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Advanced Practitioners Convene for Annual JADPRO Live at APSHO Meeting

The fourth annual JADPRO Live conference was held recently in conjunction with the Annual Meeting of the Advanced Practitioner Society for Hematology and Oncology (APSHO) on November 3–6, 2016, at the Gaylord National Hotel in National Harbor, Maryland. More than 1,100 individuals attended...

2016-2017 Oncology Meetings

NOVEMBER 21st Annual Perspectives in Thoracic OncologyNovember 18-19 • New York, New YorkFor more information:http://imedex.com/perspectives-thoracic-oncology-conference/index.asp Mayo Clinic Angiogenesis and Tumor Microenvironment Symposium: From Translational Research to Clinical Practice...

geriatric oncology

Meeting the Needs of Older Adults With Cancer

I have served as a patient advocate in many different ways since I was diagnosed with breast cancer in October 2000. For many years, my advocacy was focused on issues related to breast cancer. Since 2012, I have also been engaged in identifying and meeting the needs of the rapidly growing...

skin cancer

Study Looks for Optimal Dosing of Single-Agent Ipilimumab in Metastatic Melanoma

There has been debate as to the optimal dose of single-agent ipilimumab (Yervoy) in metastatic melanoma. A phase III study presented at the 2016 European Society for Medical Oncology (ESMO) Congress—the first to directly compare these doses—concluded that 10 mg/kg is more effective, but also more...

skin cancer

Small Study Tests Dual Checkpoint Blockade in High-Risk Stage III Melanoma

As neoadjuvant or adjuvant therapy for stage III melanoma patients with palpable disease, the combination of ipilimumab (Yervoy) plus nivolumab (Opdivo) was shown to be a promising, though also toxic, combination in a phase Ib study reported at the 2016 European Society for Medical Oncology (ESMO) ...

head and neck cancer

Better Quality of Life Reported in Patients With Head and Neck Cancer Receiving Nivolumab vs Chemotherapy

Standard treatment for advanced head and neck cancer—including chemotherapy and radiation—causes painful side effects that impair quality of life, as well as the ability to socialize and engage in daily life activities. A new study of patients with platinum-refractory recurrent, metastatic head...

health-care policy

How ASCO Is Preparing Members for MACRA

On October 14, 2016, the Centers for Medicare & Medicaid Services (CMS) announced its final policy on what physicians need to do to begin implementing the Quality Payment Program outlined in the Medicare Access and CHIP Reauthorization Act of 2015 ­(MACRA). The Quality Payment Program is a...

breast cancer

Study Raises Concerns About Timely Follow-up to Positive Mammogram for the Uninsured

A study by University of North Carolina (UNC) Lineberger Comprehensive Cancer Center researchers has found that younger, uninsured women in North Carolina had higher odds of missing a 60-day window for getting follow-up after an abnormal mammogram, even though research underscores the importance of ...

supportive care
survivorship

Sexual Pain Experienced by Women After Cancer Is Common and May Be Ignored

Painful sex in women after cancer treatment is relatively common, often treatable, and needs to be addressed by medical providers, a University of California (UC), Davis, oncologist and researcher suggests. Vanessa Kennedy, MD, a gynecologic oncologist at UC Davis Health System, said that with...

ASCO Applauds MACRA’s Focus on High-Quality, Patient-Centered Care

Editor’s note: As The ASCO Post went to press, the Department of Health & Human Services finalized a landmark new payment system for Medicare clinicians. The system, known as MACRA, (Medicare Access and CHIP Reauthorization Act of 2015), replaces the flawed Sustainable Growth Rate and will...

2016-2017 Oncology Meetings

OCTOBER 16th Biennial Meeting of the International Gynecologic Cancer SocietyOctober 29-31 • Lisbon, PortugalFor more information:http://igcs2016.com NOVEMBER 2016 Oncofertility Conference: Expanding Access to Emerging and Existing Oncofertility ServicesNovember 1-3 • Chicago, Illinois For more...

skin cancer

Association of PD-L1 Expression and Response to Pembrolizumab in Advanced Melanoma

In an analysis from the phase IB KEYNOTE-001 trial, Daud et al found that the level of programmed cell death ligand 1 (PD-L1) expression was associated with outcomes of pembrolizumab (Keytruda) treatment in patients with advanced melanoma. These findings were reported in the Journal of Clinical...

Free PQRS Reporting Now Available Through QOPI®; No Additional Reporting Required

ASCO is pleased to announce that oncology practices can now complete all of their Physician Quality Reporting System (PQRS)1 requirements through the Quality Oncology Practice Initiative (QOPI®) platform. All users will be able to use the QOPI system to fulfill the Oncology Measures Group set of 7...

prostate cancer

Study Finds PFS Benefit, but No Overall Survival Benefit, for Ipilimumab in Metastatic Castration-Resistant Prostate Cancer

Ipilimumab (Yervoy) was associated with prolonged progression-free survival—but not overall survival—compared with placebo in men with asymptomatic or minimally symptomatic chemotherapy-naive metastatic castration-resistant prostate cancer without visceral metastases, according to a...

lung cancer

Adding Pembrolizumab to Carboplatin/Pemetrexed Seems to Improve Response in Advanced Nonsquamous NSCLC

As reported by Langer et al in The Lancet Oncology, findings in a phase II cohort of the multicohort KEYNOTE-021 study showed that the addition of first-line pembrolizumab (Keytruda) to carboplatin/pemetrexed (Alimta) significantly increased the response rate in patients with advanced nonsquamous...

head and neck cancer

ESMO 2016: Nivolumab Maintains Function and Reduces Symptoms in Relapsed Metastatic Head and Neck Cancer

Nivolumab (Opdivo) maintains function and reduces symptoms in treatment of relapsed metastatic head and neck cancer, according to results from the CheckMate 141 trial presented by Harrington et al at the 2016 European Society for Medical Oncology (ESMO) Congress in Copenhagen, Denmark (Abstract...

health-care policy

HHS Finalizes MACRA Rule, ASCO Applauds Focus on High-Quality Patient-Centered Care

Today, the Department of Health & Human Services (HHS) finalized a landmark new payment system for Medicare clinicians that will continue the Administration’s progress in reforming how the health-care system pays for care. The Medicare Access and CHIP Reauthorization Act of ...

head and neck cancer

Improved Failure-Free Survival Reported With Addition of Induction Chemotherapy to Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma

In a Chinese phase III trial reported in The Lancet Oncology, Sun et al found that adding induction treatment with cisplatin, fluorouracil (5-FU), and docetaxel (TPF) to concurrent chemoradiotherapy improved failure-free survival in locoregionally advanced nasopharyngeal carcinoma. Study Details...

leukemia

Susan M. O’Brien, MD, Embraces the Challenge of Balancing Patient Care With Clinical Trial Investigation

Susan M. O’Brien, MD, one of the nation’s foremost leukemia experts, told The ASCO Post that she wanted to become a doctor since her earliest memories. “The idea of being able to help sick people always appealed to me,” said Dr. O’Brien, who was born in Manhattan but spent her formative years in...

cns cancers

Temozolomide vs Radiotherapy in High-Risk Low-Grade Glioma

In the phase III EORTC (European Organisation for Research and Treatment) 22033-26033 intergroup trial reported in The Lancet Oncology, Baumert et al found no progression-free survival difference between temozolomide chemotherapy and radiotherapy alone in patients with high-risk low-grade glioma....

breast cancer

Clinical Trials Actively Recruiting Patients With Early Breast Cancer

Pilot Study Title: Pilot Trial of an Implantable Microdevice for in Vivo Drug Sensitivity Testing in Patients With Early-Stage, HER2-Positive, or Triple-Negative Breast Cancer Receiving Neoadjuvant Therapy Study Type: Pilot/interventional/single-group assignment Study Sponsor and Collaborators:...

2016-2017 Oncology Meetings

OCTOBER American College of Surgeons Clinical CongressOctober 16-20 • Washington, DCFor more information:www.facs.org/clincon2016 ACCC 33rd National Oncology ConferenceOctober 19-21 • St. Louis, Missouri For more information: www.accc-cancer.org/meetings/slideshow-NOC2015/NOC2015.asp 48th Annual...

issues in oncology
health-care policy
survivorship

Why Curing Cancer Will Take Decades

This past summer, Eric S. Lander, PhD, President of the Broad Institute of the Massachusetts Institute of Technology and Harvard in Cambridge, Massachusetts, and Co-Chair of the President’s Council of Advisors on Science and Technology, raised a few eyebrows at the Aspen Ideas Festival when he...

hematologic malignancies

Update on Neoplastic Hematology: Review of Recent Clinical Trials

Here is a brief look at the study findings and clinical implications of several recent clinical trials on newer treatment options in neoplastic hematology. Attention is focused on several types of leukemia, Hodgkin lymphoma, and multiple myeloma. Leukemia Clinical Trial: INO-VATE ALL phase III...

issues in oncology
health-care policy

AACR’s Cancer Progress Report Hails Research Advances and Details Challenges Ahead

Although research advances in more effective therapies and diagnostics and improved screening technology over the past 2 decades have led to a 23% reduction in the cancer death rate in the United States, saving nearly 2 million lives,1 cancer remains the second leading cause of death after heart...

2016-2017 Oncology Meetings

OCTOBER International Cancer Imaging Society Meeting and 16th Annual Teaching CourseOctober 3-5 • Glasgow, ScotlandFor more information:http://www.icimagingsociety.org.uk/index.cfm?task=meetings 9th International Workshop on Waldenstrom’s Macroglobulinemia & Symposia on Multiple MyelomaOctober...

Cancer Survivorship Symposium Brings Together Oncologists and Primary Care Providers to Improve Patient Care

Significant advances in cancer care and treatment have led to a steady increase in survivorship—currently, more than 15.5 million cancer survivors are living in the United States. This number is only expected to grow, with an estimate of more than 20 million American cancer survivors in 2026.1 A...

ASCO Continues Active Involvement in Cancer Moonshot

This summer, ASCO continued its active involvement in Vice President Joe Biden’s Cancer Moonshot Initiative. ASCO joined the Vice President at the formal launch of the moonshot earlier this year, and since then, has discussed research and policy proposals to advance discovery in cancer treatment...

Expert Point of View: Allen Cheng, MD, DDS; Susan D. ­McCammon, MD

The study findings by Dr. ­Buchakjian and colleagues suggest it may be time to revisit the significance of frozen margin status, according to one of the session co-moderators, Allen Cheng, MD, DDS, of the Providence Cancer Center and Head & Neck Surgical Associates, both in Portland, Oregon....

palliative care
issues in oncology

Palliative Care 2016: Usage of Oregon’s Death With Dignity Act

In 1997, Oregon enacted a voter initiative allowing terminally ill residents to self-administer physician-prescribed medication to end their lives called the Oregon Death With Dignity Act (ORDWDA). Statute requires prescriptions written for lethal medications be reported; the state also collects...

palliative care
issues in oncology

Charles D. Blanke, MD, on Oregon’s Death With Dignity Act

Charles D. Blanke, MD, of the Oregon Health & Science University and Southwest Oncology Group, discusses the nearly 20 years’ experience with Oregon’s Death With Dignity (DWD) Act, a voter initiative that led to the first such law enacted in the United States (Abstract 44).

issues in oncology

Impact of Adherence to Cancer Prevention Guidelines on Diet, Physical Activity on Cancer Risk and Mortality

According to the American Cancer Society’s 2016 Cancer Facts & Figures, behaviors such as poor diet choices, physical inactivity, excess alcohol consumption, and unhealthy body weight account for about 20% of all cancers diagnosed in the United States and likely could be prevented with...

2016 - 2017 Oncology Meetings

SEPTEMBER 19th Annual Meeting of the Chinese Society of Clinical OncologySeptember 21-25 • Xiamen, ChinaFor more information:www.csco.ac.cn IASLC Chicago Multidisciplinary Symposium in Thoracic OncologySeptember 22-24 • Chicago, IllinoisFor more...

ASCO Announces 14 Practices Participating in the 2016 Quality Training Program

On July 14, ASCO announced the 14 practices participating in the 2016 Quality Training Program. The program is designed to train oncology health-care providers to investigate and implement data-driven quality improvement and manage clinical and administrative processes and outcomes. “One of the...

head and neck cancer

Use of Pembrolizumab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma After Platinum-Containing Therapy

On August 5, 2016, pembrolizumab (Keytruda) was granted accelerated approval for treatment of patients with recurrent or metastatic head and neck squamous cell carcinoma and disease progression on or after platinum-containing chemotherapy.1,2 As a condition of the accelerated approval, Merck is...

hematologic malignancies
leukemia
lymphoma
multiple myeloma

Roundup of Selected Abstracts in Multiple Myeloma, Acute and Chronic Leukemia, and Advanced Lymphoma

In June 2016, the European Hematology Association Congress convened in Copenhagen, Denmark. The educational and scientific program highlighted state-of-the-art clinical practice and the latest findings in hematology research. The ASCO Post brings its readers brief summaries of some of the important ...

Expert Point of View: Brian Burkey, MD, MEd

“This study pointed out what most head and neck/reconstructive surgeons know: Complex free flap reconstructions are associated with a relatively high readmission rate,” commented session co-moderator Brian Burkey, MD, MEd, Vice Chairman and Section Head of Head & Neck Surgery and Oncology, Head ...

head and neck cancer

Predictors of Readmission in Patients Requiring Free Tissue Reconstruction for Head and Neck Cancer

Certain factors increase the risk of unplanned readmission in the month after head and neck cancer resection requiring free tissue reconstruction, finds an analysis of data from the National Surgical Quality Improvement Program (NSQIP) of the American College of Surgeons.1 Nearly 1 in 10 patients...

palliative care

Palliative Care 2016: Early Palliative Care Improves Coping, Quality of Life for Patients With Incurable Cancers

A randomized clinical trial found that introducing palliative care shortly after a diagnosis of certain metastatic cancers greatly increases a patient’s coping abilities, as well as overall quality of life. Researchers also found that early integration of palliative care results in an...

lymphoma

Early Relapse in Follicular Lymphoma: Clinical Trial Data May Guide Management Decisions

Approximately 20% of patients with follicular lymphoma will relapse within 2 years of diagnosis. Although the optimal management of these patients has not been established, clinicians may be guided by data from recent clinical trials, according to Nathan H. Fowler, MD, Associate Professor and...

issues in oncology

Outpatient Bloodstream Infections Costly for Pediatric Stem Cell Transplant and Cancer Patients

Pediatric stem cell transplant and cancer patients often are discharged from the hospital with an external central venous line for medications that parents or other caregivers must clean and flush daily to avoid potentially life-threatening infections. If an outpatient develops a bloodstream...

health-care policy
issues in oncology

Researchers Question Process for Reviewing Coverage of 'Off-Label' Cancer Drug Use

A group of University of North Carolina (UNC) Lineberger Comprehensive Cancer Center researchers is calling for an overhaul of the process that determines which cancer drugs used off-label—or beyond their approved use—are reimbursed by federally funded health insurance in the United...

Helen F. Graham Cancer Center and The Wistar Institute Partner to Expand Research in Gene Editing

To accelerate breakthrough cancer research in the human genome, the Gene Editing Institute at Christiana Care’s Helen F. Graham Cancer Center & Research Institute has entered into an agreement with The Wistar Institute. The agreement expands the historic partnership between the Graham Cancer...

ASCO Announces 14 Practices Participating in the 2016 Quality Training Program

On July 14, ASCO announced the 14 practices that are participating in the 2016 Quality Training Program. The program is designed to train oncology health-care providers to investigate and implement data-driven quality improvement and manage clinical and administrative processes and outcomes. “One...

ASCO, Conquer Cancer Foundation Congratulate 2016 Grant and Award Recipients

The Conquer Cancer Foundation of ASCO (CCF) presented more than $6.1 million in grants and awards to nearly 250 promising oncology researchers at the 2016 ASCO Annual Meeting. The Conquer Cancer Foundation and ASCO congratulate the recipients on their contributions to the field of oncology and...

2016-2017 Oncology Meetings

AUGUST 16th World Congress on Cancers of the SkinAugust 31-September 3 • Vienna, AustriaFor more information: www.wccs2016.com 12th National Lymphedema Network International ConferenceAugust 31-September 4 • Dallas, TexasFor more information:https://cme.uchicago.edu/NLNIC16 SEPTEMBER ISOBM 2016...

breast cancer

A Complete Guide to Breast Surgery and Reconstruction

BookmarkTitle: Breast Cancer Surgery and Reconstruction: What’s Right for YouAuthor: Patricia Anstett, with photography by Kathleen GalliganPublisher: Rowman & LittlefieldPublication date: June 2, 2016Price: $35.00; hardcover, 224 pages Over the past 2 decades, we have seen tremendous...

issues in oncology
supportive care

ASCO’s 2016 Quality Training Program: Meet the First International Participant From Greece

Launched in 2014, ASCO’s Quality Training Program was developed to prepare oncology providers to design, implement, and lead successful quality-improvement activities in their practices. It is a 6-month program that includes a structured and facilitated improvement project selected by each...

survivorship

Late Cardiac Effects of Cancer Treatment

The combination of more precise diagnostic tools and advances in surgery, chemotherapy, radiation therapy, and targeted therapy in the treatment of cancer has led to unprecedented numbers of cancer survivors in the United States—more than 15.5 million, according to the latest figures from the...

issues in oncology

Have You Received Your Immune Checkpoint Inhibitor Yet?

“Have you received your immune checkpoint inhibitor yet?” I suspect St. Peter may have started asking this question routinely at the Pearly Gates to Heaven. If St. Peter has not, I am sure most oncologists have. With extensive media coverage on the approval of nivolumab (Opdivo) and pembrolizumab...

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