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Lisa Carey, MD, Named Division Chief of Hematology-Oncology, UNC School of Medicine, and Physician-in-Chief of the N.C. Cancer Hospital

Nationally recognized clinical researcher and physician Lisa A. Carey, MD, has been appointed Chief of the Division of Hematology and Oncology at the University of North Carolina School of Medicine and Physician-in-Chief of the N.C. Cancer Hospital. Dr. Carey, a member of the UNC faculty for more...

Memorial Sloan-Kettering Cancer Center Appoints José Baselga, MD, PhD, New Physician-in-Chief

Memorial Sloan-Kettering Cancer Center announced that José Baselga, MD, PhD, has been named Physician-in-Chief of Memorial Hospital. Currently, Dr. Baselga is Chief of the Division of Hematology/Oncology at Massachusetts General Hospital (MGH) and Associate Director of the MGH Cancer Center....

American Psychosocial Oncology Society Provides Helpline for Counseling Services

The American Psychosocial Oncology Society (APOS) offers a toll-free national Helpline as a resource to help people with cancer and their caregivers find counseling services in their own communities. Patients with cancer, caregivers, and advocacy organizations may obtain referrals for local...

issues in oncology

Tweeting at ASCO Annual Meetings Can Enhance the Experience

Tweeting at concerts or plays may earn you scornful looks or even stern warnings from ushers, but tweeting at the ASCO Annual Meeting may enhance the meeting experience for you and others. In a study comparing trends in Twitter use by physicians during the 2010 and 2011 ASCO Annual Meetings, some...

solid tumors
breast cancer
leukemia

New Studies Explore Exposure to Cancer-causing Agents

Key studies on cancer epidemiology and prevention delivered both reassuring and not-so-reassuring findings on exposure to agents believed to be cancer-promoting. Kala Visvanathan, MD, MHS, of The Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine and School of Public Health, Baltimore,...

breast cancer

States Aim to Increase Male Breast Cancer Awareness

Governor Chris Christie of New Jersey and Governor Deval Patrick of Massachusetts recently proclaiming October 21 through October 27 as Male Breast Cancer Awareness Week in their respective states. With this proclamation, New Jersey and Massachusetts become the third and fourth states to recognize...

issues in oncology

The Language of Cancer

For more than a year, Don S. Dizon, MD, FACP, has been blogging at ASCO Connection (connection.asco.org) about such diverse topics as cancer survivorship, the redesign of clinical studies based on patients’ molecular characteristics, and the power of laughter. Last May, Dr. Dizon tackled the impact ...

sarcoma

For Advanced Sarcomas, New Agents Prolong Remission but Not Survival

“We are beginning to understand the molecular biology underlying a portion of the 80 or so subtypes of sarcomas, and we hope this will lead to subtype-specific treatments,” said William D. Tap, MD, of Memorial Sloan-Kettering Cancer Center, New York, at the Best of ASCO Boston meeting. “And in...

prostate cancer
issues in oncology

FDA Approves Production of Imaging Agent to Detect Prostate Cancer

The FDA approved the production and use of Choline C 11 Injection, a positron-emission tomography (PET) imaging agent used to help detect recurrent prostate cancer. Choline C 11 Injection is administered intravenously to produce an image that helps to locate specific body sites for follow-up tissue ...

breast cancer
issues in oncology

FDA Approves First Ultrasound Imaging System for Dense Breast Tissue

The FDA approved somo-v Automated Breast Ultrasound System  (ABUS), the first ultrasound device for use in combination with a standard mammography in women with dense breast tissue who have a negative mammogram and no symptoms of breast cancer. The National Cancer Institute estimates that about 40% ...

FDA Approves New Treatment for Severe Neutropenia

The FDA recently approved Sicor Biotech’s tbo-filgrastim (Neutroval) to reduce the time certain patients receiving chemotherapy experience severe neutropenia. The new drug is a short-acting recombinant granulocyte colony-stimulating factor (G-CSF) agent. It is marketed as Tevagrastim in Europe,...

solid tumors

New Drug Application Submitted for Regorafenib to Treat GIST

Bayer HealthCare and Onyx Pharmaceuticals recently announced that Bayer HealthCare has submitted a New Drug Application (NDA) to the FDA for the oral multikinase inhibitor regorafenib for the treatment of metastatic and/or unresectable gastrointestinal stromal tumors (GIST) in patients whose...

breast cancer

Childhood Radiation Increases Breast Cancer Risk

The risk of developing breast cancer after receiving radiotherapy to the chest as a child are as high as those for BRCA1/2 mutation carriers, according to review of 1,268 cancer survivors and 4,570 female first-degree relatives of participants in the Women’s Environmental Cancer and Radiation...

SIDEBAR: Trials’ Shortcomings Leave Role of Induction Chemotherapy Unclear

Given certain shortcomings of the DeCIDE and PARADIGM trials, the true role of induction chemotherapy in head and neck cancer is still not clear, said George R. Blumenschein, Jr, MD, Associate Professor at The Unviersity of Texas MD Anderson Cancer Center, Houston, at the Best of ASCO San Diego...

Pivotal Trials in Head and Neck Cancers Yield Mixed Results

The latest research in head and neck cancer reported at this year’s ASCO Annual Meeting presents a mixed picture, according to George R. Blumenschein, Jr, MD, Associate Professor at The Unviersity of Texas MD Anderson Cancer Center, Houston, who presented the data at the Best of ASCO San Diego...

Conquer Cancer Foundation Honors Oncology Professionals for High-quality Research in Breast Cancer

More than 15 leading young oncology professionals were honored this year by the Conquer Cancer Foundation of the American Society of Clinical Oncology (ASCO) with 2012 Breast Cancer Symposium Merit Awards for their work in breast cancer research. These trainees submitted high-quality abstracts...

New ASCO Tobacco Cessation Practice Resources Will Offer Help for Providers as Well as Patients

It is well recognized that tobacco use increases the risk of several kinds of cancer. However, it is less well recognized that quitting tobacco remains important once an individual has been diagnosed with cancer, a common misconception held by oncologists and patients alike. Patients with cancer...

Stay Up to Date on New Patient Materials from Cancer.Net

Encourage your patients to use social media to stay up to date with the new resources available on Cancer.Net, such as the latest booklet on tobacco discussed on page 57. It is easier than ever for patients to get the latest cancer information on their computer or mobile device by subscribing to...

CancerLinQ Addressing Institute of Medicine Core Recommendations for ‘Learning Health System’

ASCO is applauding new Institute of Medicine (IOM) recommendations for establishing a “learning health system” in the United States, and is calling upon other medical specialties to join in achieving this vision of high-quality, high-value medical care. ASCO’s recently launched multiphased...

ASCO Achieves Highest Level of Accreditation for Continuing Medical Education Program

In July, ASCO was awarded “Accreditation with Commendation” (the highest level achievable) by the Accreditation Council for Continuing Medical Education (ACCME). Fewer than 25% of continuing medical education (CME) providers carry the “Commendation” status distinction, which signifies an...

cns cancers

Investigators’ Perseverance Pays Off in Treating Anaplastic Oligodendroglioma

The theme of this year’s key abstracts on central nervous system tumors is that “perseverance and analysis of long-term outcomes lead to practice-changing results and important insights,” according to Eric L. Chang, MD, of the USC Norris Cancer Hospital and Keck School of Medicine, Los Angeles, who ...

breast cancer

In DCIS, Radiotherapy Benefits ‘Good Risk’ Patients

Radiation therapy will improve outcomes for patients with ductal carcinoma in situ (DCIS), even if they are considered at low risk for recurrence, according to the Radiation Therapy Oncology Group (RTOG) 9804 trial.1 But the follow-up time is short, and the findings still leave some wiggle room,...

SIDEBAR: Treatment Decisions for Locally Advanced NSCLC Draw on 'Art of Medicine'

With treatment advances, there are now fewer absolutes in managing locally advanced NSCLC, according to Dr. Reckamp. “We are moving toward treating performance status 2 patients, and obviously, that is a heterogeneous group of people,” she elaborated. “For those who need a lot of care, you need to...

Progress, Slow but Sure, Seen for Current Lung Cancer Therapies

This year, we have some abstracts that help move things forward in lung cancer, maybe at a little bit slower pace than in previous years. But there are important points that we can learn from some of these abstracts,” commented Karen L. Reckamp, MD, of the City of Hope, who presented findings on...

Successful Use of Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy May Hinge on Prior Experience

A review of 60 consecutive patients with peritoneal carcinomatosis who underwent cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy (HIPEC)—sometimes called “hot chemotherapy”—found 0% mortality and 33% morbidity, with “a significant reduction of grade III/IV morbidity,...

Expert Point of View: Clifford A. Hudis, MD

Clifford A. Hudis, MD, of Memorial Sloan-Kettering Cancer Center, New York, said that the findings of the US Oncology study should be “very reassuring” to physicians and patients. “Several recent publications and SEER (Surveillance, Epidemiology, and End Results) database analyses have reported...

Novel Device May Eliminate Need for Re-excision after Lumpectomy

A novel device employed during breast surgery reduces the need for re-excision due to positive margins. This lessens patient anxiety, lowers treatment costs, and helps preserve the cosmetic appearance of the breast, according to a large prospective study reported at the 2012 Breast Cancer...

solid tumors

Noncolorectal GI Cancer Evidence Incorporated into Guidelines

The noncolorectal gastrointestinal cancer studies selected for this year’s Best of ASCO meetings include some whose results are being folded into practice guidelines or are good candidates for incorporation, according to Alexandria T. Phan, MD, Associate Professor at The University of Texas MD...

global cancer care

Viral Infection and Liver Cancer: A Global Health Crisis

It is estimated that at least 15% of all cancers worldwide can be attributed to infectious etiologies, mostly viral infections. At this year’s ASCO Annual Meeting, an intriguing session on virally induced cancers provided critical clues that could be of real practical value in advancing our battle...

NCCN Appoints Dr. Robert Carlson as Chief Executive Officer

The National Comprehensive Cancer Network (NCCN) has appointed Robert W. Carlson, MD, a leading expert in the field of breast medical oncology, as Chief Executive Officer. “Dr. Carlson is highly regarded in the oncology community, and NCCN is extremely pleased to appoint him as CEO. Over the last...

leukemia
lymphoma

Developments in Hematologic Cancers Include New Considerations in Treating Challenging Leukemias and Multiple Myelomas

Speakers at the National Comprehensive Cancer Network (NCCN) 7th Annual Congress on Hematologic Malignancies reviewed the current standard of care for various hematologic cancers and explored new concepts in treatment. Below are highlights from presentations on chronic myelogenous leukemia (CML),...

colorectal cancer

Regorafenib Approved for Advanced Colorectal Cancer

The FDA recently approved regorafenib (Stivarga) to treat patients with metastatic colorectal cancer that has progressed after treatment. Regorafenib is a multikinase inhibitor that blocks several enzymes that promote cancer growth. The drug was reviewed under the FDA’s priority review program that ...

issues in oncology

Despite Progress, Chemotherapy Drug Shortages Still Vex the Oncology Community

During the first week of November 2011, President Obama signed an Executive Order directing the FDA to take steps to help resolve the drug shortages that were affecting patient care across the country. The oncology community was hit especially hard; many of the drug shortfalls were generic...

Breast Cancer Symposium Features Surgical Data, Updated Results from BOLERO-2, and Other Important News

The annual Breast Cancer Symposium, held September 13 to 15 in San Francisco, is jointly sponsored by ASCO, the American Society for Radiation Oncology, the American Society of Breast Disease, the American Society of Breast Surgeons, the National Consortium of Breast Cancers, and the Society of...

pancreatic cancer

Daniel Von Hoff, MD, Recognized with Award as Research Leader in Pancreatic Cancer

Daniel Von Hoff, MD, Physician-In-Chief of the Translational Genomics Research Institute (TGen) is the first recipient of the Lori Groetken Memorial Lecture and Award presented recently at Washington University in St. Louis. He delivered his lecture “A Relentless Molecular Pursuit Approach to Take...

supportive care
pain management

SIDEBAR: Don’t Expect Direct Questions from Patients about Pain

Just asking patients “Is there something else you want to address in the visit,” rather than “Is there anything else you want to address in the visit today,” dramatically reduced patients’ unmet concerns during a primary care visit, according to a 2007 study.1 That learning can be applied to...

supportive care
pain management

Pain Remains Prevalent among Oncology Outpatients, with Odds of Undertreatment Twice as High among Minority Patients

In 1994, a landmark study of pain among oncology outpatients prompted a host of pain management initiatives.1 More than 18 years later, a recent study among more than 2,000 cancer outpatients has found that “one-third of the patients who had pain or used analgesics received inadequate treatment for ...

Cancer Genome Atlas Network Reports Comprehensive Molecular Portraits of Breast Tumors

The Cancer Genome Atlas Network recently reported findings of analyses of primary breast cancers in a total of 825 patients using genomic DNA copy number arrays, DNA methylation, exome sequencing, mRNA arrays, microRNA sequencing, and reverse-phase protein arrays.1 Integration of information across ...

Despite the Rhetoric, Cancer Care Costs Keep Skyrocketing: Is There a Solution?

Although health-care experts routinely agree that the rising costs of oncology services are untenable, there is disagreement about how to reduce expenditures without harming access and quality of care. At this year’s ASCO Annual Meeting, Thomas J. Smith, MD, FACP, offered some interesting ideas...

gynecologic cancers

SIDEBAR: All Eyes on Trials of IV vs IP Chemotherapy for Ovarian Cancer

The positive findings from the NOVEL trial add to the debate about how intravenous (IV) chemotherapy stacks up against intraperitoneal (IP) chemotherapy when treating ovarian cancer and the role of dose-dense approaches in general, according to Jonathan S. Berek, MD, of the Stanford Women’s Cancer...

gynecologic cancers

SIDEBAR: Future of PARP Inhibitors in Ovarian Cancer Hangs in Balance

"It’s become clear that the PARP inhibitors in general … are active in this disease, and we are just trying to find out the level of activity and … get to the point hopefully where at least one of these agents will be approved for use” in ovarian and related cancers, commented Jonathan S. Berek,...

gynecologic cancers

Major Strides Seen in Treatment of Gynecologic Cancers

Research reported at this year’s ASCO Annual Meeting shows major strides in treating ovarian and cervical cancers, suggesting the potential of new agents and adding evidence in areas where optimal management is unclear, according to Jonathan S. Berek, MD, of the Stanford Women’s Cancer Center,...

multiple myeloma

Novel Drug Combinations Present New Hope for Effective Treatments in Multiple Myeloma

Developing early-phase clinical trials that incorporate combinations of novel agents targeting different pathways in the hematologic cancer multiple myeloma is a leading focus of the work of Sagar Lonial, MD, Professor of Hematology and Vice Chair of Clinical Affairs in the Department of Hematology ...

Now in Spanish: Cancer in Older Adults

Tell your patients about Cancer in Older Adults, Cancer.Net’s newest Spanish language booklet for older adults and their family and friends. The content of the booklet is adapted from the ASCO University Module, Cancer Care for Older Patients. It provides information on the physical and emotional...

CancerProgress.Net Adds New Resources to Highlight Progress in Clinical Cancer Research

ASCO’s CancerProgress.Net (www.CancerProgress.Net), a dynamic website demonstrating four decades of progress against cancer, has added new resources that will enable site users to learn more about progress in cancer treatment, prevention, screening, and diagnosis. Interactive Cancer Timelines...

Fellowship Breathes ‘LIFe’ into the Careers of Young Oncologists in Developing Countries

The Conquer Cancer Foundation of the American Society of Clinical Oncology supports one-on-one training and research grants for the brightest minds in cancer care around the world through the Long-term International Fellowship (LIFe) and other programs. Through this 1-year fellowship, early-career...

Karnofsky Award Winner Honors Mentors through Gift to Conquer Cancer Foundation

Kanti R. Rai, MD, and his wife Susan have been loyal donors to the Conquer Cancer Foundation for the past 9 years, but in 2012, a momentous occasion in his career inspired Dr. Rai to make a unique gift. A Moment of Reflection In the spring of 2012, Dr. Rai, an internationally recognized expert on ...

health-care policy

American Association for Cancer Research Mourns the Loss of Senator Arlen Specter

The American Association for Cancer Research (AACR) mourns the loss of Arlen Specter, who represented Pennsylvania in the U.S. Senate from 1981 to 2011. With his passing, the cancer research and biomedical science community lost one of its greatest supporters and promoters. During his five terms...

health-care policy

Expert Point of View: Frank McCormick, PhD

The ASCO Post asked AACR President Frank McCormick, PhD, Director, UCSF Helen Diller Family Comprehensive Cancer Center, about the ongoing problem of health-care disparities among minorities and other subpopulations. First, can the Patient Protection and Affordable Care Act lessen these...

kidney cancer

Expert Point of View: Tim Eisen, MD, and Robert Figlin, MD

Over the past few years, we have gone from famine to feast.… We now have sorafenib [Nexavar] and sunitinib [Sutent], temsirolimus [Torisel], and everolimus [Afinitor], and interferon plus bevacizumab [Avastin] for treatment of metastatic renal cell carcinoma. If these drugs [in COMPARZ] are...

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