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Showing 15901 - 15950COMBI-d Trial and the Need to Guide Progress in Melanoma Treatment
As reviewed in this issue of The ASCO Post, Long et al1 have reported the final overall survival analysis of the COMBI-d phase III trial comparing combination therapy with the BRAF inhibitor dabrafenib (Tafinlar) and the MEK inhibitor trametinib (Mekinist) to monotherapy with dabrafenib alone,...
St. Jude Names Keith Perry, MBA, as Chief Information Officer
St. Jude Children’s Research Hospital has named Keith Perry, MBA, as Chief Information Officer (CIO) to provide strategic counsel and leadership for the hospital’s information technology initiatives. “Our internal information technology systems and operations play a critical role in the success...
Getting There From Here: What You Need to Know About Traveling to Cuba
In January 2015, the U.S. Department of the Treasury and the U.S. Department of Commerce announced changes related to the easing of sanctions on Cuba, which loosened some restrictions on travel for Americans, although some rules still apply. There are 12 legal categories of travel to Cuba,...
Resilient New Orleans: 10 Years After Katrina
It’s been 10 years since floodwaters washed away lives in New Orleans—for most, figuratively or temporarily, but for more than 1,800, literally. We who call this place home all lost something—homes, possessions, jobs, pets, loved ones, our sanity. Mold and muck marked our days for a long time, but...
State-of-the-Art Management of Germ Cell Tumors Produces High Cure Rates
Pasquale W. Benedetto, MD, the Leonard M. Miller Professor of Medicine at the University of Miami/Sylvester Comprehensive Cancer Center, recently spoke at the 2015 New Orleans Summer Cancer Meeting about his approach to diagnosing and treating germ cell tumors in men.1 The ASCO Post was there to...
NCI and Sage Bionetworks Present: Up for A Challenge?
The National Cancer Institute (NCI) Division of Cancer Control and Population Sciences is partnering with Sage Bionetworks for “Up for a Challenge (U4C): Stimulating Innovation in Breast Cancer Genetic Epidemiology.” This prize competition aims to explore the genomic basis of breast cancer in...
Coping With Aging and Cancer: Psychosocial Factors and Geriatric-Specific Interventions
You can’t control the wind, but you can adjust your sails,” said Mindy Greenstein, PhD, consulting psychologist and author, to begin her talk at the 2015 World Congress of Psycho-Oncology, held in July in Washington, DC. The sense of this proverb pervaded the entire session on cancer and aging....
Three New Officers Elected to ASTRO’s Board of Directors
The American Society for Radiation Oncology (ASTRO) has elected three new officers to the Board of Directors and three members to serve on the Nominating Committee. Terms for all positions begin on October 20, 2015 at ASTRO’s 57th Annual Meeting. The new officers to the Board of Directors are:...
IPOS Announces 2015 Award Winners at the World Congress of Psycho-Oncology
The International Psycho-Oncology Society (IPOS) announced four award winners at the 2015 World Congress of Psycho-Oncology, held July 28 to August 1 in Washington, DC. Arthur M. Sutherland Award: William H. Redd, PhD Dr. Redd is Professor of Oncological Sciences at the Mount Sinai Hospital. He is...
HPV16 DNA in Post-Treatment Oral Rinses Signals Poor Prognosis in Oropharyngeal Cancer
Detectable oral HPV16 DNA in oral rinses post treatment for oropharyngeal cancer appears to be a harbinger of poor prognosis and can predict recurrence. Oral HPV16 DNA rinses are a potential tool for long-term tumor surveillance, according to a study selected for the Best of ASCO® 2015.1 “The goal ...
Role of Surgery and Adjuvant Radiotherapy in the Treatment of Breast Cancer Explored
Two separate retrospective studies have further refined our understanding of the respective contributions of surgery and radiotherapy in the treatment of breast cancer. However, these studies are not definitive, and “gold standard” trials are needed to arrive at definitive recommendations. Both...
Indolent Lymphoma: A More Complex Malignancy Than Once Thought
With a growing number of options for follicular lymphoma, clinicians may wonder whether there is one best regimen. James O. Armitage, MD, FACP, FRCP, Professor of Medicine at the University of Nebraska, Omaha—and Editor-in-Chief of The ASCO Post—tackled this question and offered recommendations at...
Charting a New Course: From Clinical Investigator to University President
What first intrigued Fadlo R. Khuri, MD, FACP, about the prospect of becoming the 16th President of the American University of Beirut (AUB) in Lebanon was the chance to give back to an institution and a country that had given him so much. Born in Boston, Massachusetts, in 1963, Dr. Khuri was raised ...
Elotuzumab Ushers in a New Era in Myeloma Therapy
The long wait for monoclonal antibodies for the treatment of multiple myeloma is over. In the landmark ELOQUENT-2 study, reviewed in this issue of The ASCO Post, Lonial and colleagues convincingly demonstrate the effectiveness of elotuzumab, a monoclonal antibody directed against SLAMF7, in the...
Patient Guides Available Through ASCO University Bookstore
ASCO Answers: Managing the Cost of Cancer Care explains the various costs associated with cancer treatment, including health-care coverage through the Affordable Care Act. It also provides a list of financial resources available to help offset expenses related to care and tips for organizing...
Let It Be Hard
The ASCO Post is pleased to reproduce installments of the “Art of Oncology” as published previously in the Journal of Clinical Oncology (JCO). These articles focus on the experience of suffering from cancer or of caring for people diagnosed with cancer, and they include narratives, topical essays,...
Jeffrey S. Weber, MD, PhD, Joins NYU Langone and Perlmutter Cancer Center
Jeffrey S. Weber, MD, PhD, an expert in immunotherapy and melanoma, will join the senior faculty of NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center. Dr. Weber will serve as Deputy Director of the Perlmutter Cancer Center and Codirector of its Melanoma Program and will...
Internationally Acclaimed Cancer Researcher, Gianni Bonadonna, MD, Dies at 81
Gianni Bonadonna, MD, was considered the “Father of Italian Oncology,” but his scientific contributions to the field and his generous collegial spirit extended far beyond the shores of his native land. Dr. Bonadonna was at the forefront in the battle to convince the surgical establishment that...
In Search of a Good Ending for a Life Well Lived
BOOKMARK Title: The Conversation: A Revolutionary Plan for End-of-life CareAuthor: Angelo E. Volandes, MDPublisher: BloomsburyPublication date: January 13, 2015Price: $26.00; hardcover, 240 pages A quick Google search on books about end-of-life care will yield pages of hits on the subject. The...
An Unvarnished, Behind-the-Scenes Look at the Hospital Nurse
BOOKMARK Title: The Nurses: A Year of Secrets, Drama, and Miracles With the Heroes of the HospitalAuthor: Alexandra RobbinsPublisher: Workman Publishing CompanyPublication date: April 14, 20155Price: $17.53; hardcover, 368 pages Florence Nightingale, the most famous and influential figure in...
2015 Oncology Meetings
OCTOBER Advances in Cancer ImmunotherapyTMOctober 2 • Nashville, Tennessee For more information: www.sitcancer.org/sitc-meetings/aci2015/tn Institute for Clinical Immuno-Oncology (ICLIO) 1st Annual National ConferenceOctober 2 • Philadelphia, Pennsylvania For more information:...
Microbes by the Trillions
BOOKMARK Title: 10% Human: How Your Body’s Microbes Hold the Key to Health and HappinessAuthor: Alanna CollenPublisher: Harper CollinsPublication date: April 27, 2015Price: $39.99; hardcover, 400 pages "As I walked back through the forest that night in the summer of 2005, with twenty bats in...
MD Anderson Names Valerae O. Lewis, MD, Chair of Orthopaedic Oncology
Valerae O. Lewis, MD, has been named Chair of Orthopaedic Oncology at The University of Texas MD Anderson Cancer Center. Dr. Lewis has been a faculty member at MD Anderson for 15 years, serving in a variety of roles. The unit she will lead, the Department of Orthopaedic Oncology, is a new...
Updated Analysis of Menopausal Hormone Therapy and Breast Cancer Risk
As reviewed in this issue of The ASCO Post, Chlebowski and colleagues1 reported differing patterns of breast cancer risk during or after hormonal therapy with estrogen plus progestin2 or estrogen alone,3 in an analysis of two Women’s Health Initiative (WHI) trials. This recent update on risk...
NCI Awards Huntsman Cancer Institute, University of New Mexico Cancer Center Comprehensive Cancer Center Designations
The National Cancer Institute (NCI) recently awarded Huntsman Cancer Institute (HCI) at the University of Utah and The UNM Cancer Center (UNMCC) at the University of New Mexico Comprehensive Cancer Center status. An NCI-Designated Comprehensive Cancer Center must demonstrate depth and breadth of...
FDA Accepts for Priority Review the Biologics License Application for Elotuzumab for the Treatment of Relapsed Multiple Myeloma
Bristol-Myers Squibb and AbbVie recently announced that the U.S. Food and Drug Administration has accepted for priority review the Biologics License Application for elotuzumab, an investigational signaling lymphocyte activation molecule (SLAMF7)-directed immunostimulatory antibody, for the...
FDA Grants Regular Approval to Brentuximab Vedotin in High-Risk Classical Hodgkin Lymphoma
The U.S. Food and Drug Administration has approved brentuximab vedotin (Adcetris) as post–autologous hematopoietic stem cell transplantation consolidation treatment for patients with classical Hodgkin lymphoma at high risk of relapse or progression, Seattle Genetics has announced. The approval is...
ASCO University® Releases 2015 Curricula for Advanced Practice Providers (ACAPP™)
ASCO University has released an updated version of ASCO’s Curricula for Advanced Practice Providers (ACAPP™). This popular series assists with the orientation of advanced practice providers (APPs) into oncology practices—a growing need as increasing numbers of APPs are hired to meet the demand for...
Lurie Cancer Center Receives $11.7 Million NCI Grant to Improve Treatment Using Nanotechnology
Northwestern University has received a 5-year, $11.7 million grant from the National Cancer Institute (NCI) to use nanotechnology to develop next-generation cancer treatments. With NCI support, the new Northwestern University Center for Cancer Nanotechnology Excellence (Northwestern CCNE) will use...
Barbara Pro, MD, Joins the Lurie Cancer Center
The Robert H. Lurie Comprehensive Cancer Center of Northwestern University announced the addition of medical oncologist Barbara Pro, MD. A leader in the research and treatment of lymphomas, Dr. Pro joined the Lurie Cancer Center in September 2015. She has been appointed Professor of Medicine in...
FDA Approves Rolapitant for Prevention of Chemotherapy-Induced Nausea and Vomiting
The U.S. Food and Drug Administration (FDA) approved rolapitant (Varubi) to prevent delayed-phase chemotherapy-induced nausea and vomiting. Rolapitant is approved in adults in combination with other antiemetic agents that prevent nausea and vomiting associated with initial and repeat courses of...
ASTRO Awards Seven Physician-Researchers $675,000 in Grants for Radiation Oncology Research
The American Society for Radiation Oncology (ASTRO) has selected seven leading physician-researchers to receive a total of $675,000 in awards and grants to advance radiation oncology research. Together, the grants will support studies in cancer biology, radiation physics, translational research,...
Carl H. June, MD, Awarded the 2015 Watanabe Prize
Carl H. June, MD, an internationally recognized leader in the growing field of immunotherapy, was awarded the Watanabe Prize at the 7th Annual Meeting of the Indiana Clinical and Translational Sciences Institute (CTSI) on September 11 on the campus of Indiana University–Purdue University...
Texas Center for Proton Therapy Names Chang Chang, PhD, Director of Physics
Chang Chang, PhD, a leader in proton therapy medical physics, has been named Director of Physics at Texas Center for Proton Therapy. Previously, as Senior Medical Physicist at ProCure Proton Therapy Center in Somerset, New Jersey, Dr. Chang was involved in the commissioning of new proton technology ...
2015 ASTRO Gold Medal Recipients Announced
The American Society for Radiation Oncology (ASTRO) has chosen three radiation oncology physicians and researchers to receive the 2015 ASTRO Gold Medal: Carl R. Bogardus, Jr, MD, FASTRO; Carl M. Mansfield, MD, ScD (Hon), FASTRO; and James B. Mitchell, PhD, FASTRO. Drs. Bogardus, Mansfield, and...
Tari King, MD, Named Chief of Breast Surgical Services at Dana-Farber/Brigham and Women’s Cancer Center
Tari King, MD, has been appointed Chief of Breast Surgery at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC). Dr. King will hold appointments at Brigham and Women’s Hospital, Faulkner Hospital, and Dana-Farber Cancer Institute. Dr. King will oversee breast surgery in the DF/BWCC, which...
One Doctor’s Road to Palliative Care Services in the Inner City
St. Barnabas Hospital is located in the heart of Bronx, New York, and as such, it has a culturally diverse, largely poor, patient population. The backbone of successful palliative care services is the doctor-patient communication bonding process. However, many of the patients with late-stage cancer ...
James P. Allison, PhD, Wins Clinical Medical Research Lasker-DeBakey Award
James P. Allison, PhD, Chair of Immunology at The University of Texas MD Anderson Cancer Center, has been named the 2015 winner of the Lasker-DeBakey Clinical Medical Research Award from the Albert and Mary Lasker Foundation. The Lasker awards, in their 70th year, honor major achievements in basic...
For Big Data Projects, Bigger Is Better
In an interview with The ASCO Post, Robert S. Miller, MD, FACP, Senior Director, Quality and Guidelines, ASCO, and Medical Director, CancerLinQ™, described how the system could work with data specific to radiation oncology. “The system is in the rapid build phase now, what we are calling the...
Yale Cancer Center Receives $11 Million SPORE Grant for Lung Cancer Research
The National Cancer Institute (NCI) recently awarded Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven a Specialized Program of Research Excellence, or SPORE, grant worth $11 million. The Yale SPORE will launch a new research program in non–small cell lung cancer. The new research...
NCI Awards SPORE Grant to Mayo Clinic Multiple Myeloma Research Team
A team of Mayo Clinic Cancer Center scientists has been awarded a Specialized Program of Research Excellence (SPORE) grant in multiple myeloma from the National Cancer Institute. The Center is one of only three cancer centers to receive a SPORE grant for multiple myeloma cancer research. “With...
Jinghui Zhang, PhD, Named Chair of Computational Biology at St. Jude
St. Jude Children’s Research Hospital has named Jinghui Zhang, PhD, as the first Chair of the Department of Computational Biology. She will hold the St. Jude Endowed Chair in Bioinformatics. Computational biology applies mathematics and computer science to the study of genomics, systems biology,...
Fred R. Hirsch, MD, PhD, Presented With 2015 Addario Lectureship Award
The Bonnie J. Addario Lung Cancer Foundation (ALCF) honored Fred R. Hirsch, MD, PhD, with the 2015 Addario Lectureship Award for his continued leadership and expertise in lung cancer treatment and research. Dr. Hirsch, CEO of the International Association for the Study of Lung Cancer (IASLC),...
ASH Honors John C. Byrd, MD, With 2015 William Dameshek Prize
The American Society of Hematology (ASH) will present the 2015 William Dameshek Prize to John C. Byrd, MD, of The Ohio State University Comprehensive Cancer Center–Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) for his contributions to the development of...
Mantle Cell Lymphoma: Is Transplantation Still Necessary?
Autologous stem cell transplantation has played a critical role in the treatment of mantle cell lymphoma, but in the age of novel treatments, is it always warranted? Two experts in the field explored the question at the 2015 Debates and Didactics in Hematology and Oncology Conference sponsored by...
Making Their Voices Heard: 118 Oncologists Speak Out About Stemming the High Cost of Cancer Drugs
In a bold move to shed light on the ramifications of the ever-increasing cost of cancer drugs for patients with cancer and for the health-care system, 118 prominent oncologists came together to write a commentary in Mayo Clinic Proceedings detailing their concerns.1 To learn more about these...
First-Line Nivolumab/Ipilimumab Combination in Non–Small Cell Lung Cancer Shown to Be Tolerable
For advanced non–small cell lung cancer (NSCLC), first-line treatment with combined immune checkpoint blockade—in novel doses and schedules—was associated with deep and durable responses, encouraging progression-free survival, and much better tolerability than has been previously observed with...
Over Three-Quarters of People With Cancer Worldwide Have No Access to Safe Surgery
Over 80% of the 15 million people diagnosed with cancer worldwide in 2015 will need surgery, but less than one-quarter of them will have access to proper, safe, affordable surgical care when they need it, according to a major new Commission examining the state of global cancer surgery. The...
Cancer Incidence and Mortality Rates Worldwide
As discussed in the new series “Global Oncology Burden”, analysis of the cancer burden based on the regions as divided by the World Health Organization (WHO) (ie, Africa, the Americas, South-East Asia, Europe, Eastern Mediterranean, and Western Pacific), reveals the marked differences (see Table...
Thomas A. Stamey, MD, Noted Urologist and Prostate Cancer Expert, Dies at 87
Thomas A. Stamey, MD, Professor Emeritus of Urology at the Stanford University School of Medicine and a leader in the study and treatment of prostate cancer, died of Alzheimer’s disease September 4. He was 87. A True Pioneer in the Field Dr. Stamey helped lay the groundwork for the...
