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By Britta Weigelt, PhD, and Jorge S. Reis-Filho, MD, PhD, FRCPath  / September 15, 2014

Sequencing Analysis of Tumor DNA: Is It All in the Plasma?

Massively parallel sequencing analyses have demonstrated that most of the common malignancies display relatively complex repertoires of somatic genetic alterations, that the number of highly recurrent mutations is limited, and that a large number of genes is mutated in a small minority of tumors...