The Sarcoma Foundation of America has sponsored the following research projects—each selected through a rigorous peer-review process—in collaboration with the Conquer Cancer Foundation:

• Evaluation of the Hedgehog Signaling Pathway in the Growth of Myogenic Sarcomas
• Targeting the Notch Signaling Pathway: A Novel Method to Inhibit Sarcomas with Constitutive Ras Activation
• Improving the Detection of Osteosarcoma Tumor Margins and Metastasis Using Diagnostic Nanoparticles
• Identification and Characterization of Tumor Initiating Cells in Human Osteosarcoma
• Using Molecular Imaging to Identify Microscopic Residual Sarcoma Cells During Surgery
• Obstruction of Transcription at Tumorigenic Chromosomal Translocations as Therapy
• Examination of the Molecular and Therapeutic Effects of mTOR and PDGFRA Inhibition in Advanced Synovial Sarcoma
• A Phase III, Double-blind, Randomized, Placebo-controlled Trial of Sorafenib in Desmoid Tumors or Aggressive Fibromatosis (DT/DF)
• A Role for Injury in Sarcomagenesis