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New Report Underscores Importance of Health Insurance Status and Cancer Stage at Diagnosis in Relation to Patient Survival


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A new report published by Jingxuan Zhao, MPH, and colleagues in CA: A Cancer Journal for Clinicians showed that individuals without health insurance coverage were significantly more likely to be diagnosed with late-stage cancer and have worse survival rates after cancer diagnosis compared to individuals with private health insurance. The study also showed for six cancers—prostate, colorectal, non-Hodgkin lymphoma, oral cavity, liver, and esophageal—uninsured individuals diagnosed with stage I disease had worse survival rates than individuals with private health insurance coverage diagnosed with stage II disease.

“Our findings extend earlier research showing that lack of health insurance coverage is associated with later stage at diagnosis and worse short-term survival among individuals newly diagnosed with cancer, with more recent data and more information on long-term survival,” said Dr. Zhao, who is Senior Associate Scientist at the American Cancer Society. “Improving access to comprehensive health insurance coverage is critical for ensuring access to care throughout the cancer care continuum, including receipt of recommended cancer screening, timely diagnosis, and quality treatment.”

Jingxuan Zhao, MPH

Jingxuan Zhao, MPH

Study Details and Findings

Researchers used data from the U.S. National Cancer Database (NCDB), a nationwide, hospital-based cancer registry jointly sponsored by the American Cancer Society and the American College of Surgeons. The NCDB includes about 70% of all newly diagnosed cancer cases in the United States from more than 1,500 facilities accredited by the American College of Surgeons’ Commission on Cancer. The NCDB contains patient information on demographic characteristics, tumor characteristics, health insurance coverage, and vital status; study authors included data from individuals aged 18 to 64 years who were newly diagnosed with any of 19 common invasive cancers between 2010 through 2013.

The analysis showed people without health insurance coverage were more likely to have a later-stage cancer diagnosis than people with private health insurance coverage. Also, people without health insurance coverage were more likely to have worse short- and long-term survival rates after a cancer diagnosis than people with private health insurance coverage.

Compared to privately insured individuals diagnosed with stage II cancer, uninsured individuals diagnosed with stage I cancer had worse survival rates for six kinds of disease—prostate, colorectal, oral cavity, liver, and esophageal cancers, as well as non-Hodgkin lymphoma. In multivariable analyses, individuals without health insurance had worse survival than their privately insured counterparts within each stage for all the 19 cancers combined and for 14 of 19 cancer sites.

“Our study adds to the accumulating evidence showing access to comprehensive health insurance coverage is crucial to improving cancer care and outcomes,” said William L. Dahut, MD, Chief Scientific Officer at the American Cancer Society. “People should not have to suffer worse survival rates or a later-stage diagnosis because they can’t afford treatment.”

Disclosure: For full disclosures of the study authors, visit acsjournals.onlinelibrary.wiley.com.

The content in this post has not been reviewed by the American Society of Clinical Oncology, Inc. (ASCO®) and does not necessarily reflect the ideas and opinions of ASCO®.
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