Clifford A. Hudis, MD, FASCO, FACP, on ASCO Guidelines Assistant
2025 ASCO Annual Meeting
Clifford A. Hudis, MD, FASCO, FACP, Chief Executive Officer of ASCO, discusses ASCO Guidelines Assistant, an AI-based collaboration between ASCO and Google Cloud which draws from ASCO’s evidence-based, published clinical practice guidelines, offering clinicians ready access to timely, trustworthy information.
Transcript
Disclaimer: This video transcript has not been proofread or edited and may contain errors.
I want to welcome everybody to the 2025 ASCO Annual Meeting. This is, as always, an exciting time in the year for us, when so much new science gets presented. Today, what I’m really excited about—above and beyond the cutting-edge new knowledge that’s being shared at this meeting—is how we’re going to distribute it to maximize impact for patients everywhere. The growth in information is something that we’re all grappling with. The explosion in publications—papers, that is—and information that could truly benefit patients is, I think, well known. The question is: how do we keep up? Even within ASCO, where we generate trusted, vetted, expert-prepared, peer-reviewed guidelines, it can be a problem just to find the information that a busy clinician needs in their day to make sure they are offering their patients the most up-to-date care possible. So thinking about those two related issues—the exploding basis of knowledge and the challenge of navigating to quick, accurate answers that a clinician can trust—the last year for us at ASCO has been an exciting one. We’ve partnered and collaborated with Google Cloud to create the ASCO Guidelines Assistant. And it is exactly what the name says—it’s really a discovery tool. What’s different about it compared to some other chat experiences that members may have had is that its answers to our questions are limited to the content of our guidelines. For every answer it gives, it automatically provides the relevant citation. If a user clicks on it, it shows them the specific guideline, when it was last updated, and it highlights in yellow the specific text within the guideline that supports the statement. So it addresses the question of trust, it addresses the question of discoverability, and it addresses the question of timeliness. We are really excited to be able to offer that to all of our members simply by logging on to the ASCO member app or going directly to the website at asco.org. GA—the name standing for Guidelines Assistant—is a small but really important step, I think, in our continuing journey to bring optimal, high-quality care to patients everywhere.
The ASCO Post Staff
Alicia Latham, MD, MS, of Memorial Sloan Kettering Cancer Center, discusses the feasibility of using Pap-derived ctDNA for the detection of sporadic and Lynch syndrome–associated endometrial cancer (Abstract 10503).
The ASCO Post Staff
Raffaele Califano, MD, of the Christie NHS Foundation Trust and the University of Manchester, discusses outcomes by osimertinib resistance mechanisms in MARIPOSA-2, a study that evaluated the efficacy of the bispecific antibody amivantamab-vmjw plus chemotherapy vs chemotherapy in patients with EGFR-mutant advanced NSCLC after disease progression on osimertinib (Abstract 8639).
The ASCO Post Staff
David Allen Barbie, MD, of the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute, reviews specific clinical and molecular features of early progressors and long-term progression-free survivors from the phase III ADRIATIC trial, which assessed consolidation durvalumab vs placebo after concurrent chemoradiotherapy for limited-stage small cell lung cancer (Abstract 8014).
The ASCO Post Staff
Andrew J. Armstrong, MD, MS, of Duke Cancer Institute Center for Prostate and Urologic Cancers, Duke University School of Medicine, discusses the 5-year overall survival analysis of the ARCHES trial, which investigated enzalutamide plus androgen-deprivation therapy in patients with metastatic hormone-sensitive prostate cancer (Abstract 5005).
The ASCO Post Staff
Elena Elez, MD, PhD, of Vall d’Hebron Institute of Oncology, presents updated overall survival data as well as progression-free survival data from the BREAKWATER trial of the first-line use of encorafenib, cetuximab, and mFOLFOX6 in BRAF V600E–mutant metastatic colorectal cancer (LBA3500).