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breast cancer
issues in oncology

Digital Breast Tomosynthesis Reduces Breast Cancer Screening Recall Rate Compared to Mammography Alone

The addition of tomosynthesis to standard digital mammography resulted in a 30% reduction in overall recall rates among women being screened for breast cancer, according to a new study published online in Radiology. The results demonstrate that digital tomosynthesis is an effective tool in reducing ...

lung cancer
issues in oncology

U.S. Preventive Services Task Force Recommends Screening for Lung Cancer in High-risk Individuals

The U.S. Preventive Services Task Force posted its final evidence report and draft recommendation statement on screening for lung cancer. The Task Force is providing an opportunity for public comment on this draft recommendation statement; comments can be submitted from July 30 to August ...

lung cancer

Particulate Matter Air Pollution Contributes to Increased Risk of Lung Cancer in Europe

Ambient air pollution has been associated with lung cancer risk. In a study reported in Lancet Oncology by Ole Raaschou-Nielsen, PhD, of the Danish Cancer Society Research Center, and colleagues, lung cancer incidence in European countries was prospectively assessed according to several measures of ...

gynecologic cancers
head and neck cancer
issues in oncology

CDC Report Shows Stagnated HPV Vaccination Rate for Girls

For the first time since the human papillomavirus (HPV) vaccine became available for adolescent girls in 2006, the vaccination rate for the teenagers has stalled, according to data published in the Centers for Disease Control and Prevention’s (CDC’s) Morbidity and Mortality Weekly...

lung cancer
issues in oncology

National Lung Screening Trial Analysis Supports Risk-based Targeting of Smokers for Low-dose CT Screening

The National Lung Screening Trial (NLST) showed that screening with low-dose computed tomography (CT) resulted in a 20% reduction in lung cancer mortality compared with chest radiography in participants aged 55 to 74 years with a minimum of 30 pack-years of smoking and no more than 15 years since...

gynecologic cancers
head and neck cancer
issues in oncology

HPV Vaccine Reduces Prevalence of Oral HPV Infections in Costa Rican Study

A new study by the International Agency for Research on Cancer (IARC), in partnership with Costa Rican investigators and the National Cancer Institute (NCI), shows for the first time that the vaccine against human papillomavirus (HPV) types 16 and 18, which is used to prevent cervical cancer, also...

breast cancer
issues in oncology

ASCO Releases Updated Guideline on Interventions for Women at Increased Risk for Breast Cancer

The American Society of Clinical Oncology (ASCO) issued a newly updated clinical practice guideline today on pharmacologic prevention interventions for premenopausal and postmenopausal women who are at increased risk for breast cancer. Compared to the previous version of the guideline, this third...

issues in oncology
gastroesophageal cancer

Aspirin May Help Prevent Cancer in Patients with Barrett’s Esophagus

Although aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to reduce cancer mortality by 20%, exactly why these drugs reduce the number of cancer incidences and deaths is not known. Now, a small longitudinal study of 13 patients with Barrett’s esophagus is...

colorectal cancer
issues in oncology

Volumetric Growth Rate of Small Colorectal Polyps on CT Colonography May Be Useful Risk Marker

The growth rates and clinical importance of small colorectal polyps have not been well established. In a study reported in Lancet Oncology, Perry J. Pickhardt, MD, of the University of Wisconsin School of Medicine and Public Health, and colleagues found that volumetric growth rate on computed...

issues in oncology

WHO Tobacco Control Policies Estimated to Prevent 7.4 Million Premature Deaths by 2050

Tobacco control measures put in place in 41 countries between 2007 and 2010 are predicted to prevent an estimated 7.4 million premature deaths by 2050, according to a study published in the July issue of the Bulletin of the World Health Organization. The study is one of the first to ...

lymphoma

Survival Rates for Patients with Burkitt’s Lymphoma Improve, Especially among Young Adults

Although Burkitt’s lymphoma remains one of the most highly aggressive forms of B-cell non-Hodgkin lymphoma and is associated with human immunodeficiency virus (HIV) infection, a recent study published in Blood has found a marked improvement in patient survival over the past decade, especially ...

colorectal cancer

BRAF Mutation Status May Have Effect on Benefit of Aspirin Use for Patients with Colorectal Cancer

In two large studies, the association between aspirin use and risk of colorectal cancer was affected by BRAF mutation status, with regular aspirin use associated with a lower risk of BRAF wild-type colorectal cancer but not with risk of BRAF-mutated cancer. The findings, published today in JAMA,...

prostate cancer

Use of Advanced Treatment Technologies Increases among Men at Low Risk of Dying from Prostate Cancer

Use of advanced treatment technologies for prostate cancer, such as intensity-modulated radiotherapy (IMRT) and robotic prostatectomy, has increased among men with low-risk disease, high risk of noncancer mortality, or both, a population of patients who are unlikely to benefit from these...

issues in oncology

New Study Finds AICR Recommendations Cut Breast Cancer Risk

Postmenopausal women who follow at least five Recommendations for Cancer Prevention from the American Institute for Cancer Research (AICR) cut their risk of developing breast cancer by more than half, compared to those who meet none, suggests a new study that adds to previous research showing...

issues in oncology

ASCO 2013: Top Five Things Oncologists Need to Know about Cancer in Older Adults

A workforce shortage of geriatricians and other health professionals trained and certified in caring for older patients with cancer is colliding with the aging of the population and the increasing number of older Americans with cancer. After describing factors contributing to these dual challenges, ...

breast cancer

Some Stage II/III HER2-positive Tumors May Be Treated with Targeted Therapy without Chemotherapy

Results from a multicenter phase II study of patients with locally advanced HER2-positive breast cancer who receive targeted therapy with trastuzumab (Herceptin) and lapatinib (Tykerb) “support the hypothesis that selected patients with HER2-positive tumors may not need...

breast cancer

ASCO 2013: Weekly Paclitaxel Is Less Toxic but as Effective for Women with Higher-risk Early-stage Breast Cancer

Low-dose weekly administration of paclitaxel resulted in equal progression-free survival but reduced overall toxicity compared to every-2-week dose-dense administration for women with higher-risk early-stage breast cancer who have undergone surgery, according to a phase III randomized trial....

gynecologic cancers
issues in oncology

ASCO 2013: Cervical Cancer Screening Using Visual Inspection with Vinegar Reduces Mortality by 31% in Large Study in India

Cervical cancer mortality was reduced by 31% over a period of 15 years among women screened with biennial visual inspection with acetic acid (VIA), or vinegar, delivered by primary health workers in a large randomized study conducted among 150,000 women in India. The researchers estimate this...

issues in oncology

ASCO 2013: Most U.S. Oncologists Report High Career Satisfaction, but Many Suffer Symptoms of Burnout

Although a majority of U.S. oncologists report satisfaction with their careers, many say they have experienced at least one symptom of burnout, according to a Mayo Clinic–led study released during the ASCO 2013 Annual Meeting (Abstract 6533). “Oncology can be a tremendously rewarding...

breast cancer

ASCO 2013: Everolimus Significantly Delays Tumor Growth in Women with HER2-positive Advanced Breast Cancer

The addition of everolimus (Afinitor), an mTOR inhibitor, to trastuzumab (Herceptin) and vinorelbine significantly extended progression-free survival in women with HER2-positive advanced breast cancer, compared to treatment with placebo plus trastuzumab and vinorelbine, in the phase III BOLERO-3...

breast cancer

New Method to Test Breast Lesions Could Better Detect Cancer and Reduce Repeat Biopsies

A newly developed, single-step Raman spectroscopy algorithm has the potential to simultaneously detect microcalcifications and enable diagnosis of the associated breast lesions with high precision, according to data published in Cancer Research, a journal of the American Association for Cancer...

colorectal cancer

Women Smokers May Have Greater Risk for Colon Cancer Than Men

Smoking increased the risk for developing colon cancer, and female smokers may have a greater risk than male smokers, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research. “Globally, during the last 50...

breast cancer
survivorship

Few Breast Cancer Survivors Maintain Adequate Physical Activity Despite Benefits

Breast cancer survivors are among the women who could most benefit from regular physical activity, yet few meet national exercise recommendations during the 10 years after being diagnosed, according to a study by researchers at Fred Hutchinson Cancer Research Center. Prior studies and available...

breast cancer
issues in oncology

Mammogram Tool Improves Some Breast Cancer Detection but Also Increases False Alarms

A costly and widely used mammography add-on increases detection of noninvasive and early-stage invasive breast cancer but also makes more mistakes than mammography alone, researchers from UC Davis and the University of Washington have found. A new study shows that computer-assisted detection (CAD) ...

lung cancer

Asbestos Exposure, Asbestosis, and Smoking Combined Greatly Increase Lung Cancer Risk

The chances of developing lung cancer associated with asbestos exposure, asbestosis, and smoking are dramatically increased when these three risk factors are combined, and quitting smoking significantly reduces the risk of developing lung cancer after long-term asbestos exposure, according to a new ...

breast cancer

Alcohol Consumption Has No Impact on Breast Cancer Survival, According to New Research

Although previous research has linked alcohol consumption to an increased risk of developing breast cancer, a new study has found that drinking before and after diagnosis does not impact survival from the disease. In fact, a modest survival benefit was found in women who were moderate drinkers...

supportive care

Antidepressant Helps Relieve Pain from Chemotherapy, Study Finds

The antidepressant drug duloxetine (Cymbalta) helped relieve painful numbness and tingling feelings caused by chemotherapy in 59% of patients, a new study finds. This is the first clinical trial to find an effective treatment for this pain. Chemotherapy-induced peripheral neuropathy is a common...

lung cancer

Higher Soy Intake Prior to Lung Cancer Diagnosis Linked to Longer Survival in Chinese Women

New results from a large observational follow-up study conducted in Shanghai, China, indicate that women with lung cancer who consumed more soy food prior to their cancer diagnosis lived longer than those who consumed less soy. The study, published March 25 in the Journal of Clinical Oncology,...

myelodysplastic syndromes

Moffitt Cancer Center Researchers Study Use of Dasatinib for Patients with High-risk MDS

Researchers at Moffitt Cancer Center have completed a phase II clinical trial to determine the safety and efficacy of dasatinib (Sprycel) for patients with higher-risk myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, or acute myeloid leukemia resulting from MDS and have failed ...

For Smokers, Low Levels of Vitamin D May Lead to Cancer

New research published online in Clinical Chemistry, the journal of the American Association for Clinical Chemistry, shows that decreased levels of vitamin D may predispose smokers to developing tobacco-related cancer. This study illustrates that simple vitamin D blood tests and supplements have...

breast cancer

Radiation Raises Risk of Heart Disease in Women Treated for Breast Cancer

A population-based case control study of major coronary events in 2,168 women who underwent radiotherapy for breast cancer between 1958 and 2001 in Sweden and Denmark found a direct link between radiation dose and the occurrence of ischemic heart disease years later. Study Details The study,...

survivorship

NCCN Issues New Guidelines for Survivorship

The National Comprehensive Cancer Network (NCCN) has issued its first ever NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Survivorship. The new NCCN Guidelines were presented at the NCCN 18th Annual Conference: Advancing the Standard of Cancer Care by Panel Chair, Crystal S....

breast cancer

High-fat Dairy Products Linked to Poorer Breast Cancer Survival

Patients who consume high-fat dairy products following breast cancer diagnosis increase their chances of dying from the disease years later, according to a study by Kaiser Permanente researchers. The study, published in the Journal of the National Cancer Institute, is the first to examine the...

health-care policy

Survey of Oncology Providers Shows Sequestration Cuts Will Threaten Seniors' Cancer Care and Increase Medicare Costs

The Community Oncology Alliance (COA) has announced the results of a national survey of oncology providers about the impact of the sequestration cuts to Medicare payments for cancer drugs and services effective April 1, 2013.  The survey revealed that the planned sequestration cuts to cancer...

gynecologic cancers

More Than 60% of Ovarian Cancer Patients Do Not Receive Recommended Treatment, Study Shows

Women are 30% less likely to die of ovarian cancer if they have guideline-recommended treatment, yet nearly two-thirds of those with the disease do not receive it, often because they are cared for at hospitals that treat a small number of ovarian cancer patients. These are the findings of a study...

lymphoma

High-dose Vorinostat Effective at Treating Relapsed Lymphomas, Study Finds

Reporting the results of a phase I clinical trial to test the effectiveness of a new class of drugs to augment standard chemotherapy, a team led by Fred Hutchinson Cancer Research Center scientists found that giving patients high doses of vorinostat (Zolinza) in combination with another round...

Alex’s Lemonade Stand Foundation Introduces Centers of Excellence Program to Further Childhood Cancer Research

Alex’s Lemonade Stand Foundation (ALSF), a registered 501(c)(3) charity, is furthering its commitment to finding cures for all children with cancer by introducing the ALSF Centers of Excellence program. The Centers of Excellence program aims to fund the research of leading childhood cancer...

Report to the Nation Shows U.S. Cancer Death Rates Continue to Drop

The Annual Report to the Nation on the Status of Cancer, 1975–2009, shows that overall cancer death rates continued to decline in the United States among both men and women, among all major racial and ethnic groups, and for all of the most common cancer sites, including lung, colon and...

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