Lack of Context: Statements From COA and ASTRO

In April, as part of the Obama administration’s work to make the U.S. health-care system more transparent, affordable, and accountable, the Centers for Medicare & Medicaid Services (CMS) released a vast amount of privacy-protected data on services and procedures provided to Medicare...

leukemia

Looking Ahead in Treating Chronic Lymphocytic Leukemia

It’s the dawn of a new era in the treatment of chronic lymphocytic leukemia (CLL), largely due to the development of agents targeting the BCR signaling pathway, according to John C. Byrd, MD, of The Ohio State University Comprehensive Cancer Center, Columbus. At the 19th Annual Conference of the...

issues in oncology
supportive care

NCCN Roundtable: When a Parent Has Cancer

Attendees at this year’s annual conference of the National Comprehensive Cancer Network (NCCN) not only got up to date on the Guidelines but left with a better understanding of how children deal with a parent’s cancer, and how oncology providers can best help. Panelists for the NCCN roundtable...

colorectal cancer

Surveillance After Colon Cancer Surgery: Too Much of a Good Thing?

Finding salvageable colon cancer recurrence is akin to finding a needle in a haystack, rendering routine patient surveillance of little value. But finding that needle offers an opportunity for treating recurrent disease early, which makes surveillance worthwhile. These were the opposing views...

Expert Point of View: George W. Sledge, Jr, MD

In his commentary on the ALTTO results, George W. Sledge, Jr, MD, Professor of Medicine and Director of the Division of Oncology at Stanford University, reminded attendees that the announcement of the first results for adjuvant trastuzumab, which occurred at the 2005 ASCO Annual Meeting, was “a...

Leading Cancer Researcher and Public Health-Care Expert, Eddie Reed, MD, Dies

In a 2010 interview, Eddie Reed, MD, a pioneer in the molecular pharmacology of DNA-damaging anticancer agents and the clinical development of paclitaxel for ovarian cancer, was asked what lay ahead. Before answering, Dr. Reed first acknowledged the esteemed mentors who gave him their most precious ...

David Craig, PharmD, Named to FDA Advisory Committee

Moffitt Cancer Center recently announced that Clinical Pharmacist David Craig, PharmD, has been appointed to the U.S. Food and Drug Administration’s Anesthetic and Analgesic Drug Products Advisory Committee. Dr. Craig specializes in pain medicine and palliative care. The Anesthetic and Analgesic...

Maurie Markman, MD, Named President of Medicine & Science Unit, Cancer Treatment Centers of America

Cancer Treatment Centers of America (CTCA) recently announced the appointment of Maurie Markman, MD, as President of the company’s Medicine & Science unit. He will be responsible for advancing the organization’s overall commitment to clinical excellence, innovation, safety, and patient...

colorectal cancer

Colon Cancer Prevention: It’s All About Mindset and Minute Details

I would like to congratulate Corley and his colleagues for their seminal work on the association between adenoma detection rate and risk of colorectal cancer, advanced colorectal cancer, and colorectal cancer mortality. The impact of their findings—reported in The New England Journal of Medicine1...

Paying It Forward: Breakthrough Prize Winners and Institutions Commit $3 Million in Support of Next Generation of Scientists

Following last year’s announcement of the first-ever Breakthrough Prizes, established by a group of Silicon Valley entrepreneurs to celebrate scientists and encourage careers in the field, the winners were frequently asked what they would do with their newfound prize money of $3 million each. Three ...

colorectal cancer

Colorectal Cancer Screening Poised for Change

New screening modalities and the customization of the screening population could soon change the way that screening for colorectal cancer is done. At Digestive Disease Week 2014, the largest gathering of gastrointestinal disease specialists in the world, researchers presented data suggesting that...

colorectal cancer

Combined With Chemotherapy, Cetuximab and Bevacizumab Found Comparable for First-Line Metastatic Colorectal Cancer Treatment

Call it a draw: Cetuximab (Erbitux), an EGFR inhibitor,  and bevacizumab (Avastin), a VEGF inhibitor, confer comparable benefits as first-line treatment with chemotherapy for metastatic colorectal cancer, according to the phase III Cancer and Leukemia Group B (CALGB)/Southwest Oncology Group (SWOG) ...

Advancing Immune Checkpoint Targeting in Cancer Treatment

James P. Allison, PhD, Professor and Chair of the Department of Immunology, Executive Director of the Moon Shots Immunotherapy Platform, and Deputy Directory of the David H. Koch Center for Applied Research of Genitourinary Cancers at The University of Texas MD Anderson Cancer Center, Houston, is...

ASTRO Names Three Radiation Oncologists as Recipients of Society’s 2014 Gold Medal

The American Society for Radiation Oncology (ASTRO) has announced the names of three recipients of the Society’s highest honor, the ASTRO Gold Medal. Mary K. Gospodarowicz, MD, FASTRO, Leonard L. ­Gunderson, MD, MS, FASTRO, and Nancy J. ­Tarbell, MD, FASTRO, will receive the ­ASTRO Gold Medal...

issues in oncology

'Physician Education Is Key' to Continued Advances in Geriatric Oncology

Several times during his lecture at the 2014 ASCO Annual Meeting, Stuart M. Lichtman, MD, FACP, FASCO, the recipient of the B.J. Kennedy Award for Scientific Excellence in Geriatric Oncology, emphasized, “Physician education is the key” to continued advances in geriatric oncology. He specified that ...

First Tang Prize for Biopharmaceutical Science Awarded to James P. Allison, PhD, and Tasuku Honjo, MD, PhD

The first Tang Prize for Biopharmaceutical Science has been awarded to James P. Allison, PhD, Chair of Immunology at The University of Texas MD Anderson Cancer Center and ­Tasuku Honjo, MD, PhD, of Japan’s Kyoto University for their research leading to cancer immunotherapy. “Both scholars’...

Andrew S. Kraft, MD, Named Director of University of Arizona Cancer Center

Andrew S. Kraft, MD, prostate cancer physician-scientist and cancer center administrator, has been named the Sydney E. Salmon Endowed Chair and Director of the University of Arizona Cancer Center and Associate Vice President for Oncology Programs for the University of Arizona Health Sciences...

Following ‘Fruitful’ Year of Collaboration, Advocacy, and Growth, Pediatric Hematology/Oncology Moves to Next Level

Finishing up a 2-year term as President of the American Society of Pediatric Hematology/Oncology (ASPHO), A. Kim Ritchey, MD, summarized ASPHO’s achievements in advocacy, education, and professional development in his State of the Society address at the ASPHO 27th Annual Meeting in Chicago. He also ...

2001 Young Investigator Award Recipient Pasi Jänne, MD, PhD,  Presents Research on Promising New Therapy for Treatment-Resistant NSCLC

At the 2014 ASCO Annual Meeting, Pasi Jänne, MD, PhD, Professor of Medicine at Dana-Farber Cancer Institute and Harvard Medical School, presented findings from a phase I study of AZD9291, a new mutant-selective EGFR tyrosine kinase inhibitor that offers a promising new treatment option for patients ...

2014 Breast Cancer Symposium to Focus on Collaborative Learning

ASCO’s educational symposia have historically provided attendees with a forum for learning and discussion, demonstrating ASCO’s commitment to promoting a network of global oncology expertise. The 2014 Breast Cancer Symposium, to be held in San Francisco from Thursday, September 4, to Saturday,...

James R. Downing, MD, Named CEO of St. Jude Children’s Research Hospital

St. Jude Children’s Research Hospital has announced the appointment of James R. Downing, MD, as its new Chief Executive Officer, effective July 15, 2014. Dr. Downing most recently has served as the Deputy Director, Executive Vice President and Scientific Director of the hospital.  Dr. Downing’s...

Raja Flores, MD, Named Chair of New Thoracic Surgery Department at Mount Sinai

The Mount Sinai Health System has announced the creation of a new academic Department of Thoracic Surgery at the Icahn School of Medicine at Mount Sinai in New York. Raja M. Flores, MD, will be the Founding Chairman of the Department for the Mount Sinai Health System.  Dr. Flores, the Steven and...

issues in oncology

Navigating Cancer in the Era of Personalized Medicine: Rev 2014 Explores Emerging Issues, Ideas for Action

Diagnosed with stage IV non–small cell lung cancer in 2011, Stephen Wright turned to patient support groups where he learned about the anaplastic lymphoma kinase (ALK) mutation and a new drug that targeted it, crizotinib (Xalkori). He asked—then insisted—that he be tested for the mutation. He found ...

lymphoma

‘R-Squared’ Regimen Delivers a Punch to Diffuse Large B-Cell Lymphoma Subtype

The combination of lenalidomide (Revlimid) and rituximab (Rituximab), dubbed the “R-squared” regimen, has gained attention lately, and ongoing trials are evaluating whether chemotherapy with R-CHOP (rituximab, cyclophosphamide, vincristine, doxorubicin, prednisone) can be improved by adding a...

prostate cancer

AR-V7 Predicts Resistance to Enzalutamide and Abiraterone in Men With Castration-Resistant Prostate Cancer

Androgen receptor (AR) splice variant 7 (V7) appears to be a new biomarker for response and disease progression in patients treated with enzalutamide (Xtandi) or abiraterone (Zytiga). The presence of AR-V7 in circulating tumor cells predicted resistance to both drugs in men with metastatic...

skin cancer

Long-Term Follow-up of Phase I Nivolumab Trial

In the longest follow-up to date of any programmed death (PD)-1 receptor inhibitor in previously treated advanced melanoma, one-third of patients are demonstrating durable responses to the investigational agent nivolumab, and in some cases, these persist following discontinuation of the drug,...

skin cancer

Ipilimumab Reduces Recurrences as Adjuvant Treatment of Melanoma

Ipilimumab (Yervoy) has transformed the treatment of metastatic melanoma, producing long-term responses in about 20% of patients. A phase III study has now evaluated its impact in the adjuvant setting, and the results are a bit less striking. Primary Endpoint The European Organisation for Research...

health-care policy

IOM Workshop Explores Growing Problems in Patient Access to Cancer Drugs

Cancer patients’ out-of-pocket costs are rising dramatically, and insurance premiums, cost sharing, and ancillary expenses can be devastating. Many people go bankrupt as a result of the high costs of health care. Drugs are among the most serious economic culprits. They grow more expensive every...

International Leader in Urology, Professor John Fitzpatrick, Dies

His life was gentle, and the elements So mixed in him that Nature might stand up And say to all the world, “This was a man!” —William Shakespeare   I have too many positive memories of John to regale you with here,” said Roger Kirby, MD, in a tribute to his close friend and colleague, John Michael...

David C. Beyer, MD, FASTRO, Named President-Elect, ASTRO Board of Directors

Members of the American Society for Radiation Oncology ­(ASTRO) have elected David C. Beyer, MD, ­FASTRO, President-Elect of the ASTRO Board of Directors. Dr. Beyer will begin his term at the Annual Business Meeting in September during ASTRO’s 56th Annual Meeting in San Francisco. Colleen A.F....

global cancer care

From Ireland to America and Back, Patrick G. Johnston, MD, PhD, Thrives on Bringing Research Findings to Clinical Practice

Patrick G. Johnston, MD, PhD, FMedSci, Professor of Oncology and President and Vice-Chancellor of Queen’s University Belfast, grew up in Derry, a city in Northern Ireland. Derry is distinct in being Ireland’s only remaining fully intact walled city, considered one of the finest examples of a walled ...

issues in oncology

ASCO’s 50th Anniversary: Past Presidents Recall Top Issues During Their Terms

In a series of articles on the American Society of Clinical Oncology’s CancerProgress.Net website, past ASCO presidents are sharing their recollections of the major issues during their terms. Emil J Freireich, MD, FASCO, (1980–1981), remembered that during his presidency, ASCO began the process of...

issues in oncology
cost of care

Stakeholders Are Uniting Around Value in Cancer Care

Judging from its visibility at the 2014 ASCO Annual Meeting, the concept of “value” in cancer care has reached critical mass. “ASCO is leading this difficult discussion on value in cancer care. This had to happen,” said ­Clifford A. Hudis, MD, FACP, Immediate Past President of ASCO and Chief of the ...

SIDEBAR: Long-term International Fellowship (LIFe) Award

The Long-term International Fellowship (LIFe) provides early-career oncologists in developing nations the support and resources needed to advance their training by deepening their relationship with a U.S. or Canadian colleague and his or her institution. The fellowship was first awarded to a single ...

issues in oncology

Take-Home Messages From ASCO's Immediate Past President

The ASCO Post recently spoke with ASCO Immediate Past President Clifford A. Hudis, MD, FACP, about his term as ASCO President. Dr. Hudis discussed his thoughts on ASCO today and shared his perspective on a number of important issues in oncology, including value in cancer care, big data, and more....

Expert Point of View: Howard A. Fine, MD and Martin J. van den Bent, MD

Session moderator Howard A. Fine, MD, the Anne Murnick Cogan and David H. Cogan Professor of Oncology and Director of the Brain Tumor Center at New York University Cancer Institute, shared his enthusiasm over the findings of the RTOG 9802 study. “I don’t know of any other tumor type where the...

prostate cancer

‘Reasonable’ to Advise Men Who Have Had Vasectomies That They Have a Small Increased Risk for Lethal Prostate Cancers

Long-term results from the Health Professionals Follow-up Health Study have shown a 20% increased risk of advanced prostate cancer and a 19% increased risk of lethal prostate cancer among men who had vasectomies.1 According to the study’s lead author, Mohummad Minhaj Siddiqui, MD, it is...

multiple myeloma
issues in oncology
survivorship

Cancer Survivor and Patient Advocate Michael S. Katz, MBA,  Has Helped Alter the Standard of Care for Myeloma Survivors

Michael S. Katz, MBA, has lived longer than any of his doctors thought he would. A two-time cancer survivor, Mr. Katz was diagnosed, first with multiple myeloma in 1990 and then with colorectal cancer in 2008, and has spent the past 2 decades tirelessly advocating for patients with cancer. The...

Don Shula Foundation Donates $1.5 Million to Moffitt Cancer Center

The Don Shula Foundation is donating $1.5 million to Moffitt Cancer Center to establish The Don Shula Breast Cancer Research Fund (The Shula Fund). Scientists at Moffitt will use The Shula Fund to support cutting-edge research projects that will generate new treatment and prevention strategies for...

V. Craig Jordan, PhD, to Join MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center has announced that V. Craig Jordan, PhD, will join the institution in October 2014 as a Professor in Breast Medical Oncology and Molecular and Cellular Oncology. Dr. Jordan will focus on the new biology of estrogen-induced cell death with the goal...

head and neck cancer

Michael Douglas Shares His Experience With Stage IV Oropharyngeal Cancer

Academy Award winning actor and producer Michael Douglas was the guest of honor at the opening day of the International Federation of Head and Neck Oncologic Societies (IFHNOS) 5th World Congress on July 27 in New York (see page 22 for more on the World Congress). He came not to plug the release of ...

Book Excerpt: Family

I've witnessed incredible courage and zest for life among so many patients from so many walks of life—individuals committed to helping others in spite of their own adversity. Forty years ago, when survival for patients with multiple myeloma was a matter of months, I knew that every person I sat...

solid tumors

Oncologists Tell Inspiring Stories of What It’s  Like to Treat Cancer in The Big Casino

Title: The Big Casino: America’s Best Cancer Doctors Share Their Most Powerful StoriesEditors: Stan Winokur, MD, and Vincent CoppolaPublishing Platform: CreateSpacePublication date: May 2014Price: $9.99; Paperback, 160 pages   In May, Stan Winokur, MD, and co-editor Vincent Coppola, published The...

Patrick Soon-Shiong, MD, to Lead Providence Health Cancer Services and Bioinformatics

Providence Health & Services has announced that Patrick Soon-Shiong, MD, will serve as the health-care system’s new Global Director for Cancer Services and Bioinformatics. In this role, Dr. Soon-Shiong will work closely with oncology clinicians and researchers across the five-state Providence...

palliative care

Using Patient-Reported Outcome Measures in Palliative Care Clinical Practice

Incorporating patient-reported outcomes into the palliative care clinical setting can improve patients’ symptom management, quality of life, and overall communication with their oncologists, according to Ethan Basch, MD. Dr. Basch is Director of the Cancer Outcomes Research Program and Associate...

Facing Cancer Together

David sits at his desk, tapping angrily. He’s tired of his abusive, ignorant boss, the VP for regional sales. The man’s sales targets are absurdly high, he’s impossible to reach on the phone, his “motivational” speeches evoke the stress of Glengarry Glen Ross, and even his fake all-light-brown hair ...

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