1. Reexcision for wider margins may not be necessary for postmenopausal women with hormone receptor–positive ductal carcinoma in situ (DCIS) treated with breast-conserving surgery, according to the NSABP B-35 trial.
2. Small differences in 10-year ipsilateral breast tumor recurrence rates were found based on margin width.
3. The study prompts reevaluation of margin width guidelines for this specific patient subgroup.
4. DCIS is a type of early-stage breast cancer confined to the milk ducts.
5. The NSABP B-35 trial included postmenopausal women with hormone receptor–positive DCIS between 2003 and 2006, and provided data supporting the potential for less frequent reoperations and improved patient experience without compromising long-term local control outcomes.