Radiation Therapy: Hypofractionation vs Conventional Fractionation in Patients With Breast Cancer Planning Breast Reconstruction

1. Hypofractionated radiation therapy was found to be noninferior to conventional fractionation in breast cancer patients undergoing breast reconstruction after mastectomy. 2. It may potentially change the standard of care for postmastectomy radiation therapy. 3. Reduced treatment time to 3 weeks without compromising breast reconstruction achieved low complication rates. 4. The RT CHARM trial enrolled 898 patients with unilateral invasive breast cancer. 5. The median follow-up period was 5 years.