Harold J Burstein MD PhD and Lisa A Carey MD
		
		
        
		
		
		
		Harold J. Burstein, MD, PhD, of the Dana-Farber Cancer Institute and Lisa Carey, MD, of the UNC Lineberger Comprehensive Cancer Center, discuss:
- The TNT trial comparing docetaxel to carboplatin
 
- The CALGB trial on response rates after neoadjuvant chemo with or without carboplatin or bevacizumab
 
- Pembrolizumab in a phase Ib study
 
			
			
     	
    
       
       
    		Matthew J. Ellis, MD
		
		
        
		
		
		
		Matthew J. Ellis, MD, PhD, of the Baylor College of Medicine, offers a brief synopsis of his plenary lecture, "Genome-Directed Therapeutics for Endocrine Therapy–Resistant Estrogen Receptor–Positive Breast Cancer."
			
			
     	
    
       
       
    		Jack Cuzick, PhD
		
		
        
		
		
		
		Jack Cuzick, PhD, of the Wolfson Institute of Preventive Medicine, discusses abstract S3-07, "16-year long-term follow-up of the IBIS-I breast cancer prevention trial."
			
			
     	
    
       
       
    		Ismail Jatoi, MD, PhD, FACS, and Ann H. Partridge, MD, MPH
		
		
        
		
		
		
		Ismail Jatoi, MD, PhD, FACS, of the University of Texas Health Science Center and Ann H. Partridge, MD, MPH, of the Dana-Farber Cancer Institute discuss the increasing movement away from breast conservation toward bilateral surgical procedures.