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SSO 2016: Federal 'Moonshot' Fight Against Cancer Means More Resources for Surgical Oncology Professionals

The 69th Society of Surgical Oncology (SSO) Annual Cancer Symposium, being held March 2–5 in Boston, will include featured lecturers with ties to the recently announced White House “moonshot” initiative to cure cancer—a proposed $1 billion in spending on cancer research over ...

prostate cancer

Light Reflectance Technique May Improve Ability to Remove Prostate Cancer During Surgery

Researchers at UT Southwestern Medical Center have determined that light reflectance spectroscopy can differentiate between malignant and benign prostate tissue with 85% accuracy, a finding that may lead to real-time tissue analysis during prostate cancer surgery. These findings were reported...

breast cancer

Breast Reconstruction Using Abdominal Tissue: Differences in Outcome With Four Techniques

In women undergoing breast reconstruction using autologous tissue, newer muscle-sparing abdominal flaps can reduce complications while improving some aspects of quality of life, according to a study by Macadem et al in Plastic and Reconstructive Surgery. Comparison of four types of abdominal flaps ...

lung cancer
global cancer care

Study Finds 36% Increase in Number of Male Smokers in India Over 17 Years

The number of men smoking tobacco in India rose by more than one third to 108 million between 1998 and 2015, according to a new study published in the journal BMJ Global Health. The study also found that cigarettes were replacing the traditional bidi, a small, inexpensive Indian cigarette,...

cns cancers

Malignant Brain Tumors Most Common Cause of Cancer Deaths in Adolescents and Young Adults

A new report published by Ostrom et al in the journal Neuro-Oncology sponsored by the American Brain Tumor Association (ABTA) found that malignant brain tumors are the most common cause of cancer-related deaths in adolescents and young adults aged 15 to 39, and the most common cancer occurring...

breast cancer

Steven Shak, MD, on Breast Cancer–Specific Mortality

Steven Shak, MD, of Genomic Health, discusses mortality among patients with early-stage hormone receptor–positive invasive breast cancer in the SEER database who were treated based on the 21-gene Recurrence Score results (Abstract 176).

issues in oncology

Ethan Basch, MD, on Assessing Quality: Patient-Reported Data

Ethan Basch, MD, of the University of North Carolina at Chapel Hill, summarizes a session he chaired on the burgeoning use of patient-reported outcomes and wearable sensors in clinical practice and research.

issues in oncology

Monika K. Krzyzanowska, MD, MPH, on Patient-Centered Outcomes Research: Expert Perspective

Monika K. Krzyzanowska, MD, of Princess Margaret Cancer Centre, summarizes a session that she co-chaired on this key topic.

issues in oncology

Randall F. Holcombe, MD, on Delivering Quality Care in a Large, Urban Institution

Randall F. Holcombe, MD, of the Icahn Mount Sinai School of Medicine, discusses the challenges of delivering quality care in an academic setting at a large hospital.

issues in oncology

Lee N. Newcomer, MD, on Assessing Quality: Payer Perspective

Lee N. Newcomer, MD, of the UnitedHealth Group, gives his perspective on how to assess quality in the age of precision medicine.

health-care policy

Robert Miller, MD: CancerLinQ Update

Robert Miller, MD, ASCO’S Vice President of Quality and Guidelines, discusses CancerLinQ, the “big data” technology platform, and implementation of a rapid learning system for oncology based on Institute of Medicine principles.

issues in oncology

Allison Kurian, MD, on Assessing Quality in the Age of Precision Medicine

Allison Kurian, MD, of Stanford University School of Medicine, discusses pressing questions about the clinical utility and value of extended genomic testing and other forms of precision medicine.

issues in oncology

Joseph O. Jacobson, MD, on Improving Cancer Care: What Works, What Doesn’t, and Why

Joseph O. Jacobson, MD, of the Dana-Farber Cancer Institute, discusses a session he co-chaired on the thorny questions of how best to improve cancer care.

issues in oncology

Sandra L. Wong, MD's, Oral Abstract Discussion: Expert Perspective

Sandra L. Wong, MD, of the Dartmouth-Hitchcock Medical Center, summarizes three abstracts for which she was the discussant. The topics were rates of surgical site infections, an online resource for hospital cancer surgery volumes, and barriers to oncology appointments at comprehensive cancer...

survivorship

Lawrence N. Shulman, MD, on Survival as a Measure of Quality and Advances in Therapy

Lawrence N. Shulman, MD, of the University of Pennsylvania, discusses his paper, which explores lessons learned from analyses of the National Cancer Data Base. (Abstract 173)

issues in oncology

Patricia A. Ganz, MD, on Improving Quality and Value in Cancer Care

Patricia A. Ganz, MD, of the University of California at Los Angeles, the 2016 winner of the Joseph V. Simone Award, summarizes her “Lecture for Excellence in Quality and Safety in the Care of Patients With Cancer.”

cost of care

Sarina Isenberg, PhD Candidate, on Better Care at a Better Cost

Sarina Isenberg, PhD Candidate, of the Johns Hopkins Bloomberg School of Public Health, discusses the cost savings of a comprehensive hospital-based palliative care program. (Abstract 2)

issues in oncology

Joseph V. Simone, MD, on Safety and Quality in Cancer Care: The Big Picture

Joseph V. Simone, MD, of the Simone Consulting Company, reflects on the prospects for the future of safety and quality.

issues in oncology

Craig Earle, MD, on The Science of Quality

Craig Earle, MD, of Canada’s Institute for Clinical Evaluative Sciences, summarizes abstracts discussed in a ticketed session that he co-chaired on this key topic. (Abstracts 173, 174, 175)

issues in oncology

Kerin B. Adelson, MD, on Improving Cancer Staging

Kerin B. Adelson, MD, of the Yale Cancer Center, discusses an electronic decision support tool to capture staging data. This information allows automated reports for clinical trial screening, outcomes analysis, quality comparisons, and reporting. (Abstract 151)

palliative care
cost of care

Kerin B. Adelson, MD, on Improving End-of-Life Planning and Reducing Futile Care

Kerin B. Adelson, MD, of the Yale Cancer Center, discusses the major healthcare cost drivers at the end of life—aggressive treatments, emergency room visits, and futile care—and strategies for improving value. (Abstract 3)

issues in oncology

Dawn L. Hershman, MD, on Improving Quality and Safety With Multidisciplinary Teams

Dawn L. Hershman, MD, of Columbia University Medical Center, summarizes a joint ASCO/NCI session on this important topic, including the challenges and solutions.

supportive care

2016 Quality Care Symposium: New Triage System Decreases Emergency Room Visits by Oncology Patients in Florida

A quality improvement initiative to reduce patients’ reliance on emergency room (ER) visits to treat cancer treatment side effects has shown to be highly effective, according to early findings from a new study. The strategy, involving a telephone triage service coupled with patient education, ...

cost of care

2016 Quality Care Symposium: Online Tool Improves Access to Information on Cancer Treatment Costs

To facilitate doctor/patient conversations about costs of cancer care, researchers developed and piloted an online tool for oncologists. The innovative resource lists prices for the 50 most commonly prescribed cancer treatment regimens. A survey of the pilot users at four clinics in Washington...

breast cancer

2016 Quality Care Symposium: Study Suggests Many Women With Early Breast Cancer Receive Unnecessary Imaging Tests

A new study suggests that up to 60% of the computed tomography (CT) scans, bone scans, and positron-emission tomography (PET) scans performed for more than 29,000 Michigan women diagnosed with early breast cancer between 2008 and 2014 could not be medically justified based on retrospective record...

lung cancer
gastrointestinal cancer

FDA Approves Everolimus for Neuroendocrine Tumors of Gastrointestinal or Lung Origin

The U.S. Food and Drug Administration today approved everolimus (Afinitor) for the treatment of adult patients with progressive, well-differentiated nonfunctional neuroendocrine tumors of gastrointestinal or lung origin with unresectable, locally advanced, or metastatic disease. ...

lymphoma

FDA Approves Obinutuzumab in Follicular Lymphoma

The U.S. Food and Drug Administration (FDA) today approved obinutuzumab (Gazyva) for use in combination with bendamustine (Bendeka, Treanda) followed by obinutuzumab monotherapy for the treatment of patients with follicular lymphoma who relapsed after, or are refractory to, a rituximab...

issues in oncology

Cancer Statistics for African Americans, 2016

A new report outlines substantial progress in reducing the mortality gap between blacks and whites for some cancers, while the gap has widened or remained level for two leading cancers: breast cancer in women and colorectal cancer in men. The findings are included in Cancer Statistics for African...

lymphoma

Weight and Height During Adolescence May Impact Future Risk of Developing Non-Hodgkin Lymphoma

A new analysis indicates that higher body weight and taller stature during adolescence increase the risk of developing Non-Hodgkin lymphoma (NHL). The findings were published by Leiba et al in Cancer. Rates of NHL have increased worldwide, and research suggests that rising rates of obesity may be...

ASCO Commends Confirmation of Robert M. Califf, MD, as FDA Commissioner

“We commend the U.S. Senate for confirming Robert M. Califf, MD, as Commissioner of the Food and Drug Administration (FDA). Dr. Califf brings extraordinary expertise and vision to this position and we are confident that his appointment will positively impact cancer care. “Dr. Califf's...

survivorship

Eye Movement Affected in Some Former Childhood Cancer Patients

A study from Lund University in Sweden has shown that commonly used chemotherapy toxins impair the eyesight in childhood cancer survivors in a way that indicates an impact on the central nervous system. The results were published by Einarsson et al in PLOS One. It was not the former patients' ...

hematologic malignancies

First-in-Class Drug ONC201 Shows Potential for Some Blood Cancers

ONC201, an investigational anticancer drug that triggers cell death in various tumor types, may have clinical potential for some blood cancers including mantle cell lymphoma and acute myeloid leukemia (AML), according to a recent clinical study. A research team led by Michael Andreeff, MD, PhD,...

pancreatic cancer

Chemotherapy Preferable to Radiotherapy to Reduce Distant Pancreatic Cancer Recurrences

Patients who received chemotherapy after surgical resection of pancreatic cancer have fewer distant disease recurrences and longer overall survival than those who also had adjuvant chemoradiation therapy. While a course of radiotherapy in addition to chemotherapy and a cancer operation reduced the...

head and neck cancer

2016 Head and Neck Cancer Symposium: Induction Chemotherapy Does Not Predict Survival Advantage Over Concurrent Chemoradiation

Head and neck cancer patients who receive induction chemotherapy rather than the standard treatment of concurrent chemoradiation do not benefit from increased survival rates and are less likely to receive a full course of radiation, according to research presented by Stokes et al at the 2016...

issues in oncology
gynecologic cancers
head and neck cancer

100% of NCI-Designated Cancer Centers Endorse the Promotion of the HPV Vaccination for Cancer Prevention

All National Cancer Institute (NCI)-designated cancer centers have united to support human papillomavirus (HPV) vaccination (see below). A team of HPV experts drafted a consensus statement that advises widespread use of HPV vaccines to prevent cancer. HPV causes cancer of the cervix, anus, and...

Junior Investigators Win Awards for Pilot Projects

The results of the Fox Chase Cancer Center’s American Cancer Society Institutional Research Grant (IRG) Pilot Project Competition for Junior Investigators that was held in December 2015 have been announced. The competition was open to eligible junior faculty at Fox Chase Cancer Center or Temple...

integrative oncology

Mistletoe

The use of dietary supplements by patients with cancer has increased significantly over the past 20 years despite insufficient evidence of safety and effectiveness. Finding reliable sources of information about dietary supplements can be daunting. Patients typically rely on family, friends, and...

Mary-Claire King, PhD, Awarded 2016 Szent-Györgyi Prize for Progress in Cancer Research

The National Foundation for Cancer Research has announced that Mary-Claire King, PhD, Professor of Genome Sciences and Medicine (Medical Genetics) at the University of Washington, Seattle, has been awarded the 2016 Szent-Györgyi Prize for Progress in Cancer ­Research. The National Foundation for...

breast cancer

FDA Approves Palbociclib in Combination With Fulvestrant in Hormone Receptor–Positive, HER2-Negative Advanced or Metastatic Breast Cancer

On February 19, 2016, the U.S. Food and Drug Administration approved palbociclib (Ibrance) in combination with fulvestrant for the treatment of women with hormone receptor–positive, human epidermal growth factor receptor 2 (HER2)–negative advanced or metastatic breast cancer with...

head and neck cancer

2016 Head and Neck Cancer Symposium: Chemoradiation May Increase Survival for a Subset of Elderly Head and Neck Cancer Patients

The addition of chemotherapy to radiation therapy improves survival rates among a subset of elderly head and neck cancer patients, specifically those aged 71 to 79 with low comorbidity scores and advanced disease stage, according to research presented by Amini et al at the 2016 Multidisciplinary...

head and neck cancer

2016 Head and Neck Cancer Symposium: Most Recurrences of HPV-Positive Oropharyngeal Cancer Can Be Found Within 6 Months

For patients treated with definitive radiation therapy for oropharyngeal cancer caused by human papillomavirus (HPV), the majority of recurrences can be detected by post-treatment imaging at 3 months and physical exams during the 6 months following treatment, according to research presented by...

Jaclyn Biegel, PhD, Joins Children’s Hospital of Los Angeles as Director of Center for Personalized Medicine

Children’s Hospital Los Angeles (CHLA) has named Jaclyn Biegel, PhD, a leading academic expert on pediatric brain tumors, rhabdoid tumors, and cancer cytogenetics, as the Director of the Center for Personalized Medicine at CHLA. Dr. Biegel, who formerly served as Director of the Cancer Cytogenetics ...

Carmen Solórzano, MD, Named Chief of Surgical Oncology at Vanderbilt

Carmen Solórzano, MD, Professor of Surgery and Director of the Endocrine Surgery Center at Vanderbilt University Medical Center (VUMC), has been named Chief of the Division of Surgical Oncology and Endocrine Surgery in the Department of Surgery. Dr. Solórzano joined the Vanderbilt faculty in 2010...

Johannes W. Vieweg, MD, FACS, Named Founding Dean of Nova Southeastern University College of Allopathic Medicine

Nova Southeastern University (NSU), Fort Lauderdale, Florida, announced the appointment of Johannes W. Vieweg, MD, FACS, as Founding Dean of NSU’s College of Allopathic Medicine. The new college is aiming to welcome its first class of MD candidates in 2018, subject to achieving accreditation. Dr....

Global Cancer: The Current Reality and the Future Need for Action

The estimated number of cancer cases worldwide in 2008 was 12.7 million, with 7.6 million deaths. By 2030, it is estimated that there will be 22 million newly diagnosed cancer cases and 12 million deaths, shocking to contemplate in dollars and human suffering. Although this impending disaster has...

A Surgeon’s Inspiring Journey to Death

Every so often, a memoir comes along in which the story speaks to universal themes. For that magic to occur, the author must step aside at times and let others tell their story, too. Moreover, the writing must be clear, vibrant, and above all else honest to the core. The recently published memoir...

Emory and Winship Announce Sagar Lonial, MD, as Hematology and Medical Oncology Department Chair

Sagar Lonial, MD, an internationally renowned expert in the biology and treatment of patients with multiple myeloma, has been named Chair of the Department of Hematology and Medical Oncology within Emory University School of Medicine and Winship Cancer Institute. Dr. Lonial assumes this role...

Judy Keen, PhD, Announced as Director of Scientific Affairs at ASTRO

The American Society for Radiation Oncology (ASTRO) recently welcomed Judy Keen, PhD, as its Director of Scientific Affairs, a position created to expand research participation and collaboration in the field of radiation oncology. As the ASTRO lead on scientific affairs, Dr. Keen will develop and...

Suresh S. Ramalingam, MD, Named Deputy Director of Winship Cancer Institute

Suresh S. Ramalingam, MD, an internationally recognized lung cancer physician-investigator, has been named Deputy Director of Winship Cancer Institute of Emory University. He will also serve as Assistant Dean for Cancer Research in the Emory School of Medicine. In his role as Winship’s Deputy...

Four New U.S. Preventive Services Task Force Members Appointed

The U.S. Preventive Services Task Force has announced the addition of four new members: John W. Epling, Jr, MD, MSEd; Diane Medved Harper, MD, MPH, MS; C. Seth Landefeld, MD; and Carol M. Mangione, MD, MSPH. Like their fellow Task Force members, these experts in prevention and evidence-based...

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