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Bert Vogelstein, MD, and Irving L. Weissman, MD, Recognized for Revolutionizing Cancer Research

Two scientists, whose discoveries in stem cell and cancer cell biology have led to innovative advances in fields ranging from oncology and immunology to cancer genomics and regenerative medicine, will receive the 2019 Albany Medical Center Prize in Medicine and Biomedical Research. Bert Vogelstein, ...

cns cancers
lymphoma

Primary Central Nervous System Lymphoma: Striving for a Curative Therapy

Primary central nervous system (CNS) lymphoma is a rare type of non-Hodgkin lymphoma in which standards of care have not been well established. In light of recent insights into its pathophysiology and the emergence of novel approaches, The ASCO Post asked Tracy T. Batchelor, MD, a specialist in...

David I. Sternberg, MD, Joins Karmanos Cancer Institute

The Barbara Ann Karmanos Cancer Institute has announced that thoracic surgeon David I. Sternberg, MD, has joined its medical team. Board-certified in general and cardiothoracic surgery, and specialized in minimally invasive chest surgery, Dr. Sternberg will serve on Karmanos’ Thoracic Oncology...

$1 Million Gift for Epithelioid Hemangioendothelioma Research

The Epithelioid Hemangioendothelioma (EHE) Foundation and Cleveland Clinic recently received a $1 million gift from the Margie and Robert E. Petersen Foundation. The money will support EHE research conducted by Brian Rubin, MD, PhD, Chair of the Robert J. Tomsich Pathology & Laboratory Medicine ...

issues in oncology

How Patient Advocacy Is Integral to High-Quality Oncology Care

Karen M. Winkfield, MD, PhD, has made patient advocacy—with a specific emphasis on health equity and access to high-quality care—front and center of her oncology practice since she completed her residency at the Harvard Radiation Oncology Program in Boston, where she noticed that most of the...

integrative oncology

Light Intervention for Cancer-Related Fatigue, Depression, and Sleep Disturbance

GUEST EDITOR  Integrative Oncology is guest edited by Jun J. Mao, MD, MSCE, Laurance S. Rockefeller Chair in Integrative Medicine and Chief of Integrative Medicine Service at Memorial Sloan Kettering Cancer Center, New York. Cancer and its treatments are associated with severe fatigue, depression, ...

head and neck cancer

Maura L. Gillison, MD, PhD, Pioneer in HPV-Related Head and Neck Cancer, Has Often Changed Lanes in Her Career

When The ASCO Post asked physician-scientist Maura L. Gillison, MD, PhD, where she was from, she answered, “North America.” Actually, she was born in Canada, but her father worked for a large international company, so the family moved regularly through Canada, the United States, and Mexico. “I...

breast cancer

Tumor Size and Grade Matter, and Ovarian Ablation by Chemotherapy May Explain Subgroup Anomaly in TAILORx

At the 2019 ASCO Annual Meeting, and simultaneously in The New England Journal of Medicine, we heard the third paper reporting results from TAILORx.1,2 The first, in 2015,3 indicated that women with node-negative breast cancers with Oncotype DX recurrence scores less than 11 did extremely well...

supportive care
symptom management

Virtual Reality May Improve Pain, Vision, Functioning in Patients With Cancer

Virtual reality can be used to improve functioning in patients with cancer, according to David Rhew, MD, Chief Medical Officer, Vice President and General Manager of Enterprise Healthcare, Samsung Electronics America. Research has shown that this technology can decrease pain and improve vision, as...

issues in oncology
geriatric oncology

Polypharmacy Associated With Functional Decline in Older Patients With Advanced Cancer

Polypharmacy (ie, the concurrent use of eight or more medications) and potentially inappropriate medications may be associated with functional impairment in older adults with advanced cancer, according to research presented by ­Mostafa Mohamed, MBBCh, at the Multinational Association of Supportive...

immunotherapy

What Causes Liver Injury During Treatment With Pembrolizumab

Immunotherapy as a treatment for advanced solid cancers has rapidly evolved over the past decade—often yielding remarkable results. However, its use has also given way to new adverse effects, including drug-induced gastrointestinal and liver toxicities. “Checkpoint inhibitors are a game changer...

Cancer Research Institute Names New ‘STARs’ of Cancer Immunotherapy Research

The Cancer Research Institute (CRI), a nonprofit organization dedicated to the discovery and development of immunotherapies for all types of cancer, recently unveiled the inaugural cohort of scientists chosen for the CRI Lloyd J. Old STAR Program (Scientists Taking Risks). Each “STAR” will receive...

ASTRO Elects Four New Officers to Board of Directors

The members of the American Society for Radiation Oncology (ASTRO) have elected four new officers to ASTRO’s Board of Directors. Laura Dawson, MD, FASTRO, will begin her term as President-Elect in September during ASTRO’s 61st Annual Meeting in Chicago. Neha Vapiwala, MD, was elected as ASTRO’s new ...

George J. Bosl, MD, FASCO, MACP, Named Memorial Sloan Kettering’s First Ombudsperson

In July, George J. Bosl, MD, FASCO, MACP, became Memorial Sloan Kettering’s (MSK) first ombudsperson, working closely with staff to provide confidential, independent guidance on complex and evolving issues, particularly related to conflicts of interest. The role of ombudsperson is a result of the...

V. Craig Jordan, CMG, OBE, PhD, DSc, Honored for Accomplishments in Women’s Health

The Companion of the Most Distinguished order of St. Michael and St. George (CMG) is generally reserved for ambassadors and leaders of the United Kingdom’s defense and security services. Only 1, 750 appointees are permitted. This year, the Head of M16, the Secret Intelligence Service, was in the...

immunotherapy

What Causes Liver Injury During Treatment With Pembrolizumab

Immunotherapy as a treatment for advanced solid cancers has rapidly evolved over the past decade—often yielding remarkable results. However, its use has also given way to new adverse effects, including drug-induced gastrointestinal and liver toxicities. “Checkpoint inhibitors are a game changer...

An Early Decision to Become an Oncologist

GUEST EDITOR Dr. Abraham is the Director of the Breast Oncology Program at Taussig Cancer Institute, and Professor of Medicine, Lerner College of Medicine, Cleveland Clinic.   For this installment of the Living a Full Life series, Guest Editor Jame Abraham, MD, FACP, spoke with Gilberto de Lima...

West Virginia University Cancer Institute Welcomes Eight New Doctors

The West Virginia University (WVU) Cancer Institute continues to expand its list of specialists with the addition of eight new doctors. Sonikpreet Aulakh, MD, will join WVU Medicine from Mayo Clinic Florida, where she is completing a hematology oncology fellowship. She completed her medical degree...

solid tumors
head and neck cancer

Remembering Michael D. Becker

The staff of The ASCO Post were sad to learn of the passing of Michael D. Becker on July 9, 2019. When Michael was diagnosed with human papillomavirus (HPV)-related oropharyngeal cancer in 2015, he made the decision to go public with his diagnosis to raise awareness of the importance of having...

Joseph A. Sparano, MD, to Receive William L. McGuire Memorial Lecture Award

Joseph A. Sparano, MD, will receive the William L. McGuire Memorial Lecture Award at the 2019 San Antonio Breast Cancer Symposium (SABCS), to be held December 10–14. The McGuire Award was established in 1992 to honor William L. McGuire, MD, who, along with Charles A. Coltman, MD, founded the SABCS...

The Radium Era: 1916–1945

The text and photograph on this page are excerpted from a four-volume series of books titled Oncology: Tumors & Treatment, A Photographic History, by Stanley B. Burns, MD, FACS, and Elizabeth A. Burns. The photo below is from the volume titled “The Radium Era: 1916–1945.” The photograph appears ...

integrative oncology

Echinacea

The ASCO Post’s Integrative Oncology series is intended to facilitate the availability of evidence-based information on integrative and complementary therapies sometimes used by patients with cancer. In this installment, Yen Nien Hou, PharmD, DipIOM, LAc, explores the potential health benefits of...

The Obesity Epidemic From a Neuroscience Perspective

Since the 1970s, there has been an alarming increase in obesity. According to the latest data from the Centers for Disease Control and Prevention (CDC), about 70% of Americans are either overweight or obese. Excess body weight is linked to numerous diseases, including more than 14 types of cancers. ...

Out of the Mouths of Babes: A Physician Discusses Her Cancer Diagnosis With Her Two Young Children

  In medical school, I learned a five-step model on how to deliver bad news to a patient. I still fall back on this method, time and again, in my primary care clinic; I have even used it when giving really tough feedback to a learner who is struggling in some aspect of performance. But I honestly...

Institute of Cancer Research Annual Science and Medical Image Competition

Each year, investigators from the Institute of Cancer Research (ICR), London, and the Royal Marsden NHS Trust collaborate to showcase images from their research to highlight the often unseen beauty of science. Maxine Lam, PhD,  a postdoctoral training fellow at ICR captured an image of a cancer...

hematologic malignancies

ASH Honors Richard Aster, MD, With the Wallace H. Coulter Award for Lifetime Achievement in Hematology

The American Society of Hematology (ASH) will recognize Richard Aster, MD, of the Medical College of Wisconsin and Versiti Blood Center of Wisconsin in Milwaukee with the 2019 Wallace H. Coulter Award for Lifetime Achievement in Hematology. Dr. Aster will be honored for his significant...

issues in oncology
health-care policy

Looking at the Impact of State Policies on Access to High-Quality Care

The state of Washington is adding a public option to its health insurance marketplace; Massachusetts, Connecticut, and others have passed laws requiring that payers cover fertility preservation procedures for patients with cancer. Many states are seeking to expand Medicaid eligibility, and some, in ...

breast cancer
genomics/genetics

How Laura J. van ’t Veer, PhD, Became an Expert in Genetic Testing for Breast Cancer

Breast cancer researcher and innovator Laura J. van ’t Veer, PhD, was born and reared in Amsterdam in 1957. “During high school, I had a wonderful biology teacher who was going through his own biology studies at the University of Amsterdam, and he was bringing that university-level education into...

Leading City of Hope Hematologists Appointed to New Positions

Larry Kwak, MD, PhD, has been appointed the Deputy Director of City of Hope’s Hematologic Malignancies and Stem Cell Transplantation Institute. Tanya Siddiqi, MD, Associate Clinical Professor in City of Hope’s Department of Hematology & Hematopoietic Cell Transplantation, has been appointed...

AACR Announces 2019 Class of Fellows of the AACR Academy

The American Association for Cancer Research (AACR) recently announced its newly elected class of Fellows of the AACR Academy. The mission of the AACR Academy is to recognize and honor distinguished scientists whose scientific contributions have propelled innovation and progress against cancer. The ...

survivorship

Preserving Sexuality and Restoring Sexual Function in Male and Female Cancer Survivors

Intimacy changes after a cancer diagnosis. Both male and female survivors can experience significant sexual dysfunction, pain with sex, loss of desire, and a slew of other clinical and psychological sequelae. To make matter worse, sexual function is often not discussed by patients and their...

symptom management
immunotherapy

What Causes Liver Injury During Treatment With Pembrolizumab?

Immunotherapy as a treatment for advanced solid cancers has rapidly evolved over the past decade—often yielding remarkable results. However, its use has also given way to new adverse effects, including drug-induced gastrointestinal and liver toxicities. “Checkpoint inhibitors are a...

supportive care
palliative care
pain management

How an Innovative AI-Based Smartphone Application Is Addressing Patients’ Palliative Care Needs

GUEST EDITOR Addressing the evolving needs of cancer survivors at various stages of their illness and care, Palliative Care in Oncology is guest edited by Jamie H. Von Roenn, MD, FASCO. Dr. Von Roenn is ASCO’s Vice President of Education, Science, and Professional Development.   During the 2019...

immunotherapy

What Causes Liver Injury During Treatment With Pembrolizumab?

Immunotherapy as a treatment for advanced solid cancers has rapidly evolved over the past decade—often yielding remarkable results. However, its use has also given way to new adverse effects, including drug-induced gastrointestinal and liver toxicities. “Checkpoint inhibitors are a game changer...

Director of the FDA’s Oncology Center of Excellence Discusses Expanded Access, Accelerated Drug Approvals in Latest ASCO in Action Podcast

THE DIRECTOR OF the U.S. Food and Drug Administration’s (FDA) Oncology Center of Excellence (OCE), Richard Pazdur, MD, joins ASCO Chief Executive Officer Clifford A. Hudis, MD, FACP, FASCO, in the latest ASCO in Action Podcast to discuss the FDA’s new program to make it easier for physicians to...

issues in oncology

Parental Treatment Refusals: What Your Responsibilities Are When Mom and Dad Decline Cancer Treatment for a Child

In April 2019, a 3-year-old boy, Noah McAdams, missed the third round of chemotherapy for his acute lymphoblastic leukemia. His parents wanted instead to focus on alternative remedies of cannabidiol oil, alkaline water, mushroom tea, and herbal extracts. The sheriff was summoned; Noah’s parents...

Florida Cancer Specialists Welcomes Barry S. Berman, MD

FLORIDA CANCER SPECIALISTS & Research Institute (FCS) recently announced that medical oncologist and hematologist Barry S. Berman, MD, has joined the statewide practice and will be seeing patients in two offices: West Palm Beach and Wellington North.  Board-certified in medical oncology,...

issues in oncology

Is It Time to Reevaluate the P Value in Biomedical Research?

Developed in 1925 by British statistician Sir Ronald Fisher, the P value is a measure that is ever-present in abstracts and studies, a small statistical tool that has enormous power to aid research being published in the literature or support drug approval. Over the past several years, however, a...

William Cance, MD, Named Interim Director of University of Arizona Cancer Center

William Cance, MD, Deputy Director of the University of Arizona (UA) Cancer Center in Phoenix has been appointed Interim Director of the UA Cancer Center. Dr. Cance, who joined the UA in October 2016, is also Professor in the Departments of Interdisciplinary Oncology, Pharmacology and Toxicology,...

New Members Join Stand Up To Cancer’s Advisory Committee

Stand Up To Cancer (SU2C), with its scientific partner, the American Association for Cancer Research (AACR), announced two new members of the SU2C Scientific Advisory Committee: John D. Carpten, PhD, Director of the Institute of Translational Genomics at the Keck School of Medicine of the...

issues in oncology

No Man Is an Island: Reflections From an ASCO IDEA Recipient

IT WAS a chilly Chicago morning, and I was sitting at the lobby of my hotel when I saw a smiling gentleman cheerfully waving at me from his car. It was Lawrence H. Einhorn, MD, picking me up for our drive to Indiana. I was one of the recipients of the ASCO International Development and Education...

Emergency Medicine Doctor Reflects on 5 Decades of Career Experiences

BOOKMARK Title: Patient Care: Death and Life in the Emergency RoomAuthor: Paul Seward, MDPublisher: CatapultPublication Date: July 2018Price: $22.95, hardcover, 240 page The history of emergency medicine residency training is interlaced with the impetus for specialty status in emergency medicine,...

A Compassionate Family Doctor Sparked an Interest in Medicine for Lori Pierce, MD, FASTRO, FASCO

GUEST EDITOR Jame Abraham, MD, FACP Dr. Abraham is the Director of the Breast Oncology Program at Taussig Cancer Institute, and Professor of Medicine, Lerner College of Medicine, Cleveland Clinic. For this installment of the Living a Full Life series of articles, guest editor Jame Abraham, MD,...

Laughter in Oncology Is More Common Than You Think

The ASCO Post is pleased to reproduce installments of the Art of Oncology as published previously in the Journal of Clinical Oncology. These articles focus on the experience of suffering from cancer or of caring for people diagnosed with cancer, and they include narratives, topical essays,...

Society of Nuclear Medicine and Molecular Imaging Elects New Officers for 2019–2020

The society of nuclear medicine and Molecular Imaging (SNMMI) announced a new slate of officers during its 2019 Annual Meeting, in Anahaeim, California. Alan B. Packard, PhD, and Richard L. Wahl, MD, were elected the 2019–2020 President-Elect and Vice President-Elect, respectively. Alan B. Packard, ...

colorectal cancer
issues in oncology

Rates of Colorectal Cancer Diagnosis in Adults Younger Than Age 50

A new study published by Virostko et al in Cancer found that the proportion of adults diagnosed with colorectal cancer under age 50 in the United States has continued to increase over the past decade, and younger adults are diagnosed with more advanced disease. To determine recent trends in...

Long-Term Results From the National Lung Screening Trial

This week, we discuss long-term results from an extended analysis of the National Lung Screening Trial, and Dr. James Mulshine of Rush University offers his thoughts on these findings. We also review a report on radioactive iodine treatment for hyperthyroidism and long-term risk of death from solid ...

breast cancer

Role of Regulatory T Cells in Predicting Breast Cancer Relapse

Blood and intratumoral regulatory T-cell activity may one day provide a method for predicting breast cancer relapse, according to findings published by Wang et al in Nature Immunology. “This is the first success linking a solid tumor with blood biomarkers—an indicator of whether a...

solid tumors

Subtypes of Pancreatic Neuroendocrine Tumors and Effect on Disease Recurrence

Researchers have discovered two distinct subtypes of pancreatic neuroendocrine tumors (pNETs) associated with different risks of recurrence following surgical treatment. The finding could yield predictive tests while focusing vigilant follow-up monitoring on patients with pNETs that have a higher...

A Pioneering Surgeon Who Opened Doors for Others, LaSalle D. Leffall, Jr, MD, Dies at 89

Lifting himself from the barriers of the segregated South, LaSalle D. Leffall, Jr, MD, would become a nationally regarded oncologic surgeon who opened doors for other in the medical profession. His career was distinguished by “firsts,” such as the first African America President of both the...

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