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issues in oncology

Preparing for the Next Superstorm: Protecting Patients during Natural Disasters 

When Hurricane Sandy slammed into the East Coast last October, the magnitude of devastation it left in its wake exceeded even the most dire predictions. Eighty mile per hour winds and record storm surges destroyed antiquated electrical grids and flooded subway stations, leaving much of New York...

lung cancer
palliative care

Patients Receiving Palliative Radiation Therapy for Metastatic Non–Small Cell Lung Cancer May Be Overtreated 

Many patients receiving palliative radiation therapy to the bone or chest for metastatic non–small cell lung cancer (NSCLC) may be receiving a greater number of treatments and higher doses than are supported by current evidence, according to a Cancer Care and Outcomes Research and Surveillance...

breast cancer
integrative oncology

Qigong Practice Associated with Quality-of-life Benefits in Women Undergoing Radiation Therapy for Breast Cancer 

Qigong (“qi” or “chi” = energy flow, “gong” = skill or achievement) is an integrated mind-body exercise and meditative practice that involves rhythmic breathing coordinated with repetition of fluid movements and calm focus on the body. A study reported in Cancer by Zhen Chen, MD, and colleagues...

issues in oncology

NCI Guide Helps Providers Get Adolescent and Young Adult Patients Involved in End-of-life Care 

Enabling adolescent and young adult (AYA) patients to become involved in advance care planning can help parents and health-care agents make informed decisions, alleviate distress, and possibly improve the patients’ quality of life, according to researchers at the National Cancer Institute’s...

SIDEBAR: Patient Advocate Scholarship Program 

The Conquer Cancer Foundation’s Patient Advocate Scholarship Program enables advocates to attend ASCO meetings so they may further educate themselves on important advances in their areas of interest. The scholarship program is one of many programs ASCO and the Conquer Cancer Foundation provide for...

ASCO Leadership Development Program Participants 'Give Back' by Supporting the Conquer Cancer Foundation

In the fast-paced world of oncology, where the science of patient care is constantly evolving, it is critical for practitioners—and, by extension, their Society—to consistently be one step ahead. For ASCO and the Conquer Cancer Foundation, that means maintaining a strong focus not only on the...

SIDEBAR: Samuel M. Silver, MD, PhD, Elected Chairman of NCCN Board of Directors 

Samuel M. Silver, MD, PhD, of the University of Michigan Comprehensive Cancer Center, has been elected Chairman of the National Comprehensive Cancer Network (NCCN) Board of Directors. Dr. Silver was previously Vice Chairman of the Board and succeeds Thomas A. D’Amico, MD, of the Duke Cancer...

survivorship

Sexual Health after Cancer: Communicating with Your Patients 

Studies show virtually all cancer survivors will experience some form of sexual dysfunction following a cancer diagnosis and treatment. Yet few cancer survivors seek help for physical problems they may be experiencing, such as vaginal dryness, dyspareunia, chemically induced menopause, reduced...

Saul N. Weingart, MD, PhD, Named New Chief Medical Officer of Tufts Medical Center

Tufts Medical Center has appointed Saul N. Weingart, MD, PhD, of Newton, Massachusetts as its next Chief Medical Officer.  Dr. Weingart is currently serving as Vice President for Quality Improvement and Patient Safety at Dana-Farber Cancer Institute in Boston. He is a nationally renowned leader in...

NCCN Patient Guidelines for Adolescents and Young Adults 

The National Comprehensive Cancer Network (NCCN) has issued new NCCN Guidelines for Patients, titled “Caring for Adolescents and Young Adults [AYA].” These guidelines fill an unmet need in oncology, as Peter F. Coccia, MD, Chair of the NCCN Guidelines Panel for Young Adult Oncology and a member of...

issues in oncology
supportive care
symptom management

Automated Telephone Monitoring Reduces Chemotherapy-related Symptoms 

The use of an automated computer-based telephone monitoring system to assess symptoms during outpatient chemotherapy—and provide intervention where appropriate by a nurse practitioner—substantially reduced the number of days with symptoms in a study reported at the 18th Annual Conference of the...

lung cancer

Lessons of 2 Decades' Experience with CHESS

Our work on an Internet-based intervention for lung cancer confirmed what many other studies have shown about technologic interventions for health-care consumers—that such interventions can improve quality of life for caregivers and patients.1 We expected this result in part because of the...

breast cancer
issues in oncology
survivorship

Breakthroughs in Targeted Therapies for Breast Cancer Are Improving Patient Survival Rates 

For more than 20 years, José Baselga, MD, PhD, has devoted his medical and scientific career to caring for breast cancer patients and the development of novel molecular targeted agents to treat the disease. From 1996 to 2010, he was Head of the Oncology Department of Vall d’Hebron University...

breast cancer

Reducing Incidental Cardiac Irradiation during Breast Radiotherapy  

In the treatment of breast cancer, a wealth of data from prospective clinical trials and meta-analyses has documented the benefits of radiation to prevent local-regional recurrence and improve survival. Accordingly, important quality indicators in breast cancer care include: (1) receipt of...

health-care policy
legislation

Sequestration's Impact on Cancer Care  

On March 1, the deficit-budget mechanism known as sequestration took effect, triggering $85 billion in across-the-board cuts to most federal agencies over the remaining 7 months in fiscal year 2013. The total federal deficit reduction budget under the Budget Control Act of 2011 calls for $1.2...

issues in oncology

Francis Crick's Discovery of the Structure of DNA Transformed 20th Century Biologic Sciences 

“My Dear Michael, Jim Watson and I have probably made a most important discovery. We have built a model for the structure of des-oxy-ribose-nucleic-acid, called DNA for short.… In other words we think we have found the basic copying mechanism by which life comes from life,” wrote Francis Crick,...

Utilizing the Power of Rapid Learning Health-care Systems to Improve Patient Care 

Lynn Etheredge’s career in shaping national health-care and social policy spans more than 4 decades and four Presidential administrations. He was the lead analyst in the development of health insurance proposals for Medicare and Medicaid while working in the White House Office of Management and...

Expert Point of View: Giulia Veronesi, MD

The study discussant, Giulia Veronesi, MD, of the Division of Thoracic Surgery, European Institute of Oncology, Milan, Italy, said that diagnostic algorithms aim to strike a balance between a too-invasive workup that exposes screened persons to useless invasive procedures and overtreatment, and...

geriatric oncology
issues in oncology

Improving the Care and Study of Older Patients with Cancer 

Predicting toxicity in older patients receiving chemotherapy is an important clinical problem. It has been shown that standard oncology measures such as performance status are not adequate to predict outcomes in the elderly. Clinical measures that are important in geriatric oncology are not...

palliative care

Death with Dignity Program at Seattle Cancer Care Alliance 

After passage of the Washington Death with Dignity Act in November 2008, the Seattle Cancer Care Alliance—the site of outpatient care for patients with cancer from Fred Hutchinson–University of Washington Cancer Consortium—developed a Death with Dignity program. The program is adapted from existing ...

palliative care

One Cancer Center's Approach to Death with Dignity

In November 2008, the Washington State legislature passed the Washington Death with Dignity Act allowing patients with a terminal diagnosis and less than 6 months to live to request and self-administer lethal medication. After considerable internal debate, our cancer center elected to develop a...

For Renowned Researcher, Seeing Basic Science Turn into Promising Therapies Is the 'Holy Grail' of Oncology

“From bench to bedside” is a phrase that captures the essence of modern oncology: Researchers at the bench seek to solve the biologic puzzles of cancer that can translate into the development of therapeutics delivered at the bedside. Owen N. Witte, MD, has spent most of his career as a basic bench...

Innovative Leader in Oncology Is Committed to Tackling the Most Critical Issues in Managed Care

“I’m a Nebraskan,” said Lee N. Newcomer, MD, MHA, a leader in the oncology community who is well known for his innovative efforts to align physician payment and quality of care in ways that will best configure to the rapidly changing health-care environment. Speaking in the flat vowels and neutral...

Pioneering Oncologist's Research on Cisplatin Revolutionized Testicular Cancer Treatment

Lawrence H. Einhorn, MD, grew up in Dayton, Ohio, in a time and place that he describes as pleasant and community-oriented. Throughout his distinguished career, Dr. Einhorn has maintained strong roots in the Midwest. “After finishing high school, I did my undergrad at Indiana University and went to ...

In Memoriam: ASCO Remembers Founding Member Jane Cooke Wright, MD

Earlier this year, ASCO and the oncology community at large lost a true pioneer, mentor, and renowned researcher. It is with great sadness that we mark the passing of Jane Cooke Wright, MD, one of seven founding members of ASCO—the only woman among the founders—and the Society’s first...

prostate cancer

Radium-223 Dichloride for Castration-resistant Prostate Cancer with Symptomatic Bone Metastases 

In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms, administration recommendations, safety profiles, and other essential information needed for the appropriate clinical use of these drugs. Indication On May 15, 2013, radium Ra 223 dichloride (Xofigo) was...

issues in oncology

Co-discoverer of DNA Double Helix, James Watson, PhD, Offers a New Theory on Cancer Progression 

Despite his fame as co-discoverer—along with Francis Crick, PhD—of the double-helix structure of deoxyribonucleic acid (DNA) in 1953, that accomplishment is not what James Dewey Watson, PhD, came to talk about during a recent presentation he gave at the World Science Festival in New York. Instead,...

colorectal cancer

Addition of Brivanib to Cetuximab in Chemotherapy-refractory Metastatic Wild-type KRAS Colorectal Cancer: Key Results 

The addition of a combination of epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) inhibitors to chemotherapy has not improved outcome in first-line treatment of advanced colorectal cancer. However, in early-phase evaluation, the addition of the investigational...

health-care policy

ASCO Urges Administration to Provide Clear Affordable Care Act Guidance on Protecting Patient Access to Clinical Trials

ASCO has joined more than 50 other organizations in urging the Administration to issue regulations or guidance before January 2014 to ensure health plans implement an important provision of the Affordable Care Act that would remove a critical obstacle to patients interested in participating in...

issues in oncology

ASCO Targets Health Disparities, Need for Research in Achieving Health Equity

The American Society of Clinical Oncology (ASCO), the Association of Black Cardiologists (ABC), and the Heart Failure Society of America (HSFA) recently held a Capitol Hill Briefing to draw attention to health disparities among minority and underserved patients and opportunities to achieve health...

Expert Point of View: Charles Vogel, MD, Larry Norton, MD, and Andrew D. Seidman, MD

A number of breast cancer specialists commented on the value of the Southwest Oncology Group (SWOG) 0221 data. Charles Vogel, MD, Professor of Medicine at the University of Miami Health System, commented after the presentation, “This is a potentially important abstract because of the wide variety...

breast cancer

Head-to-Head Matchup Shows Adjuvant Taxane Schedules Equally Effective  

In the treatment of early breast cancer, outcomes are equivalent whether paclitaxel is delivered weekly or every 2 weeks, though the weekly schedule may be better tolerated, according to the results of a phase III trial presented at the 2013 ASCO Annual Meeting.1 “The progression-free survival...

hematologic malignancies

Leukemia & Lymphoma Society Appoints New Administrative Officer

The Leukemia & Lymphoma Society recently announced the appointment of Rosemarie Loffredo as its new Chief Administrative Officer and Chief Financial Officer. In this newly created role, Ms. ­Loffredo will help ensure the Society achieves the goals of its long-range strategic plan. She will lead ...

SIDEBAR: Key Issues in Joint Commission Statement by American Psychosocial Oncology Society,  Association of Oncology Social Work, and Oncology Nursing Society 

It is imperative that [Commission on Cancer]-accredited programs adopt a universal definition of distress. We concur with the National Comprehensive Cancer Network definition of distress as an “unpleasant emotional experience of a psychological (cognitive, behavioral, emotional), social, and/or...

issues in oncology

A Look Ahead: The Next Decade in Pediatric Oncology 

The past 10 years have seen dramatic advances in cancer care, especially in better screening methods and earlier detection, genomic sequencing, and more effective therapies, which have led to increased survival rates in both childhood and adult cancers. According to the National Cancer Institute...

Michael J. Stamos, MD, Elected ASCRS President, Terry C. Hicks, MD, Chosen President-Elect

Michael J. Stamos, MD, Orange, California, was elected President of the American Society of Colon and Rectal Surgeons (ASCRS) at the Society’s Annual Meeting in Phoenix, succeeding Alan G. Thorson, MD, Omaha. Dr. Stamos is the John E. Connolly Professor and Chair of the Department of Surgery at the ...

SIDEBAR: Program Background

Partners for Cancer Care and Prevention holds that early detection and high-quality treatment of breast and cervical cancer save lives. The organization exists to build community capacity for the creation of high-quality, holistic breast and cervical health programs managed by the local health...

global cancer care

Program Aims to Overcome Barriers to Early Cancer Care in Colombia 

According to a report from the International Agency for Research on Cancer’s  GLOBOCAN project, one woman dies every minute from breast cancer and one woman dies every 2 minutes from cervical cancer.1 The majority of these deaths occur in developing countries, where access to health care is limited ...

lung cancer

Low-dose CT Screening for Lung Cancer: Details of First Round of Screening in National Lung Screening Trial 

The National Lung Screening Trial found that 3 years of annual screening with low-dose helical computed tomography (CT) reduced lung cancer mortality compared with chest radiography in older persons who were heavy smokers.1 The Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial also...

issues in oncology

ASCO Examines the Future of Cancer Care Over the Next 2 Decades 

While the many scientific advances over the past 50 years have led to improved outcomes for millions of patients with cancer—increasing the number of survivors from just 3 million in the 1970s to nearly 14 million today—the next 20 years promise to bring even greater opportunities to improve the...

head and neck cancer

Many Patients With Head and Neck Cancer Report Being Depressed, but Few Use Mental Health Services  

Despite a relatively high rate of depression among patients with head and neck cancer following radiation therapy, mental health services were severely underutilized in this group, concluded researchers who analyzed questionnaire results from 211 patients. The patients had been previously treated...

issues in oncology

The Oncologist as Author: On Guiding Patients Through Cancer 

When Tumor Is the Rumor and Cancer Is the Answer is the guidebook to cancer that Kevin P. Ryan, MD, FACP, COL, USAF (ret) wished his patients had during his 30 years of practicing oncology. The book, recently published by AuthorHouse, is an authoritative, inspiring, and even philosophical guide for ...

PCORI Board Approves $114 Million for Patient-Centered Outcomes Research

The Patient-Centered Outcomes Research Institute (PCORI) Board of Governors recently approved 71 awards, totaling more than $114 million over 3 years, to fund comparative clinical effectiveness research designed to answer questions most important to patients and those who care for them. The awards...

Donatori di Musica Initiative Creates a Unique Environment for Oncology Patients 

“Surely again, to heal men’s wounds by music’s spell.” —Euripides, Medea (480-406 BC) Commonly defined as organized sound, music has a unique power to stir human emotions, moods, and impressions. The salutary effect of music on the sick has been reported since antiquity. Aristotle and Plato wrote...

solid tumors

Felice Schnoll-Sussman, MD, Named Director of Jay Monahan Center for Gastrointestinal Health at NewYork-Presbyterian/Weill Cornell 

NewYork-Presbyterian/Weill Cornell Medical Center has appointed Felice Schnoll-Sussman, MD, Director of its Jay Monahan Center for Gastrointestinal Health. Dr. Schnoll-Sussman, has served as the Center’s Director of Research since 2007 and Acting Director since 2012. As Director, Dr....

global cancer care

View From a Cancer Ward in Botswana 

Julie Livingston, PhD, MPH, is a Professor of History at Rutgers University. She is also an African historian with interdisciplinary training in public health and anthropology. Among other issues, her work considers the challenges of delivering oncology services in southern Africa, where there is a ...

global cancer care

Aftermath of the AIDS Pandemic: Cancer Care in Botswana  

The Republic of Botswana is slightly smaller than the state of Texas and with a population of just over 2 million people it is one of the world’s most sparsely populated countries. Botswana was among Africa’s poorest countries at the time it gained independence from the United Kingdom in 1966....

health-care policy

Trying to Improve Value in Cancer Care: An Experiment

One of the more significant problems in modern oncology practice is to provide increased value at a time when costs are spiraling upward, and new parameters of “success” are being introduced into the equation—most visibly, inside the Beltway in Washington, DC. Thus, oncologists will need to address ...

Association of Community Cancer Centers' 2013 Innovator Award Recipients Announced

Ten cancer programs that have developed pioneering solutions to address the challenges of treating cancer patients have received the Association of Community Cancer Centers’ (ACCC) 2013 Innovator Awards. Established in 2011, ACCC’s Innovator Awards are sponsored by GE Healthcare. The award...

issues in oncology
legislation

A Look Ahead: How the FDA Is Adapting in the Era of Precision Medicine  

Dubbed “Cancer Czar” by the media, Richard Pazdur, MD, Director of the U.S. Food and Drug Administration (FDA) Office of Hematology and Oncology Products, said he has the “best job in oncology, with a unique vantage point in cancer drug development.” An oncologist for more than 30 years—including...

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