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Showing 30901 - 30950FDA Approves Rolapitant for Prevention of Chemotherapy-Induced Nausea and Vomiting
The U.S. Food and Drug Administration (FDA) approved rolapitant (Varubi) to prevent delayed-phase chemotherapy-induced nausea and vomiting. Rolapitant is approved in adults in combination with other antiemetic agents that prevent nausea and vomiting associated with initial and repeat courses of...
ASTRO Awards Seven Physician-Researchers $675,000 in Grants for Radiation Oncology Research
The American Society for Radiation Oncology (ASTRO) has selected seven leading physician-researchers to receive a total of $675,000 in awards and grants to advance radiation oncology research. Together, the grants will support studies in cancer biology, radiation physics, translational research,...
Carl H. June, MD, Awarded the 2015 Watanabe Prize
Carl H. June, MD, an internationally recognized leader in the growing field of immunotherapy, was awarded the Watanabe Prize at the 7th Annual Meeting of the Indiana Clinical and Translational Sciences Institute (CTSI) on September 11 on the campus of Indiana University–Purdue University...
Texas Center for Proton Therapy Names Chang Chang, PhD, Director of Physics
Chang Chang, PhD, a leader in proton therapy medical physics, has been named Director of Physics at Texas Center for Proton Therapy. Previously, as Senior Medical Physicist at ProCure Proton Therapy Center in Somerset, New Jersey, Dr. Chang was involved in the commissioning of new proton technology ...
2015 ASTRO Gold Medal Recipients Announced
The American Society for Radiation Oncology (ASTRO) has chosen three radiation oncology physicians and researchers to receive the 2015 ASTRO Gold Medal: Carl R. Bogardus, Jr, MD, FASTRO; Carl M. Mansfield, MD, ScD (Hon), FASTRO; and James B. Mitchell, PhD, FASTRO. Drs. Bogardus, Mansfield, and...
Tari King, MD, Named Chief of Breast Surgical Services at Dana-Farber/Brigham and Women’s Cancer Center
Tari King, MD, has been appointed Chief of Breast Surgery at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC). Dr. King will hold appointments at Brigham and Women’s Hospital, Faulkner Hospital, and Dana-Farber Cancer Institute. Dr. King will oversee breast surgery in the DF/BWCC, which...
One Doctor’s Road to Palliative Care Services in the Inner City
St. Barnabas Hospital is located in the heart of Bronx, New York, and as such, it has a culturally diverse, largely poor, patient population. The backbone of successful palliative care services is the doctor-patient communication bonding process. However, many of the patients with late-stage cancer ...
James P. Allison, PhD, Wins Clinical Medical Research Lasker-DeBakey Award
James P. Allison, PhD, Chair of Immunology at The University of Texas MD Anderson Cancer Center, has been named the 2015 winner of the Lasker-DeBakey Clinical Medical Research Award from the Albert and Mary Lasker Foundation. The Lasker awards, in their 70th year, honor major achievements in basic...
Expert Point of View: James Jett, MD, and Martin J. Edelman, MD
James Jett, MD, of National Jewish Health in Denver, moderated the press briefing where the study results were presented and called MAPS a “landmark study” that could change the standard of care in this malignancy. Martin J. Edelman, MD, Professor of Medicine at the University of Maryland,...
Bevacizumab Plus Standard Chemotherapy Improves Survival in Mesothelioma
The standard of care for malignant pleural mesothelioma may be poised for change, judging by results from a study by the French Cooperative Thoracic Intergroup. The addition of bevacizumab (Avastin) in the first-line setting to the current standard of care, pemetrexed (Alimta)/cisplatin, improved...
For Big Data Projects, Bigger Is Better
In an interview with The ASCO Post, Robert S. Miller, MD, FACP, Senior Director, Quality and Guidelines, ASCO, and Medical Director, CancerLinQ™, described how the system could work with data specific to radiation oncology. “The system is in the rapid build phase now, what we are calling the...
Radiation Oncology Looks to Collaboration for Big Data Systems
Radiation oncologists dream of a day when, faced with a new patient sitting in their office, they can quickly consult a computer database offering specific treatment recommendations based on accurate, freshly updated data from millions of previously treated patients with cancer. To hasten that day, ...
Managing High-Risk Patients With Febrile Neutropenia
Febrile neutropenia is of particular concern in high-risk patients who have undergone stem cell transplant, according to William J. Hogan, MB, BCh, Assistant Professor of Medicine at the Mayo Clinic in Rochester, Minnesota. Dr. Hogan delivered an update on febrile neutropenia management in this...
Rolapitant for Prevention of Delayed Chemotherapy-Induced Nausea and Vomiting
In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms, administration recommendations, safety profiles, and other essential information needed for the appropriate clinical use of these drugs. On September 2, 2015, rolapitant (Varubi) was approved for use in...
HPV-Positive Head and Neck Cancer: When Can Chemotherapy Be Omitted?
Are there patients with locally advanced squamous cell carcinoma of the head and neck associated with human papillomavirus (HPV) for whom chemotherapy can be omitted? Experts debated this question at the 2015 Debates and Didactics in Hematology and Oncology Conference in Sea Island, Georgia,...
Yale Cancer Center Receives $11 Million SPORE Grant for Lung Cancer Research
The National Cancer Institute (NCI) recently awarded Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven a Specialized Program of Research Excellence, or SPORE, grant worth $11 million. The Yale SPORE will launch a new research program in non–small cell lung cancer. The new research...
NCI Awards SPORE Grant to Mayo Clinic Multiple Myeloma Research Team
A team of Mayo Clinic Cancer Center scientists has been awarded a Specialized Program of Research Excellence (SPORE) grant in multiple myeloma from the National Cancer Institute. The Center is one of only three cancer centers to receive a SPORE grant for multiple myeloma cancer research. “With...
Jinghui Zhang, PhD, Named Chair of Computational Biology at St. Jude
St. Jude Children’s Research Hospital has named Jinghui Zhang, PhD, as the first Chair of the Department of Computational Biology. She will hold the St. Jude Endowed Chair in Bioinformatics. Computational biology applies mathematics and computer science to the study of genomics, systems biology,...
Fred R. Hirsch, MD, PhD, Presented With 2015 Addario Lectureship Award
The Bonnie J. Addario Lung Cancer Foundation (ALCF) honored Fred R. Hirsch, MD, PhD, with the 2015 Addario Lectureship Award for his continued leadership and expertise in lung cancer treatment and research. Dr. Hirsch, CEO of the International Association for the Study of Lung Cancer (IASLC),...
ASH Honors John C. Byrd, MD, With 2015 William Dameshek Prize
The American Society of Hematology (ASH) will present the 2015 William Dameshek Prize to John C. Byrd, MD, of The Ohio State University Comprehensive Cancer Center–Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) for his contributions to the development of...
Mantle Cell Lymphoma: Is Transplantation Still Necessary?
Autologous stem cell transplantation has played a critical role in the treatment of mantle cell lymphoma, but in the age of novel treatments, is it always warranted? Two experts in the field explored the question at the 2015 Debates and Didactics in Hematology and Oncology Conference sponsored by...
About the Summit
The research summit was part of the ASCO Obesity Initiative, which sought to increase awareness of the links between obesity and cancer and to foster research in this area that evaluated the impact of weight loss and increased activity on cancer outcomes. There have been hundreds of observational...
ASCO Statement Addresses Recommendations for Obesity Clinical Trials in Cancer Survivors
As reported in the Journal of Clinical Oncology by Jennifer A. Ligibel, MD, of Dana-Farber Cancer Institute, and colleagues, ASCO has issued a statement providing recommendations for obesity clinical trials in cancer survivors.1 ASCO convened the Research Summit on Advancing Obesity Clinical...
Dr. Cohen’s Approach to Managing Double-hit Lymphoma
All patients with aggressive non Hodgkin lymphoma should be evaluated for MYC and BCL2/6 gene expression, if possible, by fluorescent in situ hybridization and immunohistochemistry. Several intensive treatment regimens are available. Dr. Cohen favors dose-adjusted R-EPOCH for patients with...
Double-Hit Lymphoma: Many Treatment Strategies, No Standard of Care
"Double-hit lymphoma” represents a challenging malignancy without a standard-of-care treatment, although outcomes for some patients are better than was once believed, according to Jonathon B. Cohen, MD, Assistant Professor of Hematology and Medical Oncology at Emory University, Atlanta. Dr. Cohen...
Making Their Voices Heard: 118 Oncologists Speak Out About Stemming the High Cost of Cancer Drugs
In a bold move to shed light on the ramifications of the ever-increasing cost of cancer drugs for patients with cancer and for the health-care system, 118 prominent oncologists came together to write a commentary in Mayo Clinic Proceedings detailing their concerns.1 To learn more about these...
Our Children’s Future Is Our Responsibility
Cancer prevention is a child-care issue. With many of cancer’s instigators planting their seeds during childhood, we—as a profession and as a nation—must seize this important window of opportunity to protect the health and well-being of future generations. Current estimates suggest that up to...
Expert Point of View: Glenwood Goss, MD, FRCPC, FCPSA
Glenwood Goss, MD, FRCPC, FCPSA, Professor of Medicine and Director of Clinical and Translational Research at the Ottawa Hospital Cancer Centre and University of Ottawa, Canada, formally discussed the findings. He noted that this combination in advanced melanoma showed “limited progression-free...
First-Line Nivolumab/Ipilimumab Combination in Non–Small Cell Lung Cancer Shown to Be Tolerable
For advanced non–small cell lung cancer (NSCLC), first-line treatment with combined immune checkpoint blockade—in novel doses and schedules—was associated with deep and durable responses, encouraging progression-free survival, and much better tolerability than has been previously observed with...
Over Three-Quarters of People With Cancer Worldwide Have No Access to Safe Surgery
Over 80% of the 15 million people diagnosed with cancer worldwide in 2015 will need surgery, but less than one-quarter of them will have access to proper, safe, affordable surgical care when they need it, according to a major new Commission examining the state of global cancer surgery. The...
Cancer Incidence and Mortality Rates Worldwide
As discussed in the new series “Global Oncology Burden”, analysis of the cancer burden based on the regions as divided by the World Health Organization (WHO) (ie, Africa, the Americas, South-East Asia, Europe, Eastern Mediterranean, and Western Pacific), reveals the marked differences (see Table...
Thomas A. Stamey, MD, Noted Urologist and Prostate Cancer Expert, Dies at 87
Thomas A. Stamey, MD, Professor Emeritus of Urology at the Stanford University School of Medicine and a leader in the study and treatment of prostate cancer, died of Alzheimer’s disease September 4. He was 87. A True Pioneer in the Field Dr. Stamey helped lay the groundwork for the...
Sidney Mirvish, PhD, Carcinogenesis Researcher, Dies at 86
Sidney Mirvish, PhD, Professor Emeritus in the Eppley Institute for Research in Cancer and Allied Diseases at the University of Nebraska Medical Center (UNMC), whose pioneering research into nitrosamines and carcinogenesis led to changes in the way lunch meats, hot dogs, and sausages were made,...
Decreased Mortality in Men With Unfavorable-Risk Prostate Cancer and Moderate or Severe Comorbidities Treated With Radiotherapy Alone
Men with unfavorable-risk prostate cancer and moderate or severe comorbidities had significantly decreased overall and cardiac mortality when treated with radiotherapy alone vs radiotherapy and androgen-deprivation therapy, according to a study described in a research letter in The Journal of the...
Diagnosis of Additional Small Cancers Suggests Screening Mammography Leads to Overdiagnosis
A study of screening mammography across U.S. counties found that “the clearest result of mammography screening is the diagnosis of additional small cancers” but without a “concomitant decline in the detection of larger cancers, which might explain the absence of any significant difference in the...
Scotty’s Gift
The following essay by Emil J. Freireich, MD, is adapted from The Big Casino: America’s Best Cancer Doctors Share Their Most Powerful Stories, which was coedited by Stan Winokur, MD, and Vincent Coppola and published in May 2014. The book is available on Amazon.com and thebigcasino.org. I learned...
A Practical Guide to Surviving Breast Cancer and Its Treatments
BOOKMARK Title: Bald Is Better With Earrings: A Survivor’s Guide to Getting Through Breast CancerAuthor: Andrea HuttonPublisher: Harper CollinsPublication date: July 7, 2015Price: $17.99; paperback, 224 pages There are a plethora of books written by breast cancer survivors, and there are sure to...
Extraordinary Medical Advances and the Conundrum They Pose
BOOKMARK Title: Ordinary Medicine: Extraordinary Treatments, Longer Lives, and Where to Draw the LineAuthor: Sharon R. KaufmanPublisher: Duke University PressPublication date: May 29, 2015Price: $26.95 paperback, 336 pages Medicine has changed radically over the past 15 years. Who doesn’t welcome...
Measuring Global Health Issues, Seven Billion Times
BOOKMARK Title: Epic Measures: One Doctor. Seven Billion PatientsAuthor: Jeremy N. SmithPublisher: Harper WavePublication date: April 7, 2015Price: $26.99; hardcover, 352 pages Health measures are essential tools in assessing public health and safety. Collecting large amounts of data is a laborious ...
Melanoma Research Alliance Appoints President and CEO-Elect
The Melanoma Research Alliance (MRA) announced the appointment of Robin L. Davisson, PhD, as President and CEO-Elect, effective October 1, 2015. Dr. Davisson, The Andrew Dickson White Professor of Molecular Physiology at Cornell University, brings to MRA more than 25 years of internationally...
Lisa Kachnic, MD, Named Chair of Radiation Oncology at Vanderbilt
Lisa Kachnic, MD, former Professor and Chair of Radiation Oncology and Associate Director of Multidisciplinary Cancer Research at Boston University School of Medicine, and Chief of Radiation Oncology at Boston Medical Center, has been named Professor and Chair of the Vanderbilt University Medical...
Expect Questions About Treatment for Ductal Carcinoma in Situ
The recent study findings that women diagnosed with ductal carcinoma in situ had a low breast cancer–specific mortality and that preventing ipsilateral recurrences did not prevent breast cancer mortality1 might lead some women diagnosed with ductal carcinoma in situ to question the need for...
Varied Reactions to Study Finding That Preventing Ipsilateral Recurrence Did Not Prevent Death From Breast Cancer
Women diagnosed with ductal carcinoma in situ have a low risk of dying of breast cancer, according to an observational study looking at data from 108,196 women diagnosed with ductal carcinoma in situ between 1988 and 2011.1 The breast cancer–specific mortality rate for these women was 1.1% at 10...
Todd Demmy, MD, FACS, FCCP, Joins Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey has named Todd Demmy, MD, FACS, FCCP, as its new Chief of Thoracic Oncology and Associate Chief of the Division of Surgical Oncology. Dr. Demmy, who is leading Rutgers Cancer Institute’s Thoracic Oncology Program, is an international leader in minimally...
Recent Johns Hopkins Oncology Faculty Appointments
Nina Wagner-Johnston, MD, has been appointed Associate Professor of Oncology in the Hematologic Malignancies Division, and will lead the Lymphoma Drug Development Program. At the Siteman Cancer Center at the Washington University in St. Louis, Dr. Wagner-Johnston made several important...
2015 Oncology Meetings
OCTOBER ASTRO’s 57th Annual MeetingOctober 18-21 • San Antonio, Texas For more information: www.astro.org/Meetings-and-Events/2015-Annual-Meeting/Index.aspx 2015 International Cancer Education ConferenceOctober 21-23 • Tucson, Arizona For more information: http://2015.attendicec.org ACCC 32nd...
NIH Awards Nearly $35 Million to Research Natural Products
Five research centers will focus on the safety of natural products, how they work within the body, and the development of cutting-edge research technologies. The centers, jointly funded by the National Institutes of Health’s Office of Dietary Supplements (ODS) and the National Center for...
Children’s Hospital of Philadelphia Is a Founding Member of the New Pediatric Preclinical Testing Consortium
Addressing the relatively small number of new cancer drugs for children, a selective group of leading research centers is joining a new federally funded research consortium aimed at bringing scientific rigor and a concentrated effort to identifying new drug candidates for pediatric clinical trials. ...
A Cancer Care Model for Rural Areas
Rural cancer patients have long had to adjust to difficult geographic and financial barriers to access high-quality cancer care. These problems are exacerbated by today’s fiscal challenges, which have disrupted many of the small community practices that once served rural communities. In 2006, the...
‘Modern’ Surgical Scene, Circa 1945
A Century of Progress The text and photographs on this page are excerpted from a four-volume series of books titled Oncology Tumors & Treatment: A Photographic History, by Stanley B. Burns, MD, FACS. The photos below are from the volume titled “The Anesthesia Era: 1916–1945.” To view...
