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lung cancer

ITACA Trial: No Survival Benefit for Tailoring Adjuvant Chemotherapy in NSCLC

Tailoring adjuvant chemotherapy based on the expression of two molecular markers did not lead to a survival advantage in patients with completely resected stage II to III non–small cell lung cancer (NSCLC) in the phase III ITACA trial. This result was presented during the virtual edition of the...

lung cancer

Silvia Novello, MD, PhD, on NSCLC: Pharmacogenomics-Driven vs Standard Adjuvant Chemotherapy

Silvia Novello, MD, PhD, of the University of Turin, discusses phase III results from the ITACA trial, which explored the notion of improving survival by customizing treatment and reducing toxicities for patients with completely resected stage II to IIIA non–small cell lung cancer (Abstract...

lung cancer

Alectinib Yields Favorable Results in Phase III Trials of ALK-Positive NSCLC

RESULTS OF TWO separate phase III trials confirm the activity of alectinib (Alecensa) in the central nervous system (CNS) in patients with anaplastic lymphoma kinase (ALK)-positive non–small cell lung cancer (NSCLC). Results lend support for alectinib as the better first-line treatment option over...

lung cancer

ESMO 2017: ALEX and ALUR Trials: Alectinib Shows CNS Benefit in ALK-Positive NSCLC

Data from two separate phase III studies presented at the European Society for Medical Oncology (ESMO) 2017 Congress in Madrid show the particular central nervous system (CNS) activity of alectinib (Alecensa) in patients with advanced non–small cell lung cancer involving a mutation of the...

lung cancer

Silvia Novello, MD, PhD: Lung Cancer Is a Women's Disease Too

Silvia Novello, MD, PhD, of the University of Turin, discusses a much-neglected aspect of lung cancer: It is not just the province of men; women are affected in great numbers as well.

lung cancer

New Clinical Study Aims to Investigate the Genomics of Young Lung Cancer

The Addario Lung Cancer Medical Institute (ALCMI) recently launched a new study, the Genomics of Young Lung Cancer, to understand why lung cancer occurs in young adults, who quite often are athletic, never smokers and do not exhibit any of the known lung cancer genetic mutations. ALCMI, a...

lung cancer
issues in oncology

One-Quarter of Advanced Lung Cancer Patients Tested for EGFR Mutations Started on First-Line Therapy Before Test Results Available

Almost one in four patients (24%) with advanced lung cancer in Europe, Asia, and the United States are not receiving EGFR test results before being started on treatment, researchers reported at the European Lung Cancer Conference (ELCC) in Geneva (Abstract LBA2_PR). This lack of test results may...

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