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lung cancer

FDA Approves Expanded Use for Erlotinib, Companion Diagnostic to Detect Genetic Mutations in NSCLC

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test, a companion diagnostic for erlotinib (Tarceva). This is the first FDA-approved companion diagnostic that detects epidermal growth factor receptor (EGFR) gene mutations, which are present in approximately 10% of...

lung cancer
issues in oncology

Cryoablation Spot Treats Cancer in the Lung, Extends Survival

Frozen balls of ice can safely kill cancerous tumors that have spread to the lungs, according to the first prospective multicenter trial of cryoablation. The results were presented on April 14, 2013, at the Society of Interventional Radiology’s 38th Annual Scientific Meeting in New Orleans....

lung cancer

Asbestos Exposure, Asbestosis, and Smoking Combined Greatly Increase Lung Cancer Risk

The chances of developing lung cancer associated with asbestos exposure, asbestosis, and smoking are dramatically increased when these three risk factors are combined, and quitting smoking significantly reduces the risk of developing lung cancer after long-term asbestos exposure, according to a new ...

issues in oncology
lung cancer

Leading Health-care Organizations Issue Guideline Recommendations for Molecular Testing and Targeted Therapies

The emergence of molecular diagnostic testing in lung cancer offers new hope for patients battling the number 1 cancer killer in the United States and abroad. Now, for the first time after a decade of biomarker testing in lung cancer, a uniform approach for testing for the EGFR mutation and ALK...

issues in oncology
lung cancer

Cisplatin-resistant Cancer Cells Sensitive to PARP Inhibitors

Poly (ADP-ribose) polymerase (PARP) inhibitors may be a novel treatment strategy for patients with cancer that has become resistant to the commonly used chemotherapy drug cisplatin, according to data from a preclinical study published in Cancer Research, a journal of the American Association for...

lung cancer
issues in oncology

Many Doctors Do Not Provide Tobacco Cessation Assistance to Lung Cancer Patients

Physicians who care for lung cancer patients recognize the importance of tobacco cessation but often do not provide cessation assistance to their patients, according to a recent study published in the Journal of Thoracic Oncology. Survey Details An online survey was conducted in 2012 by the...

lung cancer

Higher Soy Intake Prior to Lung Cancer Diagnosis Linked to Longer Survival in Chinese Women

New results from a large observational follow-up study conducted in Shanghai, China, indicate that women with lung cancer who consumed more soy food prior to their cancer diagnosis lived longer than those who consumed less soy. The study, published March 25 in the Journal of Clinical Oncology,...

lung cancer

Ganetespib Demonstrates Potency against ALK-positive Lung Cancer and Overcomes Crizotinib Resistance

A drug that indirectly impairs the function of several cancer-driving proteins, including anaplastic lymphoma kinase (ALK), may be an effective new treatment for patients with ALK-positive non–small cell lung cancer (NSCLC). The drug, ganetespib, may also be effective for treating patients...

lung cancer

Pathologists Identify Patterns of Mutations to Help Inform Design of Future Trials

Molecular driven therapeutic targets have resulted in a paradigm shift in the treatment of advanced lung adenocarcinoma. However, in early non–small cell lung cancer (NSCLC), surgical resection remains the treatment of choice with adjuvant chemotherapy. In a recent study published in the...

gynecologic cancer
lung cancer
issues in oncology

Tackling Tobacco Consumption and Improving Vaccination Access Are Two of the Best Ways to Reduce Global Cancer Burden

Combatting the tobacco industry’s tactics in the world’s poorest countries as well as ensuring the best cancer vaccines are available to those most in need are key in order to reduce the number of cancer deaths worldwide, according to a new report published in the journal Science...

lung cancer

Patients with NSCLC Have Improved Survival If They Use Beta-blockers While Receiving Radiotherapy

Patients with non–small cell lung cancer (NSCLC) have improved survival outcomes if they are taking beta-blockers while receiving radiotherapy, according to a study of 722 patients recently published in Annals of Oncology. Researchers at the University of Texas MD Anderson Cancer Center in...

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