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Your search for antibody drug conjugates matches 252 pages

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breast cancer

Biomarker Analysis Identified Women Most Likely to Benefit from T-DM1

For women with metastatic, HER2-positive breast cancer, the amount of HER2 on their tumor might determine how much they benefit from T-DMI—also now known as ado-trastuzumab emtansine (Kadcyla)—according to data from a subanalysis of the phase III clinical trial that led the FDA to...

gynecologic cancers

New Type of Experimental Drug Active in Platinum-resistant Ovarian Cancers

The antibody-drug conjugate DMUC5754A, a novel member of a relatively new class of drugs, showed activity in women with ovarian cancer, even those with hard-to-treat, platinum-resistant disease, in a phase I trial presented at the AACR Annual Meeting 2013, held in Washington, DC, April 6 to 10....

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