Patients with cancer undergoing active treatment were more likely to believe misinformation related to COVID-19 than those without a history of cancer, according to a new study published by Guidry et al in Patient Education and Counseling.

“These findings help us better understand the threat of COVID-19 misinformation in an already-vulnerable population,” said lead author Jeanine Guidry, PhD, Assistant Professor at the Richard T. Robertson School of Media and Culture in the College of Humanities and Sciences at Virginia Commonwealth University (VCU), Director of the Media+Health Lab at VCU, and a member of the Cancer Prevention and Control research program at VCU Massey Cancer Center. “Understanding who is more likely to believe certain types of misinformation brings us closer to understanding why this is the case, which in turn may help us address this concerning issue.”

Survey Results and Implications

Dr. Guidry and colleagues conducted a survey of 897 adults, with roughly one-third undergoing treatment for cancer, one-third cancer survivors not currently in treatment, and one-third respondents with no cancer history. They found that patients currently undergoing cancer treatment were more likely to believe false information about COVID-19 than the other two groups. Least likely to endorse COVID-19 misinformation were cancer survivors no longer in treatment.

“These results highlight that, compared to healthy adults without cancer, cancer survivors currently undergoing treatment may be more vulnerable to COVID-19-related misinformation, while those no longer in treatment are less vulnerable,” the researchers wrote.

Why are patients with cancer more likely to endorse COVID-19 misinformation? The reasons are not entirely clear, the researchers said.

“It may be that survivors currently undergoing treatment have heightened anxiety about how the current pandemic will impact their course of survival, leading them to seek out more information on the internet or via social media, where they are more exposed to misinformation,” they wrote. “Increased information seeking may impact patients’ information-processing abilities, making them more likely to use heuristics or cues, rather than more critical, central processing routes of assessing information credibility.”

The study also found that cancer survivors who are no longer in treatment may have more experience evaluating the veracity of information they read online.

“Our cancer survivors, they’ve gone through this journey and come out the other end, knowing you can’t believe everything you read on the internet—they know you have to talk to your doctor and other people who are knowledgeable about these issues,” said study senior author Bernard Fuemmeler, PhD, Associate Director for Population Science and Gordon D. Ginder, MD, Chair in Cancer Research at VCU Massey Cancer Center, as well as Professor of Health Behavior and Policy at the VCU School of Medicine.

The results build on a previous study by the researchers that found that parents of children with cancer were more likely to believe misinformation and unverifiable content associated with COVID-19 than parents of children with no cancer history.

“Our previous study found that parents of pediatric patients with cancer were more likely to consider misinformation about COVID-19 as true compared to parents of children with no cancer history,” Dr. Guidry said. “While neither of these groups were random population samples, and therefore the findings cannot be generalized, this is still concerning because these are both vulnerable groups, likely already under stress because of cancer diagnoses.”

The new study’s results suggest that oncologists and other providers working with patients undergoing treatment for cancer should be mindful of the patients’ potential susceptibility to misinformation and should help address patients’ concerns about the pandemic and how it relates to their treatment.

“Patients with cancer are in an especially vulnerable position, and it’s our duty as health-care providers to help them weather the ‘infodemic’ of misinformation so they can have the best possible outcome under these challenging circumstances,” said study co-author Robert Winn, MD, Director and Lipman Chair in Oncology at VCU Massey Cancer Center and Senior Associate Dean for Cancer Innovation at the VCU School of Medicine.

Data for the new study was collected prior to the rollout of COVID-19 vaccines. However, Dr. Guidry said, the findings are relevant today.

“The COVID-19 vaccines and boosters so far have been very successful in preventing severe disease and mortality [from] COVID-19, but infection with the virus and its variants is still a possibility, and misinformation about COVID-19 prevention and treatment is still spreading quickly, both online and in person,” she said. “To what extent specific, already vulnerable groups may be susceptible to these types of misinformation remains relevant, both for the remainder of this pandemic as well as for future public health emergencies.”

Disclosure: For full disclosures of the study authors, visit sciencedirect.com.