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Oncology Meetings

FEBRUARY 25th International Congress on Anti-Cancer TreatmentFebruary 4-6 • Paris, FranceFor more information: www.icact.fr APOS 11th Annual ConferenceFebruary 13-15 • Tampa, FloridaFor more information:www.apos-society.org/apos2014/ European Society for Medical Oncology Sarcoma and GIST...

Champions Oncology Names Chief Medical Officer

Champions Oncology, a company engaged in the development of advanced technology solutions and services to personalize the development and use of oncology drugs, has announced the appointment of Angela Davies, MD, as Chief Medical Officer. Dr. Davies has demonstrated experience in both academic...

Texas Children’s Hospital Announces New Chief of Interventional Radiology

The Department of Pediatric Radiology at Texas Children’s Hospital recently announced that Kamlesh U. Kukreja, MD, has been named the new Chief of Interventional Radiology. Dr. Kukreja has also been appointed as Assistant Professor of Radiology at Baylor College of Medicine. “For more than a...

Expect Questions, and Some Reluctance, About Getting a Flu Shot

People with weakened immune systems due to diseases like cancer are at increased risk of severe complications from the flu virus and should get flu shots annually. The Centers for Disease Control and Prevention (CDC) strongly encourages this practice, and most oncologists would recommend that for...

supportive care

Cancer Patients Are at Increased Risk of Complications From the Flu and Should Receive Flu Shots, but Not the Nasal Spray

Widespread influenza activity continues to be reported by the Centers for Disease Control and Prevention (CDC), with a recent increase in flu-related hospitalizations.1,2 Patients with cancer are at increased risk from flu complications and should receive the flu shot, but not the flu nasal spray...

Grant to Develop Website and Mobile App to Track Radiation Therapy Toxicity Awarded to Radiation Oncology Resident

The Radiation Oncology Institute has selected Malolan S. Rajagopalan, MD, a radiation oncology resident at the University of Pittsburgh Cancer Institute, to receive a $20,000 grant for a project to compile best practices regarding the management of radiation therapy toxicity. Dr. Rajagopalan’s...

cns cancers

An Overview of the REGAL Trial and Anti-VEGF Therapies in Recurrent Glioblastoma

As published in the Journal of Clinical Oncology by Batchelor and colleagues1 and reviewed in a recent issue of The ASCO Post (November 15, 2013, page 106), the REGAL trial was a randomized, phase III, placebo-controlled, partially blinded trial evaluating the efficacy of cediranib, an...

Major Cancer Milestones in History, From ASCO’s CancerProgress.Net

To help tell the story of progress against cancer, ASCO launched CancerProgress.Net in 2011. The site is intended as a resource for media, policymakers, oncologists, advocates, and the public. One central feature of the site is an interactive timeline of major milestones in cancer treatment,...

Gary Lyman, MD, Joins Scott Ramsey, MD, PhD, in Co-Leading Hutchinson Institute for Cancer Outcomes Research at Fred Hutchinson

The Hutchinson Institute for Cancer Outcomes Research (HICOR) has named Gary Lyman, MD, MPH, the Institute’s Co-Director with Scott Ramsey, MD, PhD, an internist and health-care economist, and a member of the Cancer Prevention Program in the Public Health Sciences Division at Fred Hutchinson Cancer ...

global cancer care

Reports From the IPOS/AORTIC Travel Scholars

Eight individuals were awarded travel scholarships allowing them to attend the IPOS/AORTIC Program (International Psycho-Oncology Society/African Organization for Research and Training in Cancer) and share their experiences and efforts toward improving the psychosocial care of patients with cancer...

issues in oncology
health-care policy

Surgeon General’s New Report Attributes Smoking as Cause of Death in More Than 20 Million Americans Over Past 50 Years

According to a new Surgeon General’s report issued last month, more than 20 million Americans have died from smoking over the past 50 years. The new report concludes that cigarette smoking kills nearly half a million Americans a year, with an additional 16 million suffering from smoking-related...

issues in oncology
health-care policy

50th Anniversary of the First U.S. Surgeon General’s Report on Smoking and Health

“When the first Surgeon General’s Report was released in 1964, more than half of American men and over a third of women smoked and lung cancer had gone from an obscure disease to a leading cause of death. In issuing this pioneering report summarizing the known health risks of smoking, our nation’s...

issues in oncology

Health IT Safety Guide

A new set of guides and interactive tools to help health-care providers more safely use electronic health information technology products, such as electronic health records (EHRs), are now available at www.HealthIT.gov. The Office of the National Coordinator for Health Information Technology (ONC)...

skin cancer

FDA Approves Combination Therapy for Unresectable or Metastatic Melanoma With BRAF V600E/K Mutations

The U.S. Food and Drug Administration (FDA) has approved trametinib (Mekinist) for use in combination with dabrafenib (Tafinlar) for the treatment of patients with unresectable melanoma or metastatic melanoma with BRAF V600E or V600K mutations. These mutations must be detected by an FDA-approved...

lung cancer

Dabrafenib Receives FDA Breakthrough Therapy Designation for BRAF-Mutated NSCLC

The U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation for dabrafenib (Tafinlar) for the treatment of patients with metastatic BRAF V600E mutation–positive non–small cell lung cancer (NSCLC) who have received at least one prior line of platinum-containing...

palliative care

ASCO Cosponsors Inaugural Palliative Care in Oncology Symposium

In October, ASCO will cosponsor the inaugural Palliative Care in Oncology Symposium with the American Academy of Hospice and Palliative Medicine (AAHPM), the American Society for Radiation Oncology (ASTRO), and the Multinational Association of Supportive Care in Cancer (MASCC). The Symposium is...

global cancer care

ASCO Member Helps to Strengthen Cancer Care Internationally Through Philanthropy and Volunteer Service

Ian F. Tannock, MD, PhD, DSc, FASCO, Professor of Medical Oncology at Princess Margaret Hospital and University of Toronto, has long been an advocate for ASCO as a truly global society and a leader in cancer care worldwide. It’s something he encouraged during his time on ASCO’s Board of Directors,...

global cancer care

IPOS/AORTIC Conference Aims to Bring Comprehensive Care to Patients in Africa

More than 1,000 scientists from 66 countries, including 32 of the 52 African countries, attended the African Organization for Research and Training in Cancer (AORTIC) 9th International Conference on Cancer in Africa, held this past November in Durban, South Africa. The theme of the 2013 meeting was ...

Expert Point of View: Matthew Ellis, MB, PhD

Matthew Ellis, MB, PhD, Professor of Medicine and the Anheuser-Busch Chair in Medical Oncology at Washington University School of Medicine, St. Louis, commented for The ASCO Post on the emerging field of research on drugging PI3K mutations. Critical Mechanisms “Multiple somatic lesions in breast...

lung cancer

Lung Cancer Screening Facts

The U.S. Preventive Services Task Force has posted a supplemental fact sheet for clinicians on its final recommendation statement on screening for lung cancer.1 This resource is meant to help health-care professionals talk about lung cancer screening with their patients and determine if screening...

Expert Point of View: Andrew D. Zelenetz, MD, PhD

Andrew D. Zelenetz, MD, PhD, Chair of the Non-Hodgkin Lymphoma Guideline Panel of the National Comprehensive Cancer Network (NCCN) and former Chief of the Lymphoma Service at Memorial Sloan-Kettering Cancer Center, New York, commented on the study by Yamshon et al for The ASCO Post. He said the...

breast cancer

Addition of Carboplatin to Standard Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Supported by SABCS Studies

The achievement of a pathologic complete response in patients with triple-negative breast cancer was boosted by the addition of carboplatin to a standard neoadjuvant chemotherapy regimen, and by the addition of veliparib, an investigational oral PARP inhibitor, plus carboplatin to a standard...

Corrections to Note

In the January 15, 2014, issue of The ASCO Post, three errors occurred. These errors have since been corrected and revised versions of the articles may be viewed online at ASCOPost.com or via the QR code here. The errors were as follows below. Trastuzumab Dosing In the article “HER2-Positive...

Expect Questions from Patients

Like all early detection strategies, screening mammography involves trade-offs,” H. Gilbert Welch, MD, MPH, and Honor J. Passow, PhD, of the Dartmouth Institute for Health Policy & Clinical Practice, Hanover, New Hampshire, wrote in a Special Communication in JAMA Internal Medicine.1 They...

breast cancer
issues in oncology

Confronting Uncertainty About the Harms and Benefits of Screening Mammography

“If women are to truly participate in the decision of whether or not to be screened [for breast cancer using mammography], they need some quantification of its benefits and harms,” asserted H. Gilbert Welch, MD, MPH, Professor of Medicine, and Honor J. Passow, PhD, Instructor, at The Dartmouth...

global cancer care

UN Agency Issues World Cancer Report 2014

A new global cancer report1 compiled by the United Nations’ International Agency for Research on Cancer (IARC) shows, as a single entity cancer is the biggest cause of mortality worldwide, and there were an estimated 8.2 million deaths from cancer in 2012. The report also noted that global cancer...

2014 Oncology Meetings

FEBRUARY European Society for Medical Oncology Sarcoma and GIST 2014February 18-19 • Milan, ItalyFor more information: www.esmo.org 2014 BMT Tandem MeetingAmerican Society for Blood and Marrow TransplantationFebruary 19 - 23 • Orlando, FloridaFor more information: www.asbmt.org Multidisciplinary...

NIH Names First Chief Officer for Scientific Workforce Diversity, Hannah Valantine, MD

National Institutes of Health (NIH) Director Francis S. ­Collins, MD, PhD, has appointed Hannah Valantine, MD, to Chief Officer for Scientific Workforce Diversity. Dr. Valantine will lead NIH’s effort to diversify the biomedical research workforce by developing a vision and comprehensive strategy...

Richard J. Gannotta, DHA, FACHE, Named President Northwestern Memorial Hospital

Northwestern Memorial HealthCare (NMHC) has announced that it has named Richard J. Gannotta, DHA, FACHE, President, Northwestern Memorial Hospital and Senior Vice President, NMHC effective this month. Dr. Gannotta was President of Duke Raleigh Hospital of the Duke University Health System. “Rick is ...

gynecologic cancers

An Early Chemotherapy Innovator, Franco M. Muggia, MD, Now Focuses on Advancing Therapies for Ovarian Cancer

Looking over an illustrious career in medical oncology that spans 5 decades, Franco M. Muggia, MD, told The ASCO Post that he is excited about the future and hopes to continue making contributions to the field of oncology in years to come. At the forefront of the early clinical development of...

hematologic malignancies
issues in oncology

Focus on the Michigan Society of Hematology and Oncology

Founded nearly 3 decades ago in response to unfavorable changes in Medicare reimbursement regulations and growing coverage issues with Michigan’s private payers that threatened oncologists’ ability to provide quality cancer care to patients, the Michigan Society of Hematology and Oncology (MSHO)...

Milestones in Oncology, From ASCO’s CancerProgress.Net

To help tell the story of progress against cancer, ASCO launched CancerProgress.Net in 2011. The site is intended as a resource for media, policymakers, oncologists, advocates, and the public. One central feature of the site is an interactive timeline of major milestones in cancer treatment,...

Radiation Oncology Institute Awards $200,000 Grant to Christopher Slatore, MD

The Radiation Oncology Institute (ROI) has named Christopher G. Slatore, MD, recipient of a $200,000 award, distributed over 2 years, for a project to examine the comparative value of radiation therapy and patient outcomes among patients with lung cancer. Dr. Slatore is Assistant Professor in the...

lymphoma

City of Hope Receives $10 Million Gift to Launch Lymphoma Research and Treatment Center

A $10 million gift from Internet publishing entrepreneurs and philanthropists Emmet and Toni Stephenson and their daughter Tessa Stephenson Brand will fund the creation of the Toni Stephenson Lymphoma Center at City of Hope, Duarte, California, the cornerstone of the institution’s new Hematologic...

palliative care

NIH Makes Palliative Care More Attainable for Pediatric Patients and Their Families

A campaign “Palliative Care: Conversations Matter” recently launched by the National Institute of Nursing Research (NINR) aims to increase the use of palliative care for children with serious illness. Palliative care can reduce a child’s pain, help manage other distressing symptoms, and provide...

Indiana University Simon Cancer Center Receives $15 Million Pledge

The Vera Bradley Foundation for Breast Cancer recently announced a $15 million pledge to support breast cancer research at the Indiana University Melvin and Bren Simon Cancer Center. This new pledge adds to the previous $20 million in commitments completed in November 2013 and will continue to fund ...

prostate cancer

Impact of Comprehensive Lifestyle Change on Telomere Length and Telomerase Activity in Men With Low-Risk Prostate Cancer

Ornish et al at the University of California in San Francisco and the Preventive Medicine Research Institute in Sausalito, California, performed a 5-year study1 including 35 men on active surveillance (10 in a lifestyle-intervention group and 25 in a control group) with low-risk prostate cancer....

pancreatic cancer

University of Pittsburgh Researchers Awarded More than $1 Million by NIH to Study New Treatments for Pancreatic Cancer Patients

The National Institutes of Health (NIH) has awarded a 5-year grant of more than $1.5 million to Herbert J. Zeh III, MD, and Michael T. Lotze, MD, at the University of Pittsburgh Cancer Institute (UPCI), partner with UPMC CancerCenter, to study a novel treatment for pancreatic ductal ...

breast cancer

HER2 Testing: The Next Chapter

Late last year, the American Society of Clinical Oncology and College of American Pathologists published a comprehensive update of guidelines for HER2 testing,1 the first such update since their initial landmark publication in 2007.2 This new report, summarized in this issue of The ASCO Post,...

lymphoma

Longer-Term Follow-up of Breast Implant–Associated Anaplastic Large Cell Lymphoma: More Certainty About Certain Uncertainties

When what is now called breast implant–associated anaplastic large cell lymphoma was first recognized and initially described, a number of uncertainties prevailed—mainly, was the association with breast implants real, and was this a true lymphoma? Through the significant efforts of those who...

Expert Point of View: Andrew D. Zelenetz, MD, PhD

Andrew D. Zelenetz, MD, PhD, Chair of the Non-Hodgkin Lymphoma Guideline Panel of the National Comprehensive Cancer Network (NCCN) and former Chief of the Lymphoma Service at Memorial Sloan-Kettering Cancer Center, New York, put the latest maintenance trials into perspective for The ASCO Post....

breast cancer
pain management

Postmastectomy Pain Effectively Treated With a Simple Injection

For postmastectomy neuropathic pain, perineural infiltration with a combination of bupivacaine and dexamethasone is a “simple, effective, practice-changing treatment that any surgeon can do,” according to Laura J. Esserman, MD, MBA, Professor of Surgery and Radiology at the University of...

breast cancer

SABCS Highlights Include Findings in Triple-Negative Disease, Protective Effects of Exercise, and the Adherence-Copay Link

The San Antonio Breast Cancer Symposium brings together specialists from all over the world who focus on management of breast cancer. We have covered many of the important presentations in the pages of The ASCO Post and in our online Evening News. Below are summaries of additional noteworthy...

issues in oncology

New Society Launched for Advanced Practitioners in Hematology and Oncology

The Advanced Practitioner Society for Hematology and Oncology (APSHO) announced its launch as a new organization focused on meeting the unique educational and professional needs of the advanced practitioner in hematology and oncology. The formation of the Society was made public on January 26,...

Margaret A. Tempero, MD, Named Editor-in-Chief of JNCCN

JNCCN – Journal of the National Comprehensive Cancer Network, the journal of the National Comprehensive Cancer Network (NCCN), has named Margaret A. Tempero, MD, as Editor-in-Chief. Dr. Tempero assumed the position of Editor-in-Chief on February 3, 2014, succeeding Harold J. Burstein, MD, PhD, who...

leukemia

FDA Approves CliniMACS CD34 Reagent System for the Prevention of Graft-vs-Host Disease in AML

The U.S. Food and Drug Administration (FDA) has approved the Miltenyi Biotec’s CliniMACS CD34 Reagent System as a Humanitarian Use Device for the prevention of graft-vs-host disease in patients with acute myeloid leukemia (AML) in first complete remission undergoing allogeneic stem cell...

lymphoma

FDA Accepts New Drug Application for Idelalisib in Refractory Indolent Non-Hodgkin Lymphoma

The U.S. Food and Drug Administration (FDA) has accepted the New Drug Application (NDA) for idelalisib, a targeted, oral inhibitor of PI3K-delta, for the treatment of refractory indolent non-Hodgkin lymphoma (NHL). The FDA has granted a standard review for the NDA, with a target review date of...

Jamie H. Von Roenn, MD, and ASCO: A Perfect Fit

Dr. Von Roenn’s history with ASCO spans nearly 3 decades. She has served on ASCO’s Board of Directors, the ASCO Palliative Care Task Force, the Scientific Program, Cancer Education, and Cancer Communications Committees, among others. In 2011, Dr. Von Roenn received the ASCO-ACS Award at the Annual...

ASCO's Education and Professional Development Services

Last September, Jamie H. Von Roenn, MD, left her position as Professor of Medicine at the Northwestern University Feinberg School of Medicine in Chicago to join ASCO as its Senior Director of Education, Science and Professional Development. In her new position, Dr. Von Roenn will provide strategic...

Perspective on the Politics of Tobacco

The tobacco industry has always been a major player in congressional races, especially in Southern tobacco-growing states. Moreover, the industry is notoriously bipartisan in their political donations, and members of both parties have returned the favor by voting for tobacco interests. “The 2014...

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