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survivorship

ASCO Issues Clinical Expert Statement on Cancer Survivorship Care Planning

Efforts at implementing survivorship care plans have met with limited success in oncology practice, in part due to the time required to complete survivorship care plans, lack of role clarity, and lack of reimbursement for time to complete the documents. In response, ASCO convened a Survivorship...

breast cancer
survivorship

Dutch Study Finds No Increased Risk of Cardiovascular Mortality in 5-Year Survivors of DCIS

In a Dutch study reported in the Journal of the National Cancer Institute, Boekel et al found no increase in risk of cardiovascular mortality among 5-year survivors of ductal carcinoma in situ (DCIS) compared with the general population. Among DCIS patients, risk of cardiovascular events did not...

survivorship

Chemoradiotherapy vs Radiotherapy Alone Linked to Increased Risk of Subsequent Malignancies in Long-Term Survivors of Hereditary Retinoblastoma

Increased risk of subsequent malignant neoplasms has been reported in hereditary retinoblastoma survivors after radiotherapy. In a study reported in Journal of Clinical Oncology, Wong et al found that chemotherapy plus radiotherapy was associated with increased risk of subsequent malignant...

lymphoma
survivorship

Study Estimates Risk of Premature Menopause After Treatment for Hodgkin Lymphoma

Previous research has suggested that women with Hodgkin lymphoma who receive certain types of chemotherapy or radiotherapy are at increased risk of future infertility, but there was insufficient information to provide patients with detailed advice. In a study published in the Journal of the...

survivorship

Poorer Psychosexual Functioning in Adult Female Survivors of Childhood Cancer

In an analysis in the Childhood Cancer Survivor Study population reported in the Journal of Clinical Oncology, Ford et al found that adult woman survivors of childhood cancer have poorer psychosexual function than their siblings without childhood cancer. Risk factors for poorer function included...

survivorship

Failure to Adopt a Healthy Lifestyle More Than Doubles Risk of Metabolic Syndrome in Childhood Cancer Survivors

A St. Jude Children’s Research Hospital study found that 73% of adult survivors of childhood cancer more than doubled their risk of developing metabolic syndrome and related health problems by failing to follow a heart-healthy lifestyle. The results were published online in the journal...

supportive care
survivorship

No Clinical Outcome Benefit With Aerobic Training Program in Cancer Patients With Heart Failure

In a retrospective analysis in the HF-ACTION trial reported in the Journal of Clinical Oncology, Jones et al found that a program of aerobic training did not reduce the rate of all-cause mortality or hospitalization in cancer patients with heart failure. Some evidence suggested that patients who...

leukemia
survivorship

Excess Risk of Chronic Late Effects of Treatment in Children With Standard-Risk ALL

Given the changes in treatment of children with acute lymphoblastic leukemia (ALL), the risk of late effects in those treated with current protocols may be different from that in children treated decades ago. In a study of survivors of childhood standard-risk ALL reported in The Lancet Oncology,...

survivorship

Danish Study Shows Increased Risk of Cardiovascular Disease Throughout Life in Survivors of Adolescent and Young Adult Cancer

In a Danish cohort study reported in the Journal of the National Cancer Institute, Rugbjerg and colleagues found that survivors of adolescent and young adult cancer are at increased risk of cardiovascular disease throughout life, with cardiovascular disease profiles differing according to cancer...

survivorship

Survivors of Childhood Cancers Experience Frequent Hospitalizations Years After Cancer Treatment

Childhood and adolescent cancer survivors often face ongoing health problems that require frequent and long hospital stays many years after their cancer diagnosis and treatment, according to a new study by Kirchhoff et al published in Cancer Epidemiology, Biomarkers & Prevention. Survivors of...

breast cancer
survivorship

ASCO 2014: Goserelin Helps Preserve Fertility Among Women Receiving Chemotherapy for Hormone Receptor–Negative Breast Cancer

Adding goserelin (Zoladex) to standard chemotherapy may be an effective method of preserving fertility among women with early-stage hormone receptor–negative breast cancer, according to findings from a federally funded phase III clinical trial. In the S0230/POEMS study, reported at the 2014...

survivorship

Study Suggests Less Frequent Cardiac Screening May Be Preferable for Survivors of Childhood Cancer

One of the first studies to analyze the effectiveness of screening survivors of childhood cancer for early signs of impending congestive heart failure found improved health outcomes but suggested that less frequent screening than currently recommended may yield similar clinical benefit. Researchers ...

survivorship

Minority of Oncologists and Primary Care Physicians Fully Discuss Survivorship Care Plans With Cancer Survivors

Of 53 National Cancer Institute cancer centers, only 43% report implementing survivorship care plans for at least some of their cancer survivors. In a study reported in the Journal of Clinical Oncology, Blanch-Hartigan et al found that a minority of a nationally representative sample of oncologists ...

breast cancer
survivorship

Cumulative Risk of Breast Cancer Reaches 30% by Age 50 After Chest Irradiation for Childhood Cancer

The incidence of breast cancer in women treated with chest radiation therapy for childhood cancer previously has been estimated at 5% to 14% by age 40 years and is among the highest reported for any population. In a study reported in the Journal of Clinical Oncology, Moskowitz et al found that the...

breast cancer
survivorship

Receiving Chemotherapy After a Breast Cancer Diagnosis May Affect a Patient’s Long-Term Employment

A new study has found that loss of paid employment after a diagnosis of early-stage breast cancer may be common and potentially related to the type of treatment patients received. Published early online in Cancer, the findings by Jagsi et al support efforts to reduce the side effects and burden of...

survivorship

Health Gap Between Adult Survivors of Childhood Cancer and Siblings Widens With Age

Adult survivors of childhood cancer face significant health problems as they age and are five times more likely than their siblings to develop new cancers, heart disease, and other serious health conditions beyond the age of 35, according to the latest findings from the Childhood Cancer Survivor...

supportive care
survivorship

NCCN Cancer Survivorship Guidelines Expanded to Address Two Common Conditions

The National Comprehensive Cancer Network (NCCN) has expanded its Survivorship Guidelines to include a section on cancer-associated cognitive impairment, and to include chemotherapy-induced peripheral neuropathy as a component of the Adult Cancer Pain section. The inaugural guidelines for...

breast cancer
supportive care
survivorship

Epigenetic Imprint of Chemotherapy Linked to Inflammation in Breast Cancer Survivors

Many breast cancer survivors experience fatigue and other debilitating symptoms that persist months to years after their course of treatment has ended. Now researchers at the Winship Cancer Institute of Emory University have found clues that may explain how these symptoms can linger. Chemotherapy...

survivorship

Childhood Cancer Survivors at Very High Risk of Later Endocrine Disorders in Scandinavian Study

In a population-based cohort study (Adult Life after Childhood Cancer in Scandinavia, or ALiCCS) reported in The Lancet, Licht et al assessed the lifetime risk of endocrine disorders in Scandinavian long-term survivors of childhood cancer. They found a nearly fivefold increased risk of hospital...

breast cancer
supportive care
survivorship
integrative oncology

Yoga Improves Inflammation, Fatigue, and Vitality in Breast Cancer Survivors

In a study reported in the Journal of Clinical Oncology, Kiecolt-Glaser et al found that yoga reduced levels of inflammatory cytokines and fatigue and increased vitality in breast cancer survivors. Study Details In the study, 200 women with stage 0 to IIIA breast cancer who had completed...

survivorship

Is the Traumatic Impact of Cancer Overestimated in Children With Cancer?

In a study reported in the Journal of Clinical Oncology, Phipps et al found no evidence of increased post-traumatic stress disorder (PTSD) or post-traumatic stress symptoms (PTSS) in children with cancer and observed a heightened sense of perceived growth related to cancer events in these children. ...

survivorship

Survey Finds Many General Internists Are Uncomfortable Caring for Adult Survivors of Childhood Cancer

A National Cancer Institute–funded survey of general internists asking about their attitudes and knowledge about the care of adult childhood cancer survivors has found that few internists are comfortable caring for these patients. Moreover, many are unfamiliar with the Children’s...

prostate cancer
survivorship

Long-Term Symptoms Beyond 10 Years Experienced by Prostate Cancer Survivors

Years after receiving treatment, many patients who survive prostate cancer continue to experience treatment-related symptoms, according to the findings of a study by Darwish-Yassine et al published in the Journal of Cancer Survivorship. These findings highlight the need for improvements in survivor ...

supportive care
survivorship

Internet-Based Intervention Improves Cancer-Related Sexual Dysfunction in Women

An Internet-based intervention may significantly improve both sexual function and satisfaction in women with sexual dysfunction years after treatment for breast or gynecologic cancer, according to a randomized trial reported in the November issue of the Journal of the National Comprehensive Cancer...

leukemia
survivorship

Persistent Significant Neurocognitive Impairment in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

In a study reported in the Journal of Clinical Oncology, Kevin R. Krill, PhD, and colleagues from St. Jude Children’s Research Hospital assessed neurocognitive function in adult survivors of childhood acute lymphoblastic leukemia (ALL). They found pervasive significant impairment across...

survivorship

Association Between Prevalence of Symptoms and Impaired Health-Related Quality of Life in Adult Survivors of Childhood Cancer

In a study reported in the Journal of Clinical Oncology, I-Chan Huang, PhD, of University of Florida at Gainesville, and colleagues investigated the association between prevalence of symptoms and health-related quality of life in adult survivors of childhood cancer enrolled in the St. Jude...

survivorship

Improvements Needed in Use of Survivorship Care Plans

Survivorship care plans, consisting of treatment summaries and follow-up plans, are intended to promote coordination of post-treatment cancer care, but little is known about how they are being used in routine oncology practice. In a study reported in the Journal of the National Cancer...

skin cancer
issues in oncology
survivorship

Intervention Program Improves Sun Protection Practices Among Children of Melanoma Survivors

Children of melanoma survivors were more likely to wear hats and reapply sunscreen after receiving a multimedia informational program designed specifically for them. These new findings were included in research published in Cancer Epidemiology, Biomarkers & Prevention. A team of researchers...

health-care policy
survivorship

Older Cancer Survivors in Rural Areas Forgo Health Care Due to Cost

Rural cancer survivors aged 65 or older were 66% more likely to forgo routine follow-up health care and 54% more likely to forgo dental care because of cost, compared with their urban counterparts, according to a study by Nynikka Palmer, DrPH, MPH, Post-doctoral Fellow in the Department of Social...

survivorship

Long-Term Survivors of Childhood Cancer Exhibit Vascular Endothelial Damage

In a study reported in Journal of Clinical Oncology, Cornelia A.J. Brouwer, of the University Medical Center Groningen in the Netherlands, and colleagues assessed vascular parameters in long-term childhood cancer survivors and sibling controls. They found that survivors who had received...

prostate cancer
survivorship

Men With Advanced Prostate Cancer Worry More About Burdening Family and Friends Than Dying, Survey Finds

Men with advanced prostate cancer are now living longer than ever, and it is estimated that one in six U.S. men will be diagnosed with prostate cancer in their lifetime. However, little research has been conducted to understand the psychosocial needs of these men and their caregivers after...

survivorship

Childhood Cancer Survivors Who Received Nephrotoxic Therapy May Be at Greater Risk for Late Renal Problems

A large study assessing glomerular function in adult survivors of childhood cancers who were treated with certain chemotherapy drugs or kidney surgery found that they had worse kidney function, which did not recover over time, compared with adult survivors who were not given nephrotoxic therapy....

survivorship

Modifiable Risk Factors Potentiate Therapy-Associated Risk for Major Cardiac Events in Adult Survivors of Childhood Cancer

In a study reported in Journal of Clinical Oncology, Gregory T. Armstrong, MD, of St. Jude Children’s Research Hospital in Memphis, and colleagues assessed the frequency of major cardiac events and cardiovascular risk factors among adult survivors of childhood cancer and their siblings. They...

breast cancer
survivorship

Large Study Shows That Radiation Therapy for DCIS May Not Increase Cardiovascular Disease Risk

A large population-based study in the Netherlands found that women who had received radiation therapy to treat ductal carcinoma in situ of the breast (DCIS) have no increased risk of cardiovascular disease compared to the general population of Dutch women, nor compared to DCIS patients treated with ...

breast cancer
survivorship

Quality of Life Improves Over Time and Is Similar in Long-Term Breast Cancer Survivors and Women With No History of Breast Cancer

In a study reported in Journal of Clinical Oncology, Pamela J. Goodwin, MD, and Tina Hsu of University of Toronto and colleagues assessed changes in quality of life from time of breast cancer diagnosis to long-term survivorship and compared quality of life in long-term survivors to that of...

survivorship

Danish Study Evaluates Risk of Mental Disorders in Siblings of Childhood Cancer Survivors

Survivors of childhood cancer are at risk for long-term adverse physical and mental effects, but little is known about the effects of illness in siblings of these patients. In a study reported in Lancet Oncology, Lasse Wegener Lund, MD, of the Danish Cancer Society Research Centre in...

lymphoma
survivorship

NCI Study Links Hodgkin Lymphoma Treatment to Risk of Stomach Cancer

Hodgkin lymphoma survivors who received subdiaphragmatic radiotherapy and chemotherapy regimens containing high doses of the alkylating agent procarbazine (Matulane) were at an increased risk of developing stomach cancer, according to a large study by scientists at the National Cancer Institute...

lymphoma
survivorship

Decreased White Matter Integrity and Neuropsychological Function Seen Decades After Cranial Radiotherapy for Pediatric Lymphoid Malignancies

CNS-directed chemotherapy and cranial radiation therapy for childhood acute lymphoblastic leukemia or lymphoma have neurotoxic effects. In a study reported in Journal of Clinical Oncology, Ilse Schuitema, MSc, of Leiden University, The Netherlands, and colleagues evaluated white matter changes ...

survivorship

Female Survivors of Childhood Cancer Have Increased Risk of Infertility

Decreased pregnancy rates and early menopause have been reported in female cancer survivors, although there is less information on infertility rates and reproductive interventions in these patients. In a study reported in Lancet Oncology, Sara E. Barton, MD, of Brigham and Women’s Hospital...

breast cancer
survivorship

Cancer Survivors Have More Frequent and Severe Menopausal Hot Flashes

Women who survive cancer have more frequent, severe, and troubling hot flashes than other women with menopausal symptoms, according to a study published online in Menopause, the journal of The North American Menopause Society (NAMS). But surprisingly, the cancer survivors fare better...

survivorship

Cancer Survivors Might Have a Decreased Risk for Alzheimer's Disease

The results from a large cohort study of 3.5 million veterans in the Veterans Affairs (VA) Boston Healthcare System show that most types of cancer were associated with a reduced risk of developing Alzheimer’s disease of between 9% and 51%. The cancers associated with the greatest reduction in ...

issues in oncology
survivorship

Cancer Patients with Cardiovascular Risk Factors Who Receive Chest Radiation Should Have Cardiovascular Screening Every 5 to 10 Years

Cancer patients who receive chest radiation should be screened for heart disease every 5 to 10 years, according to the European Association of Cardiovascular Imaging (EACVI) of the European Society of Cardiology and the American Society of Echocardiography. Their recommendations are outlined in the ...

colorectal cancer
survivorship

Colorectal Cancer Survivors Face Increased Risk of Developing Subsequent Cancers of Different Types

According to a new study, colorectal cancer survivors face an increased risk of developing subsequent primary cancers, particularly second colorectal cancers and small intestinal cancers. These findings, published online in Cancer, may help in the development of screening guidelines for patients...

survivorship

Anxiety Is a Long-term Problem for Cancer Survivors and Spouses

An analysis assessing whether depression and anxiety are more common in long-term survivors of cancer compared with their spouses and with healthy control subjects has found that anxiety, rather than depression, is most likely to be a lingering problem for both cancer survivors and their spouses....

colorectal cancer
survivorship

Chemotherapy-induced Neuropathy Has Long-term Effect on Colorectal Cancer Survivors

In a study reported in Journal of Clinical Oncology, Floortje Mols, PhD, of the Center of Research on Psychology in Somatic Diseases, Tilburg University, and colleagues assessed the prevalence and severity of chemotherapy-induced neuropathy and its affect on health-related quality of life in...

breast cancer
survivorship

Few Breast Cancer Survivors Maintain Adequate Physical Activity Despite Benefits

Breast cancer survivors are among the women who could most benefit from regular physical activity, yet few meet national exercise recommendations during the 10 years after being diagnosed, according to a study by researchers at Fred Hutchinson Cancer Research Center. Prior studies and available...

survivorship

Number of Cancer Survivors Expected to Increase to 18 Million by 2022

The American Association for Cancer Research released its second Annual Report on Cancer Survivorship in the United States in advance of the AACR Annual Meeting 2013, which will be held in Washington, DC, April 6-10. The report, published in the AACR’s journal Cancer Epidemiology, Biomarkers ...

survivorship

Cancer in Young Adults Is Focus of New Nationwide Study to Be Led by Fred Hutchinson Cancer Research Center Survivorship Program

The Fred Hutchinson Cancer Research Center Survivorship Program and its directors, K. Scott Baker, MD, and Karen Syrjala, PhD, have been selected to lead a nationwide study that aims to improve long-term health outcomes for cancer survivors between the ages of 18 and 39. Underway this spring, the...

survivorship

NCCN Issues New Guidelines for Survivorship

The National Comprehensive Cancer Network (NCCN) has issued its first ever NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Survivorship. The new NCCN Guidelines were presented at the NCCN 18th Annual Conference: Advancing the Standard of Cancer Care by Panel Chair, Crystal S....

supportive care
survivorship

Study Shows Confidence Builds Better Exercise Habits for Cancer Survivors

Endometrial cancer survivors are more likely to complete physical activity, and for longer durations, when their daily self-efficacy is higher, according to a study published online in the journal Health Psychology, a publication of the American Psychology Association. “Sedentary behavior is ...

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