Pembrolizumab Plus Weekly Paclitaxel Improves Survival Outcomes in Platinum-Resistant Recurrent Ovarian Cancer
By CAROLINE HELWICK
December 10, 2025: Supplement – Conference Highlights ESMO 2025
1. ENGOT-ov65/KEYNOTE-B96 trial combined pembrolizumab with paclitaxel and bevacizumab.
2. Significant improvement in median progression-free survival: 8.3 months vs 7.2 months with placebo.
3. Under FDA priority review as a treatment for platinum-resistant ovarian cancer.
4. Presenting results included high objective response rates and manageable safety profiles.
5. Study emphasizes chemotherapy's role in enhancing antitumor immunity for optimal outcomes.