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Issues in Oncology
Survivorship

Proposed Categories of Cancer Survivors Aim to Bring Survivorship Into Precision Medicine Era

Care for people who have survived or are living with cancer should acknowledge the heterogeneity of their needs and experiences and should reflect the same level of personalization that is now guiding active cancer therapy. At a time when more people are surviving cancer than ever before, new...

Head and Neck Cancer
Survivorship

Optimizing Quality of Life in Head and Neck Cancer Survivors

Head and neck cancer can take away a patient’s “right to feel human,” and its impact on physical appearance, physical functioning, and general quality of life can be devastating, according to Merry Sebelik, MD, Associate Professor of Head and Neck Surgery at Emory University in Atlanta. At a...

breast cancer
survivorship

Matteo Lambertini, MD, on Pregnancy in Breast Cancer Patients: Results From a Multicenter Study

Matteo Lambertini, MD, of the Institut Jules Bordet, discusses a long-term follow-up analysis of the safety of pregnancy in patients with a history of estrogen receptor–positive breast cancer. (Abstract LBA10066)

survivorship

Todd M. Gibson, PhD, on Childhood Cancer Survivors: Chronic Disease Trends

Todd M. Gibson, PhD, of St. Jude Children’s Research Hospital, discusses results from the Childhood Cancer Survivor Study, which showed a reduction in serious chronic morbidity measured across 3 decades. (LBA10500)

breast cancer
survivorship

ASCO 2017: Pregnancy After Breast Cancer Does Not Increase Chance of Recurrence

Findings from a retrospective study of 1,200 women provide reassurance to breast cancer survivors who are contemplating pregnancy. In the study, women who became pregnant after an early breast cancer diagnosis, including those with estrogen receptor–positive tumors, did not have a higher...

solid tumors
survivorship

ASCO 2017: Low Testosterone Level After Testicular Cancer Is Common, Linked to Chronic Health Problems

In a large study, 38% of 491 testicular cancer survivors had low testosterone levels. Compared with survivors with normal testosterone levels, survivors with low testosterone levels were more likely to have a range of chronic health problems, including high blood pressure, diabetes, erectile...

survivorship

ASCO 2017: Steady Decrease in Severe Health Problems for Childhood Cancer Survivors

Treatments for childhood cancer are often intense and carry the risk of lifelong health problems for survivors. An analysis of 23,600 childhood cancer survivors in the Childhood Cancer Survivor Study (CCSS), funded by the National Institutes of Health, found that the rate of severe health problems...

Survivorship

Celebrating Cancer Survivorship

Sunday, June 4, 2017, marks the 30th anniversary of National Cancer Survivors Day. Here’s a look at the progress that has been made over the past 2 to 3 decades in reducing cancer incidence and cancer deaths and the challenges that remain. Increasing Rates of Cancer Survivorship In 1971, the...

Survivorship

Distinguished Pediatric Oncologist Anna T. Meadows, MD, Led the Way for Studies in Childhood Cancer Survivors

Anna T. Meadows, MD, an internationally distinguished pediatric oncologist who led paradigm-changing survivorship research and clinical care of children with cancer, had an unusual introduction to the United States. “My mother was traveling abroad on vacation and got married in Poland. Although...

Survivorship
Lung Cancer

Precision Medicine and My Own Activism Are Keeping Me Alive

In 2009, I was living my dream. My work as a business development manager for a technology company was thriving; I had a satisfying social life; I was active in sports, especially hiking and biking; and I was involved in social justice causes as a volunteer at San Quentin State Prison, helping...

Survivorship
Colorectal Cancer

Expert Point of View: Patrick S. Sullivan, MD

”This was a great study and novel, asking what longer-term survivors with colon cancer are dying from—the toxicity of our treatment or population-risk illnesses?” commented session co-moderator, Patrick S. Sullivan, MD, Assistant Professor of Surgery and Chief Quality Officer, Division of Surgical ...

Survivorship
Colorectal Cancer

Common Causes of Death Predominate Among Long-Term Colorectal Cancer Survivors

Patients with colorectal cancer who survive at least 5 years are increasingly likely to die from causes that are common in the general population, highlighting the importance of screening and lifestyle modification, suggested a large cohort study conducted in California.1 The analysis of more than...

survivorship
cost of care

Economic Impact of Chronic Conditions on Cancer Survivors

There is a higher prevalence of chronic health conditions among cancer survivors vs people without a history of cancer, and the presence of chronic conditions is associated with greater annual medical expenditures compared with the absence of such conditions in cancer survivors. These findings were ...

survivorship

Blended Cognitive Behavior Therapy and Fear of Recurrence in Cancer Survivors

A Dutch study (SWORD) has shown that blended cognitive behavioral therapy (CBT)—mixing face-to-face and online sessions—reduced the fear of recurrence among survivors of breast, prostate, and colorectal cancers. These results were reported by van de Wal et al in the Journal of Clinical...

gynecologic cancer
survivorship

ESTRO 2017: Cervical Cancer Survivors Frequently Suffer From Long-Term Fatigue, Insomnia, and Hot Flashes

Around half of women who have been treated for locally advanced cervical cancer suffer from symptoms of insomnia, fatigue, or hot flashes at some point, according to new research presented at the European Society for Radiotherapy & Oncology (ESTRO) 36 Conference (Abstract OC-0051). Cervical...

Survivorship

Cardiac Dysfunction in Survivors of Adult Cancers

The success of cancer therapy has led us to an interesting place. Patients with cancer are certainly concerned about collateral damage that may occur with the treatment of their condition; however, impressive improvements in survival with treatment of many cancers are so compelling that these...

Survivorship

ASCO Clinical Practice Guideline on Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers

As reported in the Journal of Clinical Oncology by Saro H. Armenian, DO, MPH, of City of Hope, and colleagues, ASCO has released a clinical practice guideline on prevention and monitoring of cardiac dysfunction in survivors of adult cancers.1 Recommendations were developed by an expert panel...

Breast Cancer
Survivorship

Online Symptom-Management Curriculum May Improve Depression and Fatigue in Breast Cancer Survivors

With thousands of devices to track and manage health and wellness, eHealth tools are beginning to transform modern health care and research, demonstrating quantifiable improvements in patient outcomes. According to the results of a randomized controlled trial (Reimagine), breast cancer survivors...

Breast Cancer
Symptom Management
Survivorship

Expert Point of View: Ann H. Partridge MD, MPH

Ann H. Partridge MD, MPH, Director of Adult Cancer Survivorship Program at the Dana-Farber Cancer Institute, praised the “tremendous work” of Dr. Paskett and her colleagues but referred to the findings as “disappointing to say the least.”1 “Developing interventions to prevent or treat lymphedema...

Breast Cancer
Symptom Management
Survivorship

Search Continues for Effective Way to Prevent Lymphedema in Breast Cancer Survivors

There was no difference in the incidence of lymphedema at 18 months in breast cancer patients randomized to a physical therapy intervention with education materials compared with a control.1 Although poor adherence to the intervention may have been a factor, these results, described as “very...

Solid Tumors
Survivorship

Expert Point of View: Kevin C. Oeffinger, MD

Kevin C. Oeffinger, MD, Director of the Adult Long-Term Follow-up Program at Memorial Sloan Kettering Cancer Center, New York, highlighted the typical fat distribution of this population while noting the limitations of standard criteria for metabolic syndrome, which include waist circumference....

Solid Tumors
Survivorship

Platinum Study Finds High Risk of Metabolic Syndrome in Testicular Cancer Survivors

A multicenter study of North American testicular cancer survivors treated with platinum-based chemotherapy has found a high prevalence of metabolic syndrome, a cluster of cardiovascular risk factors that doubles the risk of cardiovascular disease.1 According to the results of this trial,...

Survivorship

Building a Multidisciplinary Model of Care for Cancer Survivors

Last year’s inaugural Cancer Survivorship Symposium stressed the importance of bringing together the fields of medical oncology and primary care to ensure a coordinated effort to help patients with cancer transition to long-term survivorship care. Building on that goal, the 2017 Cancer Survivorship ...

survivorship

Risk of Adverse Health Outcomes in Testicular Cancer Survivors After Cisplatin-Based Chemotherapy

In a study reported in the Journal of Clinical Oncology, Fung et al found that although adverse health outcomes were common among testicular cancer survivors, there did not appear to be differences in such outcomes according to chemotherapy regimens commonly used to treat favorable-risk disease....

survivorship

Decreasing but Still Elevated Risk for Subsequent Neoplasms in Survivors of Childhood Cancers

In a retrospective multicenter cohort study reported in JAMA, Turcotte et al found that the risk for subsequent neoplasms in 5-year survivors of childhood cancers decreased between those diagnosed in the 1970s vs the 1990s but nevertheless remained elevated vs expected incidence. The reduced risk...

Survivorship

How Stupid Cancer Is Building a Support Community for AYA Survivors

In 1995, Matthew Zachary, an aspiring concert pianist and composer, was en route to graduate school to study film composition when he lost all fine-motor coordination in his left hand, was diagnosed with pediatric brain cancer (medulloblastoma), told he would never play again, and was given 6...

breast cancer
survivorship

Nicole Mittmann, PhD, on Breast Cancer Well Follow-up

Nicole Mittmann, PhD, of the Sunnybrook Health Sciences Centre, discusses her study findings on transitioning breast cancer survivors to primary care and the savings in resources and dollars that accrued as a result (Abstract 1).

Issues in Oncology
Survivorship

Update on Fertility Outcomes Among Survivors of Childhood Cancer

“Estimates suggest that by the year 2020, there will be over 500,000 adult survivors of childhood cancer in the United States,” Daniel A. Mulrooney, MD, MS, of the Division of Cancer Survivorship, St. Jude Children’s Research Hospital, Memphis, reported at the 10th Oncofertility Conference in...

Issues in Oncology
Survivorship

Many Cancer Survivors Find Online and Telephone Communication With Health-Care Professionals Beneficial

Researchers from the School of Health Sciences at the University of Surrey, Guildford, United Kingdom, have completed the first-ever systematic review of cancer survivors’ experience of online and telephone telehealth interventions in cancer care, according to a recent study reported by Anna Cox,...

Survivorship
Health-Care Policy

Timing Is Everything

In 1959, my 5-year-old cousin, Kim, was diagnosed with acute lymphocytic leukemia (ALL). As an 8-year-old, I didn’t really understand what was happening to him, except that he had to go to the Riley Hospital for Children in Indianapolis, Indiana, for treatment. The haunting vision of his looking...

survivorship

Cancer Survivors Find Online and Telephone Communication With Health-Care Professionals Beneficial

Researchers from the School of Health Sciences at the University of Surrey have completed the first-ever systematic review of cancer survivors’ experience of online and telephone telehealth interventions in cancer care, a new study by Cox et al in the Journal of Medical Internet...

geriatric oncology
survivorship

Arti Hurria, MD, on Senior Citizens: Living Through and Beyond Cancer

Arti Hurria, MD, of City of Hope, discusses the assessment of older patients with cancer.

survivorship

Allison Harvey, MPH, CHES, on Teaching Providers About Survivorship

Allison Harvey, MPH, CHES, of George Washington University, evaluates preliminary outcomes among primary care and oncology providers who took part in the Cancer Survivorship E-Learning Series (Abstract 78).

breast cancer
survivorship

Shoshana M. Rosenberg, ScD, MPH, on Young Breast Cancer Survivors: Helping Them Cope

Shoshana M. Rosenberg, ScD, MPH, of the Dana-Farber Cancer Institute, talks about ways to help young women move from active treatment to survivorship, based on findings from focus groups in which patients discussed their unexpected physical and psychological experiences after surgery (Abstract 180).

breast cancer
survivorship

Lauren P. Wallner, PhD, MPH, on Breast Cancer Survivorship Care: Patient Preferences

Lauren P. Wallner, PhD, MPH, of the University of Michigan, discusses her findings on the type of providers women prefer when it comes to handling survivorship care after breast cancer treatment and the need to clarify and discuss provider roles with patients (Abstract 99).

survivorship
pain management
breast cancer

Sophia Kustas Smith, PhD, MSW, on Depression and Fatigue: Self-Managed in 'Reimagine'

Sophia Kustas Smith, PhD, MSW, of Duke University, discusses study findings on an online, symptom self-management curriculum, known as www.reimagine.me, employed for breast cancer survivors with chronic pain (Abstract 182).

survivorship

Ann H. Partridge, MD, MPH, on Adolescent and Young Adult Patients: Their Survivorship Challenges

Ann H. Partridge, MD, MPH, of the Dana-Farber Cancer Institute, summarizes a session she co-chaired on the unique issues affecting adolescent and young adult patients, including their psychosocial needs and concerns that clinicians may overlook.

thyroid cancer
survivorship

Dong Wook Shin, MD, DrPH, MBA, on Thyroid Cancer: Risk of Side Effects

Dong Wook Shin, MD, DrPH, MBA, of Seoul National University Cancer Hospital, discusses the risk of coronary heart disease and ischemic stroke in patients with thyroid cancer taking levothyroxine (Abstract 105).

solid tumors
survivorship

Mohammad Abu Zaid, MD, on Testicular Cancer: Study Results on Metabolic Syndrome

Mohammad Abu Zaid, MD, of Indiana University Simon Cancer Center, discusses findings from a multicenter study of North American testicular cancer survivors, their prevalence of hypertension, risk factors for metabolic syndrome, and the need for screening and treatment (Abstract 102).

survivorship

Emily S. Tonorezos, MD, on Childhood Cancer Survivors and Late-Occurring Effects

Emily S. Tonorezos, MD, of Memorial Sloan Kettering Cancer Center, discusses childhood cancer survivors and the protection from late-occurring anthracycline-related cardiotoxicity conferred by a RARG coding variant.

survivorship

K. Holly Mead, PhD, on Identifying Models of Cancer Survivorship Care

K. Holly Mead, PhD, of George Washington University, discusses specialized survivorship-specific programs, which are gaining prominence, with over 40% of cancer centers in her study providing this type of care (Abstract 1).

breast cancer
survivorship

Shawna V. Hudson, PhD, on Breast Cancer: A Quality-of-Life Program

Shawna V. Hudson, PhD, of Rutgers University, discusses a survivorship program designed to improve the quality of life for Hispanic and Latino breast cancer survivors (Abstract 183).

survivorship

Health-Related Quality of Life After Cancer Diagnosis in Adolescents/Young Adults

In a longitudinal study reported in the Journal of Clinical Oncology, Husson et al found that health-related quality of life improved between diagnosis and 2 years after diagnosis in adolescent/young adult (AYA) patients with cancer, but it remained impaired compared with population norms. Study...

survivorship

How Common Is Cognitive Impairment After Chemotherapy in Breast Cancer Survivors?

In a prospective longitudinal study reported in the Journal of Clinical Oncology, Janelsins et al found that nearly half of women with breast cancer reported a clinically significant decline in cognitive function from before to after chemotherapy, compared with only 10% of age-matched noncancer...

Survivorship

As We Strive for a Cancer Cure, We Must Not Forget the Survivors

Although a cure for cancer remains elusive, there are many promising ideas to eradicate this disease, including the Cancer Moonshot Initiative and an ever-increasing body of cancer research that continually drives innovative treatments in an effort to improve survival and, ultimately, find a...

survivorship

ASCO Clinical Practice Guideline on Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers

As reported in the Journal of Clinical Oncology by Saro H. Armenian, DO, MPH, of City of Hope, and colleagues, ASCO has released a clinical practice guideline on prevention and monitoring of cardiac dysfunction in survivors of adult cancers. Recommendations were developed by an expert panel using a ...

breast cancer
survivorship

Dawn Hershman, MD, on Breast Cancer Survivorship: Poster Discussion

Dawn Hershman, MD, of the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center, reviews findings on survivorship care plans, interventions to reduce chemotherapy-induced peripheral neuropathy, and the cardiac effects of aromatase inhibitors (Poster Discussion 4).

Survivorship

Integrating AYA Oncology Care Into the Worlds of Pediatric and Adult Oncology Care to Improve Cancer Outcomes

GUEST EDITORAdolescent and Young Adult Oncology explores the unique physical, psychosocial, social, emotional, sexual, and financial challenges adolescents and young adults with cancer face. The column is guest edited by Brandon M. Hayes-Lattin, MD, FACP, Associate Professor of Medicine and...

leukemia
survivorship

Smita Bhatia, MD, MPH, and Jessica Wu, BA, on CML: A Report From the Bone Marrow Transplant Survivor Study

Smita Bhatia, MD, MPH, and Jessica Wu, BA, both of the University of Alabama at Birmingham, discuss long-term morbidity and mortality experienced by chronic myeloid leukemia patients after allogeneic hematopoietic cell transplantation (Abstract 823).

breast cancer
issues in oncology
survivorship

Psychotropic and Opioid Medication Use in Older Patients With Breast Cancer Across the Care Trajectory

A new McGill University study published by Syrowatka et al in JNCCN – Journal of the National Comprehensive Cancer Network found that most patients with breast cancer aged 65 and older use psychotropic and opioid medications during active treatment, often in the first year of...

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